PTY - STL

$312 Find Cheap Flights from Panama City to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to St. Louis departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$537
Typical prices: $391-$555
United Airlines
Tue 12/16Tue 2/10
PTY - STL • 1 stop
Cheapest one-way
$312
Typical prices: $348-$421
United Airlines
Tue 12/16
PTY - STL • 1 stop
Top airlines
United Airlines
Cheapest • from $537 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
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+1
Airline reviews
Airline reviews
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We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to St. Louis (PTY-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to St. Louis

Tue, Dec 16 - Tue, Feb 10
United Airlines Logo
8:55 am - 4:04 pmPTY-STL
8h 09m1 stop
United Airlines Logo
10:07 am - 7:38 pmSTL-PTY
8h 31m1 stop
$537United Airlines
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Fri, May 1 - Tue, May 5
Delta Logo
2:20 pm - 11:38 pmPTY-STL
9h 18m1 stop
Delta Logo
6:00 am - 12:55 pmSTL-PTY
6h 55m1 stop
$546Delta
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Fri, May 1 - Tue, May 5
United Airlines Logo
10:55 pm - 3:21 pmPTY-STL
16h 26m2 stops
United Airlines Logo
6:15 am - 2:14 pmSTL-PTY
7h 59m1 stop
$551United Airlines
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Mon, Dec 29 - Sat, Jan 10
United Airlines Logo
4:41 pm - 9:55 pmPTY-STL
30h 14m1 stop
United Airlines Logo
4:35 pm - 5:07 pmSTL-PTY
23h 32m1 stop
$558United Airlines
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Mon, Dec 29 - Sat, Jan 10
American Airlines Logo
2:53 pm - 10:35 pmPTY-STL
8h 42m1 stop
American Airlines Logo
10:00 am - 1:27 pmSTL-PTY
26h 27m1 stop
$600American Airlines
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Mon, Jan 12 - Mon, Jan 19
United Airlines Logo
4:41 pm - 9:22 amPTY-STL
17h 41m1 stop
United Airlines Logo
6:00 am - 7:38 pmSTL-PTY
12h 38m1 stop
$602United Airlines
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Mon, Dec 29 - Sat, Jan 10
American Airlines Logo
4:55 pm - 1:23 pmPTY-STL
21h 28m2 stops
American Airlines Logo
3:54 pm - 1:27 pmSTL-PTY
20h 33m2 stops
$605American Airlines
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Mon, Dec 15 - Tue, Feb 10
Multiple Airlines Logo
2:55 am - 1:50 pmPTY-STL
35h 55m2 stops
Multiple Airlines Logo
7:00 am - 4:39 pmSTL-PTY
8h 39m1 stop
$879Multiple Airlines
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Tue, Dec 16 - Tue, Feb 10
Multiple Airlines Logo
9:45 am - 3:29 pmPTY-STL
30h 44m3 stops
Multiple Airlines Logo
4:05 pm - 12:40 amSTL-PTY
31h 35m3 stops
$985Multiple Airlines
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Sun, Jan 11 - Mon, Jan 19
Multiple Airlines Logo
2:55 am - 10:33 pmPTY-STL
20h 38m2 stops
Multiple Airlines Logo
6:05 am - 9:42 amSTL-PTY
26h 37m1 stop
$987Multiple Airlines
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Booking Insights

KAYAK's insights & trends for Panama City to St. Louis flights

Get data-powered insights and trends into flights from Panama City to St. Louis to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to St. Louis?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to St. Louis departing in December.

What’s the cheapest day of the week to fly from Panama City to St. Louis?

The average price of all round-trip flights from Panama City to St. Louis clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to St. Louis, you should consider leaving on a Thursday and avoid Wednesdays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Tuesdays and the most expensive ones on Sundays.

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Good to know

Low seasonJune
Cheapest flight$312
Best time to beat the crowds with an average 33% drop in price.
Most popular time to fly with an average 3% increase in price.
Flight from Panama City to St. Louis

When to book flights from Panama City to St. Louis

Are your dates flexible? Find out the best times to travel from Panama City to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to St. Louis

  • What is the cheapest flight from Panama City to St. Louis?

    In the last 3 days, the lowest price for a flight from Panama City to St. Louis was $312 for a one-way ticket and $537 for a round-trip.

  • Do I need a passport to fly between Panama City and St. Louis?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Panama City and on arrival in St. Louis.

  • Which airports will I be using when flying from Panama City to St. Louis?

    On your way to St. Louis, you’ll fly out from Panama City Tocumen Intl. You’ll be landing at Lambert-St Louis.

  • Which aircraft models fly most regularly from Panama City to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to St. Louis?

    Star Alliance is the only airline alliance operating flights between Panama City and St. Louis.

  • How does KAYAK find such low prices on flights from Panama City to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Panama City with another airline. Booking your flights between Panama City and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Panama City to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9015 reviews
7.3Comfort
7.1Entertainment
6.6Food
7.7Boarding
8.1Crew
Airline reviews

Great crew, excellent landing, good food. Over all great experience. Thank you!

8.0 ExcellentSemra, Nov 2025GVA - IAD
Read more United Airlines reviews

Great crew, excellent landing, good food. Over all great experience. Thank you!

Older aircraft, no meal, only food was for purchase. Not impressed United.

United needs to step up their game. Delayed flight leaving Seattle, San Francisco. Older aircraft, not very comfortable.

Always wish for more healthy, gluten free options. We have to bring our own.

Having a long layover, I was very appreciative of the ability to stand by for an earlier flight. Other airlines like Delta have refused this to me in the past, just to be mean (because my ticket class wasn't high enough). United went out of their way to help me get to my destination early, which I really appreciated given that it was the third leg of a 24+ hour journey for me.

This flight leg was fantastic - super comfortable and a great selection of things to watch on the TV. Staff were excellent, really above and beyond.

Other than a way way too cold cabinets for the entire flight, all was great

One bag is incorrect and not acceptable for an international flight. The food was not just good. I won't fly with them again.

The flight attendants were very rude, beyond comprehension. I took a business class from London to SFO for the first time on United. When I asked for a second piece of bread during dinner, the serving attendant threw a 3rd bread on my plate and said, “here. You can have this one too”! I couldn’t believe the rudeness of the attendant. Most all attendants were very rude, unhelpful, sing the food was absolutely disgusting. Never fly United internationally in business class. My flight back to SFO was a nightmare!!

Not pleasant trip cross country when the entertainment and WiFi system not working. No entertainment for entirety of route. Staff was rather nonchalant in that they dismissed the problem due to age of plane. It would have been nice to know this up front so I could have come prepared to read or download movies before boarding Coincidentally or not, there was a similar issue with the entertainment system on my previous flight I took on my fist leg of the trip. There are no seat TVs, so you must rely on the app when it works. United can do better. Also, what use it it to pay for boarding group 2 when half of the passengers are in the same line as you?

Everything you need to know for your flight from Panama City to St. Louis

Information on your arrival and departure airports

Panama City (PTY)
St. Louis (STL)