$309 Find Cheap Flights from Medford to South Carolina

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medford to South Carolina departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medford to South Carolina, as well as popular online travel agencies
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Cheap Flights from Medford to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$441
Greenville
Greenville2 stops$379
Columbia
Columbia2 stops$407
Charlotte
Charlotte1 stop$309
Charleston
Charleston1 stop$441
Greenville
Greenville2 stops$379
Columbia
Columbia2 stops$407
Charlotte
Charlotte1 stop$309

Book Cheap Medford to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medford to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medford to South Carolina

Sun, Dec 7 - Sat, Dec 13
Delta Logo
5:00 am - 4:20 pmMFR-CLT
8h 20m1 stop
Delta Logo
5:31 pm - 10:53 pmCLT-MFR
8h 22m1 stop
$309Delta
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Sun, Dec 7 - Sat, Dec 13
Delta Logo
5:00 am - 4:20 pmMFR-CLT
8h 20m1 stop
Delta Logo
12:44 pm - 10:53 pmCLT-MFR
13h 09m2 stops
$314Delta
Find Deal
Sun, Dec 7 - Sat, Dec 13
Delta Logo
5:23 pm - 9:18 amMFR-CLT
12h 55m2 stops
Delta Logo
12:44 pm - 10:53 pmCLT-MFR
13h 09m2 stops
$319Delta
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Mon, Nov 17 - Mon, Nov 24
Delta Logo
5:00 am - 4:17 pmMFR-CLT
8h 17m1 stop
Delta Logo
5:29 pm - 11:56 pmCLT-MFR
9h 27m1 stop
$339Delta
Find Deal
Tue, Oct 28 - Sat, Nov 1
United Airlines Logo
6:36 pm - 11:30 amMFR-GSP
13h 54m2 stops
United Airlines Logo
12:23 pm - 8:08 pmGSP-MFR
10h 45m2 stops
$379United Airlines
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Tue, Oct 28 - Sat, Nov 1
United Airlines Logo
6:36 pm - 11:30 amMFR-GSP
13h 54m2 stops
United Airlines Logo
4:17 pm - 9:14 pmGSP-MFR
7h 57m1 stop
$397United Airlines
Find Deal
Mon, Oct 27 - Fri, Oct 31
Alaska Airlines Logo
1:26 pm - 5:00 amMFR-CLT
12h 34m2 stops
Alaska Airlines Logo
2:00 pm - 12:49 pmCLT-MFR
25h 49m1 stop
$474Alaska Airlines
Find Deal
Mon, Oct 27 - Fri, Oct 31
Alaska Airlines Logo
8:45 pm - 11:37 amMFR-CLT
11h 52m2 stops
Alaska Airlines Logo
3:30 pm - 11:30 amCLT-MFR
23h 00m2 stops
$524Alaska Airlines
Find Deal
Thu, Dec 18 - Sat, Dec 27
American Airlines Logo
5:20 am - 8:39 pmMFR-GSP
12h 19m2 stops
American Airlines Logo
8:00 am - 8:20 pmGSP-MFR
15h 20m2 stops
$1,229American Airlines
Find Deal
Sat, Dec 20 - Sat, Dec 27
American Airlines Logo
3:12 pm - 8:36 amMFR-GSP
14h 24m2 stops
American Airlines Logo
8:00 am - 8:20 pmGSP-MFR
15h 20m2 stops
$1,398American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Medford to South Carolina flights

Get data-powered insights and trends into flights from Medford to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Medford to South Carolina?

The average price of all round-trip flights from Medford to South Carolina clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Medford to South Carolina, look for departures on Saturdays and avoid leaving on a Friday, as it's usually the priciest day. When flying back from South Carolina, Wednesday is the cheapest day to fly and Thursday is the most expensive.

Good to know

Low seasonJanuary
Cheapest flight$309
Best time to beat the crowds with an average 52% drop in price.
Most popular time to fly and prices are also 16% lower on average.
Flight from Medford to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Medford to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medford to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medford to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Medford to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medford to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Medford to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medford to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Medford to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the morning, when round-trip flights cost $617 on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $617.

