SCL - MEX

$277 Find Cheap Flights from Santiago to Mexico City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Mexico City departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Mexico City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Mexico City, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$533
Overall average: $559
Multiple Airlines
Wed 3/4Wed 3/18
SCL - MEX • 1 stop
Cheapest non-stop
$554
Typical prices: $532-$623
LATAM Airlines
Wed 3/4Wed 3/18
SCL - MEX • Non-stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Aeromexico's AM Plus offers extra legroom in economy.
LATAM's in-flight entertainment features an 18” screen.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
LATAM Airlines
Cheapest • from $554 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
5 weeks
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 25% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 8% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Mexico City!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Santiago to Mexico City (SCL-MEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Mexico City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to Mexico City

Wed, Mar 4 - Wed, Mar 18
Multiple Airlines Logo
11:05 pm - 11:10 am
SCL
-
MEX
15h 05m
1 stop
Multiple Airlines Logo
11:10 pm - 9:55 pm
MEX
-
SCL
19h 45m
2 stops
$533Multiple Airlines
Thu, Feb 26 - Thu, Mar 5
Multiple Airlines Logo
9:05 pm - 11:10 am
SCL
-
MEX
17h 05m
1 stop
Multiple Airlines Logo
9:55 pm - 2:40 pm
MEX
-
SCL
13h 45m
1 stop
$540Multiple Airlines
Wed, Mar 4 - Wed, Mar 18
Avianca Logo
7:25 am - 3:00 am
SCL
-
MEX
22h 35m
1 stop
Avianca Logo
1:50 pm - 3:20 pm
MEX
-
SCL
22h 30m
1 stop
$549Avianca
Wed, Mar 4 - Sun, Mar 8
Avianca Logo
4:25 pm - 3:00 am
SCL
-
MEX
13h 35m
1 stop
Avianca Logo
11:10 pm - 3:20 pm
MEX
-
SCL
13h 10m
1 stop
$554Avianca
Thu, Feb 26 - Thu, Mar 5
Multiple Airlines Logo
10:15 pm - 11:10 am
SCL
-
MEX
15h 55m
1 stop
Multiple Airlines Logo
9:55 pm - 7:54 pm
MEX
-
SCL
18h 59m
2 stops
$557Multiple Airlines
Wed, Mar 4 - Wed, Apr 29
Copa Airlines Logo
5:21 am - 12:15 am
SCL
-
MEX
21h 54m
1 stop
Copa Airlines Logo
5:50 am - 5:03 am
MEX
-
SCL
21h 13m
1 stop
$567Copa Airlines
Mon, Mar 23 - Tue, Mar 31
LATAM Airlines Logo
9:00 am - 2:50 pm
SCL
-
MEX
8h 50mnonstop
LATAM Airlines Logo
8:20 pm - 7:20 am
MEX
-
SCL
8h 00mnonstop
$568LATAM Airlines
Fri, Feb 27 - Sat, Mar 7
LATAM Airlines Logo
4:35 am - 1:50 pm
SCL
-
MEX
12h 15m
1 stop
LATAM Airlines Logo
7:50 pm - 7:30 am
MEX
-
SCL
8h 40mnonstop
$569LATAM Airlines
Thu, Apr 16 - Fri, Apr 24
Copa Airlines Logo
11:25 am - 12:15 am
SCL
-
MEX
14h 50m
1 stop
Copa Airlines Logo
1:20 am - 7:23 pm
MEX
-
SCL
16h 03m
1 stop
$577Copa Airlines
Thu, Apr 9 - Tue, Apr 14
Copa Airlines Logo
11:25 am - 12:15 am
SCL
-
MEX
14h 50m
1 stop
Copa Airlines Logo
5:50 am - 2:20 am
MEX
-
SCL
18h 30m
1 stop
$587Copa Airlines
Booking Insights

KAYAK's insights & trends for Santiago to Mexico City flights

Get data-powered insights and trends into flights from Santiago to Mexico City to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santiago to Mexico City?

The average price of all round-trip flights from Santiago to Mexico City clicked on KAYAK for each day over the last 12 months.

When flying from Santiago to Mexico City, you should consider leaving on a Monday and avoid Fridays if you are looking for the best rates. For your return to Santiago, you’ll find the best rates on Tuesdays and the most expensive ones on Saturdays.

What is the cheapest month to fly from Santiago to Mexico City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to Mexico City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to Mexico City is March, where tickets cost $559 (return) on average. On the other hand, the most expensive months are January and April, where the average cost of round-trip tickets is $655 and $634 respectively.

Can I save money by flying with a layover from Santiago to Mexico City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $388, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Santiago to Mexico City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to Mexico City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to Mexico City, you should book around 5 weeks before departure, which saves you about 25% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Expert advice

Expert advice for your flight from Santiago to Mexico City

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
LATAM Airlines

LATAM's Premium Business offers 1-2-1 configuration for all-aisle access on long-haul flights.


LATAM in-flight entertainment includes an 18” touchscreen and noise-canceling headphones on long-haul flights.

Aeromexico

Aeromexico's Clase Premier offers 20” wide seats with 60” separation on Boeing 787-9.


