SCL - MEX

$271 Find Cheap Flights from Santiago to Mexico City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Mexico City departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Mexico City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Mexico City, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Santiago to Mexico City (SCL-MEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Mexico City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to Mexico City

Sat, Jan 24 - Tue, Feb 3
LATAM Airlines Logo
5:15 am - 1:50 pmSCL-MEX
11h 35m1 stop
LATAM Airlines Logo
7:50 pm - 7:30 amMEX-SCL
8h 40mnonstop
$485LATAM Airlines
Find Deal
Sun, Feb 1 - Tue, Feb 24
LATAM Airlines Logo
4:35 am - 1:50 pmSCL-MEX
12h 15m1 stop
LATAM Airlines Logo
4:00 pm - 2:30 pmMEX-SCL
19h 30m2 stops
$487LATAM Airlines
Find Deal
Fri, Mar 20 - Sun, Mar 22
Avianca Logo
1:35 am - 12:10 pmSCL-MEX
13h 35m1 stop
Avianca Logo
12:40 am - 3:20 pmMEX-SCL
35h 40m1 stop
$489Avianca
Find Deal
Mon, Nov 24 - Thu, Nov 27
Copa Airlines Logo
1:12 am - 7:20 pmSCL-MEX
21h 08m1 stop
Copa Airlines Logo
2:00 am - 8:21 pmMEX-SCL
15h 21m1 stop
$492Copa Airlines
Find Deal
Mon, Mar 2 - Tue, Mar 31
Copa Airlines Logo
1:17 am - 7:20 pmSCL-MEX
21h 03m1 stop
Copa Airlines Logo
5:50 am - 12:27 amMEX-SCL
15h 37m1 stop
$494Copa Airlines
Find Deal
Sat, Nov 1 - Fri, Nov 7
Copa Airlines Logo
3:23 am - 12:15 amSCL-MEX
23h 52m1 stop
Copa Airlines Logo
1:20 am - 3:43 amMEX-SCL
23h 23m1 stop
$495Copa Airlines
Find Deal
Sun, Nov 2 - Thu, Nov 13
Copa Airlines Logo
5:12 am - 12:15 amSCL-MEX
22h 03m1 stop
Copa Airlines Logo
1:20 am - 11:41 pmMEX-SCL
19h 21m1 stop
$496Copa Airlines
Find Deal
Mon, Nov 10 - Tue, Nov 18
Copa Airlines Logo
3:23 am - 7:20 pmSCL-MEX
18h 57m1 stop
Copa Airlines Logo
5:55 am - 12:06 amMEX-SCL
15h 11m1 stop
$498Copa Airlines
Find Deal
Sat, Jan 24 - Tue, Feb 3
Multiple Airlines Logo
8:15 am - 5:40 amSCL-MEX
24h 25m2 stops
Multiple Airlines Logo
7:50 pm - 7:30 amMEX-SCL
8h 40mnonstop
$500Multiple Airlines
Find Deal
Wed, Apr 1 - Fri, Apr 10
Avianca Logo
7:10 am - 12:05 pmSCL-MEX
31h 55m1 stop
Avianca Logo
12:40 am - 10:30 pmMEX-SCL
19h 50m1 stop
$509Avianca
Find Deal

Everything you should know

Our travelers' advice
AI-generated summary based on content written by travel experts
Aeromexico's AM Plus offers extra legroom in economy.
LATAM's in-flight entertainment features an 18” screen.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
LATAM Airlines
Cheapest • from $485 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
5 weeks
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 27% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 10% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$485
Overall average: $703
LATAM Airlines
Sat 1/24Tue 2/3
SCL - MEX • 1 stop
Cheapest non-stop
$499
Typical prices: $615-$928
LATAM Airlines
Fri 12/19Sat 1/3
SCL - MEX • Non-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Mexico City!
Booking Insights

KAYAK's insights & trends for Santiago to Mexico City flights

Get data-powered insights and trends into flights from Santiago to Mexico City to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santiago to Mexico City?

The average price of all round-trip flights from Santiago to Mexico City clicked on KAYAK for each day over the last 12 months.

When flying from Santiago to Mexico City, you should consider leaving on a Thursday and avoid Mondays if you are looking for the best rates. For your return to Santiago, you’ll find the best rates on Wednesdays and the most expensive ones on Fridays.

What is the cheapest month to fly from Santiago to Mexico City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to Mexico City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to Mexico City is March, where tickets cost $546 (return) on average. On the other hand, the most expensive months are January and February, where the average cost of round-trip tickets is $703 and $656 respectively.

Can I save money by flying with a layover from Santiago to Mexico City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $534, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Santiago to Mexico City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to Mexico City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to Mexico City, you should book around 5 weeks before departure, which saves you about 27% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Expert advice

Expert advice for your flight from Santiago to Mexico City

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
LATAM Airlines

LATAM's Premium Business offers 1-2-1 configuration for all-aisle access on long-haul flights.


LATAM in-flight entertainment includes an 18” touchscreen and noise-canceling headphones on long-haul flights.

Aeromexico

Aeromexico's Clase Premier offers 20” wide seats with 60” separation on Boeing 787-9.


Aeromexico's AM Plus provides extra legroom and priority boarding in economy class.

