PTY - STL

$320 Find Cheap Flights from Panama City to St. Louis - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to St. Louis departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$675
Typical prices: $671-$312
United Airlines
Thu 8/6Tue 8/18
PTY - STL • 1 stop
Cheapest one-way
$320
Typical prices: $315-$390
Multiple Airlines
Tue 9/1
PTY - STL • 3 stops
Top airlines
United Airlines
Cheapest • from $675 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Panama City and St. Louis. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Miami (MIA)
Cheapest • Avg $567 (round-trip)
Miami (MIA)
Shortest trip • 8h 28m (one-way)
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 40% price drop
August
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to St. Louis (PTY-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to St. Louis

Thu, Aug 6 - Tue, Aug 18
United Airlines Logo
9:45 am - 11:44 pm
PTY
-
STL
13h 59m
1 stop
United Airlines Logo
12:27 pm - 4:04 am
STL
-
PTY
15h 37m
1 stop
$675United Airlines
Thu, Aug 6 - Tue, Aug 18
United Airlines Logo
7:55 am - 11:29 pm
PTY
-
STL
15h 34m
2 stops
United Airlines Logo
12:59 pm - 4:04 am
STL
-
PTY
15h 05m
2 stops
$680United Airlines
Sun, Sep 6 - Thu, Sep 10
United Airlines Logo
9:45 am - 11:38 pm
PTY
-
STL
13h 53m
1 stop
United Airlines Logo
7:00 am - 7:31 pm
STL
-
PTY
12h 31m
1 stop
$699United Airlines
Tue, Jul 14 - Fri, Jul 17
Multiple Airlines Logo
10:25 am - 8:57 am
PTY
-
STL
22h 32m
2 stops
Multiple Airlines Logo
4:57 pm - 8:34 pm
STL
-
PTY
27h 37m
1 stop
$700Multiple Airlines
Thu, Oct 29 - Sun, Nov 1
United Airlines Logo
9:30 am - 8:37 am
PTY
-
STL
23h 07m
2 stops
United Airlines Logo
6:15 am - 7:38 pm
STL
-
PTY
12h 23m
1 stop
$712United Airlines
Sun, Jul 26 - Sun, Aug 2
United Airlines Logo
10:55 pm - 11:44 pm
PTY
-
STL
24h 49m
1 stop
United Airlines Logo
5:59 pm - 4:12 pm
STL
-
PTY
22h 13m
2 stops
$720United Airlines
Thu, Nov 5 - Sun, Nov 8
American Airlines Logo
2:43 pm - 12:37 pm
PTY
-
STL
22h 54m
2 stops
American Airlines Logo
1:52 pm - 1:36 pm
STL
-
PTY
22h 44m
2 stops
$727American Airlines
Fri, Jul 3 - Sat, Jul 11
Multiple Airlines Logo
9:48 pm - 5:37 pm
PTY
-
STL
43h 49m
2 stops
Multiple Airlines Logo
4:57 pm - 8:34 pm
STL
-
PTY
27h 37m
1 stop
$734Multiple Airlines
Tue, Jul 14 - Fri, Jul 17
United Airlines Logo
7:55 am - 9:26 pm
PTY
-
STL
13h 31m
2 stops
United Airlines Logo
7:05 pm - 2:14 pm
STL
-
PTY
19h 09m
2 stops
$741United Airlines
Mon, Jun 29 - Mon, Jul 6
United Airlines Logo
7:55 am - 8:42 pm
PTY
-
STL
12h 47m
1 stop
United Airlines Logo
6:14 am - 6:37 pm
STL
-
PTY
12h 23m
1 stop
$752United Airlines
Booking Insights

KAYAK's insights & trends for Panama City to St. Louis flights

Get data-powered insights and trends into flights from Panama City to St. Louis to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to St. Louis?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to St. Louis departing in August.

What is the cheapest month to fly from Panama City to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to St. Louis is March, where tickets cost $360 (return) on average. On the other hand, the most expensive months are May and June, where the average cost of round-trip tickets is $825 and $773 respectively.

Find deals

Good to know

Low seasonSeptember
Cheapest flight$320
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 5% increase in price.
Flight from Panama City to St. Louis

When to book flights from Panama City to St. Louis

Are your dates flexible? Find out the best times to travel from Panama City to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to St. Louis

  • What is the cheapest flight from Panama City to St. Louis?

    In the last 5 days, the lowest price for a flight from Panama City to St. Louis was $320 for a one-way ticket and $675 for a round-trip.

  • Do I need a passport to fly between Panama City and St. Louis?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Panama City and on arrival in St. Louis.

  • Which airports will I be using when flying from Panama City to St. Louis?

    On your way to St. Louis, you’ll fly out from Panama City Tocumen Intl. You’ll be landing at Lambert-St Louis.

  • Which aircraft models fly most regularly from Panama City to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to St. Louis?

    Star Alliance is the only airline alliance operating flights between Panama City and St. Louis.

  • How does KAYAK find such low prices on flights from Panama City to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Panama City with another airline. Booking your flights between Panama City and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Panama City to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9842 reviews
8.1Crew
7.7Boarding
7.3Comfort
7.1Entertainment
6.6Food
Airline reviews

The flight got delayed. They forgot to bring the drinks when I asked for it. The toilet is messy.

6.0 GoodAnonymous, Jun 2026
TPE - SFO
Read more United Airlines reviews

The flight got delayed. They forgot to bring the drinks when I asked for it. The toilet is messy.

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

The entertainment is a bit limited, it would be better if they added some games to play besides the movies and tv shows. But the seats are comfortable and the crew is polite

This planes staff was top tier. Everything went great and had a great flight home.

Food was great. Staff was phenomenal. Seats were a bit hard and could use a lot more entertainment options as far as movies to choose from. WiFi was good. Overall great trip.

This was an overnight flight, and in the morning they did know coffee service. How you can throw passengers in a San Francisco airport at 5:40 a.m. in the morning and not giving them Coffee is a crime.

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

The pilot had to extend the flight time from san antonio to Houston to burn off fuel. This caused a lot of unnecessary stress since we had a tight connection to Aruba. And with no other flights going to Aruba we were worried about spending a night in Houston. We had to to run to our connection because of the flight crews mistake. Not happy.

Service was professional and quick. Premium economy seat was comfortable given the class

I'm a United 1K member and have ben for 10 years. The gate agent had no control over the boarding process and had us passengers queued for hours as delays were announced. On the plane, the overhead air nozzle was broken so col over was powering through on me and the passenger next to me. Not a great experience for a million miler on United. Feel free to contact me. Josh Smigel - DM426089

Everything you need to know for your flight from Panama City to St. Louis

Information on your arrival and departure airports

Panama City (PTY)
St. Louis (STL)