Aeromexico's AM Plus provides extra legroom and priority boarding in economy class.

Our travel experts
Marisa Garcia

Marisa Garcia

Expert on LATAM Airlines and Aeromexico

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more

Good to know

Low seasonAugust
Cheapest flight$277
Most popular time to fly and prices are also 3% lower on average.
Flight from Santiago to Mexico City

When to book flights from Santiago to Mexico City

Are your dates flexible? Find out the best times to travel from Santiago to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to Mexico City

  • What is the cheapest flight from Santiago to Mexico City?

    In the last 3 days, the lowest price for a flight from Santiago to Mexico City was $277 for a one-way ticket and $533 for a round-trip.

  • Do I need a passport to fly between Santiago and Mexico City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santiago and on arrival in Mexico City.

  • Which airports will I be using when flying from Santiago to Mexico City?

    Santiago airport is called Santiago Arturo Merino Benitez and the only airport in Mexico City is Mexico City Benito Juarez.

  • Which airlines offer Wi-Fi service onboard planes from Santiago to Mexico City?

    Only American Airlines offers inflight Wi-Fi service on the Santiago to Mexico City flight route.

  • Which aircraft models fly most regularly from Santiago to Mexico City?

    The Airbus A330 is the aircraft model that flies most regularly on the Santiago to Mexico City flight route.

  • Which airline alliances offer flights from Santiago to Mexico City?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Santiago and Mexico City, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Santiago to Mexico City?

    There are nonstop flights from Santiago to Mexico City on a daily basis.

  • Which is the best airline for flights from Santiago to Mexico City, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Santiago to Mexico City are Copa Airlines and LATAM Airlines. With an average price for the route of $638 and an overall rating of 7.6, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $686 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Santiago to Mexico City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Mexico City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Mexico City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Mexico City from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Mexico City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Mexico City with an airline and back to Santiago with another airline. Booking your flights between Santiago and MEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Mexico City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Mexico City from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santiago to Mexico City

  • Looking for a cheap flight? 25% of our users found flights on this route for $423 or less one-way and $388 or less round-trip.

Prefer to fly direct from Santiago to Mexico City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santiago Arturo Merino Benitez to Mexico City Benito Juarez.
Find which airlines fly direct from Santiago Arturo Merino Benitez Airport to Mexico City Benito Juarez Airport, which days they fly and book direct flights.

Direct departures

Santiago Arturo Merino Benitez to Mexico City Benito Juarez

Monday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Tuesday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Wednesday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Thursday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Friday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Saturday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Sunday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

See more direct flights

Direct returns

Mexico City Benito Juarez to Santiago Arturo Merino Benitez

Monday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Tuesday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Wednesday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Thursday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Friday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Saturday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

Sunday

Aeromexico, LATAM Airlines

Aeromexico, LATAM Airlines

See more direct flights

Reviews of the top 4 airlines serving from Santiago to Mexico City

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Mexico City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Mexico City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1559 reviews
7.4Comfort
8.1Crew
6.8Food
6.8Entertainment
7.8Boarding
Airline reviews

A lot things happened in this trip.The fly should be less stress.

6.0 GoodIrma, Jan 2026
PTY - MIA
Read more Copa Airlines reviews

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Some of the Air hostesses are not that friendly. Need improvement

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor, the airline was not able to help me move flights.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

Really nice, all good, nice crew and all on time

Unfortunately I had an awful boarding experience. Our first flight with Aeromexico was fine and landed on time however it couldn’t find a gate and we were late which made us lose our connecting flight with Aeromexico. The staff handled it horribly when we explained our situation and would not led us board when we missed the boarding time by a couple minutes. The staff were extremely rude and did not attempt to even help us. Because of this incident, my husband and I missed a full day of work which negatively impacted our salary which we need. Please compensate us for the work that we missed.

It was OK. The flight is pretty long for the airlines to only offer a simple sandwich on business class. The entertainment is similar to that on other Skyteam members. Ultimately the airline lost my bag and didn’t deliver it to me until the next day after a lengthy lost baggage report.

Aeroméxico cancelled my ticket without advice AND It make a last minute mess in my intinerary, no solving my situation, bad advice and bad customer service

It was good in general. The Crew during the flight were very nice at all times.

The ground staff were not as friendly and nice to the passengers as the air crew. Flight attendants, cockpit crew were great and very nice to everyone on board.

My flight was delayed, then I got transferred to a new flight that was also delayed- which wasn’t Aeromexico’s fault, it was because of weather conditions. Most of the crew was very nice and patient, except for one or two flight attendants who were rude. The entertainment wasn’t on, so all the screens were off.

My wife's entertainment system did not work. Payed for flight upgrade but did not receive advertised "free WiFi".

Annoying that we had to go to departures and get boarding passes. Should allow us to be booked all the way through, this is the only airline i have this problem with in MEX. Late boarding and take off

Lousy No wheelchair. As normal at Atlanta Cheap airline Cheap aero plane. - Neither entertainment nor food on a 5 hour saga

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

I couldnt recline the seat. Other than that crew was very attentive and helpful. Thsnk you

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

Everything you need to know for your flight from Santiago to Mexico City

Information on your arrival and departure airports