$235 Find Cheap Flights from Medford to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medford to South Carolina departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to South Carolina, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flights Deals
Useful Info
Flights Deals

Best South Carolina Flight Deals from Medford

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston3 stops$399
Greenville
Greenville2 stops$595
Columbia
Columbia2 stops$364
Charleston
Charleston3 stops$399
Greenville
Greenville2 stops$595
Columbia
Columbia2 stops$364

Cheap Flights from Medford to South Carolina (MFR-USSC)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medford to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medford to South Carolina

Thu, May 29 - Mon, Jun 2
Delta Logo
5:10 pm - 9:23 amMFR-CAE
13h 13m2 stops
Delta Logo
5:55 pm - 11:52 pmCAE-MFR
8h 57m2 stops
$364Delta
Find Deal
Fri, May 30 - Tue, Jun 3
United Airlines Logo
5:00 am - 3:01 pmMFR-CLT
7h 01m1 stop
United Airlines Logo
8:40 am - 1:07 pmCLT-MFR
7h 27m1 stop
$404United Airlines
Find Deal
Fri, May 30 - Tue, Jun 3
United Airlines Logo
1:05 pm - 10:45 pmMFR-CLT
6h 40m1 stop
United Airlines Logo
11:00 am - 8:53 pmCLT-MFR
12h 53m2 stops
$409United Airlines
Find Deal
Fri, May 30 - Tue, Jun 3
United Airlines Logo
6:00 am - 9:44 pmMFR-CLT
12h 44m2 stops
United Airlines Logo
6:00 am - 1:07 pmCLT-MFR
10h 07m2 stops
$414United Airlines
Find Deal
Sun, Jul 20 - Sun, Jul 27
 Logo
9:51 pm - 11:58 amMFR-CAE
35h 07m2 stops
 Logo
2:59 pm - 2:40 pmCAE-MFR
26h 41m2 stops
Thu, May 29 - Mon, Jun 2
United Airlines Logo
2:12 pm - 9:59 amMFR-CAE
16h 47m3 stops
United Airlines Logo
10:34 am - 10:17 pmCAE-MFR
14h 43m2 stops
$424United Airlines
Find Deal
Sun, Jul 20 - Sun, Jul 27
 Logo
4:11 pm - 11:58 amMFR-CAE
40h 47m3 stops
 Logo
2:59 pm - 2:40 pmCAE-MFR
26h 41m2 stops
Thu, May 29 - Mon, Jun 2
United Airlines Logo
2:12 pm - 9:59 amMFR-CAE
16h 47m3 stops
United Airlines Logo
7:49 pm - 10:15 pmCAE-MFR
29h 26m3 stops
$514United Airlines
Find Deal
Fri, Oct 3 - Sun, Oct 5
American Airlines Logo
7:14 am - 7:26 pmMFR-CLT
9h 12m1 stop
American Airlines Logo
11:25 am - 10:52 pmCLT-MFR
14h 27m1 stop
$620American Airlines
Find Deal
Sun, Jul 20 - Sun, Jul 27
Delta Logo
5:30 pm - 10:15 amMFR-CAE
13h 45m2 stops
Delta Logo
3:10 pm - 11:58 pmCAE-MFR
11h 48m2 stops
$729Delta
Find Deal
Useful Info

KAYAK's insights & trends for Medford to South Carolina flights

Get data-powered insights and trends into flights from Medford to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Medford to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medford to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medford to South Carolina is August, when tickets cost $379 (return) on average. On the other hand, the most expensive months are July and December, when the average cost of round-trip tickets is $762 and $671 respectively.

What’s the cheapest day of the week to fly from Medford to South Carolina?

The average price of all round-trip flights from Medford to South Carolina clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Medford to South Carolina, look for departures on Saturdays and avoid leaving on a Friday, as it's usually the priciest day. When flying back from South Carolina, Wednesday is the cheapest day to fly and Thursday is the most expensive.


Good to know

Low seasonApril
High seasonNovember
Cheapest flight$235
Best time to beat the crowds but there is an average 2% increase in price.
Most popular time to fly with an average 60% increase in price.
Flight from Medford to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Medford to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medford to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medford to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Medford to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medford to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Medford to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medford to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Medford to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the morning, when round-trip flights cost $617 on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $617.