Our travel experts
Marisa Garcia

Marisa Garcia

Expert on LATAM Airlines and Aeromexico

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more

Good to know

Low seasonAugust
Cheapest flight$271
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Santiago to Mexico City

When to book flights from Santiago to Mexico City

Are your dates flexible? Find out the best times to travel from Santiago to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to Mexico City

  • What is the cheapest flight from Santiago to Mexico City?

    In the last 3 days, the lowest price for a flight from Santiago to Mexico City was $271 for a one-way ticket and $485 for a round-trip.

  • Do I need a passport to fly between Santiago and Mexico City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santiago and on arrival in Mexico City.

  • Which airports will I be using when flying from Santiago to Mexico City?

    Santiago airport is called Santiago Arturo Merino Benitez and the only airport in Mexico City is Mexico City Benito Juarez.

  • Which airlines offer Wi-Fi service onboard planes from Santiago to Mexico City?

    Only American Airlines offers inflight Wi-Fi service on the Santiago to Mexico City flight route.

  • Which aircraft models fly most regularly from Santiago to Mexico City?

    The Airbus A330 is the aircraft model that flies most regularly on the Santiago to Mexico City flight route.

  • Which airline alliances offer flights from Santiago to Mexico City?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Santiago and Mexico City, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Santiago to Mexico City?

    There are nonstop flights from Santiago to Mexico City on a daily basis.

  • Which is the best airline for flights from Santiago to Mexico City, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Santiago to Mexico City are Copa Airlines and LATAM Airlines. With an average price for the route of $579 and an overall rating of 7.6, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $707 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Santiago to Mexico City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Mexico City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Mexico City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Mexico City from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Mexico City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Mexico City with an airline and back to Santiago with another airline. Booking your flights between Santiago and MEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Mexico City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Mexico City from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santiago to Mexico City

  • Looking for a cheap flight? 25% of our users found flights on this route for $661 or less one-way and $495 or less round-trip.

Prefer to fly direct from Santiago to Mexico City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santiago Arturo Merino Benitez to Mexico City Benito Juarez.
Find which airlines fly direct from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport, which days they fly and book direct flights.

Direct departures

Santiago Arturo Merino Benitez to Mexico City Benito Juarez

Monday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Tuesday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Wednesday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Thursday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Friday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Saturday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Sunday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

See more direct flights

Direct returns

Mexico City Benito Juarez to Santiago Arturo Merino Benitez

Monday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Tuesday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Wednesday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Thursday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Friday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Saturday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Sunday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

See more direct flights

Reviews of the top 4 airlines serving from Santiago to Mexico City

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Mexico City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Mexico City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1549 reviews
8.1Crew
6.8Food
7.4Comfort
7.8Boarding
6.8Entertainment
Airline reviews

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

10.0 ExcellentSherry, Oct 2025ORD - PTY
Read more Copa Airlines reviews

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Great experience with a crew always thinking in the passenger

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

It’s a delta flight operated by LATAM. The whole ticket sale is a mess, delta changed my flight but didn’t update it in LATAM system, I couldn’t get my boarding pass, it took me hours to resolve this issue with delta. I had to change my travel plan. No apology from Delta even though it’s their fault.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

The boarding and new bag drop-off process was confusing and causing massive delays.

It was a very good flight, no entertainment is the reason for not checking that box.

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

Aeroméxico cancelled my ticket without advice AND It make a last minute mess in my intinerary, no solving my situation, bad advice and bad customer service

The ground staff were not as friendly and nice to the passengers as the air crew. Flight attendants, cockpit crew were great and very nice to everyone on board.

My flight was delayed, then I got transferred to a new flight that was also delayed- which wasn’t Aeromexico’s fault, it was because of weather conditions. Most of the crew was very nice and patient, except for one or two flight attendants who were rude. The entertainment wasn’t on, so all the screens were off.

My wife's entertainment system did not work. Payed for flight upgrade but did not receive advertised "free WiFi".

Annoying that we had to go to departures and get boarding passes. Should allow us to be booked all the way through, this is the only airline i have this problem with in MEX. Late boarding and take off

Lousy No wheelchair. As normal at Atlanta Cheap airline Cheap aero plane. - Neither entertainment nor food on a 5 hour saga

The airplane was an old airplane, seats were very uncomfortable and very little space, they changed my seat and that was no option to get back into my seat even when I was traveling a senior who required assistance.

This is not a low cost airline. Stop acting like o e.

Aeromexico crew made me check my hand luggage in the door of the plane. As soon as I reach Mexico City, I notice that my luggage was opened and 8 games of Nintendo Switch were stolen (700 dllrs value aprox) (the console was there) but the games were stolen. I am very dissapointed of Aeromexico and all the crew. Instead of being a good trip, It was a sad trip

Ok. But we arrived to a remote terminal which meant that a bus had to take us to the terminal building

Boarding, crew were excellent, food was ok and entertainment need to improve

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Luggage lost and nowhere to be found, no response from either airline regarding my bag

The seats were uncomfortable and barely reclined at all. Very little leg room despite being business class. The crew was friendly and the food was good. Had to use my own phone for in-flight entertainment.

Not what it used to be. The sale of food makes them look greedy!

No food, terms when selling are not clear. To pricy for the service in general

why did we have to go through security mid flight

The chicken that was served in business class was cold!

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Everything you need to know for your flight from Santiago to Mexico City

Information on your arrival and departure airports

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