SDF - DSM

$133 Find Cheap Flights from Louisville to Des Moines - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$249
Typical prices: $294-$458
Delta
Fri 10/5Sun 10/7
SDF - DSM • 1 stop
Cheapest one-way
$133
Typical prices: $185-$276
Delta
Fri 10/5
SDF - DSM • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Louisville and Des Moines. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
March
Cheapest • 20% price drop
August
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Atlanta Hartsfield-Jackson (ATL)
Cheapest • Avg $246 (round-trip)
Chicago Midway (MDW)
Shortest trip • 3h 47m (one-way)
Insights
Insights
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Booking Insights
Flight Deals

Cheap Flights from Louisville to Des Moines (SDF-DSM)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Louisville to Des Moines

Mon, Oct 5 - Wed, Oct 7
Delta Logo
7:05 am - 10:46 amSDF  Louisville Intl-DSM Des Moines
4h 41m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:54 pm - 11:59 pmDSM  Des Moines-SDF Louisville Intl
4h 05m1 stop Atlanta Hartsfield-Jackson
$249Delta
Mon, Oct 5 - Wed, Oct 7
United Airlines Logo
9:04 am - 2:15 pmSDF  Louisville Intl-DSM Des Moines
6h 11m1 stop Chicago O'Hare Intl
United Airlines Logo
11:27 am - 7:11 pmDSM  Des Moines-SDF Louisville Intl
6h 44m1 stop Chicago O'Hare Intl
$249United Airlines
Wed, Oct 21 - Fri, Oct 23
Southwest Logo
7:10 pm - 10:00 pmSDF  Louisville Intl-DSM Des Moines
3h 50m1 stop Chicago Midway
Southwest Logo
7:10 pm - 10:20 amDSM  Des Moines-SDF Louisville Intl
14h 10m2 stops Denver Intl Chicago Midway
$275Southwest
Wed, Oct 21 - Fri, Oct 23
Southwest Logo
10:40 am - 10:00 pmSDF  Louisville Intl-DSM Des Moines
12h 20m2 stops Baltimore/Washington Chicago Midway
Southwest Logo
7:10 pm - 10:20 amDSM  Des Moines-SDF Louisville Intl
14h 10m2 stops Denver Intl Chicago Midway
$286Southwest
Wed, Oct 21 - Fri, Oct 23
United Airlines Logo
5:15 am - 10:31 amSDF  Louisville Intl-DSM Des Moines
6h 16m1 stop Chicago O'Hare Intl
United Airlines Logo
6:55 pm - 11:59 pmDSM  Des Moines-SDF Louisville Intl
4h 04m1 stop Chicago O'Hare Intl
$298United Airlines
Tue, Nov 10 - Wed, Nov 11
United Airlines Logo
8:00 am - 12:31 pmSDF  Louisville Intl-DSM Des Moines
5h 31m1 stop Denver Intl
United Airlines Logo
1:27 pm - 10:24 pmDSM  Des Moines-SDF Louisville Intl
7h 57m1 stop Denver Intl
$303United Airlines
Mon, Nov 2 - Thu, Nov 5
Southwest Logo
8:45 am - 11:30 amSDF  Louisville Intl-DSM Des Moines
3h 45m1 stop Chicago Midway
Southwest Logo
5:25 am - 10:05 amDSM  Des Moines-SDF Louisville Intl
3h 40m1 stop Chicago Midway
$340Southwest
Mon, Oct 5 - Wed, Oct 7
United Airlines Logo
9:04 am - 12:34 pmSDF  Louisville Intl-DSM Des Moines
4h 30m1 stop Chicago O'Hare Intl
United Airlines Logo
8:00 am - 7:24 pmDSM  Des Moines-SDF Louisville Intl
10h 24m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National
$356United Airlines
Mon, Oct 5 - Wed, Oct 7
Southwest Logo
5:35 am - 11:10 amSDF  Louisville Intl-DSM Des Moines
6h 35m2 stops Baltimore/Washington Chicago Midway
Southwest Logo
5:35 am - 10:05 amDSM  Des Moines-SDF Louisville Intl
3h 30m1 stop Chicago Midway
$366Southwest
Fri, Oct 2 - Mon, Oct 5
Delta Logo
5:50 pm - 8:46 pmSDF  Louisville Intl-DSM Des Moines
3h 56m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:54 pm - 11:59 pmDSM  Des Moines-SDF Louisville Intl
4h 05m1 stop Atlanta Hartsfield-Jackson
$443Delta
Booking Insights

Price, demand and travel trends for Louisville to Des Moines flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Louisville to Des Moines with more confidence.

