DSM - SDF

$144 Find Cheap Flights from Des Moines to Louisville - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$247
Typical prices: $311-$452
Delta
Fri 12/7Sat 12/8
DSM - SDF • 1 stop
Cheapest one-way
$144
Typical prices: $257-$294
Delta
Tue 12/4
DSM - SDF • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Louisville. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
January
Cheapest • 33% price drop
September
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Chicago Midway (MDW)
Cheapest • Avg $339 (round-trip)
Chicago O'Hare Intl (ORD)
Shortest trip • 4h 36m (one-way)
Insights
Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Louisville (DSM-SDF)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Louisville

Mon, Dec 7 - Tue, Dec 8
Delta Logo
6:53 pm - 12:09 amDSM  Des Moines-SDF Louisville Intl
4h 16m1 stop Atlanta Hartsfield-Jackson
Delta Logo
8:05 am - 2:13 pmSDF  Louisville Intl-DSM Des Moines
7h 08m1 stop Atlanta Hartsfield-Jackson
$247Delta
Mon, Dec 7 - Tue, Dec 8
Southwest Logo
3:25 pm - 8:35 pmDSM  Des Moines-SDF Louisville Intl
4h 10m1 stop Chicago Midway
Southwest Logo
5:40 am - 11:25 amSDF  Louisville Intl-DSM Des Moines
6h 45m2 stops Baltimore/Washington Chicago Midway
$252Southwest
Fri, Nov 27 - Thu, Dec 3
Southwest Logo
5:25 am - 10:05 amDSM  Des Moines-SDF Louisville Intl
3h 40m1 stop Chicago Midway
Southwest Logo
6:50 am - 2:15 pmSDF  Louisville Intl-DSM Des Moines
8h 25m1 stop Denver Intl
$267Southwest
Wed, Dec 9 - Tue, Jan 19
United Airlines Logo
3:20 pm - 9:00 pmDSM  Des Moines-SDF Louisville Intl
4h 40m1 stop Chicago O'Hare Intl
United Airlines Logo
7:00 am - 12:17 pmSDF  Louisville Intl-DSM Des Moines
6h 17m1 stop Chicago O'Hare Intl
$271United Airlines
Wed, Nov 18 - Sun, Nov 22
Delta Logo
11:36 am - 7:14 pmDSM  Des Moines-SDF Louisville Intl
6h 38m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:42 am - 10:19 amSDF  Louisville Intl-DSM Des Moines
4h 37m1 stop Minneapolis St Paul
$291Delta
Fri, Nov 27 - Sat, Nov 28
United Airlines Logo
8:00 am - 1:35 pmDSM  Des Moines-SDF Louisville Intl
4h 35m1 stop Chicago O'Hare Intl
United Airlines Logo
5:10 am - 10:30 amSDF  Louisville Intl-DSM Des Moines
6h 20m1 stop Chicago O'Hare Intl
$332United Airlines
Wed, Mar 3 - Tue, Mar 9
American Airlines Logo
2:02 pm - 9:31 pmDSM  Des Moines-SDF Louisville Intl
6h 29m1 stop Chicago O'Hare Intl
American Airlines Logo
6:00 am - 1:32 pmSDF  Louisville Intl-DSM Des Moines
8h 32m2 stops Charlotte Douglas Chicago O'Hare Intl
$437American Airlines
Mon, Nov 9 - Thu, Nov 12
Multiple Airlines Logo
10:24 am - 5:33 pmDSM  Des Moines-SDF Louisville Intl
6h 09m1 stop Tampa St. Petersburg
Multiple Airlines Logo
9:09 pm - 7:54 amSDF  Louisville Intl-DSM Des Moines
11h 45m1 stop Tampa
$495Multiple Airlines
Mon, Nov 9 - Thu, Nov 12
Multiple Airlines Logo
10:24 am - 5:33 pmDSM  Des Moines-SDF Louisville Intl
6h 09m1 stop Tampa St. Petersburg
Multiple Airlines Logo
9:09 pm - 7:54 amSDF  Louisville Intl-DSM Des Moines
11h 45m1 stop Tampa
$497Multiple Airlines
Wed, Mar 31 - Fri, Apr 2
American Airlines Logo
7:18 am - 6:21 pmDSM  Des Moines-SDF Louisville Intl
10h 03m2 stops Chicago O'Hare Intl Charlotte Douglas
American Airlines Logo
6:14 pm - 12:43 amSDF  Louisville Intl-DSM Des Moines
7h 29m1 stop Chicago O'Hare Intl
$550American Airlines
Booking Insights

Price, demand and travel trends for Des Moines to Louisville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Des Moines to Louisville?