Top 3 airlines serving from Medford to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Medford to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medford to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 10000 reviews
7.1Entertainment
7.1Food
8.5Crew
8.2Boarding
7.9Comfort
Airline reviews

Seats are still too crowded and uncomfortable on long flights like this cross country one.

8.0 ExcellentRoger, May 2025PDX - BOS
Read more Alaska Airlines reviews

Seats are still too crowded and uncomfortable on long flights like this cross country one.

Laney was very helpful. I am computer illiterate. She helped me obtain a boarding pass and preferred seat. She was warm, friendly, helpful, and smiled. I was impressed.

The actual flight I was rescheduled onto was from Seattle to Bozeman. The flight itself was fine, but due to delays/air traffic issues i spent the day hanging out at the Seattle airport and had to miss a day of work.

OUr pilot was very good and also a good landing in a very gusting Phoenix. Most important.

Boarding was quick and easy as always the crew is on their game as always I always have an enjoyable flight so I’m good.

It was alright other than the changes in the Alaska Lounge. That and the migraine I had were disappointing. Other then that everything went well.

It was a short flight so no refreshments or entertainment which was fine.

Flying in both directions across country the gate designated on my boarding pass was wrong. From w to e across the country the passenger next to me coughed the entire way.

Although both planes (flights) had mechanical issue delaying both of my flights, the crew members handled everything with ease. Both flights had the smoothest take off and landing. I opted to upgrade my seat to first class and really lucked out getting the seat at the very front of the plane. Awesome treat to myself. I really enjoyed my flight.

The staff from check-in counter to the flight crew were great. Flight was right on schedule. 10/10

Good flights. On time. They had a gluten free snack option which was nice

Take this flight once or twice a month. Just don’t cut it from the schedule.

737-800 in first class was pretty dumpy. Seat had an uncomfortable angle, storage under the seat was blocked so even my very modest backpack didn't fit, power outlet was flaky. Weird tiny seat pockets that couldn't hold a gallon ziploc bag, emesis bag missing, etc. etc. No in-flight service due to turbulence. Crew was excellent, boarding was smooth despite a full flight.

Food from the flight from Atlanta to Santiago was very poor..

Flight was delayed due to weather. Crew did a nice job of making us comfortable. No complain complaints.

Delta is my preferred airline. I've traveled with them for years. On time in most cases, good communication, easy to use app. Most planes are pretty nice. I was on a CRJ 700/900 however, which was pretty badly aged inside and needed a refresh. No infotainment, unreliable wifi, best to download before boarding or bring a book. Food choices are really just snacks on this flight, nice variety but about what you'd expect. Great staff and prompt in departure and early arrival too. Overall quite satisfied.

Crew was friendly Love the entertainment in the seat head rest.

Delta flight was on time, seats were comfortable, and crew was nice.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

The schedule to Moline changed 5 times. The gate changed 6 times. That is a pathetic way to run an airline. No wonder that no one in our company flies on United Express to or from Moline. Changes happen most of the time. I learned my lesson on this trip…never again!

The personnel were professional and friendly. The Boeing 737 Max 9 is too claustrophobic and was very warm at both airport gates, and still warm in the air.

While the staff was pleasant and helpful, the following observations are for your awareness. There was some delay on the tarmac on take off and landing. The paid lunch/food offerings were limited. Entertainment was only available on WiFi at a cost.

Flight was great. Efficient boarding. Short flight. Early arrival. Friendly flight crew. The entertainment system did not work well. Could not access it until the aircraft reached 10K feet or more. Lots of glitches.

get E+, a must for 5 hours flight if you are tall

The first flight was better in terms of the aircraft.

we were delayed going into and out of Newark Airport by 3-4 hours each way. Excuses/reasons given were misleading. Weather was cited at first when there was NO weather issue. Turns out Newark had a shortage of staff and runway construction. United knew this and should have NOT scheduled flights when they know we would be delayed so long. I will avoid United and EWR airport at all cost going forward. Delta never looked so good.

A bit rush for transit. Food and entertainment are not available

Multiple delays and not straight answer from the United team

Stewardess spilled orange juice on my clothes/seat no help no apology just threw napkins at me to clean the mess up. Not Happy.

Everything you need to know for your flight from Medford to South Carolina

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.