PTY - MDE

$124 Find Cheap Flights from Panama City to Medellín

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Medellín departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Medellín Jose Maria Cordova Intl Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Medellín, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Medellín, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$237
Overall average: $178
Copa Airlines
Fri 2/20Tue 2/24
PTY - MDE • Non-stop
Cheapest one-way
$124
Typical prices: $74-$137
Copa Airlines
Mon 2/23
PTY - MDE • Non-stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Avianca's Classic fare includes a free checked bag.
Copa's B737 fleet reduces delays and cancellations.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Copa Airlines
Cheapest • from $237 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
May
Cheapest • 15% price drop
January
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Medellín!
Flight Deals
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Flight Deals

Cheap Flights from Panama City to Medellín (PTY-MDE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Medellín that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Medellín

Fri, Feb 20 - Tue, Feb 24
Copa Airlines Logo
8:28 am - 9:51 am
PTY
-
MDE
1h 23mnonstop
Copa Airlines Logo
10:46 am - 12:14 pm
MDE
-
PTY
1h 28mnonstop
$237Copa Airlines
Fri, Mar 6 - Sun, Mar 15
Copa Airlines Logo
9:34 am - 10:56 am
PTY
-
MDE
1h 22mnonstop
Copa Airlines Logo
6:25 am - 7:49 am
MDE
-
PTY
1h 24mnonstop
$238Copa Airlines
Thu, Feb 19 - Fri, Mar 13
Copa Airlines Logo
6:35 pm - 8:00 pm
PTY
-
MDE
1h 25mnonstop
Copa Airlines Logo
6:20 pm - 7:48 pm
MDE
-
PTY
1h 28mnonstop
$247Copa Airlines
Thu, Feb 19 - Sat, Feb 28
Copa Airlines Logo
6:35 pm - 8:00 pm
PTY
-
MDE
1h 25mnonstop
Copa Airlines Logo
9:17 am - 10:44 am
MDE
-
PTY
1h 27mnonstop
$248Copa Airlines
Tue, Feb 17 - Thu, Feb 19
Avianca Logo
2:55 pm - 6:55 pm
PTY
-
MDE
4h 00m
1 stop
Avianca Logo
4:45 am - 8:50 am
MDE
-
PTY
4h 05m
1 stop
$249Avianca
Thu, Apr 2 - Mon, Apr 6
Copa Airlines Logo
9:31 am - 10:55 am
PTY
-
MDE
1h 24mnonstop
Copa Airlines Logo
5:00 am - 6:28 am
MDE
-
PTY
1h 28mnonstop
$252Copa Airlines
Wed, Apr 29 - Tue, May 5
Copa Airlines Logo
9:31 am - 10:55 am
PTY
-
MDE
1h 24mnonstop
Copa Airlines Logo
6:25 am - 7:53 am
MDE
-
PTY
1h 28mnonstop
$253Copa Airlines
Thu, Feb 19 - Mon, Feb 23
Copa Airlines Logo
6:35 pm - 8:00 pm
PTY
-
MDE
1h 25mnonstop
Copa Airlines Logo
6:20 pm - 7:48 pm
MDE
-
PTY
1h 28mnonstop
$258Copa Airlines
Thu, Feb 19 - Mon, Feb 23
Copa Airlines Logo
6:35 pm - 8:00 pm
PTY
-
MDE
1h 25mnonstop
Copa Airlines Logo
6:20 pm - 7:48 pm
MDE
-
PTY
1h 28mnonstop
$259Copa Airlines
Fri, Feb 27 - Sun, Mar 1
Avianca Logo
9:45 am - 3:30 pm
PTY
-
MDE
5h 45m
1 stop
Avianca Logo
9:00 pm - 1:00 am
MDE
-
PTY
4h 00m
1 stop
$261Avianca
Booking Insights

KAYAK's insights & trends for Panama City to Medellín flights

Get data-powered insights and trends into flights from Panama City to Medellín to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to Medellín?