Round-trip flights from Des Moines to Louisville typically range from $311 to $452. The lowest price found in the past 5 days was $247, on Delta.

What's the cheapest day of the week to fly from Des Moines to Louisville?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Des Moines to Louisville. It’s 33% cheaper than the average day, while Sunday is the most expensive, with prices 84% higher.

What’s the cheapest month to fly from Des Moines to Louisville?

•January is the cheapest month to fly from Des Moines to Louisville at $260 round-trip.
•November ($715) and December ($626) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 175% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Des Moines to Louisville flights

Low season

January

Cheapest flight

$144
Beat the crowds with an average 45% drop in travelers.
The most popular month to fly with an average 45% increase in travelers.
One-way flight from Des Moines to Louisville

When to book flights from Des Moines to Louisville

Are your dates flexible? Find out the best times to travel from Des Moines to Louisville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Louisville flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to Louisville?

    Only Economy Class is available on flights from Des Moines to Louisville.

  • How long is a flight from Des Moines to Louisville?

    A nonstop flight from Des Moines to Louisville takes 00m, covering 480 miles.

  • Do I need a passport to fly from Des Moines to Louisville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Des Moines to Louisville flight?

    Round-trip flights from Des Moines to Louisville range from $311 to $452, with an average of $387 over the past 12 months. Anything below $311 counts as a good deal.

  • Have flight prices from Des Moines to Louisville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $247 to $1,273. That means the highest observed fare was about 5x higher than the lowest one.

  • How are flight prices from Des Moines to Louisville looking right now?

    One-way fares from Des Moines to Louisville are currently lower than usual. Average one-way flight prices are about $196, which is 31% below the typical average for this route.

  • What car rental options are available at Louisville Intl Airport (SDF)?

    Louisville Intl Airport (SDF) hosts 5 major car rental companies, with daily rates averaging $75 for economy cars. Top options include:

    • Hertz
    • Dollar
    • Alamo
    • Thrifty
    • Budget

  • Which airports can I use when flying from Des Moines to Louisville?

    Flights from Des Moines to Louisville usually depart from Des Moines (DSM) and arrive at Louisville Intl (SDF).

  • Which airports do connecting flights from Des Moines to Louisville pass through?

    One-stop flights from Des Moines to Louisville most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 54% of one-stop connections
    • Chicago Midway (MDW) - 29% of one-stop connections
    • Minneapolis St Paul (MSP) - 12% of one-stop connections
    • Dallas/Fort Worth (DFW) - 2% of one-stop connections

  • Can I save money by using flexible dates for flights from Des Moines to Louisville?

    Yes. Flexible dates can save you up to 64% on flights from Des Moines to Louisville. Tuesday is the cheapest departure day at $260 round-trip on average, while Sunday is the most expensive at $715, a difference of $455.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Des Moines to Louisville?

    Flying via Chicago Midway (MDW) gives the shortest average 1-stop total travel time at 3h 46m, compared with 4h 36m via Chicago O'Hare Intl (ORD) and 4h 38m via Minneapolis St Paul (MSP).

  • What is the time difference between Des Moines and Louisville?

    Louisville is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Louisville?

    Some of the most popular sights in Louisville are Louisville Waterfront Park and Masonic Widows and Orphans Home. These are among the most viewed places in Louisville on KAYAK.

Your guide to booking Des Moines to Louisville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Sunday. On this route, Tuesday flights average $260, about $455 less than Sunday fares (64% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Louisville trip for January. Fares historically average $260 round-trip in that month - typically $455 less than the most expensive month, which is November (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Louisville Intl Airport.

    • Crowne Plaza Louisville Airport Expo Ctr By IHG
    • SpringHill Suites by Marriott Louisville Airport
    • Staybridge Suites Louisville - Expo Center By IHG

More options for your flight from Des Moines to Louisville

Complete your trip to Louisville with a hotel stay or car rental

Car rentals in Louisville
Hotels in Louisville
Vacations in Louisville