SNA - STL

$150 Find Cheap Flights from John Wayne (Santa Ana) to St. Louis - Compare and Save

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Everything you should know

Cheapest round-trip
$272
Typical prices: $372-$563
Frontier
Fri 10/26Mon 10/29
SNA - STL • 1 stop
Cheapest one-way
$140
Typical prices: $169-$387
Frontier
Mon 10/22
SNA - STL • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and St. Louis. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
October
Cheapest • 34% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Chicago O'Hare Intl (ORD)
Cheapest • Avg $345 (round-trip)
Phoenix Sky Harbor Intl (PHX)
Shortest trip • 5h 24m (one-way)
Insights
Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Ana to St. Louis (SNA-STL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to St. Louis

Mon, Oct 26 - Thu, Oct 29
Frontier Logo
11:38 am - 7:15 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
5h 37m1 stop Denver Intl
Frontier Logo
12:14 pm - 6:06 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
7h 52m1 stop Dallas/Fort Worth
$272Frontier
Thu, Nov 5 - Mon, Nov 9
Multiple Airlines Logo
7:30 am - 12:33 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
27h 03m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
1:28 pm - 7:11 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
7h 43m1 stop Las Vegas Harry Reid Intl
$279Multiple Airlines
Wed, Nov 18 - Thu, Nov 19
Southwest Logo
8:20 am - 6:35 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
8h 15m1 stop Denver Intl
Southwest Logo
5:55 am - 10:50 amSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
6h 55m1 stop Phoenix Sky Harbor Intl
$353Southwest
Thu, Nov 12 - Sat, Nov 14
Delta Logo
9:53 am - 5:41 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
5h 48m1 stop Salt Lake City
Delta Logo
5:00 pm - 10:02 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
7h 02m1 stop Salt Lake City
$353Delta
Thu, Nov 12 - Sat, Nov 14
Delta Logo
5:16 pm - 12:40 amSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
5h 24m1 stop Salt Lake City
Delta Logo
3:30 pm - 8:55 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
7h 25m1 stop Minneapolis St Paul
$353Delta
Thu, Oct 8 - Tue, Oct 13
American Airlines Logo
1:26 pm - 11:42 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
8h 16m1 stop Dallas/Fort Worth
American Airlines Logo
5:40 am - 12:36 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
8h 56m1 stop Dallas/Fort Worth
$370American Airlines
Fri, Nov 6 - Tue, Nov 10
Southwest Logo
12:55 pm - 10:25 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
7h 30m1 stop Denver Intl
Southwest Logo
6:25 am - 11:20 amSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
6h 55m1 stop Las Vegas Harry Reid Intl
$376Southwest
Tue, Nov 24 - Fri, Nov 27
American Airlines Logo
4:32 pm - 11:49 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
5h 17m1 stop Phoenix Sky Harbor Intl
American Airlines Logo
5:00 am - 10:01 amSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
7h 01m1 stop Dallas/Fort Worth
$376American Airlines
Wed, Nov 18 - Tue, Dec 1
United Airlines Logo
8:46 am - 9:40 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
10h 54m2 stops Denver Intl Chicago O'Hare Intl
United Airlines Logo
6:00 am - 2:01 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
10h 01m1 stop Houston George Bush Intcntl
$441United Airlines
Tue, Nov 17 - Tue, Dec 1
United Airlines Logo
8:46 am - 9:40 pmSNA  Santa Ana J. Wayne/Orange Cnty-STL Lambert-St Louis
10h 54m2 stops Denver Intl Chicago O'Hare Intl
United Airlines Logo
6:00 am - 2:01 pmSTL  Lambert-St Louis-SNA Santa Ana J. Wayne/Orange Cnty
10h 01m1 stop Houston George Bush Intcntl
$448United Airlines
Booking Insights

Price, demand and travel trends for Santa Ana to St. Louis flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Santa Ana to St. Louis with more confidence.

How much is a round-trip flight from Santa Ana to St. Louis?

