PTY - STL

$409 Find Cheap Flights from Panama City to St. Louis - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$723
Typical prices: $559-$781
United Airlines
Sun 10/14Thu 10/18
PTY - STL • 1 stop
Cheapest one-way
$409
Typical prices: $388-$529
United Airlines
Fri 12/21
PTY - STL • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Panama City and St. Louis. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
October
Cheapest • 17% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Miami (MIA)
Cheapest • Avg $604 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 8h 11m (one-way)
Insights
Insights
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Booking Insights
Flight Deals

Cheap Flights from Panama City to St. Louis (PTY-STL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to St. Louis

Wed, Oct 14 - Sun, Oct 18
United Airlines Logo
9:45 am - 9:09 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
11h 24m1 stop Newark
United Airlines Logo
5:36 pm - 2:14 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
20h 38m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$723United Airlines
Wed, Oct 14 - Sun, Oct 18
United Airlines Logo
3:30 pm - 10:48 amPTY  Panama City Tocumen Intl-STL Lambert-St Louis
19h 18m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
5:36 pm - 2:14 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
20h 38m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$723United Airlines
Wed, Oct 14 - Sun, Oct 18
United Airlines Logo
3:30 pm - 8:16 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
28h 46m1 stop Houston George Bush Intcntl
United Airlines Logo
4:50 pm - 7:31 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
26h 41m1 stop Newark
$740United Airlines
Sun, Sep 6 - Thu, Sep 10
JetBlue Logo
2:20 pm - 11:31 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
9h 11m1 stop Atlanta Hartsfield-Jackson
JetBlue Logo
6:00 am - 12:58 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
6h 58m1 stop Atlanta Hartsfield-Jackson
$815JetBlue
Fri, Jan 8 - Fri, Jan 15
American Airlines Logo
4:46 pm - 10:51 amPTY  Panama City Tocumen Intl-STL Lambert-St Louis
19h 05m2 stops Miami Chicago O'Hare Intl
American Airlines Logo
4:57 pm - 3:38 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
21h 41m2 stops Dallas/Fort Worth Miami
$958American Airlines
Fri, Jan 8 - Fri, Jan 15
Copa Airlines Logo
8:08 am - 7:29 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
12h 21m1 stop Chicago O'Hare Intl
Copa Airlines Logo
7:04 pm - 2:01 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
17h 57m1 stop Chicago O'Hare Intl
$1,041Copa Airlines
Fri, Jan 8 - Fri, Jan 15
American Airlines Logo
4:46 pm - 11:59 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
8h 13m1 stop Miami
American Airlines Logo
4:57 pm - 3:38 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
21h 41m2 stops Dallas/Fort Worth Miami
$1,047American Airlines
Fri, Jan 8 - Fri, Jan 15
Multiple Airlines Logo
10:05 am - 3:26 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
30h 21m3 stops Bogotá El Dorado Mexico City Benito Juarez Toronto Pearson Intl
Multiple Airlines Logo
4:05 pm - 9:10 amSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
16h 05m2 stops Toronto Pearson Intl Bogotá El Dorado
$1,384Multiple Airlines
Fri, Jan 8 - Fri, Jan 15
Multiple Airlines Logo
10:05 am - 3:26 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
30h 21m3 stops Bogotá El Dorado Mexico City Benito Juarez Toronto Pearson Intl
Multiple Airlines Logo
4:05 pm - 1:20 amSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
32h 15m3 stops Toronto Pearson Intl Cancun Bogotá El Dorado
$1,431Multiple Airlines
Booking Insights

Price, demand and travel trends for Panama City to St. Louis flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Panama City to St. Louis with more confidence.

How much is a round-trip flight from Panama City to St. Louis?

Round-trip flights from Panama City to St. Louis start at $723. Prices are typical for this route right now, with typical round-trip fares ranging from $559 to $781. The lowest price found in the past 5 days was $723 on United Airlines.

What's the cheapest day of the week to fly from Panama City to St. Louis?

Thursday is the cheapest day of the week to fly from Panama City to St. Louis, it is 24% cheaper than the average day. Sunday is the most expensive day with flight prices 22% higher than average. Based on deals found by KAYAK users in the last 12 months.

Find deals

Key details for Panama City to St. Louis flights

Low season

August

Cheapest flight

$409
Best time to beat the crowds but there is an average 10% increase in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Panama City to St. Louis

When to book flights from Panama City to St. Louis

Are your dates flexible? Find out the best times to travel from Panama City to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Panama City to St. Louis flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Panama City to St. Louis?

    Flights from Panama City to St. Louis usually depart from Panama City Tocumen Intl (PTY) and arrive at Lambert-St Louis (STL).

  • What cabin classes can I book on flights from Panama City to St. Louis?

    Only Economy Class is available on flights from Panama City to St. Louis.

  • Which airports do connecting flights from Panama City to St. Louis pass through?

    One-stop flights from Panama City to St. Louis most commonly connect through:

    • Houston George Bush Intcntl (IAH) - 57% of one-stop connections
    • Miami (MIA) - 25% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 18% of one-stop connections

    Houston George Bush Intcntl (IAH) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Panama City to St. Louis?

    Yes. Being flexible with your travel dates can save you up to 38% on the Panama City to St. Louis route. Thursday is the cheapest departure day at $515 round-trip on average, while Sunday is the most expensive at $824, a difference of $309. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in St. Louis?

    Some of the most popular sights in St. Louis are Downtown St. Louis, Busch Stadium and Enterprise Center. These are among the most viewed places in St. Louis on KAYAK.

  • How long is a flight from Panama City to St. Louis?

    A nonstop flight from Panama City to St. Louis takes 0h 00m, covering 2,159 miles.

  • Do I need a passport to fly from Panama City to St. Louis?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Panama City to St. Louis changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $723 to $1,431. That means the highest observed fare was about 97% higher than the lowest one.

  • How are flight prices from Panama City to St. Louis looking right now?

    One-way fares from Panama City to St. Louis are currently in line with typical prices for this route. Average one-way fares are about $430.

  • How much time can I save by choosing a different layover airport from Panama City to St. Louis?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 8h 11m, compared with 8h 18m via Miami (MIA) and 8h 49m via Houston George Bush Intcntl (IAH).

  • What car rental options are available at Lambert-St Louis Airport (STL)?

    Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates starting from around $31 for economy cars. Top options include:
    · Hertz
    · Budget
    · Alamo
    · Enterprise Rent-A-Car
    · Payless

  • How much should I expect to pay for a Panama City to St. Louis flight?

    Round-trip flights from Panama City to St. Louis range from $559 to $781, with an average of $674 over the past 12 months. Anything below $559 counts as a good deal.

Your guide to booking Panama City to St. Louis flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Thursday departure instead of Sunday. On this route, Thursday flights average $515 - about $309 less than Sunday (38% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Panama City to St. Louis trip for October. Fares historically average $558 round-trip in that month - typically $418 less than the most expensive month, which is June (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Lambert-St Louis Airport.
    - MainStay Suites St. Louis Airport
    - Renaissance St. Louis Airport Hotel
    - Drury Inn & Suites St. Louis Airport

Everything you need to know for your flight from Panama City to St. Louis

Information on your arrival and departure airports

Panama City (PTY)
St. Louis (STL)