EYW - STL

$121 Find Cheap Flights from Key West to St. Louis - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$529
Typical prices: $338-$399
United Airlines
Mon 11/12Fri 11/16
EYW - STL • 1 stop
Cheapest one-way
$121
Typical prices: $280-$498
Multiple Airlines
Sat 12/1
EYW - STL • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Key West and St. Louis. You'll need to take a connecting flight to reach the destination.
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Insights
Top layover airports
Charlotte Douglas (CLT)
Cheapest • Avg $308 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 5h 05m (one-way)
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Flight Deals

Cheap Flights from Key West to St. Louis (EYW-STL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Key West to St. Louis

Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
4:10 pm - 11:24 pmEYW  Key West-STL Lambert-St Louis
8h 14m1 stop Chicago O'Hare Intl
United Airlines Logo
8:30 am - 3:29 pmSTL  Lambert-St Louis-EYW Key West
5h 59m1 stop Chicago O'Hare Intl
$529United Airlines
Thu, Nov 26 - Thu, Dec 3
Multiple Airlines Logo
5:30 pm - 5:40 pmEYW  Key West-STL Lambert-St Louis
25h 10m2 stops Fort Lauderdale Atlanta Hartsfield-Jackson
Multiple Airlines Logo
6:13 pm - 10:19 amSTL  Lambert-St Louis-EYW Key West
15h 06m1 stop Orlando
$602Multiple Airlines
Thu, Nov 26 - Thu, Dec 3
American Airlines Logo
1:04 pm - 8:13 amEYW  Key West-STL Lambert-St Louis
20h 09m2 stops Washington, D.C. Reagan-National Charlotte Douglas
American Airlines Logo
9:14 am - 7:30 pmSTL  Lambert-St Louis-EYW Key West
9h 16m2 stops Charlotte Douglas Miami
$652American Airlines
Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
4:10 pm - 11:24 pmEYW  Key West-STL Lambert-St Louis
8h 14m1 stop Chicago O'Hare Intl
United Airlines Logo
5:34 pm - 1:52 pmSTL  Lambert-St Louis-EYW Key West
19h 18m3 stops Chicago O'Hare Intl Madison Truax Field Newark
$732United Airlines
Thu, Nov 26 - Thu, Dec 3
Delta Logo
7:30 am - 1:23 pmEYW  Key West-STL Lambert-St Louis
6h 53m1 stop Atlanta Hartsfield-Jackson
Delta Logo
12:36 pm - 8:01 pmSTL  Lambert-St Louis-EYW Key West
6h 25m1 stop Atlanta Hartsfield-Jackson
$746Delta
Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
4:10 pm - 9:40 pmEYW  Key West-STL Lambert-St Louis
6h 30m1 stop Chicago O'Hare Intl
United Airlines Logo
8:00 am - 1:52 pmSTL  Lambert-St Louis-EYW Key West
28h 52m2 stops Washington, D.C. Dulles Intl Newark
$801United Airlines
Thu, Nov 26 - Thu, Dec 3
United Airlines Logo
11:25 am - 6:05 pmEYW  Key West-STL Lambert-St Louis
31h 40m3 stops Newark Los Angeles San Francisco
United Airlines Logo
2:50 pm - 3:26 pmSTL  Lambert-St Louis-EYW Key West
23h 36m2 stops Denver Intl Chicago O'Hare Intl
$975United Airlines
Booking Insights

Price, demand and travel trends for Key West to St. Louis flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Key West to St. Louis?

Round-trip flights from Key West to St. Louis typically range from $338 to $399. The lowest price found in the past 5 days was $529, on United Airlines.

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Key details for Key West to St. Louis flights

Cheapest flight

$121
One-way flight from Key West to St. Louis

When to book flights from Key West to St. Louis

Are your dates flexible? Find out the best times to travel from Key West to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Key West to St. Louis flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Key West to St. Louis?

    Only Economy Class is available on flights from Key West to St. Louis.

  • How long is a flight from Key West to St. Louis?

    A nonstop flight from Key West to St. Louis takes 00m, covering 1,102 miles.

  • Do I need a passport to fly from Key West to St. Louis?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • Have flight prices from Key West to St. Louis changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $529 to $975. That means the highest observed fare was about 84% higher than the lowest one.

  • How are flight prices from Key West to St. Louis looking right now?

    One-way fares from Key West to St. Louis are currently lower than usual. Average one-way flight prices are about $151, which is 66% below the typical average for this route.

  • What car rental options are available at Lambert-St Louis Airport (STL)?

    Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates averaging $78 for economy cars. Top options include:

    • Hertz
    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Payless

  • Which airports can I use when flying from Key West to St. Louis?

    Flights from Key West to St. Louis usually depart from Key West (EYW) and arrive at Lambert-St Louis (STL).

  • Which airports do connecting flights from Key West to St. Louis pass through?

    Connecting flights from Key West to St. Louis most commonly pass through:

    • Atlanta Hartsfield-Jackson (ATL) - 50% of one-stop connections
    • Charlotte Douglas (CLT) - 50% of one-stop connections

  • Can I save money by using flexible dates for flights from Key West to St. Louis?

    Yes. Flexible dates can save you up to 57% on flights from Key West to St. Louis. Friday is the cheapest departure day at $374 round-trip on average, while Tuesday is the most expensive at $862, a difference of $488.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Key West to St. Louis?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 5h 05m, compared with 5h 27m via Charlotte Douglas (CLT).

  • What is the time difference between Key West and St. Louis?

    St. Louis is 1 hour behind Key West (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in St. Louis?

    Some of the most popular sights in St. Louis are Busch Stadium, Enterprise Center and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

Your guide to booking Key West to St. Louis flights

Get tips on when to book, when to fly and what to know before your trip.

More options for your flight from Key West to St. Louis

Complete your trip to St. Louis with a hotel stay or car rental

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