STL - SNA

$90 Find Cheap Flights from St. Louis to John Wayne (Santa Ana) - Compare and Save

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Everything you should know

Cheapest round-trip
$147
Typical prices: $399-$667
Frontier
Sun 12/23Mon 12/31
STL - SNA • 1 stop
Cheapest one-way
$90
Typical prices: $173-$321
Frontier
Tue 2/6
STL - SNA • 1 stop
Nonstop flights
Not available
There are currently no direct flights between St. Louis and Santa Ana. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 27% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Salt Lake City (SLC)
Cheapest • Avg $372 (round-trip)
Phoenix Sky Harbor Intl (PHX)
Shortest trip • 5h 41m (one-way)
Insights
Insights
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We hope you love your trip to Santa Ana!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from St. Louis to Santa Ana (STL-SNA)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santa Ana

Wed, Dec 23 - Thu, Dec 31
Frontier Logo
4:21 pm - 12:04 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
21h 43m1 stop Denver Intl
Frontier Logo
12:59 pm - 3:26 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
24h 27m1 stop Denver Intl
$147Frontier
Mon, Dec 21 - Thu, Dec 31
Frontier Logo
4:21 pm - 10:58 amSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
20h 37m2 stops Denver Intl Phoenix Sky Harbor Intl
Frontier Logo
12:59 pm - 3:26 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
24h 27m1 stop Denver Intl
$182Frontier
Thu, Nov 26 - Thu, Dec 3
Frontier Logo
9:09 am - 4:44 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
9h 35m1 stop Dallas/Fort Worth
Frontier Logo
12:08 pm - 10:57 amSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
20h 49m1 stop Denver Intl
$183Frontier
Sat, Dec 12 - Tue, Dec 15
Southwest Logo
8:45 am - 1:10 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
6h 25m1 stop Las Vegas Harry Reid Intl
Southwest Logo
10:00 am - 5:25 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
5h 25m1 stop Phoenix Sky Harbor Intl
$343Southwest
Tue, Nov 24 - Tue, Nov 24
American Airlines Logo
5:00 am - 11:10 amSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
8h 10m1 stop Dallas/Fort Worth
American Airlines Logo
3:28 pm - 12:01 amSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
6h 33m1 stop Chicago O'Hare Intl
$343American Airlines
Thu, Dec 3 - Sat, Dec 5
United Airlines Logo
2:50 pm - 9:09 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
8h 19m1 stop Denver Intl
United Airlines Logo
10:20 am - 7:26 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
7h 06m1 stop Chicago O'Hare Intl
$343United Airlines
Sat, Dec 12 - Tue, Dec 15
Southwest Logo
10:35 am - 6:20 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
9h 45m2 stops Kansas City Dallas Love Field
Southwest Logo
8:50 am - 5:25 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
6h 35m2 stops Phoenix Sky Harbor Intl Omaha Eppley Airfield
$353Southwest
Wed, Nov 25 - Fri, Nov 27
United Airlines Logo
1:40 pm - 5:33 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
5h 53m1 stop Denver Intl
United Airlines Logo
7:00 am - 6:05 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
9h 05m1 stop San Francisco
$363United Airlines
Tue, Jan 5 - Sat, Jan 9
American Airlines Logo
2:45 pm - 6:35 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
5h 50m1 stop Phoenix Sky Harbor Intl
American Airlines Logo
11:32 am - 10:31 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
8h 59m1 stop Chicago O'Hare Intl
$399American Airlines
Fri, Jan 15 - Mon, Jan 18
American Airlines Logo
5:29 am - 11:08 amSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
7h 39m1 stop Dallas/Fort Worth
American Airlines Logo
3:36 pm - 11:57 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
6h 21m1 stop Chicago O'Hare Intl
$399American Airlines
Booking Insights

Price, demand and travel trends for St. Louis to Santa Ana flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from St. Louis to Santa Ana?

Round-trip flights from St. Louis to Santa Ana typically range from $399 to $667. The lowest price found in the past 5 days was $147, on Frontier.

What's the cheapest day of the week to fly from St. Louis to Santa Ana?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from St. Louis to Santa Ana. It’s 24% cheaper than the average day, while Monday is the most expensive, with prices 52% higher.