Reviews of the top 3 airlines serving from Medford to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Medford to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medford to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 11070 reviews
7.8Comfort
7.0Entertainment
7.1Food
8.1Boarding
8.5Crew
Airline reviews

Process of checking bag, boarding, etc. was all very quick, easy, and streamlined. Only problem I had was the seating: very cramped and uncomfortable, but I suppose that’s the perils of coach. Thankfully it wasn’t a super long flight so it didn’t ruin the experience overall.

6.0 GoodAnonymous, Oct 2025PDX - MCI
Read more Alaska Airlines reviews

Process of checking bag, boarding, etc. was all very quick, easy, and streamlined. Only problem I had was the seating: very cramped and uncomfortable, but I suppose that’s the perils of coach. Thankfully it wasn’t a super long flight so it didn’t ruin the experience overall.

The boarding was confusing because the PA system at PDX was so quiet you couldn’t hear anything being said . The seats were uncomfortable. The food was pretty bad and I normally don’t mind airplane food. The flight attendants were not friendly. I learned upon check in that Hawaiian airlines had reassigned our seats of the second leg of the trip. I had confirmed and paid for special seats but they put me and my companion on standard seats in different rows. Hawaiian also did the same on my return flight after the flight times had changed. I happened to go online to check my reservation and saw the flight had changed. I gad received no notice. I saw that my confirmed seats that I had paid extra were gone. After much back and forth with the airlines they refused to correct their error. I showed them confirmation documents of my seat reservation and receipt of payment but they refused to correct the seat change or reimburse me. I had to pay $200 again to reserve the original seats. Shameful and manipulative. They basically held me hostage. If I wanted to be in that flight I had to pay up.

When I bought my tickets I up great my seats for extra $104 each seats 8A and 8B in the way back from Portland to Palm Springs they gave me the seats 15. I thought it was for round trip same seats . So I was very disappointed ☹️

One disappointment. There was a gate change from B8 to B10, they had announced it maybe 20 minutes before the boarding time, possibly less. I didn’t hear the announcement as I was listening to music on my head phones at B8. At the boarding time, I got up and asked the gal at the B8 boarding desk, why the destination sign had not changed and if the flight was delayed as there was no plane behind her through the window, she said that perhaps the flight was delayed and the screen will probably update in -5 minutes ( she apparently didn’t know the boarding gate was changed ( 2 down from our location) I put my headphones on and went back to sit down . Just before the B10 door closed, I got a phone call asking me if I was still taking the flight, I said. “Yes” but I was at the gate stated on my ticket B8, then I was informed of the gate change, I got up and ran to the gate, and down the hallway to the jet ramp. I was the last to board!! Very frustrating . I was shocked that I got no emails or text messages from Alaska informing me of a last minute change!!

The crew was the best I’ve ever had HOWEVER when we arrived in Salt Lake City there were no Alaskan Airline employees to be found so we weren’t able to leave the plane until ANOTHER airline took pity on us. How could that possible happen?

The pilot performed the smoothest landing I’ve ever experienced. What a light touch. And I’m an avid traveler!

They closed boarding too early. They made me pay extra to continue flying with them. Their customer service is non-responsive. I used to love Alaska Airlines, but they've definitely regressed.

The vibe and energy of the Alaska staff on ground in Redmond is some of the best we’ve seen!

Didn't buy food and did not use entertainment as these were not the purpose of my flight.

Website could be better with faster access to specific flight information and boarding pass once reservation is made. Not a fan of no seat selection on line. I had to consult gate agent each time to change seats on flights with lots of open seats. This cannot possibly be cost effective for airline. On plus side, Alaska seat legroom seemed larger than American. ns

On time flight. Seat comfort could be better in the Comfort section.