How much is a round-trip flight from Louisville to Des Moines?

Round-trip flights from Louisville to Des Moines start at $249. Prices are below average for this route right now, with typical round-trip fares ranging from $294 to $458. The lowest price found in the past 5 days was $249 on Delta.

What's the cheapest day of the week to fly from Louisville to Des Moines?

Thursday is the cheapest day of the week to fly from Louisville to Des Moines, it is 12% cheaper than the average day. Wednesday is the most expensive day with flight prices 83% higher than average. Based on deals found by KAYAK users in the last 12 months.

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Key details for Louisville to Des Moines flights

Low season

March

Cheapest flight

$133
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly with an average 20% increase in price.
Flight from Louisville to Des Moines

When to book flights from Louisville to Des Moines

Are your dates flexible? Find out the best times to travel from Louisville to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Louisville to Des Moines flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Louisville to Des Moines?

    Flights from Louisville to Des Moines usually depart from Louisville Intl (SDF) and arrive at Des Moines (DSM).

  • What cabin classes can I book on flights from Louisville to Des Moines?

    Two cabin classes are available on flights from Louisville to Des Moines:

    • Economy Class
    • First Class

  • Which airports do connecting flights from Louisville to Des Moines pass through?

    One-stop flights from Louisville to Des Moines most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 78% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 8% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 8% of one-stop connections
    • Chicago Midway (MDW) - 3% of one-stop connections

    Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Louisville to Des Moines?

    Yes. Being flexible with your travel dates can save you up to 52% on the Louisville to Des Moines route. Thursday is the cheapest departure day at $305 round-trip on average, while Wednesday is the most expensive at $634, a difference of $329. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Des Moines?

    Some of the most popular sights in Des Moines are UnityPoint Health - Des Moines, Science Center of Iowa and Hy Vee Hall. These are among the most viewed places in Des Moines on KAYAK.

  • How long is a flight from Louisville to Des Moines?

    A nonstop flight from Louisville to Des Moines takes 0h 00m, covering 480 miles.

  • Do I need a passport to fly from Louisville to Des Moines?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Louisville to Des Moines changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $249 to $925. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Louisville to Des Moines looking right now?

    One-way fares from Louisville to Des Moines are currently lower than usual. Average one-way flight prices are about $205, which is 19% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Louisville to Des Moines?

    Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 3h 47m, compared with 4h 30m via Detroit Metropolitan Wayne County (DTW) and 4h 50m via Minneapolis St Paul (MSP).

  • What is the time difference between Louisville and Des Moines?

    Des Moines is 1 hour behind Louisville (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Des Moines Airport (DSM)?

    Des Moines Airport (DSM) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    • Hertz
    • Payless
    • Budget
    • Alamo
    • Avis

  • How much should I expect to pay for a Louisville to Des Moines flight?

    Round-trip flights from Louisville to Des Moines range from $294 to $458, with an average of $346 over the past 12 months. Anything below $294 counts as a good deal.

Your guide to booking Louisville to Des Moines flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Thursday departure instead of Wednesday. On this route, Thursday flights average $305 - about $329 less than Wednesday (52% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Louisville to Des Moines trip for March. Fares historically average $276 round-trip in that month - typically $182 less than the most expensive month, which is May (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Des Moines Airport.
    - Days Inn & Suites by Wyndham Des Moines Airport
    - Quality Inn & Suites Des Moines Airport
    - Holiday Inn Des Moines-Airport/Conf Center By IHG

More options for your flight from Louisville to Des Moines

Complete your trip to Des Moines with a hotel stay or car rental

Car rentals in Des Moines
Hotels in Des Moines
Vacations in Des Moines