What’s the cheapest month to fly from St. Louis to Santa Ana?

•February is the cheapest month to fly from St. Louis to Santa Ana at $379 round-trip.
•May ($790) and July ($626) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 108% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for St. Louis to Santa Ana flights

Low season

November

Cheapest flight

$90
Beat the crowds with an average 33% drop in travelers.
The most popular month to fly with an average 55% increase in travelers.
One-way flight from St. Louis to Santa Ana

When to book flights from St. Louis to Santa Ana

Are your dates flexible? Find out the best times to travel from St. Louis to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your St. Louis to Santa Ana flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from St. Louis to Santa Ana?

    Two cabin classes are available on flights from St. Louis to Santa Ana:

    • Economy Class
    • First Class

  • How long is a flight from St. Louis to Santa Ana?

    A nonstop flight from St. Louis to Santa Ana takes 00m, covering 1,565 miles.

  • Do I need a passport to fly from St. Louis to Santa Ana?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a St. Louis to Santa Ana flight?

    Round-trip flights from St. Louis to Santa Ana range from $399 to $667, with an average of $518 over the past 12 months. Anything below $399 counts as a good deal.

  • How are flight prices from St. Louis to Santa Ana looking right now?

    One-way fares from St. Louis to Santa Ana are currently lower than usual. Average one-way flight prices are about $189, which is 17% below the typical average for this route.

  • What car rental options are available at Santa Ana J. Wayne/Orange Cnty Airport (SNA)?

    Santa Ana J. Wayne/Orange Cnty Airport (SNA) hosts 5 major car rental companies, with daily rates averaging $58 for economy cars. Top options include:

    • Dollar
    • Thrifty
    • Hertz
    • Budget
    • Alamo

  • Which airports can I use when flying from St. Louis to Santa Ana?

    Flights from St. Louis to Santa Ana usually depart from Lambert-St Louis (STL) and arrive at Santa Ana J. Wayne/Orange Cnty (SNA).

  • Which airports do connecting flights from St. Louis to Santa Ana pass through?

    One-stop flights from St. Louis to Santa Ana most commonly connect through:

    • Phoenix Sky Harbor Intl (PHX) - 50% of one-stop connections
    • Denver Intl (DEN) - 16% of one-stop connections
    • Dallas/Fort Worth (DFW) - 16% of one-stop connections
    • Las Vegas Harry Reid Intl (LAS) - 12% of one-stop connections

  • Can I save money by using flexible dates for flights from St. Louis to Santa Ana?

    Yes. Flexible dates can save you up to 50% on flights from St. Louis to Santa Ana. Wednesday is the cheapest departure day at $396 round-trip on average, while Monday is the most expensive at $790, a difference of $394.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from St. Louis to Santa Ana?

    Flying via Salt Lake City (SLC) gives the shortest average 1-stop total travel time at 5h 38m, compared with 5h 41m via Phoenix Sky Harbor Intl (PHX) and 6h 24m via Dallas/Fort Worth (DFW).

  • What is the time difference between St. Louis and Santa Ana?

    Santa Ana is 2 hours behind St. Louis (Pacific Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santa Ana?

    Some of the most popular sights in Santa Ana are Embassy Suites by Hilton Santa Ana Orange County Airport, Santa Ana Zoo and Old Orange County Courthouse. These are among the most viewed places in Santa Ana on KAYAK.

Your guide to booking St. Louis to Santa Ana flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Monday. On this route, Wednesday flights average $396, about $394 less than Monday fares (50% savings) based on the last 12 months.
  • If you can choose when to travel, plan your St. Louis to Santa Ana trip for February. Fares historically average $379 round-trip in that month - typically $411 less than the most expensive month, which is May (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santa Ana J. Wayne/Orange Cnty Airport.

    • voco Orange County - Airport by IHG
    • Hotel Zessa Orange County Airport, a DoubleTree by Hilton
    • Courtyard by Marriott Santa Ana Orange County

More options for your flight from St. Louis to Santa Ana

Complete your trip to Santa Ana with a hotel stay or car rental

Car rentals in Santa Ana
Hotels in Santa Ana
Vacations in Santa Ana