Round-trip flights from Santa Ana to St. Louis start at $272. Prices are below average for this route right now, with typical round-trip fares ranging from $372 to $563. The lowest price found in the past 5 days was $272 on Frontier.

What's the cheapest day of the week to fly from Santa Ana to St. Louis?

Wednesday is the cheapest day of the week to fly from Santa Ana to St. Louis, it is 27% cheaper than the average day. Sunday is the most expensive day with flight prices 54% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Santa Ana to St. Louis?

•October is the cheapest month to fly from Santa Ana to St. Louis at $324 round-trip.
•January ($610) and July ($552) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 88% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Santa Ana to St. Louis flights

Low season

March

Cheapest flight

$140
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly with an average 10% increase in price.
Flight from Santa Ana to St. Louis

When to book flights from Santa Ana to St. Louis

Are your dates flexible? Find out the best times to travel from Santa Ana to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santa Ana to St. Louis flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Santa Ana to St. Louis?

    Flights from Santa Ana to St. Louis usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Lambert-St Louis (STL).

  • What cabin classes can I book on flights from Santa Ana to St. Louis?

    Three cabin classes are available on flights from Santa Ana to St. Louis:

    • Economy Class
    • Business Class
    • First Class

  • Which airports do connecting flights from Santa Ana to St. Louis pass through?

    One-stop flights from Santa Ana to St. Louis most commonly connect through:

    • Denver Intl (DEN) - 37% of one-stop connections
    • Phoenix Sky Harbor Intl (PHX) - 23% of one-stop connections
    • Las Vegas Harry Reid Intl (LAS) - 19% of one-stop connections
    • Dallas/Fort Worth (DFW) - 10% of one-stop connections

    Denver Intl (DEN) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Santa Ana to St. Louis?

    Yes. Being flexible with your travel dates can save you up to 53% on the Santa Ana to St. Louis route. Wednesday is the cheapest departure day at $361 round-trip on average, while Sunday is the most expensive at $759, a difference of $398. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in St. Louis?

    Some of the most popular sights in St. Louis are Busch Stadium, Enterprise Center and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

  • How long is a flight from Santa Ana to St. Louis?

    A nonstop flight from Santa Ana to St. Louis takes 0h 00m, covering 1,565 miles.

  • Do I need a passport to fly from Santa Ana to St. Louis?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • How are flight prices from Santa Ana to St. Louis looking right now?

    One-way fares from Santa Ana to St. Louis are currently lower than usual. Average one-way flight prices are about $191, which is 21% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Santa Ana to St. Louis?

    Flying via Phoenix Sky Harbor Intl (PHX) gives the shortest average 1-stop total travel time at 5h 24m, compared with 5h 52m via Salt Lake City (SLC) and 5h 53m via Las Vegas Harry Reid Intl (LAS).

  • What is the time difference between Santa Ana and St. Louis?

    St. Louis is 2 hours ahead of Santa Ana (Central Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Lambert-St Louis Airport (STL)?

    Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates starting from around $31 for economy cars. Top options include:
    • Hertz
    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Payless

  • How much should I expect to pay for a Santa Ana to St. Louis flight?

    Round-trip flights from Santa Ana to St. Louis range from $372 to $563, with an average of $492 over the past 12 months. Anything below $372 counts as a good deal.

Your guide to booking Santa Ana to St. Louis flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Wednesday departure instead of Sunday. On this route, Wednesday flights average $361 - about $398 less than Sunday (52% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Santa Ana to St. Louis trip for October. Fares historically average $324 round-trip in that month - typically $286 less than the most expensive month, which is January (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Lambert-St Louis Airport.
    - Drury Inn & Suites St. Louis Airport
    - Renaissance St. Louis Airport Hotel
    - DoubleTree by Hilton St. Louis Airport

More options for your flight from Santa Ana to St. Louis

Complete your trip to St. Louis with a hotel stay or car rental

Car rentals in St. Louis
Hotels in St. Louis
Vacations in St. Louis