MFR - GSP

$589 Find Cheap Flights from Medford to Greenville

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medford to Greenville departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Greenville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Greenville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to Greenville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$589
Delta
Thu 6/4Tue 6/9
MFR - GSP • 2 stops
Top airlines
Cheapest • from $589 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Medford and Greenville. You'll need at least 1 connection.
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We hope you love your trip to Greenville!
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Booking Insights
Flight Deals

Cheap Flights from Medford to Greenville (MFR-GSP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medford to Greenville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medford to Greenville

Thu, Jun 4 - Tue, Jun 9
Delta Logo
6:15 am - 9:38 pm
MFR
-
GSP
12h 23m
2 stops
Delta Logo
5:44 am - 1:01 pm
GSP
-
MFR
10h 17m
2 stops
$589Delta
Thu, Jun 4 - Tue, Jun 9
Delta Logo
6:15 am - 9:38 pm
MFR
-
GSP
12h 23m
2 stops
Delta Logo
5:44 am - 1:01 pm
GSP
-
MFR
10h 17m
2 stops
$629Delta
Thu, Jun 4 - Tue, Jun 9
United Airlines Logo
5:00 am - 3:19 pm
MFR
-
GSP
7h 19m
1 stop
United Airlines Logo
4:15 pm - 9:16 pm
GSP
-
MFR
8h 01m
1 stop
$668United Airlines
Thu, Jun 4 - Tue, Jun 9
United Airlines Logo
5:00 am - 3:19 pm
MFR
-
GSP
7h 19m
1 stop
United Airlines Logo
4:15 pm - 9:16 pm
GSP
-
MFR
8h 01m
1 stop
$679United Airlines
Thu, Jun 4 - Tue, Jun 9
American Airlines Logo
5:15 am - 7:24 pm
MFR
-
GSP
11h 09m
2 stops
American Airlines Logo
5:15 am - 12:50 pm
GSP
-
MFR
10h 35m
2 stops
$696American Airlines
Mon, May 11 - Mon, May 18
United Airlines Logo
6:36 pm - 9:58 am
MFR
-
GSP
12h 22m
2 stops
United Airlines Logo
4:35 pm - 9:31 pm
GSP
-
MFR
7h 56m
1 stop
$708United Airlines
Thu, Jun 4 - Tue, Jun 9
United Airlines Logo
5:00 am - 3:19 pm
MFR
-
GSP
7h 19m
1 stop
United Airlines Logo
7:40 pm - 12:04 pm
GSP
-
MFR
19h 24m
2 stops
$721United Airlines
Thu, Jun 4 - Tue, Jun 9
American Airlines Logo
5:15 am - 7:24 pm
MFR
-
GSP
11h 09m
2 stops
American Airlines Logo
5:15 am - 12:50 pm
GSP
-
MFR
10h 35m
2 stops
$728American Airlines
Thu, Jun 4 - Tue, Jun 9
United Airlines Logo
5:00 am - 3:19 pm
MFR
-
GSP
7h 19m
1 stop
United Airlines Logo
4:15 pm - 1:05 pm
GSP
-
MFR
23h 50m
1 stop
$752United Airlines
Sun, Jun 7 - Sat, Jun 13
United Airlines Logo
5:00 am - 3:19 pm
MFR
-
GSP
7h 19m
1 stop
United Airlines Logo
4:15 pm - 9:17 pm
GSP
-
MFR
8h 02m
1 stop
$880United Airlines
Booking Insights

KAYAK's insights & trends for Medford to Greenville flights

Get data-powered insights and trends into flights from Medford to Greenville to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Medford to Greenville?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Medford to Greenville were found on Delta ($589) and United Airlines ($668).

Good to know

Cheapest flight$589
Flight from Medford to Greenville

When to book flights from Medford to Greenville

Are your dates flexible? Find out the best times to travel from Medford to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Medford to Greenville

  • What is the cheapest flight from Medford to Greenville?

    In the last 3 days, the lowest price for a flight from Medford to Greenville was $589 for a round-trip ticket.

