PTY - STL

$317 Find Cheap Flights from Panama City to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to St. Louis departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to St. Louis, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$580
Overall average: $560
United Airlines
Mon 12/29Sat 1/10
PTY - STL • 1 stop
Cheapest one-way
$317
Typical prices: $340-$442
American Airlines
Thu 1/22
PTY - STL • 1 stop
When to travel
June
Cheapest • 33% price drop
August
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to St. Louis (PTY-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to St. Louis

Mon, Dec 29 - Sat, Jan 10
United Airlines Logo
4:41 pm - 9:55 pmPTY-STL
30h 14m1 stop
United Airlines Logo
4:42 pm - 5:07 pmSTL-PTY
23h 25m1 stop
$580United Airlines
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Tue, Dec 9 - Mon, Dec 15
United Airlines Logo
11:35 am - 10:04 amPTY-STL
23h 29m1 stop
United Airlines Logo
6:15 am - 5:07 pmSTL-PTY
9h 52m1 stop
$601United Airlines
Find Deal
Mon, Dec 29 - Sat, Jan 10
American Airlines Logo
2:53 pm - 10:35 pmPTY-STL
8h 42m1 stop
American Airlines Logo
5:07 pm - 1:27 pmSTL-PTY
19h 20m1 stop
$623American Airlines
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Mon, Dec 29 - Sat, Jan 10
American Airlines Logo
2:53 pm - 10:50 amPTY-STL
20h 57m2 stops
American Airlines Logo
5:04 pm - 1:27 pmSTL-PTY
19h 23m2 stops
$628American Airlines
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Thu, Dec 4 - Mon, Dec 8
United Airlines Logo
8:55 am - 9:58 pmPTY-STL
14h 03m1 stop
United Airlines Logo
6:15 am - 2:45 pmSTL-PTY
7h 30m1 stop
$638United Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 8
United Airlines Logo
11:35 am - 10:45 pmPTY-STL
12h 10m2 stops
United Airlines Logo
6:30 am - 7:38 pmSTL-PTY
12h 08m2 stops
$643United Airlines
Find Deal
Fri, Dec 5 - Tue, Dec 9
United Airlines Logo
8:55 am - 4:04 pmPTY-STL
8h 09m1 stop
United Airlines Logo
6:15 am - 2:45 pmSTL-PTY
7h 30m1 stop
$650United Airlines
Find Deal
Mon, Jan 5 - Sun, Jan 11
American Airlines Logo
2:53 pm - 9:08 amPTY-STL
19h 15m1 stop
American Airlines Logo
5:20 pm - 1:27 pmSTL-PTY
19h 07m2 stops
$717American Airlines
Find Deal
Mon, Jan 5 - Sun, Jan 11
American Airlines Logo
2:53 pm - 9:08 amPTY-STL
19h 15m1 stop
American Airlines Logo
5:05 am - 1:27 pmSTL-PTY
7h 22m1 stop
$828American Airlines
Find Deal
Mon, Jan 5 - Sun, Jan 11
American Airlines Logo
2:53 pm - 10:20 amPTY-STL
20h 27m2 stops
American Airlines Logo
3:54 pm - 1:27 pmSTL-PTY
20h 33m2 stops
$891American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Panama City to St. Louis flights

Get data-powered insights and trends into flights from Panama City to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to St. Louis?

The average price of all round-trip flights from Panama City to St. Louis clicked on KAYAK for each day over the last 12 months.

When flying from Panama City to St. Louis, you should consider leaving on a Thursday and avoid Wednesdays if you are looking for the best rates. For your return to Panama City, you’ll find the best rates on Tuesdays and the most expensive ones on Sundays.

What is the cheapest month to fly from Panama City to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to St. Louis is June, where tickets cost $362 (return) on average. On the other hand, the most expensive months are July and January, where the average cost of round-trip tickets is $659 and $624 respectively.

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Good to know

Low seasonApril
Cheapest flight$317
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 3% increase in price.
Flight from Panama City to St. Louis

When to book flights from Panama City to St. Louis

Are your dates flexible? Find out the best times to travel from Panama City to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to St. Louis

  • What is the cheapest flight from Panama City to St. Louis?

    In the last 3 days, the lowest price for a flight from Panama City to St. Louis was $317 for a one-way ticket and $580 for a round-trip.

  • Do I need a passport to fly between Panama City and St. Louis?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Panama City and on arrival in St. Louis.

  • Which airports will I be using when flying from Panama City to St. Louis?

    On your way to St. Louis, you’ll fly out from Panama City Tocumen Intl. You’ll be landing at Lambert-St Louis.

  • Which aircraft models fly most regularly from Panama City to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to St. Louis?

    Star Alliance is the only airline alliance operating flights between Panama City and St. Louis.

  • How does KAYAK find such low prices on flights from Panama City to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Panama City with another airline. Booking your flights between Panama City and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Panama City to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9044 reviews
6.6Food
8.1Crew
7.1Entertainment
7.3Comfort
7.7Boarding
Airline reviews

Quick and seamless boarding. No entertainment but fast Starlink wifi for this short trip and the staff was really friendly.

8.0 ExcellentTommy, Nov 2025YYZ - EWR
Read more United Airlines reviews

Quick and seamless boarding. No entertainment but fast Starlink wifi for this short trip and the staff was really friendly.

We boarded late. The crew at the airport was dismissive. The seat cushion on the plane was uncomfortable.

Very thoughtful flight attendant offered me water immediately since I had run to make my connection.

Door to door, the crew and staff were amazing. It was a stressful travel day with delays, but they were focused on customers and doing what they could to get us to our destinations.

I dread trans-Pacific flights. They are very long. This was my first time on Universal, and it was my best crossing ever. The staff were professional, the hospitality was great, and the food was delicious. The entertainment system filled the long flight hours. I will seek out Universal flights from now onwards. 🙂

United has come a long way, it’s been a fantastic experience traveling with them.

Even though we were delayed, we were able to make our connection

Starlink wifi on the Embraer E175 is an excellent experience. I was able to connect and work from IAD all the way to approach into BTV.

Great crew, excellent landing, good food. Over all great experience. Thank you!

Older aircraft, no meal, only food was for purchase. Not impressed United.

Everything you need to know for your flight from Panama City to St. Louis

Information on your arrival and departure airports

Panama City (PTY)
St. Louis (STL)