PTY - STL

$414 Find Cheap Flights from Panama City to St. Louis - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$611
Typical prices: $559-$781
JetBlue
Mon 10/22Thu 10/25
PTY - STL • 1 stop
Cheapest one-way
$414
Typical prices: $388-$529
American Airlines
Tue 12/18
PTY - STL • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Panama City and St. Louis. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
October
Cheapest • 17% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Miami (MIA)
Cheapest • Avg $604 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 8h 11m (one-way)
Insights
Insights
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We hope you love your trip to St. Louis!
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Booking Insights
Flight Deals

Cheap Flights from Panama City to St. Louis (PTY-STL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to St. Louis

Thu, Oct 22 - Sun, Oct 25
JetBlue Logo
2:24 pm - 11:54 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
9h 30m1 stop Atlanta Hartsfield-Jackson
JetBlue Logo
7:20 pm - 12:59 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
17h 39m1 stop Atlanta Hartsfield-Jackson
$611JetBlue
Sat, Oct 31 - Sat, Nov 7
JetBlue Logo
2:24 pm - 10:17 amPTY  Panama City Tocumen Intl-STL Lambert-St Louis
19h 53m1 stop Atlanta Hartsfield-Jackson
JetBlue Logo
6:00 am - 1:59 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
6h 59m1 stop Atlanta Hartsfield-Jackson
$673JetBlue
Sun, Sep 6 - Thu, Sep 10
JetBlue Logo
2:20 pm - 11:31 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
9h 11m1 stop Atlanta Hartsfield-Jackson
JetBlue Logo
6:00 am - 12:58 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
6h 58m1 stop Atlanta Hartsfield-Jackson
$689JetBlue
Tue, Oct 13 - Sun, Oct 25
United Airlines Logo
10:00 am - 12:13 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
26h 13m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
6:50 pm - 1:45 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
18h 55m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$709United Airlines
Thu, Oct 15 - Sun, Oct 25
United Airlines Logo
3:30 pm - 12:13 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
20h 43m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
6:50 pm - 1:45 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
18h 55m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$709United Airlines
Mon, Oct 12 - Tue, Oct 27
Delta Logo
2:24 pm - 11:54 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
9h 30m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:20 pm - 12:59 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
17h 39m1 stop Atlanta Hartsfield-Jackson
$709Delta
Mon, Oct 12 - Sun, Oct 25
Delta Logo
2:24 pm - 4:28 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
26h 04m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:20 pm - 12:59 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
17h 39m1 stop Atlanta Hartsfield-Jackson
$709Delta
Thu, Oct 15 - Tue, Oct 27
United Airlines Logo
3:30 pm - 12:13 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
20h 43m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
9:59 am - 7:02 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
9h 03m1 stop Newark
$709United Airlines
Tue, Oct 13 - Mon, Oct 26
United Airlines Logo
9:45 am - 9:09 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
11h 24m1 stop Newark
United Airlines Logo
7:30 am - 7:02 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
11h 32m2 stops Chicago O'Hare Intl Newark
$709United Airlines
Wed, Oct 14 - Mon, Oct 26
United Airlines Logo
3:30 pm - 12:13 pmPTY  Panama City Tocumen Intl-STL Lambert-St Louis
20h 43m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
United Airlines Logo
9:59 am - 7:02 pmSTL  Lambert-St Louis-PTY Panama City Tocumen Intl
9h 03m1 stop Newark
$709United Airlines
Booking Insights

Price, demand and travel trends for Panama City to St. Louis flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Panama City to St. Louis with more confidence.

How much is a round-trip flight from Panama City to St. Louis?

Round-trip flights from Panama City to St. Louis start at $611. Prices are typical for this route right now, with typical round-trip fares ranging from $559 to $781. The lowest price found in the past 5 days was $611 on JetBlue.

What's the cheapest day of the week to fly from Panama City to St. Louis?

Thursday is the cheapest day of the week to fly from Panama City to St. Louis, it is 24% cheaper than the average day. Sunday is the most expensive day with flight prices 22% higher than average. Based on deals found by KAYAK users in the last 12 months.

Find deals

Key details for Panama City to St. Louis flights

Low season

August

Cheapest flight

$414
Best time to beat the crowds but there is an average 10% increase in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Panama City to St. Louis

When to book flights from Panama City to St. Louis

Are your dates flexible? Find out the best times to travel from Panama City to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Panama City to St. Louis flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Panama City to St. Louis?

    Flights from Panama City to St. Louis usually depart from Panama City Tocumen Intl (PTY) and arrive at Lambert-St Louis (STL).

  • What cabin classes can I book on flights from Panama City to St. Louis?

    Only Economy Class is available on flights from Panama City to St. Louis.

  • Which airports do connecting flights from Panama City to St. Louis pass through?

    One-stop flights from Panama City to St. Louis most commonly connect through:

    • Houston George Bush Intcntl (IAH) - 57% of one-stop connections
    • Miami (MIA) - 25% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 18% of one-stop connections

    Houston George Bush Intcntl (IAH) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Panama City to St. Louis?

    Yes. Being flexible with your travel dates can save you up to 38% on the Panama City to St. Louis route. Thursday is the cheapest departure day at $515 round-trip on average, while Sunday is the most expensive at $824, a difference of $309. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in St. Louis?

    Some of the most popular sights in St. Louis are Downtown St. Louis, Busch Stadium and Enterprise Center. These are among the most viewed places in St. Louis on KAYAK.

  • How long is a flight from Panama City to St. Louis?

    A nonstop flight from Panama City to St. Louis takes 0h 00m, covering 2,159 miles.

  • What are the earliest and latest flights from Panama City to St. Louis?

    These are the earliest and latest flight times available from Panama City to St. Louis:

    • Earliest: departs at 12:00 am and lands at 12:00 am
    • Latest: departs at 12:00 am and lands at 12:00 am.

    The flight takes about 0h 00m.

  • Do I need a passport to fly from Panama City to St. Louis?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Panama City to St. Louis changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $611 to $4,656. That means the highest observed fare was about 8x higher than the lowest one.

  • How are flight prices from Panama City to St. Louis looking right now?

    One-way fares from Panama City to St. Louis are currently in line with typical prices for this route. Average one-way fares are about $438.

  • How much time can I save by choosing a different layover airport from Panama City to St. Louis?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 8h 11m, compared with 8h 18m via Miami (MIA) and 8h 49m via Houston George Bush Intcntl (IAH).

  • What car rental options are available at Lambert-St Louis Airport (STL)?

    Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates starting from around $31 for economy cars. Top options include:
    · Hertz
    · Budget
    · Alamo
    · Enterprise Rent-A-Car
    · Payless

  • How much should I expect to pay for a Panama City to St. Louis flight?

    Round-trip flights from Panama City to St. Louis range from $559 to $781, with an average of $674 over the past 12 months. Anything below $559 counts as a good deal.

Your guide to booking Panama City to St. Louis flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Thursday departure instead of Sunday. On this route, Thursday flights average $515 - about $309 less than Sunday (38% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Panama City to St. Louis trip for October. Fares historically average $558 round-trip in that month - typically $418 less than the most expensive month, which is June (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Lambert-St Louis Airport.
    - MainStay Suites St. Louis Airport
    - Renaissance St. Louis Airport Hotel
    - Drury Inn & Suites St. Louis Airport

Everything you need to know for your flight from Panama City to St. Louis

Information on your arrival and departure airports

Panama City (PTY)
St. Louis (STL)