MDE - PTY

$156 Find Cheap Flights from Medellín to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to Panama City departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Panama City, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Medellín to Panama City (MDE-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to Panama City

Fri, Oct 17 - Tue, Oct 21
Copa Airlines Logo
3:29 pm - 4:57 pmMDE-PTY
1h 28mnonstop
Copa Airlines Logo
12:00 pm - 1:25 pmPTY-MDE
1h 25mnonstop
$264Copa Airlines
Find Deal
Wed, Nov 5 - Wed, Nov 12
Copa Airlines Logo
9:17 am - 10:45 amMDE-PTY
1h 28mnonstop
Copa Airlines Logo
7:25 am - 8:49 amPTY-MDE
1h 24mnonstop
$265Copa Airlines
Find Deal
Thu, Nov 6 - Thu, Nov 13
Avianca Logo
12:40 pm - 4:55 pmMDE-PTY
4h 15m1 stop
Avianca Logo
2:55 pm - 7:10 pmPTY-MDE
4h 15m1 stop
$269Avianca
Find Deal
Mon, Dec 8 - Sun, Dec 14
Copa Airlines Logo
9:17 am - 10:45 amMDE-PTY
1h 28mnonstop
Copa Airlines Logo
8:28 am - 9:51 amPTY-MDE
1h 23mnonstop
$275Copa Airlines
Find Deal
Fri, Dec 5 - Mon, Dec 8
Copa Airlines Logo
3:15 pm - 4:44 pmMDE-PTY
1h 29mnonstop
Copa Airlines Logo
6:54 am - 8:18 amPTY-MDE
1h 24mnonstop
$276Copa Airlines
Find Deal
Wed, Nov 5 - Sun, Nov 9
Avianca Logo
4:20 am - 8:50 amMDE-PTY
4h 30m1 stop
Avianca Logo
2:55 am - 7:05 amPTY-MDE
4h 10m1 stop
$277Avianca
Find Deal
Tue, Mar 17 - Mon, Mar 23
Avianca Logo
9:50 am - 2:00 pmMDE-PTY
4h 10m1 stop
Avianca Logo
2:55 am - 7:05 amPTY-MDE
4h 10m1 stop
$278Avianca
Find Deal
Mon, Oct 27 - Fri, Oct 31
Copa Airlines Logo
10:46 am - 12:15 pmMDE-PTY
1h 29mnonstop
Copa Airlines Logo
12:51 pm - 2:15 pmPTY-MDE
1h 24mnonstop
$283Copa Airlines
Find Deal
Wed, Nov 19 - Wed, Nov 26
Avianca Logo
4:20 am - 8:50 amMDE-PTY
4h 30m1 stop
Avianca Logo
2:55 am - 7:05 amPTY-MDE
4h 10m1 stop
$284Avianca
Find Deal
Fri, Oct 17 - Tue, Oct 21
Multiple Airlines Logo
6:37 am - 8:02 amMDE-PTY
1h 25mnonstop
Multiple Airlines Logo
5:25 pm - 9:32 pmPTY-MDE
4h 07m1 stop
$325Multiple Airlines
Find Deal

Everything you should know

Our travelers' advice
AI-generated summary based on content written by travel experts
Avianca's Classic fare includes a free checked bag.
Copa's Showpass system works on personal devices.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Copa Airlines
Cheapest • from $264 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
5 weeks
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 8% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 11% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$264
Typical prices: $167-263
Copa Airlines
Fri 10/17Tue 10/21
MDE - PTY • Non-stop
Cheapest non-stop
$264
Typical prices: $159-236
Copa Airlines
Sat 11/1Sun 11/2
MDE - PTY • Non-stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Booking Insights

KAYAK's insights & trends for Medellín to Panama City flights

Get data-powered insights and trends into flights from Medellín to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Medellín Jose Maria Cordova Intl Airport to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Medellín Jose Maria Cordova Intl Airport to Panama City departing in October.

What’s the cheapest day of the week to fly from Medellín to Panama City?

The average price of all round-trip flights from Medellín Jose Maria Cordova Intl Airport to Panama City clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Panama City on a Friday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from Medellín to Panama City. For your return ticket, we recommend flying on a Wednesday and avoiding Sundays for the best deals.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to Panama City is May, where tickets cost $164 (return) on average. On the other hand, the most expensive months are December and January, where the average cost of round-trip tickets is $211 and $205 respectively.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to Panama City, you should book around 5 weeks before departure, which saves you about 8% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Expert advice

Expert advice for your flight from Medellín to Panama City

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Copa Airlines

Copa's Economy Extra seats offer more space, recommended for comfort on longer flights.


