DSM - SDF

$140 Find Cheap Flights from Des Moines to Louisville - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Louisville departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$279
Typical prices: $353-$376
Delta
Tue 10/27Sat 10/31
DSM - SDF • 1 stop
Cheapest one-way
$140
Typical prices: $178-$243
Delta
Thu 8/27
DSM - SDF • 1 stop
Top airlines
Cheapest • from $279 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Louisville. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $350 (round-trip)
Shortest trip • 3h 52m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 40% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Louisville (DSM-SDF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Louisville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Louisville

Tue, Oct 27 - Sat, Oct 31
Delta Logo
6:54 pm - 11:59 pm
DSM
-
SDF
4h 05m
1 stop
Delta Logo
7:00 am - 10:11 am
SDF
-
DSM
4h 11m
1 stop
$279Delta
Tue, Oct 27 - Sat, Oct 31
American Airlines Logo
2:01 pm - 9:35 pm
DSM
-
SDF
6h 34m
1 stop
American Airlines Logo
6:14 pm - 12:04 am
SDF
-
DSM
6h 50m
1 stop
$279American Airlines
Tue, Oct 27 - Sat, Oct 31
Southwest Logo
5:35 am - 10:05 am
DSM
-
SDF
3h 30m
1 stop
Southwest Logo
12:35 pm - 5:45 pm
SDF
-
DSM
6h 10m
1 stop
$279Southwest
Tue, Oct 27 - Sat, Oct 31
Southwest Logo
5:35 am - 4:30 pm
DSM
-
SDF
9h 55m
2 stops
Southwest Logo
9:15 am - 11:50 am
SDF
-
DSM
3h 35m
1 stop
$284Southwest
Tue, Oct 27 - Sat, Oct 31
American Airlines Logo
2:01 pm - 9:35 pm
DSM
-
SDF
6h 34m
1 stop
American Airlines Logo
6:14 pm - 12:04 am
SDF
-
DSM
6h 50m
1 stop
$299American Airlines
Fri, Oct 23 - Mon, Oct 26
United Airlines Logo
1:24 pm - 8:31 pm
DSM
-
SDF
6h 07m
1 stop
United Airlines Logo
7:00 am - 10:26 am
SDF
-
DSM
4h 26m
1 stop
$304United Airlines
Thu, Aug 27 - Sun, Aug 30
Delta Logo
5:40 am - 12:21 pm
DSM
-
SDF
5h 41m
1 stop
Delta Logo
6:50 am - 10:18 am
SDF
-
DSM
4h 28m
1 stop
$318Delta
Mon, Oct 26 - Sun, Nov 1
Delta Logo
3:46 pm - 10:51 pm
DSM
-
SDF
6h 05m
1 stop
Delta Logo
7:05 am - 10:42 am
SDF
-
DSM
4h 37m
1 stop
$318Delta
Fri, Aug 28 - Fri, Sep 4
United Airlines Logo
11:32 am - 7:07 pm
DSM
-
SDF
6h 35m
1 stop
United Airlines Logo
9:00 am - 2:16 pm
SDF
-
DSM
6h 16m
1 stop
$329United Airlines
Fri, Aug 28 - Fri, Sep 4
American Airlines Logo
1:55 pm - 9:25 pm
DSM
-
SDF
6h 30m
1 stop
American Airlines Logo
6:28 am - 10:00 am
SDF
-
DSM
4h 32m
1 stop
$343American Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Louisville flights

Get data-powered insights and trends into flights from Des Moines to Louisville to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to Louisville?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Louisville departing in October.

Flight prices are below average for this route right now.

Flights to Louisville from Des Moines usually cost between $335 and $466 in October.
The lowest price found in the past 5 days was $279 on Southwest (Oct 27-Oct 31).

What is the cheapest month to fly from Des Moines to Louisville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Louisville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Louisville is January, where tickets cost $260 (return) on average. On the other hand, the most expensive months are December and February, where the average cost of round-trip tickets is $626 and $536 respectively.

Good to know

Low season

November

Cheapest flight

$140
Best time to beat the crowds but there is an average 24% increase in price.
Most popular time to fly and prices are also 15% lower on average.
Flight from Des Moines to Louisville

When to book flights from Des Moines to Louisville

Are your dates flexible? Find out the best times to travel from Des Moines to Louisville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Louisville

  • What is the cheapest flight from Des Moines to Louisville?

    In the last 5 days, the lowest price for a flight from Des Moines to Louisville was $140 for a one-way ticket and $279 for a round-trip.

  • Do I need a passport to fly between Des Moines and Louisville?

    A passport is not required to fly from Des Moines to Louisville.

  • Which airports will I be using when flying from Des Moines to Louisville?

    When flying out of Des Moines you will be using Des Moines. You will be landing at Louisville, also known as Louisville Intl.

