STL - ECP

$103 Find Cheap Flights from St. Louis to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Panama City departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Panama City, as well as popular online travel agencies
Travelers love KAYAK
41.299.237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$201
Overall average: $413
American Airlines
Wed 3/18Wed 3/25
STL - ECP • 1 stop
Cheapest non-stop
$300
Southwest
Sat 4/18Wed 4/22
STL - ECP • Non-stop
Top airlines
American Airlines
Cheapest • from $201 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Every day
You can fly direct with Southwest. Average duration is 1h 48m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top layover airports
Atlanta (ATL)
Cheapest • Avg $323 (round-trip)
Nashville (BNA)
Shortest trip • 3h 52m (one-way)
Insights
Insights
Insights
Insights
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 45% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
October
Cheapest • 22% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Panama City (STL-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Panama City

Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
6:57 pm - 11:49 pm
STL
-
ECP
4h 52m
1 stop
American Airlines Logo
7:19 am - 12:43 pm
ECP
-
STL
5h 24m
1 stop
$201American Airlines
Wed, Mar 4 - Sat, Mar 7
United Airlines Logo
6:00 am - 12:04 pm
STL
-
ECP
6h 04m
1 stop
United Airlines Logo
12:15 pm - 5:44 pm
ECP
-
STL
5h 29m
1 stop
$205United Airlines
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
6:57 pm - 11:49 pm
STL
-
ECP
4h 52m
1 stop
American Airlines Logo
7:19 am - 3:35 pm
ECP
-
STL
8h 16m
2 stops
$206American Airlines
Tue, Mar 10 - Wed, Mar 11
United Airlines Logo
10:00 am - 9:57 pm
STL
-
ECP
11h 57m
2 stops
United Airlines Logo
10:24 am - 6:00 pm
ECP
-
STL
7h 36m
1 stop
$210United Airlines
Sat, Apr 18 - Wed, Apr 22
United Airlines Logo
4:49 pm - 9:59 pm
STL
-
ECP
5h 10m
1 stop
United Airlines Logo
4:57 pm - 10:28 pm
ECP
-
STL
5h 31m
1 stop
$241United Airlines
Wed, Apr 15 - Sat, Apr 18
United Airlines Logo
9:10 am - 9:59 pm
STL
-
ECP
12h 49m
2 stops
United Airlines Logo
4:57 pm - 10:28 pm
ECP
-
STL
5h 31m
1 stop
$248United Airlines
Sat, Aug 15 - Sat, Aug 22
United Airlines Logo
8:00 am - 7:06 pm
STL
-
ECP
11h 06m
2 stops
United Airlines Logo
4:55 pm - 10:06 pm
ECP
-
STL
5h 11m
1 stop
$260United Airlines
Wed, Mar 11 - Mon, Mar 16
United Airlines Logo
7:40 am - 1:14 pm
STL
-
ECP
5h 34m
1 stop
United Airlines Logo
2:10 pm - 9:07 pm
ECP
-
STL
6h 57m
1 stop
$268United Airlines
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
8:00 am - 12:44 pm
STL
-
ECP
4h 44m
1 stop
American Airlines Logo
1:20 pm - 9:21 pm
ECP
-
STL
8h 01m
1 stop
$272American Airlines
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
6:00 am - 4:04 pm
STL
-
ECP
10h 04m
2 stops
American Airlines Logo
7:19 am - 3:35 pm
ECP
-
STL
8h 16m
2 stops
$274American Airlines
Booking Insights

KAYAK's insights & trends for St. Louis to Panama City flights

Get data-powered insights and trends into flights from St. Louis to Panama City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from St. Louis to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Panama City is October, where tickets cost $280 (return) on average. On the other hand, the most expensive months are March and May, where the average cost of round-trip tickets is $413 and $409 respectively.

Can I save money by flying with a layover from St. Louis to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $303 on average.

How far in advance should I book a flight from St. Louis to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from St. Louis to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from St. Louis to Panama City, you should book around 3 weeks before departure, which saves you about 45% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 4 weeks before departure.

Good to know

Low seasonNovember
Cheapest flight$103
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from St. Louis to Panama City

When to book flights from St. Louis to Panama City

Are your dates flexible? Find out the best times to travel from St. Louis to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Panama City

  • How many flights are there between St. Louis and Panama City per day?

    Each day, there are between 1 and 3 nonstop flights that take off from St. Louis and land in Panama City, with an average flight time of 1h 48m. The most common departure time is 5:00 pm and most flights take off in the morning. Each week, there are 9 flights. The most frequent day of departure is Saturday, when 33% of all weekly flights depart. The fewest flights depart on a Tuesday.

  • What is the cheapest flight from St. Louis to Panama City?

    In the last 3 days, the lowest price for a flight from St. Louis to Panama City was $103 for a one-way ticket and $201 for a round-trip.

