STL - SNA

$113 Find Cheap Flights from St. Louis to Santa Ana

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from St. Louis to Santa Ana departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Ana

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santa Ana, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from St. Louis to Santa Ana, as well as popular online travel agencies
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Flights Deals

Cheap Flights from St. Louis to Santa Ana (STL-SNA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from St. Louis to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from St. Louis to Santa Ana

Thu, Sep 25 - Sat, Sep 27
Spirit Airlines Logo
12:05 pm - 11:35 amSTL-SNA
25h 30m1 stop
Spirit Airlines Logo
12:32 pm - 10:50 amSNA-STL
20h 18m1 stop
$219Spirit Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
Frontier Logo
7:54 pm - 11:27 amSTL-SNA
17h 33m1 stop
Frontier Logo
12:58 pm - 9:06 amSNA-STL
18h 08m1 stop
$225Frontier
Find Deal
Thu, Aug 28 - Tue, Sep 2
American Airlines Logo
7:01 am - 11:38 amSTL-SNA
6h 37m1 stop
American Airlines Logo
10:38 am - 10:17 pmSNA-STL
9h 39m1 stop
$267American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
7:53 am - 11:57 amSTL-SNA
6h 04m1 stop
American Airlines Logo
12:50 pm - 10:50 pmSNA-STL
8h 00m2 stops
$272American Airlines
Find Deal
Sun, Nov 2 - Sat, Nov 8
Southwest Logo
5:20 am - 10:50 amSTL-SNA
7h 30m1 stop
Southwest Logo
7:30 am - 5:00 pmSNA-STL
7h 30m2 stops
$277Southwest
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Tue, Aug 19 - Sat, Aug 23
United Airlines Logo
5:15 am - 9:16 amSTL-SNA
6h 01m1 stop
United Airlines Logo
10:30 am - 9:32 pmSNA-STL
9h 02m1 stop
$279United Airlines
Find Deal
Tue, Sep 2 - Fri, Sep 5
Southwest Logo
4:35 pm - 9:10 pmSTL-SNA
6h 35m1 stop
Southwest Logo
6:45 am - 6:35 pmSNA-STL
9h 50m2 stops
$282Southwest
Find Deal
Wed, Nov 5 - Mon, Nov 10
Delta Logo
2:29 pm - 10:17 pmSTL-SNA
9h 48m2 stops
Delta Logo
5:05 pm - 12:37 amSNA-STL
5h 32m1 stop
$315Delta
Find Deal
Thu, Aug 28 - Tue, Sep 2
Delta Logo
6:45 pm - 10:23 pmSTL-SNA
5h 38m1 stop
Delta Logo
6:55 pm - 8:36 amSNA-STL
11h 41m2 stops
$325Delta
Find Deal
Tue, Sep 23 - Sat, Sep 27
United Airlines Logo
11:05 am - 8:28 pmSTL-SNA
11h 23m2 stops
United Airlines Logo
11:32 am - 10:35 pmSNA-STL
9h 03m2 stops
$367United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for St. Louis to Santa Ana flights

Get data-powered insights and trends into flights from St. Louis to Santa Ana to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from St. Louis to John Wayne (Santa Ana)?

The average price of all round-trip flights from St. Louis to Santa Ana clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to John Wayne (Santa Ana) on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from St. Louis to John Wayne (Santa Ana). For your return ticket, we recommend flying on a Tuesday and avoiding Saturdays for the best deals.

What is the cheapest month to fly from St. Louis to Santa Ana?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from St. Louis to Santa Ana, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from St. Louis to Santa Ana is April, where tickets cost $366 (return) on average. On the other hand, the most expensive months are June and December, where the average cost of round-trip tickets is $499 and $461 respectively.

How far in advance should I book a flight from St. Louis to Santa Ana?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from St. Louis to Santa Ana, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from St. Louis to Santa Ana, you should book around 2 weeks before departure, which saves you about 37% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 9 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$113
Best time to beat the crowds with an average 15% drop in price.
Most popular time to fly with an average 1% increase in price.
Flight from St. Louis to John Wayne (Santa Ana)

When to book flights from St. Louis to Santa Ana

Are your dates flexible? Find out the best times to travel from St. Louis to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from St. Louis to John Wayne (Santa Ana)

  • What is the cheapest flight from St. Louis to Santa Ana?

    In the last 3 days, the lowest price for a flight from St. Louis to Santa Ana was $113 for a one-way ticket and $219 for a round-trip.

  • Do I need a passport to fly between St. Louis and John Wayne (Santa Ana)?

