MFR - DSM

$275 Find Cheap Flights from Medford to Des Moines - Compare and Save

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medford to Des Moines departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$275
Allegiant Air
Thu 8/6Thu 8/13
MFR - DSM • 1 stop
Top airlines
Allegiant Air
Cheapest • from $275 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Medford and Des Moines. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Phoenix (PHX)
Cheapest • Avg $501 (round-trip)
Denver (DEN)
Shortest trip • 5h 42m (one-way)
Insights
Insights
Insights
Insights
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We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medford to Des Moines (MFR-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medford to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medford to Des Moines

Thu, Aug 6 - Thu, Aug 13
Allegiant Air Logo
9:38 pm - 8:31 pm
MFR
-
DSM
20h 53m
1 stop
Allegiant Air Logo
9:44 pm - 2:48 pm
DSM
-
MFR
19h 04m
1 stop
$275Allegiant Air
Thu, Aug 6 - Wed, Aug 12
Multiple Airlines Logo
9:38 pm - 8:31 pm
MFR
-
DSM
20h 53m
1 stop
Multiple Airlines Logo
2:19 pm - 8:48 pm
DSM
-
MFR
32h 29m
2 stops
$337Multiple Airlines
Thu, Aug 6 - Thu, Aug 13
Multiple Airlines Logo
9:38 pm - 8:31 pm
MFR
-
DSM
20h 53m
1 stop
Multiple Airlines Logo
9:44 pm - 8:27 pm
DSM
-
MFR
24h 43m
2 stops
$353Multiple Airlines
Thu, Sep 10 - Tue, Sep 22
American Airlines Logo
1:27 pm - 11:59 pm
MFR
-
DSM
8h 32m
1 stop
American Airlines Logo
2:17 pm - 7:11 pm
DSM
-
MFR
6h 54m
1 stop
$429American Airlines
Tue, Aug 4 - Wed, Aug 12
American Airlines Logo
1:23 pm - 11:48 pm
MFR
-
DSM
8h 25m
1 stop
American Airlines Logo
2:39 pm - 7:20 pm
DSM
-
MFR
6h 41m
1 stop
$469American Airlines
Thu, Sep 10 - Tue, Sep 22
American Airlines Logo
1:27 pm - 11:59 pm
MFR
-
DSM
8h 32m
1 stop
American Airlines Logo
6:41 am - 7:11 pm
DSM
-
MFR
14h 30m
2 stops
$484American Airlines
Thu, Oct 8 - Mon, Oct 12
United Airlines Logo
5:00 am - 12:31 pm
MFR
-
DSM
5h 31m
1 stop
United Airlines Logo
5:22 pm - 9:14 pm
DSM
-
MFR
5h 52m
1 stop
$486United Airlines
Thu, Aug 6 - Wed, Aug 12
Delta Logo
5:28 pm - 10:18 am
MFR
-
DSM
14h 50m
2 stops
Delta Logo
5:56 pm - 11:55 pm
DSM
-
MFR
7h 59m
2 stops
$497Delta
Fri, Jun 26 - Tue, Jun 30
United Airlines Logo
6:35 pm - 10:27 am
MFR
-
DSM
13h 52m
2 stops
United Airlines Logo
11:23 am - 10:59 pm
DSM
-
MFR
13h 36m
2 stops
$499United Airlines
Tue, Aug 4 - Tue, Aug 11
American Airlines Logo
1:23 pm - 11:48 pm
MFR
-
DSM
8h 25m
1 stop
American Airlines Logo
2:39 pm - 7:20 pm
DSM
-
MFR
6h 41m
1 stop
$519American Airlines
Booking Insights

KAYAK's insights & trends for Medford to Des Moines flights

Get data-powered insights and trends into flights from Medford to Des Moines to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Medford to Des Moines?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Medford to Des Moines were found on Allegiant Air ($275) and American Airlines ($429).

Find deals

Good to know

Cheapest flight$275
Flight from Medford to Des Moines

When to book flights from Medford to Des Moines

Are your dates flexible? Find out the best times to travel from Medford to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Medford to Des Moines

  • What is the cheapest flight from Medford to Des Moines?

    In the last 5 days, the lowest price for a flight from Medford to Des Moines was $275 for a round-trip ticket.

  • Do I need a passport to fly between Medford and Des Moines?

    No

  • Which airports will I be using when flying from Medford to Des Moines?

    When flying out of Medford you will be using Medford. You will be landing at Des Moines, also known as Des Moines.

  • Which aircraft models fly most regularly from Medford to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Medford to Des Moines?

    Star Alliance is the only airline alliance operating flights between Medford and Des Moines.

  • How does KAYAK find such low prices on flights from Medford to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medford to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medford to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Medford is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medford to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Medford with another airline. Booking your flights between Medford and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medford to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Medford up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Medford to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Medford to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medford to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9830 reviews
7.1Entertainment
7.3Comfort
8.1Crew
6.6Food
7.7Boarding
Airline reviews

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

2.0 MediocreAnonymous, Jun 2026
ORD - BHM
Read more United Airlines reviews

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

The entertainment is a bit limited, it would be better if they added some games to play besides the movies and tv shows. But the seats are comfortable and the crew is polite

This planes staff was top tier. Everything went great and had a great flight home.

Food was great. Staff was phenomenal. Seats were a bit hard and could use a lot more entertainment options as far as movies to choose from. WiFi was good. Overall great trip.

This was an overnight flight, and in the morning they did know coffee service. How you can throw passengers in a San Francisco airport at 5:40 a.m. in the morning and not giving them Coffee is a crime.

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

The pilot had to extend the flight time from san antonio to Houston to burn off fuel. This caused a lot of unnecessary stress since we had a tight connection to Aruba. And with no other flights going to Aruba we were worried about spending a night in Houston. We had to to run to our connection because of the flight crews mistake. Not happy.

Service was professional and quick. Premium economy seat was comfortable given the class

I'm a United 1K member and have ben for 10 years. The gate agent had no control over the boarding process and had us passengers queued for hours as delays were announced. On the plane, the overhead air nozzle was broken so col over was powering through on me and the passenger next to me. Not a great experience for a million miler on United. Feel free to contact me. Josh Smigel - DM426089

Like: departed and arrived on time. Unlike: Food options for purchase allways bad, 1 of 2 of the crew members not very friendly at all. Seats and leg room aweful. At this point I am thinking on switching to AA.

Everything you need to know for your flight from Medford to Des Moines

Information on your arrival and departure airports

Medford (MFR)
Des Moines (DSM)