  • Which aircraft models fly most regularly from Des Moines to Louisville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Louisville?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Des Moines and Louisville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Louisville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Louisville are Delta and United Airlines. With an average price for the route of $446 and an overall rating of 7.8, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $409 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to Louisville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Louisville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Louisville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Louisville from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Louisville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Louisville with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SDF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Louisville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Louisville from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Des Moines to Louisville

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Louisville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Louisville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8497 reviews
8.1Boarding
7.8Entertainment
8.5Crew
7.8Comfort
7.2Food
Airline reviews

Comfortable seats. Nice service online. Short flight, so not a lot of time to enjoy.

8.0 ExcellentMichael, Jul 2026
SEA - SMF
Read more Delta reviews

Comfortable seats. Nice service online. Short flight, so not a lot of time to enjoy.

Awful. There was an unexpected delay of nearly three hours because there were not enough flight attendants. I understand this is likely due to FAA regulations; but in that case, Delta should coordinate with smaller airports such as RDU to have extra flight attendants on the ground and "on call". In addition, this was the second 2-hour+ delay to Boston on this route in one week.

It was strange that the flight attendant was so adamant about having phones turned to airplane mode that he was calling out names from networks shown and waiting until they were all gone. I've never experienced that before, and after already working through an hour+ delay, it felt tone deaf. I take dozens of flights per year and have never experienced anything similar.

The flight was done by SkyWest only WIFI no entertainment center are available on the CRJ

Your survey needs a N/A option. I didn’t use the entertainment or eat food.

The flight was over 2 hours late.. once we finally got boarded things were fine

Poor communication, we sat on the plane for an hour before pushing back. They were oversold and with a full plane kept looking for someone to step off for someone else to board. So after an hour wait at the gate we missed our departure window and proceeded to spend an additional hour on the tarmac waiting for a refiled flight plan according to the pilots. Occasional updates, somewhat insensitive crew to passengers needing to use the lavatory (it was 2 hrs beyond what anyone expected). Overall just poor execution...especially when the flight was listed as "arriving early" up until about 30 minutes past our departure time.

No tv. No free wifi. They need to ipgrade these planes - especially on a 2 hour flight.

I am writing to express my dissatisfaction with the poor service and unprofessional staff we encountered when traveling with an infant. Our flight was delayed, and the gate staff failed to manage the boarding process appropriately. Due to incorrect, unavailable, or missing 'pink tag' stroller and car seat check-in procedures at the gate, we were forced to board last. Furthermore, the gate staff was rude and dismissive, causing significant distress to our infant. To make matters worse, one of our checked items—an infant sleeper/lounger—was returned to us broken. Given the unsafe handling of essential equipment and unprofessional treatment, I expect a prompt resolution regarding compensation for the damaged items.

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The flight crew were very helpful. The seats were very close together. There was barely room to sit without touching the person next to you.

I’m an EP on AA every year for more than a decade but this was a very pleasant and surprising experience. Clean and sizable plane for HOU to CHI. 5 row first class. And excellent food in first class the steak option was really good. Your flight attendants even better. Seat 5A

It was hot and not as comfortable as the flight to Chicago. Must have been a different plane that needs to be worked on or replaced.

My flight was delayed so bad i missed u it so i just said never mind

1 flight cancelled Had to fly out of different city Flight at new departure city was delayed 3 hours causing us to miss connecting flights. By the time we did make it to Prague our luggage did not. Had to wait day and a half for luggage to be delivered. Customer service was not good. Agents did not arrive at gate until 5-10 minutes before boarding

It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Very rough getting into denver. my kid threw up it was so rough.

Liked that we left on time for each flight. Snacks not the best, but we're okay.

I had requested wheelchair assistance prior to flight. The airport staff had no record of it. It was not provided at Cedar Rapids which was a small airport, so I managed on my own. At O'Hare airport the same thing happened. The staff told me they had no record of my request for a wheel chair. But they finally provided it after a delay when I insisted that I needed it.

The gate got changed several times and the flight was delayed over an hour. Awful experience

It was an older plane. First Class was not especially roomy or comfortable. It was a short flight so there were no meal but they did offer mixed nuts which used to be normal but now is rare. Crew member was very polite and professional.

No Snacks or Entertainment. The flight was short, snacks should still be given.

In flight connectivity (via T-Mobile) was often not working.

Everything was fine. Flight boarded and departed on time. Seating was spacious enough for my carryon to fit under the seat in front of me. No complaints at all. Flight even arrived early.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

Boston ticket agent Cheryl Porter is WONDERFUL. Our Iberia flight to Barcelona was cancelled the morning we were scheduled to leave and Cheryl was our super hero - she found us seats on a flight to London and on to Barcelona. Truly a “can-do” attitude which we appreciated so much after the Iberia ticket agents told us there was “absolutely nothing they could do”. (As did the customer service agents at Iberia’s call center) Ms Porter is truly a wonderful person who genuinely cares about travelers!

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Nothing wrong on this flight but nothing special. It was oversold and they had to bump people which is always bad.

Everything you need to know for your flight from Des Moines to Louisville

Information on your arrival and departure airports