    No

  • Which aircraft models fly most regularly from St. Louis to John Wayne (Santa Ana)?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from St. Louis to John Wayne (Santa Ana)?

    oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between St. Louis and John Wayne (Santa Ana), with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from St. Louis to Santa Ana, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from St. Louis to Santa Ana are Southwest and Delta. With an average price for the route of $452 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $371 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from St. Louis to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from St. Louis to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from St. Louis to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from St. Louis to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to St. Louis with another airline. Booking your flights between St. Louis and SNA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from St. Louis to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from St. Louis to Santa Ana

 
See real verified KAYAK customer reviews for airlines flying from St. Louis to Santa Ana. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from St. Louis to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4241 reviews
8.6Crew
7.0Food
8.1Boarding
8.0Comfort
7.5Entertainment
Airline reviews

Very smooth checking in our luggage with a super pleasant SW agent. I enjoyed a fun entertaining movie.

10.0 ExcellentGordon, Jul 2025GEG - OAK
Read more Southwest reviews

Very smooth checking in our luggage with a super pleasant SW agent. I enjoyed a fun entertaining movie.

First time traveling on Southwest since bag fees were implemented. Usual good service. Just more expensive now.

It was a perfect flight in all aspects! Both legs!

Boarding process, crew were good. But the seats were so uncomfortable that was all I could focus on. I literally had to sit forward so that all 3 of us could fit in row. I will try to avoid Southwest in the future for any flights over 60 minutes.

Great flight, 47 passengers on a 180 seat plane. Stewardess was pleasant and cheerful.

Great experience flying Southwest. The crew was really kind and helpful, and very friendly with our toddler.

Very good. Sad to learn Southwest is going start to charge for bags

Plane late from DC to Austin 30 minutes. Crew made up much of the time enroute to San Diego.

Fine, but how to board on SW versus othrr airlines, is just lame. Goood staff though and all was solid otherwise.

Exceptional crew! Friendly and professional. Pleasant attitude and treated everyone with respect.

Food was surprisingly good but the WiFi was not great

My flight was extremely cold. I had a jacket and a cover was left in each seat. The cover was extremely thin and I have a disability, fibromyalgia and arthrithis and AC air is the worst. I closed my vent and my husbands vent and it still was frigid. I asked the attendant if I could get another cover and she quickly almost dismissively and totally unconcerned stating, (I quote) (one per chair) and walked off so quickly that I didn't get a chance to explain to her that I literally have adisability. I didnt want to make a seen so I set on that flight for over 5 hours in pain, joints locking up and extremely uncomfortable. When my fibromyalgia flares up my joints not only ache but they will lock up also and it takes me days to get back to my regular self even though I take medication for it. I felt like it would not have hurt anyone at all for her to just give me an extra cover because I'm sure they have all types of medical issues in people that fly every day.

My flight was canceled after being rescheduled for four days canceling my trip. Kayak and everyone affiliated with it I.e the airlines, and just fly have been excruciating to deal with. My trip to visit family had to be canceled as there was no way to make it. I am furious at all of you.

They delayed our flight because of bad weather in NY which was completely understandable. Then they cancelled our flight and a later flight that evening. The earliest we could fly was the next morning. We ended up buying last minute tickets on another airline and made it home slightly delayed but safely that evening. Delta kept saying it was weather related but if that was the case how did we make it back on another airline? The weather in NY was cloudy but not bad.

Not a "Delta" issue, but a JFK issue: We booked a connecting flight with 3 1/2 hours between to clearn immigration and customs. Our inbound flight (BCN to JFK) was on the taxiway 45 minutes which ate into our layover time. Immigtration was insanely quick with the CBP MPC app; however, clearing TSA (again, after we were ALREADY cleared in Spain on the inbound international flight) took over 95 minutes. This left us with 10 minutes before boarding the connecting flight (JFK to SAN) to walk to the far end of Terminal 4 and try to find food. We didn't find any food that could promise to serve us in under 10 minutes so we boarded the Delta flight after coming off a plance and an 8-hour flight knowing that we wouldn't be served any food on the next 5 1/2 hour flight. I feel like Delta needs to put pressure on the JFK TSA to open more screening stations (by our count, we saw only 5 scanners open and a line of - as we said - over 90 minutes. The insult is that we WERE ALREADY SCREENED through TSA, but as you come off one flight into the USA, you have to go through the whole process again. It seems like if you have a connecting flight, there should be a way to pass through immigration and customs without needing to return through TSA.