  • Do I need a passport to fly between Medford and Greenville?

    A passport is not required to fly from Medford to Greenville.

  • Which airports will I be using when flying from Medford to Greenville?

    When flying out of Medford you will be using Medford. You will be landing at Greenville, also known as Greenville.

  • Which aircraft models fly most regularly from Medford to Greenville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Medford to Greenville?

    Star Alliance, and SkyTeam are the airline alliances operating flights between Medford and Greenville, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Medford to Greenville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Medford to Greenville are Delta and United Airlines. With an average price for the route of $369 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $683 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Medford to Greenville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medford to Greenville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medford to Greenville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Greenville from Medford is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medford to Greenville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Greenville with an airline and back to Medford with another airline. Booking your flights between Medford and GSP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medford to Greenville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Greenville from Medford up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Medford to Greenville

 
See real verified KAYAK customer reviews for airlines flying from Medford to Greenville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medford to Greenville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8404 reviews
7.8Entertainment
8.1Boarding
7.2Food
8.5Crew
7.9Comfort
Airline reviews

The tray table was broken and the food was terrible.

4.0 OkayJeremy, Apr 2026
BNA - BOS
Read more Delta reviews

The tray table was broken and the food was terrible.

The gentleman at the gate I think his name is RIE was exceptional

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

One of the flight attendants was a little cranky. I appreciated the free wifi and plug to charge my laptop

No entertainment. Plane was so small had to pink tag a carry on ive used for 20 years easily on board. The fact the flight got in at midnight, had to wait for crew in fort wayne to allow the plane to approach the gate, THEN had to wait for bag on jet bridge made experience irritating at best.

Crew was great. Near on time departure and early arrival. Snacks are always meh. Not a fan of the "pay for everything including miles " proposal unless base flight rate going to be 100 bucks.

Would have been better if there was a nonstop flight from Tampa to Norfolk or Tampa to New Port News.

Overall Good! The weather delayed our takeoff from Atlanta and our arrival in Miami! If Mother Nature can mess up a flight she will do it every time!

The flight was smooth, the crew was great but the plane was quite old

Everything was great until I lost my water bottle and they can’t seem to locate it. I know I left it on the plane though.

It was a red-eye, but the flight felt surprisingly quick. The seats were very comfortable, and that made resting much easier. I also want to thank the gentleman seated next to me, who graciously moved so my mom could sit beside me. We slept almost the entire way. The cabin crew was respectful in not disturbing us, while also being courteous and professional throughout. Thank you, United.

Packed in plane small uncomfortable seats elbow to elbow nobody wants to be in that situation for the money they paid

Overall flight was ok. Flight attendant was receptive to assisting passengers with tight connections.

Checking in united could not figure out my star alliance gold. Baggage did not get marked priority and didn't receive boarding passes. When got to SFO lounge personal fixed everything Immediately

Very comfortable flight, snacks and drinks were good, good communication from crew. Could have used a little more information on timing of boarding for group 5

Great flight. Got to watch a movie. Smooth flight and early arrival at ORD.

This was the first flight in the morning. We boarded fine. The cabin door was closed and we were ready to go. We were notified by the Captain that ATC issued and ground stop for 40 minutes. So, without even pushing back from the gate, we were already 40 minutes late. We actually were released to push-back and taxi at 30 minutes. But, some passengers had tight connections and were not going to make their connections. Some passengers asked about the delay and the effect on the connections and were told by the cabin attendant that all flights will be delayed and so they should be OK. However, that was not true. My connecting flight was on time and I arrived at IAH with 21 minutes to make my connection. I did and I'm happy about that, but the flight crew should not have given assurances to the passengers who might have missed their connections.

Poor communication, flight was delayed for preventable reasons. I missed my connection.

It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.

After arriving in Chicago, we were taxiing for 1.5 hours with infrequent and untruthful updates about the amount of time it would take to arrive at the gate. Minimally, the team could have provided timing expectations that were more truthful, especially one their original expectations were not met.

Everything you need to know for your flight from Medford to Greenville

Information on your arrival and departure airports