SDF - DSM

$124 Find Cheap Flights from Louisville to Des Moines - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$247
Typical prices: $294-$456
Delta
Mon 12/10Mon 12/17
SDF - DSM • 1 stop
Cheapest one-way
$124
Typical prices: $193-$291
Delta
Sun 11/25
SDF - DSM • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Louisville and Des Moines. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
September
Cheapest • 24% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Minneapolis St Paul (MSP)
Cheapest • Avg $276 (round-trip)
Chicago Midway (MDW)
Shortest trip • 3h 54m (one-way)
Insights
Insights
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Booking Insights
Flight Deals

Cheap Flights from Louisville to Des Moines (SDF-DSM)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to Des Moines

Thu, Dec 10 - Thu, Dec 17
Delta Logo
5:59 pm - 10:38 pmSDF  Louisville Intl-DSM Des Moines
5h 39m1 stop Atlanta Hartsfield-Jackson
Delta Logo
11:38 am - 7:13 pmDSM  Des Moines-SDF Louisville Intl
6h 35m1 stop Atlanta Hartsfield-Jackson
$247Delta
Thu, Dec 10 - Thu, Dec 17
Southwest Logo
12:55 pm - 10:05 pmSDF  Louisville Intl-DSM Des Moines
10h 10m2 stops Orlando Chicago Midway
Southwest Logo
5:25 am - 10:05 amDSM  Des Moines-SDF Louisville Intl
3h 40m1 stop Chicago Midway
$252Southwest
Tue, Nov 24 - Tue, Dec 1
Delta Logo
6:42 am - 10:19 amSDF  Louisville Intl-DSM Des Moines
4h 37m1 stop Minneapolis St Paul
Delta Logo
4:53 pm - 11:02 pmDSM  Des Moines-SDF Louisville Intl
5h 09m1 stop Minneapolis St Paul
$295Delta
Fri, Dec 11 - Sun, Dec 13
United Airlines Logo
5:40 pm - 9:25 pmSDF  Louisville Intl-DSM Des Moines
4h 45m1 stop Chicago O'Hare Intl
United Airlines Logo
1:15 pm - 9:00 pmDSM  Des Moines-SDF Louisville Intl
6h 45m1 stop Chicago O'Hare Intl
$311United Airlines
Fri, Dec 11 - Sun, Dec 13
Southwest Logo
5:35 pm - 11:05 pmSDF  Louisville Intl-DSM Des Moines
6h 30m2 stops Nashville Intl Chicago Midway
Southwest Logo
5:25 am - 10:05 amDSM  Des Moines-SDF Louisville Intl
3h 40m1 stop Chicago Midway
$316Southwest
Thu, Dec 10 - Thu, Dec 17
Southwest Logo
12:55 pm - 10:05 pmSDF  Louisville Intl-DSM Des Moines
10h 10m2 stops Orlando Chicago Midway
Southwest Logo
6:40 am - 3:05 pmDSM  Des Moines-SDF Louisville Intl
7h 25m2 stops Denver Intl Chicago Midway
$322Southwest
Fri, Dec 11 - Sun, Dec 13
Southwest Logo
5:35 pm - 11:05 pmSDF  Louisville Intl-DSM Des Moines
6h 30m2 stops Nashville Intl Chicago Midway
Southwest Logo
6:40 am - 9:05 pmDSM  Des Moines-SDF Louisville Intl
13h 25m2 stops Denver Intl Chicago Midway
$327Southwest
Thu, Dec 24 - Sat, Dec 26
United Airlines Logo
6:00 pm - 11:15 pmSDF  Louisville Intl-DSM Des Moines
6h 15m1 stop Chicago O'Hare Intl
United Airlines Logo
5:00 am - 1:18 pmDSM  Des Moines-SDF Louisville Intl
7h 18m1 stop Chicago O'Hare Intl
$336United Airlines
Tue, Nov 24 - Tue, Dec 1
Southwest Logo
8:35 pm - 11:35 pmSDF  Louisville Intl-DSM Des Moines
4h 00m1 stop Chicago Midway
Southwest Logo
7:00 am - 8:40 pmDSM  Des Moines-SDF Louisville Intl
12h 40m2 stops Denver Intl Nashville Intl
$367Southwest
Fri, Nov 27 - Mon, Nov 30
Delta Logo
6:42 am - 10:19 amSDF  Louisville Intl-DSM Des Moines
4h 37m1 stop Minneapolis St Paul
Delta Logo
2:59 pm - 10:53 pmDSM  Des Moines-SDF Louisville Intl
6h 54m1 stop Atlanta Hartsfield-Jackson
$372Delta
Booking Insights

Price, demand and travel trends for Louisville to Des Moines flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Louisville to Des Moines?