The average price of all round-trip flights from Panama City to Medellín Jose Maria Cordova Intl Airport clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Medellín on a Monday, as we generally find the cheapest rates on that day for this route. On the other hand, Saturday is the most expensive day to fly from Panama City to Medellín. For your return ticket, we recommend flying on a Friday and avoiding Tuesdays for the best deals.

What is the cheapest month to fly from Panama City to Medellín Jose Maria Cordova Intl Airport?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Medellín Jose Maria Cordova Intl Airport, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Medellín Jose Maria Cordova Intl Airport is May, where tickets cost $152 (return) on average. On the other hand, the most expensive months are November and December, where the average cost of round-trip tickets is $217 and $201 respectively.

Can I save money by flying with a layover from Panama City to Medellín Jose Maria Cordova Intl Airport?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $286 on average.

How far in advance should I book a flight from Panama City to Medellín Jose Maria Cordova Intl Airport?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to Medellín Jose Maria Cordova Intl Airport, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to Medellín Jose Maria Cordova Intl Airport, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 10 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to Medellín

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on Copa Airlines

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Mark Chesnut

Mark Chesnut

Expert on Avianca

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Good to know

Low seasonJuly
Cheapest flight$124
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly with an average 10% increase in price.
Flight from Panama City to Medellín

When to book flights from Panama City to Medellín

Are your dates flexible? Find out the best times to travel from Panama City to Medellín based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Panama City to Medellín flights

  • What airlines operate flights from Panama City to Medellín?

    Several airlines operate flights between Panama City and Medellín. Some commonly used carriers for this route include Copa Airlines, Avianca, and Viva Air Colombia. Copa Airlines is Panama's national carrier and offers frequent flights between the two cities. Avianca is a major Colombian airline that also provides regular service on this route. Viva Air Colombia is a low-cost carrier that offers affordable options for travelers.

  • Can you rent a car at José María Córdova International Airport (MDE) after your flight from Panama City to Medellín?

    Yes, it is possible to rent a car at José María Córdova International Airport (MDE) after your flight from Panama City to Medellín. The airport has several car rental companies available for passengers to choose from. Some of the well-known car rental companies operating at MDE include Avis, Hertz, Budget, Enterprise, and SIXT. These companies offer a range of vehicles to suit different needs and preferences, and passengers can make arrangements to rent a car upon arrival at the airport.

  • Are there any visa requirements for US citizens traveling from Panama City to Medellín?

    US citizens do not typically require a visa to travel to Colombia, including Medellín, for tourism purposes. However, it is essential to have a valid passport with at least six months of remaining validity. Additionally, travelers may be required to show proof of return or onward travel, as well as proof of sufficient funds for their stay.

  • What Copa Airlines amenities are available on flights from Panama City to Medellín?

    On flights from Panama City to Medellín operated by Copa Airlines, passengers can enjoy various amenities. The airline typically offers complimentary snacks and beverages, including alcoholic beverages on select flights. Additionally, passengers have access to in-flight entertainment which may include movies, TV shows, music, and games provided through personal screens or overhead monitors.

  • What is the cheapest flight from Panama City to Medellín Jose Maria Cordova Intl Airport?

    In the last 3 days, the lowest price for a flight from Panama City to Medellín Jose Maria Cordova Intl Airport was $124 for a one-way ticket and $237 for a round-trip.

  • Do I need a passport to fly between Panama City and Medellín?

    A passport is required to fly from Panama City to Medellín.

  • Which airlines offer Wi-Fi service onboard planes from Panama City to Medellín?

    Only Iberia offers inflight Wi-Fi service on the Panama City to Medellín flight route.

  • Which aircraft models fly most regularly from Panama City to Medellín?

    The Boeing 737-800 is the aircraft model that flies most regularly on the Panama City to Medellín flight route.

  • Which airline alliances offer flights from Panama City to Medellín?

    Star Alliance is the only airline alliance operating flights between Panama City and Medellín.

  • On which days can I fly direct from Panama City to Medellín?

    There are nonstop flights from Panama City to Medellín on a daily basis.

