SNA - STL

$110 Find Cheap Flights from John Wayne (Santa Ana) to St. Louis - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$183
Typical prices: $427-$580
Frontier
Sun 1/7Tue 1/9
SNA - STL • 1 stop
Cheapest one-way
$110
Typical prices: $176-$382
Frontier
Mon 12/17
SNA - STL • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and St. Louis. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 38% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Salt Lake City (SLC)
Cheapest • Avg $528 (round-trip)
Phoenix Sky Harbor Intl (PHX)
Shortest trip • 5h 38m (one-way)
Insights
Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Ana to St. Louis (SNA-STL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to St. Louis

Thu, Jan 7 - Sat, Jan 9
Frontier Logo
11:13 am - 10:30 amSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
21h 17m1 stop Denver Intl
Frontier Logo
6:20 pm - 10:28 amSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
18h 08m1 stop Denver Intl
$183Frontier
Thu, Jan 7 - Sat, Jan 9
Frontier Logo
11:13 am - 10:30 amSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
21h 17m1 stop Denver Intl
Frontier Logo
6:20 pm - 3:48 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
23h 28m2 stops Denver Intl San Francisco
$199Frontier
Sat, Dec 12 - Mon, Dec 14
American Airlines Logo
10:47 am - 8:27 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
7h 40m1 stop Dallas/Fort Worth
American Airlines Logo
8:43 am - 2:04 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
7h 21m1 stop Dallas/Fort Worth
$343American Airlines
Sat, Dec 12 - Mon, Dec 14
United Airlines Logo
10:20 am - 9:29 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
9h 09m1 stop Chicago O'Hare Intl
United Airlines Logo
6:30 am - 11:37 amSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
7h 07m1 stop Chicago O'Hare Intl
$343United Airlines
Sat, Dec 12 - Mon, Dec 14
Southwest Logo
6:45 am - 4:20 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
7h 35m2 stops Las Vegas Harry Reid Intl Omaha Eppley Airfield
Southwest Logo
5:05 am - 8:55 amSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
5h 50m1 stop Las Vegas Harry Reid Intl
$348Southwest
Sat, Dec 12 - Mon, Dec 14
United Airlines Logo
6:50 am - 6:16 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
9h 26m2 stops Denver Intl Chicago O'Hare Intl
United Airlines Logo
8:40 am - 1:01 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
6h 21m1 stop Denver Intl
$348United Airlines
Sat, Dec 12 - Mon, Dec 14
Southwest Logo
6:45 am - 4:20 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
7h 35m2 stops Las Vegas Harry Reid Intl Omaha Eppley Airfield
Southwest Logo
12:40 pm - 7:20 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
8h 40m2 stops Kansas City Las Vegas Harry Reid Intl
$353Southwest
Wed, Dec 23 - Thu, Dec 31
American Airlines Logo
4:37 pm - 12:16 amSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
5h 39m1 stop Dallas/Fort Worth
American Airlines Logo
2:45 pm - 6:35 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
5h 50m1 stop Phoenix Sky Harbor Intl
$415American Airlines
Wed, Nov 11 - Mon, Nov 16
Delta Logo
9:53 am - 5:41 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
5h 48m1 stop Salt Lake City
Delta Logo
2:20 pm - 6:31 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
6h 11m1 stop Salt Lake City
$485Delta
Wed, Nov 11 - Mon, Nov 16
Delta Logo
9:53 am - 5:41 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
5h 48m1 stop Salt Lake City
Delta Logo
2:20 pm - 6:31 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
6h 11m1 stop Salt Lake City
$485Delta
Booking Insights

Price, demand and travel trends for Santa Ana to St. Louis flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Santa Ana to St. Louis?

Round-trip flights from Santa Ana to St. Louis typically range from $427 to $580. The lowest price found in the past 5 days was $183, on Frontier.

What's the cheapest day of the week to fly from Santa Ana to St. Louis?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Santa Ana to St. Louis. It’s 20% cheaper than the average day, while Monday is the most expensive, with prices 44% higher.

What’s the cheapest month to fly from Santa Ana to St. Louis?

•February is the cheapest month to fly from Santa Ana to St. Louis at $317 round-trip.
•August ($831) and January ($610) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 162% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Santa Ana to St. Louis flights

Low season

March

Cheapest flight

$110
Beat the crowds with an average 51% drop in travelers.
The most popular month to fly with an average 70% increase in travelers.
One-way flight from Santa Ana to St. Louis

When to book flights from Santa Ana to St. Louis

Are your dates flexible? Find out the best times to travel from Santa Ana to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santa Ana to St. Louis flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santa Ana to St. Louis?

    Three cabin classes are available on flights from Santa Ana to St. Louis:

    • Economy Class
    • Business Class
    • First Class

  • How long is a flight from Santa Ana to St. Louis?

    A nonstop flight from Santa Ana to St. Louis takes 00m, covering 1,565 miles.

  • Do I need a passport to fly from Santa Ana to St. Louis?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Santa Ana to St. Louis flight?

    Round-trip flights from Santa Ana to St. Louis range from $427 to $580, with an average of $508 over the past 12 months. Anything below $427 counts as a good deal.

  • How are flight prices from Santa Ana to St. Louis looking right now?

    One-way fares from Santa Ana to St. Louis are currently lower than usual. Average one-way flight prices are about $188, which is 25% below the typical average for this route.

  • What car rental options are available at Lambert-St Louis Airport (STL)?

    Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates averaging $78 for economy cars. Top options include:

    • Hertz
    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Payless

  • Which airports can I use when flying from Santa Ana to St. Louis?

    Flights from Santa Ana to St. Louis usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Lambert-St Louis (STL).

  • Which airports do connecting flights from Santa Ana to St. Louis pass through?

    One-stop flights from Santa Ana to St. Louis most commonly connect through:

    • Denver Intl (DEN) - 37% of one-stop connections
    • Phoenix Sky Harbor Intl (PHX) - 35% of one-stop connections
    • Las Vegas Harry Reid Intl (LAS) - 13% of one-stop connections
    • Dallas/Fort Worth (DFW) - 8% of one-stop connections

  • Can I save money by using flexible dates for flights from Santa Ana to St. Louis?

    Yes. Flexible dates can save you up to 45% on flights from Santa Ana to St. Louis. Wednesday is the cheapest departure day at $408 round-trip on average, while Monday is the most expensive at $734, a difference of $326.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Santa Ana to St. Louis?

    Flying via Phoenix Sky Harbor Intl (PHX) gives the shortest average 1-stop total travel time at 5h 38m, compared with 5h 49m via Salt Lake City (SLC) and 5h 52m via Denver Intl (DEN).

  • What is the time difference between Santa Ana and St. Louis?

    St. Louis is 2 hours ahead of Santa Ana (Central Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in St. Louis?

    Some of the most popular sights in St. Louis are Busch Stadium, Enterprise Center and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

Your guide to booking Santa Ana to St. Louis flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Monday. On this route, Wednesday flights average $408, about $326 less than Monday fares (44% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Santa Ana to St. Louis trip for February. Fares historically average $317 round-trip in that month - typically $514 less than the most expensive month, which is August (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Lambert-St Louis Airport.

    • Renaissance St. Louis Airport Hotel
    • Drury Inn & Suites St. Louis Airport
    • DoubleTree by Hilton St. Louis Airport

More options for your flight from Santa Ana to St. Louis

Complete your trip to St. Louis with a hotel stay or car rental

Car rentals in St. Louis
Hotels in St. Louis
Vacations in St. Louis