Round-trip flights from Louisville to Des Moines typically range from $294 to $456. The lowest price found in the past 5 days was $247, on Delta.

What's the cheapest day of the week to fly from Louisville to Des Moines?

Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from Louisville to Des Moines. It’s 12% cheaper than the average day, while Monday is the most expensive, with prices 55% higher.

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Key details for Louisville to Des Moines flights

Low season

March

Cheapest flight

$124
Beat the crowds with an average 91% drop in travelers.
The most popular month to fly with an average 54% increase in travelers.
One-way flight from Louisville to Des Moines

When to book flights from Louisville to Des Moines

Are your dates flexible? Find out the best times to travel from Louisville to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Louisville to Des Moines flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Louisville to Des Moines?

    Only Economy Class is available on flights from Louisville to Des Moines.

  • How long is a flight from Louisville to Des Moines?

    A nonstop flight from Louisville to Des Moines takes 00m, covering 480 miles.

  • Do I need a passport to fly from Louisville to Des Moines?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Louisville to Des Moines flight?

    Round-trip flights from Louisville to Des Moines range from $294 to $456, with an average of $346 over the past 12 months. Anything below $294 counts as a good deal.

  • Have flight prices from Louisville to Des Moines changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $247 to $925. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Louisville to Des Moines looking right now?

    One-way fares from Louisville to Des Moines are currently in line with typical prices for this route. Average one-way fares are about $270.

  • What car rental options are available at Des Moines Airport (DSM)?

    Des Moines Airport (DSM) hosts 5 major car rental companies, with daily rates averaging $81 for economy cars. Top options include:

    • Hertz
    • Payless
    • Budget
    • Alamo
    • Avis

  • Which airports can I use when flying from Louisville to Des Moines?

    Flights from Louisville to Des Moines usually depart from Louisville Intl (SDF) and arrive at Des Moines (DSM).

  • Which airports do connecting flights from Louisville to Des Moines pass through?

    One-stop flights from Louisville to Des Moines most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 71% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 9% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 9% of one-stop connections
    • Chicago Midway (MDW) - 9% of one-stop connections

  • Can I save money by using flexible dates for flights from Louisville to Des Moines?

    Yes. Flexible dates can save you up to 44% on flights from Louisville to Des Moines. Thursday is the cheapest departure day at $305 round-trip on average, while Monday is the most expensive at $537, a difference of $232.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Louisville to Des Moines?

    Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 3h 54m, compared with 4h 30m via Detroit Metropolitan Wayne County (DTW) and 4h 40m via Atlanta Hartsfield-Jackson (ATL).

  • What is the time difference between Louisville and Des Moines?

    Des Moines is 1 hour behind Louisville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Des Moines?

    Some of the most popular sights in Des Moines are UnityPoint Health - Des Moines, Science Center of Iowa and Hy Vee Hall. These are among the most viewed places in Des Moines on KAYAK.

Your guide to booking Louisville to Des Moines flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure and avoid flying on Monday. On this route, Thursday flights average $305, about $232 less than Monday fares (43% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Louisville to Des Moines trip for September. Fares historically average $263 round-trip in that month - typically $195 less than the most expensive month, which is May (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Des Moines Airport.

    • Days Inn & Suites by Wyndham Des Moines Airport
    • Quality Inn & Suites Des Moines Airport
    • Homewood Suites by Hilton - Des Moines Airport

More options for your flight from Louisville to Des Moines

Complete your trip to Des Moines with a hotel stay or car rental

Car rentals in Des Moines
Hotels in Des Moines
Vacations in Des Moines