  • Do I need a passport to fly between St. Louis and Panama City?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from St. Louis to Panama City?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the St. Louis to Panama City flight route.

  • Which airline alliances offer flights from St. Louis to Panama City?

    oneworld, and SkyTeam are the airline alliances operating flights between St. Louis and Panama City, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from St. Louis to Panama City?

    There are nonstop flights from St. Louis to Panama City on a daily basis.

  • Which is the best airline for flights from St. Louis to Panama City, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from St. Louis to Panama City are Southwest and Delta. With an average price for the route of $415 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $289 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from St. Louis to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from St. Louis to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $377 or less round-trip.

Prefer to fly direct from St. Louis to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Lambert-St Louis to Panama City NW Florida Beaches.
Find which airlines fly direct from Lambert-St Louis Airport to Panama City NW Florida Beaches Airport, which days they fly and book direct flights.

Direct departures

Lambert-St Louis to Panama City NW Florida Beaches

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Panama City NW Florida Beaches to Lambert-St Louis

Monday

Southwest

Southwest

Tuesday

Southwest

Southwest

Wednesday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Reviews of the top 3 airlines serving from St. Louis to Panama City

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4298 reviews
8.1Boarding
7.0Food
7.5Entertainment
8.0Comfort
8.6Crew
Airline reviews

Only downside was the legroom and seat width, which is always a problem unless I spend more for a premium seat.

10.0 ExcellentAnonymous, Feb 2026
STL - DAL
Read more Southwest reviews

Only downside was the legroom and seat width, which is always a problem unless I spend more for a premium seat.

Pretty seamless, just a tad bit late in taking off and landing.

Okay, not wonderful. Short flight. Wi-fi didn't work properly. Stuck waiting for a gate to open upon arrival for 20 or so minutes.

They sent a notice that they were boarding an hour early. We had to leave the club and run to the gate. They said sorry, that came from corporate and was a mistake. They did not have enough seating because the flight before it had not taken off on time. They moved our gate and delayed it for an hour.

Everything a cheap airline should be at normal airline rates.

Delays delays delays. Late taking off, late landing, wait for a gate, etc.

The quality of Southwest Airlines continues to degrade each time I fly with them. If it were not for the free luggage, I would probably choose another airline. Their prices are a little bit competitive, but way too high for the quality of the service. Southwest is not unique in this way. Domestic flight in the United States of America has continued to be a lower and lower quality product. Very sad when you compare the quality of domestic airlines to that of many international airlines around the world.

I'm not a fan of Southwest's model. I don't like the herding style of boarding.

It is southwest seat was ok. Not the most comfortable seat

Plz don't take away free bags and free seating

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

They took all carry-on luggage from Groups 6 -9 - I was group 5 and waiting in line to board - they made me check my luggage too. That then went to baggage claim and delayed departure from the airport. There was overhead room in my seating area - Delta over reacted. Also, had a gentleman next to me that took up 1/2 my seat.

Sorry I didn't realize I was writing a review for each leg. Please see my previous review - it applies to the entire flight, not just a single leg.

boarded at 5:30 pm, pushed away from gate at 6pm ... takeoff was not until ~6:45pm; disappointing

Paid for wifi that didn't work. No plug in seat to work. No entertainment.

The flight was delayed and oversold. I volunteered to give up my seat for compensation. Thinking I could get a good night's sleep instead of arriving home at 2 am. It took over an hour to get the new reservation confirmed, three different gate attendants, and two red coats. It took even longer to confirm the overnight hotel, and when I arrived, the line was 45 minutes long, with two people checking in, and at least 15 people slowly, very slowly—no food except frozen convenience food, no coupon for food from airlines. Slept, headed back to the airport, and that flight had an equipment change and a gate change just as they were about to board. It took an additional hour to board as they cleaned the plane from storage.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Delta is a good airline. I've never had an issue with Delta. I'll continue to fly with them until they show me that I shouldn't.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

We missed our flight and got stranded in Miami where we had to rent a hotel we could not afford. they would not work with us because they said it was weather related even though the gate attendant said it was not. I could go on but trying to get satisfaction has wore me down, which I believe is the intent. My only solution is to never fly AA again.

The flight was really crowded. Flight attendants were just ok.

Didn't get a seat assignment until the last minute even though i picked a seat.

Flight was on time and the meal and service were good.

Old equipment, needs upgrade and seat comfort. Internet didn't work 75% or the time.

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

It was a little concerning to hear the ground crew arguing with the flight crew over baggage space. Instead of taking them and checking them, they started checking for space in the first class cabin moving items around like the flight crew didn't know what they were doing. I was embarrassed for them.

Trip delayed for 2 hours because of rain. We boarded and have to get down the flight and reboard again.

No enough space plus only allowing one laggage instead of two like other airlines.

Qatar airways ,boarding arrangements at Hamid international airport could been better

Everything you need to know for your flight from St. Louis to Panama City

Information on your arrival and departure airports