My issue was with TSA agents for delta airlines. My luggage got flagged. The agent was going thru another persons first. He took 20 min to go thru hers. I asked them to bring mine closer so I could sit down . They said you can go sit it will be fine. I said I am supposed to keep my eyes on my bags at all times. The agent was meticulously unwrapping 2 gifts that the lady had and then tried to re warp it. He was trying to be kind i get it but 20 min for me to stand watching him do that was ridiculous. It was 6 am and there were a ton of travelers. Mine was flagged for some air packed tea that I bought in Turkey. My previous delta flight and 2 others before didn’t flag it. Consistency would be nice. Also on the flight the window shades were down for take off and landing - I thought that was very odd I thought they had to remain open for take off and landing.

The flight was an hour and a half late departing which was inconvenient

Delay in SLC jammed us up in Chicago. Got caught up in rush hour traffic

The crew took good care of us. The flight from ATL to SFO is a longer one, and there were multiple beverage offerings. I like the 757's that Delta uses. Good airplane that is comfortable. I do wish Delta would separate Priority boarding from the better seats. I would gladly take a smaller seat in an open row than be jammed into Comfort just to get priority boarding, just to make sure I don't have to check a bag.

The flight was great. The gate location was way to far away!!!

The flight attendant in first class was beyond rude and didn't care at all about her job. AND the gate agent was even worse than the flight attendant for rudeness. She was awful.

Gate agent rushed to fill hot jetway with crowd so it took over 12 minutes to go from gate to plane. Just like a discount airline Pooly prepared cabin and third time that claim of rough air prevented any cabin service. Friends on a Southwest flight at similar time had service.

Cramped seating for me. Luckily it wasn’t a long flight

Lounge in Lagos is terrible, food on board from Lagos to Atlanta was horrible. Only bright spot the cabin crew were awesome.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

The worst landing I have ever had on a domestic flight. Thought we would lose the landing gear on landing in Newark. Then we spent 40 minutes trying to position the plane in the right place to be able to get the jet way to the plane. The plane arrived stopped. The announcer was that we were there. Everybody got up, then we were told to sit back down because they had to have us towed to a different position. We got towed and then everyone stood up and they told us we were in the wrong position to sit back down again, and then we got towed to a different position This did not happen immediately. It was 30 minutes while we wandered around a small section of the tarmac in Newark close to the gate, but apparently not close enough. Horrifying experience The CAB should be investigating that flight

Boarding was organized. Plane seats comfortable and service was attentive. Food options were good.

This was a very average flight. The seat was out of alignment so more uncomfortable than usual. The cabin felt not well maintained. But I safely got where I needed to go.

Trip was great. A wild landing in Ottawa with the wind and rain, but the pilot did a great job. Always love flying United.👍

I will never book a flight through Cheap fare. They booked me from Portland Main . And would not give me a refund, so I bought 2 tickets one for 299. From Portland Main to ORD. Then I had to buy a ticket from Oregon PDX to ORD that was another 440. So Just so you know they even told me it was there fault but no refund. Bad bussniess. I did inform United but they said they couldn't help me due to the fact I booked through Cheap Tickets. Never again. And I'm spreding the word. I let everyone know at my 50th class reunion

The internet service I paid for didn’t work at all and the flight crew was not very friendly.

Excellent experience. Starting with the agent at the Premier bag drop who noticed I was very early for my scheduled flight and offered to rebook me on an earlier flight with my seat preference. She would not let me leave the counter until she knew that all of the changes and new boarding pass showed up on my United app. At the gate, the flight boarded quickly such that we departed early and the flight was smooth. We arrived 20 minutes early at ORD and I was able to be home in time for dinner. One of the best flights I've had.

Late FA meant slow boarding. WiFi did not work. I’m a medium plus sized passenger. The seatbelt was for the first time ever barely fitting. And we delayed on the tarmac 40 min

Salina to travers city was great! But the sept 24 Tranverse city was not! Traverse city to chichago was cancelled, i went to Denver & got to Salina 6 hours later!

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