STL - PTY

$197 Find Cheap Flights from St. Louis to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Panama City departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$415
Typical prices: $452-$553
United Airlines
Wed 4/29Tue 5/5
STL - PTY • 1 stop
Cheapest one-way
$197
Typical prices: $232-$253
American Airlines
Fri 5/29
STL - PTY • 2 stops
Top airlines
United Airlines
Cheapest • from $415 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
April
Cheapest • 22% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Panama City (STL-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Panama City

Wed, Apr 29 - Tue, May 5
United Airlines Logo
6:00 am - 2:14 pm
STL
-
PTY
8h 14m
1 stop
United Airlines Logo
7:55 am - 4:01 pm
PTY
-
STL
8h 06m
1 stop
$415United Airlines
Wed, Apr 29 - Wed, May 6
United Airlines Logo
6:30 am - 6:37 pm
STL
-
PTY
12h 07m
2 stops
United Airlines Logo
7:55 am - 4:01 pm
PTY
-
STL
8h 06m
1 stop
$419United Airlines
Sun, Apr 26 - Tue, May 5
Delta Logo
11:43 am - 1:02 pm
STL
-
PTY
25h 19m
1 stop
Delta Logo
2:27 pm - 11:34 pm
PTY
-
STL
9h 07m
1 stop
$422Delta
Tue, Apr 21 - Sat, Apr 25
United Airlines Logo
6:30 am - 6:37 pm
STL
-
PTY
12h 07m
2 stops
United Airlines Logo
7:55 am - 9:08 pm
PTY
-
STL
13h 13m
2 stops
$423United Airlines
Wed, Mar 11 - Wed, Mar 18
American Airlines Logo
6:57 pm - 12:40 pm
STL
-
PTY
17h 43m
2 stops
American Airlines Logo
1:40 pm - 10:32 am
PTY
-
STL
20h 52m
1 stop
$429American Airlines
Fri, May 1 - Wed, May 6
United Airlines Logo
6:00 am - 6:37 pm
STL
-
PTY
12h 37m
1 stop
United Airlines Logo
7:55 am - 4:01 pm
PTY
-
STL
8h 06m
1 stop
$432United Airlines
Sat, Apr 11 - Wed, Apr 22
United Airlines Logo
7:45 am - 6:37 pm
STL
-
PTY
10h 52m
2 stops
United Airlines Logo
10:00 am - 10:56 pm
PTY
-
STL
12h 56m
2 stops
$436United Airlines
Sun, Apr 26 - Fri, May 8
Delta Logo
4:41 pm - 1:02 pm
STL
-
PTY
20h 21m
1 stop
Delta Logo
2:20 pm - 8:07 am
PTY
-
STL
17h 47m
1 stop
$439Delta
Fri, May 29 - Tue, Jun 2
United Airlines Logo
6:00 pm - 6:37 pm
STL
-
PTY
24h 37m
1 stop
United Airlines Logo
7:55 am - 8:21 pm
PTY
-
STL
12h 26m
1 stop
$440United Airlines
Sun, Apr 26 - Sun, May 3
Delta Logo
11:43 am - 1:02 pm
STL
-
PTY
25h 19m
1 stop
Delta Logo
2:27 pm - 11:56 am
PTY
-
STL
21h 29m
1 stop
$447Delta
Booking Insights

KAYAK's insights & trends for St. Louis to Panama City flights

Get data-powered insights and trends into flights from St. Louis to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from St. Louis to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from St. Louis to Panama City departing in April.

What is the cheapest month to fly from St. Louis to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Panama City is April, where tickets cost $439 (return) on average. On the other hand, the most expensive months are December and February, where the average cost of round-trip tickets is $719 and $616 respectively.

How far in advance should I book a flight from St. Louis to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from St. Louis to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from St. Louis to Panama City, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 15 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$197
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from St. Louis to Panama City

When to book flights from St. Louis to Panama City

Are your dates flexible? Find out the best times to travel from St. Louis to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Panama City

  • What is the cheapest flight from St. Louis to Panama City?

    In the last 3 days, the lowest price for a flight from St. Louis to Panama City was $197 for a one-way ticket and $415 for a round-trip.

  • Do I need a passport to fly between St. Louis and Panama City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in St. Louis and on arrival in Panama City.

  • Which airports will I be using when flying from St. Louis to Panama City?