Copa's Showpass entertainment system is accessible via personal devices on newer aircraft.

Avianca

Avianca's Classic fare includes a free checked bag and seat selection, ideal for budget-conscious travelers.


Avianca's LifeMiles program offers flexible point transfers from major credit cards for reward travel.

Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on Copa Airlines

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Mark Chesnut

Mark Chesnut

Expert on Avianca

Mark Chesnut

Mark Chesnut

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more

Good to know

Low seasonMay
Cheapest flight$155
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 9% increase in price.
Flight from Medellín to Panama City

When to book flights from Medellín to Panama City

Are your dates flexible? Find out the best times to travel from Medellín to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to Panama City flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to Panama City?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to Panama City was $155 for a one-way ticket and $264 for a round-trip.

  • Do I need a passport to fly between Medellín and Panama City?

    Yes

  • Which airports will I be using when flying from Medellín to Panama City?

    Medellín airport is called Medellín Jose Maria Cordova Intl and the only airport in Panama City is Panama City Tocumen Intl.

  • Which airlines offer Wi-Fi service onboard planes from Medellín to Panama City?

    American Airlines, JetBlue, LATAM Airlines, and Delta offer inflight Wi-Fi service on the Medellín to Panama City flight route.

  • Which aircraft models fly most regularly from Medellín to Panama City?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Medellín to Panama City flight route.

  • Which airline alliances offer flights from Medellín to Panama City?

    Star Alliance is the only airline alliance operating flights between Medellín and Panama City.

  • On which days can I fly direct from Medellín to Panama City?

    There are nonstop flights from Medellín to Panama City on a daily basis.

  • Which is the best airline for flights from Medellín to Panama City, Copa Airlines or Wingo?

    The two airlines most popular with KAYAK users for flights from Medellín to Panama City are Copa Airlines and Wingo. With an average price for the route of $284 and an overall rating of 7.6, Copa Airlines is the most popular choice. Wingo is also a great choice for the route, with an average price of $178 and an overall rating of 7.3.

  • How does KAYAK find such low prices on flights from Medellín to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Medellín with another airline. Booking your flights between Medellín and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Medellín Jose Maria Cordova Intl Airport to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $225 or less one-way and $282 or less round-trip.

Prefer to fly direct from Medellín to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl.
Find which airlines fly direct from Medellín Jose Maria Cordova Intl Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top 3 airlines serving from Medellín to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Medellín to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1542 reviews
8.1Crew
7.4Comfort
6.8Food
7.8Boarding
6.8Entertainment
Airline reviews

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

10.0 ExcellentMichael, Sep 2025PBM - PTY
Read more Copa Airlines reviews

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Seats not reclining, no vegetarian food option, no snacks. 7.5 hr flight should have been more comfortable. Luggage limits are unusually small. Will never fly Copa again and will tell friends and family to avoid this airline.

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

Delay at the airport was not clearly communicated. No announcements were made and since we are foreigners it was very hard to know what was happening at the Wingo gate.

That they were on tike but, They charge again for baggage while we already paid when we buy our tickets

Perfect for a very low cost flight. In time, safety perfect, and of course no service, just what you effectivement !

Delayed three hours and they knew it but didn’t say anything upon checking in

Cumple con su función, transportar, no incluye comida a menos que se pague un valor adicional y así mismo con los asientos y demás, brindan precios económicos pero tratan de compensarlo cobrando por todo lo demás, si desean un viaje económico y que no dure más de 3 horas el vuelo, recomendando

i was seated apart from my girlfriend even though I bought the tickets at the same time and the flight was half full. what are some of these airlines thinking when they assign seats?

Wingo changed departure time 3 times and kept us moving from one gate to a different one. A 1 one flight took me more than 8 hours. Don't fly wit Wingo, the worst experience ever

Nothing the vendor services and overall process was not an experience I would ever want to revisit again .

Pros: "Crew was great and friendly- good meals on long flights- best airline!"
Cons: "everything was great"

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

The usb plugs for charging your phone didn’t work, the seats were coarse and hard. Not very comfortable. No inflight WiFi

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

No food, terms when selling are not clear. To pricy for the service in general

Avianca is not what it used to be. So disappointing

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Everything you need to know for your flight from Medellín to Panama City

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.