MFR - DSM

$409 Find Cheap Flights from Medford to Des Moines

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medford to Des Moines departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Des Moines, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$409
United Airlines
Wed 4/15Sat 4/18
MFR - DSM • 1 stop
Cheapest one-way
$562
Multiple Airlines
Sun 3/22
MFR - DSM • 2 stops
Top airlines
Cheapest • from $409 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Medford and Des Moines. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $475 (round-trip)
Shortest trip • 5h 52m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medford to Des Moines (MFR-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medford to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medford to Des Moines

Wed, Apr 15 - Sat, Apr 18
United Airlines Logo
12:50 pm - 8:34 pm
MFR
-
DSM
5h 44m
1 stop
United Airlines Logo
9:00 am - 1:16 pm
DSM
-
MFR
6h 16m
1 stop
$409United Airlines
Wed, Apr 15 - Sat, Apr 18
United Airlines Logo
6:31 pm - 10:44 am
MFR
-
DSM
14h 13m
2 stops
United Airlines Logo
5:17 pm - 9:38 pm
DSM
-
MFR
6h 21m
1 stop
$414United Airlines
Wed, Apr 15 - Sat, Apr 18
United Airlines Logo
6:31 pm - 10:44 am
MFR
-
DSM
14h 13m
2 stops
United Airlines Logo
1:10 pm - 11:14 pm
DSM
-
MFR
12h 04m
2 stops
$419United Airlines
Tue, Apr 7 - Mon, Apr 13
United Airlines Logo
5:00 am - 12:47 pm
MFR
-
DSM
5h 47m
1 stop
United Airlines Logo
5:17 pm - 9:37 pm
DSM
-
MFR
6h 20m
1 stop
$429United Airlines
Tue, Apr 14 - Sat, Apr 18
United Airlines Logo
12:50 pm - 8:34 pm
MFR
-
DSM
5h 44m
1 stop
United Airlines Logo
1:10 pm - 11:14 pm
DSM
-
MFR
12h 04m
2 stops
$434United Airlines
Tue, Apr 14 - Sat, Apr 18
United Airlines Logo
6:00 am - 4:10 pm
MFR
-
DSM
8h 10m
2 stops
United Airlines Logo
1:32 pm - 11:14 pm
DSM
-
MFR
11h 42m
2 stops
$439United Airlines
Wed, May 20 - Wed, May 27
United Airlines Logo
6:36 pm - 10:27 am
MFR
-
DSM
13h 51m
2 stops
United Airlines Logo
5:17 pm - 9:16 pm
DSM
-
MFR
5h 59m
1 stop
$464United Airlines
Tue, Apr 7 - Mon, Apr 13
United Airlines Logo
6:00 am - 4:10 pm
MFR
-
DSM
8h 10m
2 stops
United Airlines Logo
5:17 pm - 9:37 pm
DSM
-
MFR
6h 20m
1 stop
$469United Airlines
Tue, Apr 7 - Mon, Apr 13
United Airlines Logo
2:12 pm - 12:47 pm
MFR
-
DSM
20h 35m
3 stops
United Airlines Logo
5:17 pm - 9:37 pm
DSM
-
MFR
6h 20m
1 stop
$477United Airlines
Tue, Apr 14 - Sat, Apr 18
United Airlines Logo
5:00 am - 12:47 pm
MFR
-
DSM
5h 47m
1 stop
United Airlines Logo
5:17 pm - 9:38 pm
DSM
-
MFR
6h 21m
1 stop
$479United Airlines
Booking Insights

KAYAK's insights & trends for Medford to Des Moines flights

Get data-powered insights and trends into flights from Medford to Des Moines to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Medford to Des Moines?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Medford to Des Moines were found on United Airlines ($409) and American Airlines ($669).

Good to know

Cheapest flight$409
Flight from Medford to Des Moines

When to book flights from Medford to Des Moines

Are your dates flexible? Find out the best times to travel from Medford to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Medford to Des Moines

  • What is the cheapest flight from Medford to Des Moines?

    In the last 3 days, the lowest price for a flight from Medford to Des Moines was $562 for a one-way ticket and $409 for a round-trip.

  • Do I need a passport to fly between Medford and Des Moines?

    No

  • Which airports will I be using when flying from Medford to Des Moines?

    When flying out of Medford you will be using Medford. You will be landing at Des Moines, also known as Des Moines.

  • Which aircraft models fly most regularly from Medford to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Medford to Des Moines?

    Star Alliance is the only airline alliance operating flights between Medford and Des Moines.

  • How does KAYAK find such low prices on flights from Medford to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medford to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medford to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Medford is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medford to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Medford with another airline. Booking your flights between Medford and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medford to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Medford up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Medford to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Medford to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medford to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9428 reviews
6.6Food
7.3Comfort
8.1Crew
7.7Boarding
7.1Entertainment
Airline reviews

Both my flight where delayed Had 25min to make it to my transfer flight

4.0 OkayAnonymous, Mar 2026
BGR - EWR
Read more United Airlines reviews

Both my flight where delayed Had 25min to make it to my transfer flight

Everything was on time and service on the flight was great!

Wifi Bluetooth features for watching in flight movie was horrible. Screen kept blacking out no connection of sound although it said connected. Other than that smooth trip .

The travel company that you have on your site did me so wrong. I don’t know how it happened, but they put my son‘s name on my plane ticket flying to Vietnam. Along with his birthday. They would not have let me fly from Fort Myers to Ho Chi Minh City. I don’t think that I can ever use your service again. I typed my information into the browser along with my passport number and four days before I’m leaving I have to quickly search another ticket to fly out here.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

The flight was delayed so we were dead tired, and after that the turbulence was horrible. I was very scared.

It’s always a great time flying with united airlines.

Good flight. Efficient boarding and competent flight crew. No problems until we arrived at our destination gate. We were early so there was an aircraft at the gate that had to move before we could pull in. Then, due to the type of aircraft we flew, the cabin door could not be opened until some luggage from the cargo bay was offloaded to preserve center of gravity characteristics. So, that further delayed deplaning. Despite being 20 minutes early on landing, we ended up being 5 to 10 minutes late after all the delays.

Everything went well except the turbulence what no one have a control of but pilot and crew handled very good!

There was no WiFi available, there were mechanical problems with the plane and we landed at C 124, then the gate was switched to A 26, then all the way back to C126! For a 75 yo woman traveling alone, this was a difficult journey, indeed!

Everything you need to know for your flight from Medford to Des Moines

Information on your arrival and departure airports