  • Which is the best airline for flights from Panama City to Medellín, Copa Airlines or Wingo?

    The two airlines most popular with KAYAK users for flights from Panama City to Medellín are Copa Airlines and Wingo. With an average price for the route of $264 and an overall rating of 7.5, Copa Airlines is the most popular choice. Wingo is also a great choice for the route, with an average price of $162 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to Medellín?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Medellín.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Medellín?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Medellín from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Medellín?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Medellín with an airline and back to Panama City with another airline. Booking your flights between Panama City and MDE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Medellín?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Medellín from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to Medellín Jose Maria Cordova Intl Airport

  • Looking for a cheap flight? 25% of our users found flights on this route for $152 or less one-way and $286 or less round-trip.
  • Copa Airlines typically offers kid-friendly policies for passengers on flights from Panama City to Medellín. They provide services to accommodate families traveling with infants or young children, including priority boarding and assistance with strollers. The airline also offers special children's meals on board to cater to their dietary needs.
  • Depending on the airline and route you choose, you may encounter layovers during your journey from Panama City to Medellín. Common layover locations for specific airlines on this route include Bogotá (if flying with Avianca), or no layovers if you opt for a non-stop flight. Consider the duration and location of layovers when selecting your flight to plan your travel time accordingly.
  • Copa Airlines generally allows passengers to travel with small pets in the cabin for flights from Panama City to Medellín. The combined weight of the pet and carrier should not exceed 20 lbs.
  • Copa Airlines has disability policies in place to ensure a comfortable and accommodating experience for passengers traveling from Panama City to Medellín. The airline provides assistance for passengers with disabilities, including wheelchair accessibility, priority boarding, and dedicated support throughout the journey. Passengers requiring special assistance are encouraged to inform the airline at the time of booking or at least 48 hours before the flight.
  • Research and plan your transportation options from the airport in Medellín to your accommodation. Consider pre-booking a taxi or arranging for a shuttle service to ensure a smooth and hassle-free transfer. Familiarize yourself with the local transportation options, such as taxis, public buses, or private car services to make an informed decision.

Prefer to fly direct from Panama City to Medellín?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl.
Find which airlines fly direct from Panama City Tocumen Intl Airport to Medellín Jose Maria Cordova Intl Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to Medellín Jose Maria Cordova Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

Medellín Jose Maria Cordova Intl to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top 3 airlines serving from Panama City to Medellín

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Medellín. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Medellín? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1556 reviews
7.8Boarding
7.4Comfort
6.8Food
8.1Crew
6.8Entertainment
Airline reviews

A lot things happened in this trip.The fly should be less stress.

6.0 GoodIrma, Jan 2026
PTY - MIA
Read more Copa Airlines reviews

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Some of the Air hostesses are not that friendly. Need improvement

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

Very happy with my flight. I would definitely recommend it.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

Delay at the airport was not clearly communicated. No announcements were made and since we are foreigners it was very hard to know what was happening at the Wingo gate.

That they were on tike but, They charge again for baggage while we already paid when we buy our tickets

Perfect for a very low cost flight. In time, safety perfect, and of course no service, just what you effectivement !

Delayed three hours and they knew it but didn’t say anything upon checking in

Cumple con su función, transportar, no incluye comida a menos que se pague un valor adicional y así mismo con los asientos y demás, brindan precios económicos pero tratan de compensarlo cobrando por todo lo demás, si desean un viaje económico y que no dure más de 3 horas el vuelo, recomendando

i was seated apart from my girlfriend even though I bought the tickets at the same time and the flight was half full. what are some of these airlines thinking when they assign seats?

Wingo changed departure time 3 times and kept us moving from one gate to a different one. A 1 one flight took me more than 8 hours. Don't fly wit Wingo, the worst experience ever

Nothing the vendor services and overall process was not an experience I would ever want to revisit again .

Pros: "Crew was great and friendly- good meals on long flights- best airline!"
Cons: "everything was great"

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

only a bag of chips and a bottle of water in business class was served

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Everything you need to know for your flight from Panama City to Medellín

Information on your arrival and departure airports