    St. Louis and Panama City are both served by 1 main airport. You will leave St. Louis from Lambert-St Louis and will be arriving at Panama City Tocumen Intl.

  • Which aircraft models fly most regularly from St. Louis to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from St. Louis to Panama City?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between St. Louis and Panama City, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from St. Louis to Panama City, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from St. Louis to Panama City are Delta and United Airlines. With an average price for the route of $570 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $529 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from St. Louis to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from St. Louis to Panama City

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8124 reviews
7.8Entertainment
7.2Food
8.1Boarding
7.9Comfort
8.5Crew
Airline reviews

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

10.0 ExcellentZebrina, Jan 2026
LGA - CAE
Read more Delta reviews

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

delta last minute gave me a boarding pass for a different flight with no confirmation that they were changing it

The flight was comfortable and uneventful, which is what I desire

The service from the flight attendants were of supreme quality. They greeted and treated everyone with a wide smile. This is totally absent nowadays. Kudos to them!!!!

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Very large passenger too space from my own seat. Arm board couldn’t be lowered because of his size. It wads very uncomfortable trip, as the flight was full couldn’t move anywhere having back pain because of the position in which I was the entire flight.

was sitting in the jet bridge for 10 minutes in -20 degree weather waiting for my bag

Outdated equipment in disrepair, wifi inoperable. Broken seats, taped air vents, generally poor condition, the 717 showed its age and lack of upkeep.

My flight out of Baton Rouge to Atlanta was delayed by a half hour. This got us into Atlanta airport 30 minutes late. I ran through the airport to get to my connecting flight. As I approached the boarding gate, I saw the boarding door was still open and a passenger was being checked in. But when I got to the gate, the boarding agent told me they had already given away my seat and there were no empty seats on that flight. So I had to take a later flight. That has never happened to me before. Very frustrating.

Connection through Atlanta was difficult. Mechanical issue on plane caused a two hour delay. New gate was a mile away.

In overall it was a good experience, the only down point was that the entertainment screen was working properly.

HORRIBLE, my initial flight was cancelled, they made me pay $200 extra dollars and that got cancelled as well! After 6 cancellations I decided to get a refund because I needed to get home to my babies. Out of $1000+ dollars they offered me only $40 in refund! Totally unacceptable! The flight that they cancelled I was able to fly it on another airline. I had to spend $400 on one way tickets just to get home! I’m still getting the runaround.

First class ticket gets you a choice of chips or nuts. . Just like economy Southwest. Also no screen in the seats. This is first class???!

Seated dude next to me even though lots of empty rows. But main thing was we sat on the tarmac after landing for 30 minutes because of, in the words of the dude who sat next to me, “operational incompetence”. We got changing directions about where to pick up gate checked bags. Pilot and flight attendant were awesome though.

The food was terrible this time. Otherwise pleasant, quiet, on-time.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

Flight arrived 30 min early and bag was waiting at the baggage pickup. United Club HNL was one of the nicest in the system

Unfortunately weather delayed our flight waiting for our plane to arrive and due to a little snow time was needed to deice the plane so departure was very delayed and I missed the connecting flight

Very good. Because of the delays with my previous flight, I missed my connection, but I was able to book another flight through the United app easily.

I wish there were outlets to charge my iPhone. The crew was great; we had a female pilot who was great with explaining what was happening and delays,

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

My flight to London from Philadelphia was cancelled due to weather.

The attendants were kind and helpful. A sugar-free drink would have been very welcome.

Pilot navigated severe weather/snow storm with skill. Described his intentions clearly

one crew said "he" didn't serve double alcohol drinks for travelers in exit rows. crew on prior flight did. Is this a AA rule, and the prior crew was being nice? Also, I think we deserve more than a 25% refund for losing first class seats when rescheduling a flight due to weather

It was a little concerning to hear the ground crew arguing with the flight crew over baggage space. Instead of taking them and checking them, they started checking for space in the first class cabin moving items around like the flight crew didn't know what they were doing. I was embarrassed for them.

2 hour delay due to equipment failure. No updates via the app and airport screens (which continued to show a departure time in the past). AA eventually switched planes and the new plane was not catered or cleaned correctly.

I booked an aisle seat and was given a middle. At 6'4" 230lbs, it is not ideal to fly in the middle row for myself and passengers.

Everything you need to know for your flight from St. Louis to Panama City

Information on your arrival and departure airports