SDF - DSM

$154 Find Cheap Flights from Louisville to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Louisville to Des Moines departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Louisville to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Louisville to Des Moines, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$338
Multiple Airlines
Wed 5/20Sat 5/23
SDF - DSM • 2 stops
Cheapest one-way
$154
Typical prices: $129-$216
Delta
Tue 5/26
SDF - DSM • 1 stop
Top airlines
Cheapest • from $347 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Louisville and Des Moines. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $196 (round-trip)
Shortest trip • 4h 24m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Louisville to Des Moines (SDF-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Louisville to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to Des Moines

Wed, May 20 - Sat, May 23
Multiple Airlines Logo
12:24 pm - 10:31 pm
SDF
-
DSM
35h 07m
2 stops
Multiple Airlines Logo
5:16 pm - 8:51 am
DSM
-
SDF
14h 35m
1 stop
$338Multiple Airlines
Fri, May 29 - Sun, Jun 7
American Airlines Logo
2:46 pm - 7:32 pm
SDF
-
DSM
5h 46m
1 stop
American Airlines Logo
5:00 am - 10:35 am
DSM
-
SDF
4h 35m
1 stop
$347American Airlines
Tue, Aug 18 - Wed, Aug 19
United Airlines Logo
9:00 am - 12:19 pm
SDF
-
DSM
4h 19m
1 stop
United Airlines Logo
1:40 pm - 10:51 pm
DSM
-
SDF
8h 11m
1 stop
$357United Airlines
Fri, May 29 - Sun, Jun 7
Delta Logo
8:10 am - 1:37 pm
SDF
-
DSM
6h 27m
1 stop
Delta Logo
5:35 am - 11:53 am
DSM
-
SDF
5h 18m
1 stop
$371Delta
Mon, May 18 - Tue, May 26
Delta Logo
5:47 pm - 10:32 pm
SDF
-
DSM
5h 45m
1 stop
Delta Logo
6:41 pm - 12:25 am
DSM
-
SDF
4h 44m
1 stop
$373Delta
Mon, May 18 - Mon, May 25
Delta Logo
5:47 pm - 10:32 pm
SDF
-
DSM
5h 45m
1 stop
Delta Logo
6:41 pm - 12:25 am
DSM
-
SDF
4h 44m
1 stop
$385Delta
Wed, May 20 - Sun, May 24
Delta Logo
6:00 am - 11:08 am
SDF
-
DSM
6h 08m
1 stop
Delta Logo
4:25 pm - 11:52 pm
DSM
-
SDF
6h 27m
1 stop
$403Delta
Tue, May 19 - Sun, May 24
American Airlines Logo
8:36 am - 11:30 am
SDF
-
DSM
3h 54m
1 stop
American Airlines Logo
5:00 am - 2:52 pm
DSM
-
SDF
8h 52m
2 stops
$408American Airlines
Fri, Jun 19 - Sun, Jun 21
Southwest Logo
8:05 pm - 11:30 pm
SDF
-
DSM
4h 25m
1 stop
Southwest Logo
5:10 am - 1:05 pm
DSM
-
SDF
6h 55m
2 stops
$412Southwest
Sun, May 17 - Sat, May 23
Allegiant Air Logo
9:14 pm - 5:43 pm
SDF
-
DSM
21h 29m
1 stop
Allegiant Air Logo
5:16 pm - 8:51 am
DSM
-
SDF
14h 35m
1 stop
$442Allegiant Air
Booking Insights

KAYAK's insights & trends for Louisville to Des Moines flights

Get data-powered insights and trends into flights from Louisville to Des Moines to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Louisville to Des Moines?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Louisville to Des Moines were found on American Airlines ($347) and United Airlines ($357).

Good to know

Cheapest flight$154
Flight from Louisville to Des Moines

When to book flights from Louisville to Des Moines

Are your dates flexible? Find out the best times to travel from Louisville to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Louisville to Des Moines

  • What is the cheapest flight from Louisville to Des Moines?

    In the last 3 days, the lowest price for a flight from Louisville to Des Moines was $154 for a one-way ticket and $338 for a round-trip.

  • Do I need a passport to fly between Louisville and Des Moines?

    No, a passport isn't needed to fly from Louisville to Des Moines. However, local authorities might ask for an official ID.

  • Which aircraft models fly most regularly from Louisville to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Louisville to Des Moines?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Louisville and Des Moines, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Louisville to Des Moines, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Louisville to Des Moines are Delta and United Airlines. With an average price for the route of $326 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $386 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Louisville to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Louisville to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Louisville to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Louisville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Louisville to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Louisville with another airline. Booking your flights between Louisville and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Louisville to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Louisville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Louisville to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Louisville to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Louisville to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8459 reviews
8.5Crew
8.1Boarding
7.8Entertainment
7.2Food
7.9Comfort
Airline reviews

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

8.0 ExcellentMatthew, May 2026
OKC - ATL
Read more Delta reviews

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

O’hsre taxi and deboarding took 40 minutes. Needed 20 minutes extra time between connecting flights to avoid running through terminal.

Overall a good experience, but no wifi available for free or for purchase and we got wet from condensation or other water source during descent.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

Standard flight with a drinks and a snack- overall very quick flight. The flight attendants were very strict, bordered on rude.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

Delayed - weather wasn't bad at either end. Also sat on tarmac in ORD.

They told us yesterday APR21st that they were cleaning the plane and we got delayed. After that they said they didn't had any crew for the flight so they cancelled the flight till next day.

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

Cancelled BOYH legs of our flight home 30 min before initial boarding

Cancelled the flight half hour before boarding. Then cancelled the connecting flight too.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

This was a hard flight. 3 delays out of OKC (1 on the Tarmac). Delay in Atlanta coming to Dallas. total travel time was the equivalent of driving from OKC to Atlanta.

Like: flights are on time, good boarding process Can improve: planes are old, improve entertainment and make space more comfortable

Everything you need to know for your flight from Louisville to Des Moines

Information on your arrival and departure airports