PTY - STL

$339 Find Cheap Flights from Panama City to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to St. Louis departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$538
Overall average: $559
United Airlines
Tue 2/24Tue 3/3
PTY - STL • 1 stop
Cheapest one-way
$339
Typical prices: $491-$529
Avianca
Fri 1/23
PTY - STL • 2 stops
When to travel
June
Cheapest • 35% price drop
August
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to St. Louis (PTY-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to St. Louis

Tue, Feb 24 - Tue, Mar 3
United Airlines Logo
4:41 pm - 9:23 am
PTY
-
STL
17h 42m
1 stop
United Airlines Logo
4:28 pm - 2:45 pm
STL
-
PTY
21h 17m
1 stop
$538United Airlines
Sat, Feb 14 - Mon, Mar 2
United Airlines Logo
4:41 pm - 10:36 am
PTY
-
STL
18h 55m
2 stops
United Airlines Logo
6:55 pm - 8:02 pm
STL
-
PTY
24h 07m
2 stops
$559United Airlines
Sat, May 30 - Tue, Jun 2
United Airlines Logo
9:45 am - 8:14 pm
PTY
-
STL
10h 29m
1 stop
United Airlines Logo
6:15 am - 4:12 pm
STL
-
PTY
9h 57m
1 stop
$568United Airlines
Sat, May 30 - Tue, Jun 2
United Airlines Logo
10:55 pm - 3:21 pm
PTY
-
STL
16h 26m
2 stops
United Airlines Logo
6:15 am - 4:12 pm
STL
-
PTY
9h 57m
1 stop
$573United Airlines
Sat, May 30 - Tue, Jun 2
United Airlines Logo
10:55 pm - 3:21 pm
PTY
-
STL
16h 26m
2 stops
United Airlines Logo
8:00 am - 6:37 pm
STL
-
PTY
10h 37m
2 stops
$594United Airlines
Wed, Feb 4 - Sat, Feb 7
United Airlines Logo
4:41 pm - 12:29 pm
PTY
-
STL
20h 48m
2 stops
United Airlines Logo
4:49 pm - 5:07 pm
STL
-
PTY
23h 18m
2 stops
$616United Airlines
Wed, Feb 4 - Sat, Feb 7
United Airlines Logo
9:55 am - 9:22 am
PTY
-
STL
24h 27m
1 stop
United Airlines Logo
4:42 pm - 5:07 pm
STL
-
PTY
23h 25m
1 stop
$631United Airlines
Wed, Feb 4 - Sat, Feb 7
United Airlines Logo
4:41 pm - 12:29 pm
PTY
-
STL
20h 48m
2 stops
United Airlines Logo
4:49 pm - 2:45 pm
STL
-
PTY
20h 56m
2 stops
$637United Airlines
Wed, Feb 4 - Sat, Feb 7
United Airlines Logo
11:35 am - 9:22 am
PTY
-
STL
22h 47m
1 stop
United Airlines Logo
4:42 pm - 2:45 pm
STL
-
PTY
21h 03m
1 stop
$653United Airlines
Wed, Feb 25 - Fri, Feb 27
United Airlines Logo
11:35 am - 10:14 pm
PTY
-
STL
11h 39m
1 stop
United Airlines Logo
6:00 am - 2:45 pm
STL
-
PTY
7h 45m
1 stop
$675United Airlines
Booking Insights

KAYAK's insights & trends for Panama City to St. Louis flights

Get data-powered insights and trends into flights from Panama City to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Panama City to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to St. Louis is June, where tickets cost $362 (return) on average. On the other hand, the most expensive months are January and July, where the average cost of round-trip tickets is $664 and $659 respectively.

Find deals

Good to know

Low seasonApril
Cheapest flight$339
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly with an average 12% increase in price.
Flight from Panama City to St. Louis

When to book flights from Panama City to St. Louis

Are your dates flexible? Find out the best times to travel from Panama City to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to St. Louis

  • What is the cheapest flight from Panama City to St. Louis?

    In the last 3 days, the lowest price for a flight from Panama City to St. Louis was $298 for a one-way ticket and $538 for a round-trip.

  • Do I need a passport to fly between Panama City and St. Louis?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Panama City and on arrival in St. Louis.

  • Which airports will I be using when flying from Panama City to St. Louis?

    On your way to St. Louis, you’ll fly out from Panama City Tocumen Intl. You’ll be landing at Lambert-St Louis.

  • Which aircraft models fly most regularly from Panama City to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to St. Louis?

    Star Alliance is the only airline alliance operating flights between Panama City and St. Louis.

  • How does KAYAK find such low prices on flights from Panama City to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Panama City with another airline. Booking your flights between Panama City and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Panama City to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9143 reviews
7.7Boarding
6.6Food
8.1Crew
7.1Entertainment
7.3Comfort
Airline reviews

Both flights delayed. 2nd flight over 3 hours late mechanical issues

2.0 MediocreJose, Jan 2026
PVR - SFO
Read more United Airlines reviews

Both flights delayed. 2nd flight over 3 hours late mechanical issues

l really enjoy very much the flight was very pleasant

left on time, reasonable boarding process arrived early luggage came out quickly

I like flying first class, and United has a nice one

Flight was delayed 45 minutes because originating flight was coming from Newark. No complimentary snacks were offered on this 5+ hour flight. No screens for the flight, but movies offered if you had already downloaded the United app (which I hadn't on my ipad). No USB ports, only a flimsy plug-in port near the bottom of the seat that was hard to see and kept coming unplugged.

It was good but only meal served is very less. Meantime good to add rice and chicken in one of meal

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

Check-in, boarding and the flight from Phoenix to Houston was quick and easy. The flight from Houston to Shreveport was delayed 5 hours. It was frustrating but I think United handled it the best they could.

They lost my luggage, so, not happy. The crew was nice but my suitcases never made it, still trying to find out what happened!

The staff was hospitable and professional. The seat had a bit of wear. The winner shade was stuck 1/4 open. I received the best of both worlds. The morning sun was able to come in and blind the screen i was trying to use while at the same time it was too low to look out and enjoy the view. Rather embarrassing for a 1st class ticket.

Everything you need to know for your flight from Panama City to St. Louis

Information on your arrival and departure airports

Panama City (PTY)
St. Louis (STL)