STL - PTY

$266 Find Cheap Flights from St. Louis to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Panama City departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$525
Typical prices: $680-$517
United Airlines
Thu 5/28Tue 6/2
STL - PTY • 1 stop
Cheapest one-way
$266
Typical prices: $273-$289
United Airlines
Thu 6/11
STL - PTY • 1 stop
Top airlines
Cheapest • from $525 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between St. Louis and Panama City. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $625 (round-trip)
Shortest trip • 7h 09m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 15% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Panama City (STL-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Panama City

Thu, May 28 - Tue, Jun 2
United Airlines Logo
6:00 am - 7:31 pm
STL
-
PTY
13h 31m
1 stop
United Airlines Logo
3:30 pm - 10:07 am
PTY
-
STL
18h 37m
1 stop
$525United Airlines
Thu, May 28 - Tue, Jun 2
United Airlines Logo
6:00 am - 7:31 pm
STL
-
PTY
13h 31m
1 stop
United Airlines Logo
3:30 pm - 8:41 am
PTY
-
STL
17h 11m
2 stops
$529United Airlines
Sun, Sep 6 - Mon, Sep 14
Delta Logo
5:30 pm - 1:13 pm
STL
-
PTY
19h 43m
1 stop
Delta Logo
2:21 pm - 8:06 am
PTY
-
STL
17h 45m
1 stop
$533Delta
Wed, Jul 22 - Tue, Jul 28
United Airlines Logo
6:01 am - 4:04 am
STL
-
PTY
22h 03m
1 stop
United Airlines Logo
9:45 am - 11:36 pm
PTY
-
STL
13h 51m
1 stop
$534United Airlines
Wed, Jul 22 - Tue, Jul 28
United Airlines Logo
6:01 am - 4:04 am
STL
-
PTY
22h 03m
1 stop
United Airlines Logo
3:30 pm - 8:41 am
PTY
-
STL
17h 11m
2 stops
$539United Airlines
Sun, Aug 2 - Mon, Aug 10
United Airlines Logo
6:01 am - 7:31 pm
STL
-
PTY
13h 30m
1 stop
United Airlines Logo
9:45 am - 11:45 pm
PTY
-
STL
14h 00m
1 stop
$542United Airlines
Thu, Oct 15 - Sat, Oct 24
United Airlines Logo
6:15 am - 6:37 pm
STL
-
PTY
12h 22m
1 stop
United Airlines Logo
3:30 pm - 8:37 am
PTY
-
STL
17h 07m
2 stops
$546United Airlines
Mon, Sep 7 - Sun, Sep 13
Delta Logo
6:00 am - 1:13 pm
STL
-
PTY
7h 13m
1 stop
Delta Logo
2:21 pm - 12:53 pm
PTY
-
STL
22h 32m
1 stop
$550Delta
Sun, Aug 2 - Mon, Aug 10
United Airlines Logo
6:01 am - 7:31 pm
STL
-
PTY
13h 30m
1 stop
United Airlines Logo
10:55 pm - 11:37 pm
PTY
-
STL
24h 42m
1 stop
$551United Airlines
Sun, Oct 18 - Sun, Oct 25
United Airlines Logo
6:49 pm - 2:14 pm
STL
-
PTY
19h 25m
2 stops
United Airlines Logo
3:41 pm - 10:06 pm
PTY
-
STL
30h 25m
1 stop
$556United Airlines
Booking Insights

KAYAK's insights & trends for St. Louis to Panama City flights

Get data-powered insights and trends into flights from St. Louis to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from St. Louis to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from St. Louis to Panama City departing in May.

What is the cheapest month to fly from St. Louis to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Panama City is April, where tickets cost $495 (return) on average. On the other hand, the most expensive months are December and February, where the average cost of round-trip tickets is $719 and $684 respectively.

Good to know

Low seasonSeptember
Cheapest flight$266
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 3% increase in price.
Flight from St. Louis to Panama City

When to book flights from St. Louis to Panama City

Are your dates flexible? Find out the best times to travel from St. Louis to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to Panama City

  • What is the cheapest flight from St. Louis to Panama City?

    In the last 3 days, the lowest price for a flight from St. Louis to Panama City was $266 for a one-way ticket and $525 for a round-trip.

  • Do I need a passport to fly between St. Louis and Panama City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in St. Louis and on arrival in Panama City.

  • Which airports will I be using when flying from St. Louis to Panama City?

    St. Louis and Panama City are both served by 1 main airport. You will leave St. Louis from Lambert-St Louis and will be arriving at Panama City Tocumen Intl.

  • Which aircraft models fly most regularly from St. Louis to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from St. Louis to Panama City?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between St. Louis and Panama City, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from St. Louis to Panama City, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from St. Louis to Panama City are Delta and United Airlines. With an average price for the route of $590 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $569 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from St. Louis to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from St. Louis to Panama City

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8463 reviews
8.5Crew
8.1Boarding
7.2Food
7.9Comfort
7.8Entertainment
Airline reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

6.0 GoodSilvestre, Apr 2026
MCO - GRU
Read more Delta reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

Some crew were unfriendly or in some cases just straight up rude.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

Standard flight with a drinks and a snack- overall very quick flight. The flight attendants were very strict, bordered on rude.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

United Airline crews were very friendly and very attentive. 12 hours flight was gone like in a shorter one.

Delayed - weather wasn't bad at either end. Also sat on tarmac in ORD.

Food was surprisingly delicious. Space in the seat is horrible when the seating front is reclined. Movie offerings were terrible. Crew was friendly and helpful.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

This was a hard flight. 3 delays out of OKC (1 on the Tarmac). Delay in Atlanta coming to Dallas. total travel time was the equivalent of driving from OKC to Atlanta.

Like: flights are on time, good boarding process Can improve: planes are old, improve entertainment and make space more comfortable

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

Everything you need to know for your flight from St. Louis to Panama City

Information on your arrival and departure airports