PTY - STL

$317 Find Cheap Flights from Panama City to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to St. Louis departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$516
Typical prices: $312-$546
United Airlines
mar. 2/17lun. 2/23
PTY - STL • 1 stop
Cheapest one-way
$317
United Airlines
jue. 1/22
PTY - STL • 1 stop
When to travel
June
Cheapest • 33% price drop
August
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to St. Louis (PTY-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to St. Louis

mar., feb. 17 - lun., feb. 23
United Airlines Logo
8:55 am - 10:14 pm
PTY
-
STL
14h 19m1 stop
United Airlines Logo
4:49 pm - 2:45 pm
STL
-
PTY
20h 56m2 stops
$516United Airlines
sáb., feb. 14 - mar., feb. 24
United Airlines Logo
4:41 pm - 10:36 am
PTY
-
STL
18h 55m2 stops
United Airlines Logo
6:00 am - 5:07 pm
STL
-
PTY
10h 07m1 stop
$537United Airlines
dom., feb. 8 - mar., feb. 24
American Airlines Logo
4:50 pm - 9:24 am
PTY
-
STL
17h 34m2 stops
American Airlines Logo
5:55 pm - 1:50 pm
STL
-
PTY
18h 55m2 stops
$556American Airlines
sáb., feb. 14 - vie., feb. 27
United Airlines Logo
4:41 pm - 10:36 am
PTY
-
STL
18h 55m2 stops
United Airlines Logo
6:00 am - 2:45 pm
STL
-
PTY
7h 45m1 stop
$558United Airlines
jue., feb. 19 - mié., feb. 25
Multiple Airlines Logo
2:55 am - 12:27 am
PTY
-
STL
22h 32m2 stops
Multiple Airlines Logo
8:17 pm - 8:34 pm
STL
-
PTY
23h 17m1 stop
$560Multiple Airlines
jue., feb. 19 - mié., feb. 25
Multiple Airlines Logo
2:55 am - 12:27 am
PTY
-
STL
22h 32m2 stops
Multiple Airlines Logo
8:17 pm - 8:34 pm
STL
-
PTY
23h 17m1 stop
$561Multiple Airlines
jue., feb. 19 - sáb., feb. 28
Multiple Airlines Logo
2:55 am - 12:27 am
PTY
-
STL
22h 32m2 stops
Multiple Airlines Logo
8:17 pm - 8:34 pm
STL
-
PTY
23h 17m1 stop
$562Multiple Airlines
vie., feb. 20 - lun., feb. 23
United Airlines Logo
8:55 am - 10:14 pm
PTY
-
STL
14h 19m1 stop
United Airlines Logo
6:00 am - 2:45 pm
STL
-
PTY
7h 45m1 stop
$580United Airlines
jue., feb. 19 - vie., feb. 27
Multiple Airlines Logo
2:55 am - 12:27 am
PTY
-
STL
22h 32m2 stops
Multiple Airlines Logo
8:17 pm - 8:34 pm
STL
-
PTY
23h 17m1 stop
$581Multiple Airlines
jue., feb. 19 - vie., feb. 27
Multiple Airlines Logo
2:55 am - 12:27 am
PTY
-
STL
22h 32m2 stops
Multiple Airlines Logo
8:17 pm - 8:34 pm
STL
-
PTY
23h 17m1 stop
$582Multiple Airlines
Booking Insights

KAYAK's insights & trends for Panama City to St. Louis flights

Get data-powered insights and trends into flights from Panama City to St. Louis to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to St. Louis?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to St. Louis departing in February.

What’s the cheapest day of the week to fly from Panama City to St. Louis?

The average price of all round-trip flights from Panama City to St. Louis clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to St. Louis, you should consider leaving on a Thursday and avoid Wednesdays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Tuesdays and the most expensive ones on Sundays.

What is the cheapest month to fly from Panama City to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to St. Louis is June, where tickets cost $362 (return) on average. On the other hand, the most expensive months are July and August, where the average cost of round-trip tickets is $659 and $628 respectively.

Find deals

Good to know

Low seasonApril
Cheapest flight$317
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 16% increase in price.
Flight from Panama City to St. Louis

When to book flights from Panama City to St. Louis

Are your dates flexible? Find out the best times to travel from Panama City to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to St. Louis

  • What is the cheapest flight from Panama City to St. Louis?

    In the last 3 days, the lowest price for a flight from Panama City to St. Louis was $317 for a one-way ticket and $516 for a round-trip.

  • Do I need a passport to fly between Panama City and St. Louis?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Panama City and on arrival in St. Louis.

  • Which airports will I be using when flying from Panama City to St. Louis?

    On your way to St. Louis, you’ll fly out from Panama City Tocumen Intl. You’ll be landing at Lambert-St Louis.

  • Which aircraft models fly most regularly from Panama City to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to St. Louis?

    Star Alliance is the only airline alliance operating flights between Panama City and St. Louis.

  • How does KAYAK find such low prices on flights from Panama City to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Panama City with another airline. Booking your flights between Panama City and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Panama City to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9095 reviews
7.3Comfort
7.1Entertainment
6.6Food
7.7Boarding
8.1Crew
Airline reviews

The flight was on time. I generally don’t drink or eat on short flights and the seats were good and the flight attendants were friendly. That’s all I expect

10.0 ExcellentRoger, Dec 2025
CAE - ORD
Read more United Airlines reviews

The flight was on time. I generally don’t drink or eat on short flights and the seats were good and the flight attendants were friendly. That’s all I expect

Movie selection is good. Crew did not understand mileage program and were no help. Sick later. Food?

Staff on board was excellent. Positive upbeat helpful- like it used to be.

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

For an expensive flight to another country, United has a lot of nerve serving pretzels and no meals (unless, of course, you want to buy something to eat). Unacceptable.

The food is terrible. The same pasta or chicken with bad taste and presentation

United have really come back. Airport and boarding process is clear and good, app and information also very good

The Sears in the 800s are not too good perfect Airbus why cant the new 737 fix that

Flight was delayed 8 times. We were sitting at the airport for 14 hours. We got 2 hours of sleep (if that) on what was not meant to be a red-eye.

It was probably one of the worst flights I’ve been on. The restrooms were never cleaned or stocked. The food was very subpar, and i usually enjoy airline food, so I was disappointed. It was just all around a bad experience. The only saving grace was the flight attendants.

Everything you need to know for your flight from Panama City to St. Louis

Information on your arrival and departure airports

Panama City (PTY)
St. Louis (STL)