There are 4 flights in consecutive gates with about the same departure time. Two flights were boarding at the same time. One was delayed or boarding would be happening at the same time. I am not sure what Delta and LAX need to do to have a better layout at the end of Terminal 2

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

The entertainment and wifi mostly didn't work on this flight.

Terrible entertainment system - kept freezing and audio kept cutting out. Snacks were mediocre at best for a 5 hour flight.

I am still upset that my bag was lost on a recent trip to Rome ; we were inconvenienced and out €150 Euros ; delta has refused to reimburse us

Overall a very poor experience - booked premium economy tickets but due to last minute flight delays , all my itinery went for a toss and had to fly economy class with no access to lounge or any compensation by united airlines to make up for the flight delays . i had expected better experience than that from united.

Boarded plane and then delayed 1.5 hours while on the plane

Horrific. They missed my connecting flight to San Diego. I didn’t get there until Monday at 9am when I had a mandatory court settlement conference scheduled at 6am since we had parties on the east coast. This caused many issues. All because United apparently forgot to hold the doors open until my flight landed that only had a 10 minute delay. This was the last flight to Southern California. So I couldn’t even rent a car to finish the trip. United cannot be trusted when traveling on specific days and times since weather didn’t have anything to do with the delays.

My flight was delayed a very short period of time but they did not hold my connecting flight to San Diego, also through United. So they closed the doors before we got off our plane. They would only have to help the door open for another five to ten minutes. So I missed a court deadline for a manditory mediation settlement conference for my client. I had to get an associate to be there in person and be on the phone with him relaying what he needs to do the entire time. The court was very upset with me and so was my client. United cannot be trusted.

We were given vouchers we couldn’t use with a 5.5 hour delay

Really good 😊 the woman at the gate entrance was a little rude checking in our carry-on but i dont think she worked for the airline, she worked for the airport at sacramento, other than that amazing.

Boarding was mayhem. Late boarding by 15 minutes because of lack of staff (missing 1 flight attendant. We had to wait for an arrival of another plane before we could board). Flight was a little rough, but cannot blame on airlines.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

United out of SFO is having issues with catering so none of our meals were loaded on the plane and no offer of compensation for our tickets purchased was offered.

A bit rush for transit. Food and entertainment are not available

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

Long 5 hour and 45 min flight and only one drink service and cookie snack

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

Two flight changes before the scheduled flight. On the day of the flight, the flight was delayed, which caused the connecting flight to be missed. Then, I was directed to another airport (CUN) and traveled to Tulum. American gave a $12 voucher for lunch. The least expensive item on the menu at a Mexican restaurant was $9.99. Driving to Tulum was a bad auto crash, and traffic was delayed two-plus hours. The bottom line is that we should have been at the hotel at noon, but it ended up at 11:30 PM.

Severe turbulence. Captain never came on to reassure passengers after things settled down.

My first flight was delayed 5 hours. The 2nd flight was canceled til the next day and the never even tried to compensate for it. Worse I was delayed again on the flight the rebooked me on.

Boarding in Orlando was not good. Giant mob at the gate, should have been lines.

Decent clean onboard experience. Okay discount airline experience. Unfortunately, any customer service interactions are difficult and unhelpful. There is no service. Also, a premium seat only gets you premium boarding if you line up first. Once they start general boarding you must go to the back of the line. Not very premium

baggage clamed had to wait over a hour and half for all people on my flight it was terrible

The ticketing agents were rude but then we had a great gate agent very nice we had to ride a buss out to where the plane was parked but it was in some back corner of the airport when we got to the plane the captain who was great btw was cleaning the plane because the same rude ticketing agent told them they we not contracted to vacuum the plane. The ride to las Vegas was fine We had a connecting flight to Dallas. The flight was fine but when we arrived in Dallas everyone who flew on any frontier airlines the picked up bags from baggage claim D15 had to wait over a hour for their bags to start we arrived at 11:30pm ish to the gate we didn't leave the baggage clamed till 12:50 am very not happy and i used to fly frontier 4 times a week for work in Denver i will not be using them again

I was 2 hr arrive in the airport and 45 min in the line . After take to my turn . The agent tell me I’m later . I can not board . So my vacation was going to the floor . Just for their bad customer service agent in the airline

Frontier Airlines was AWFUL. I was an hour early for my flight and the lady refused to check me in. I had to purchase a whole new ticket with a different airline.

My flight was canceled I was promised a reginf still not received.

Late, terrible communication, horrible planning of passenger seating until the literal last minute. One of the worst flying experiences of my life. Y'all suck

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