MYR - STL

$136 Find Cheap Flights from Myrtle Beach to St. Louis - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to St. Louis departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to St. Louis, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$297
Typical prices: $368-$529
Delta
Tue 7/21Wed 7/22
MYR - STL • 1 stop
Cheapest non-stop
$321
Southwest
Sat 8/22Mon 8/24
MYR - STL • Non-stop
Nonstop flights
5 days a week
Mon, Thu, Fri, Sat, Sun
You can fly direct with Southwest. Average duration is 2h 06m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
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Top airlines
Cheapest • from $297 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
Cheapest • 41% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Myrtle Beach to St. Louis (MYR-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to St. Louis

Tue, Jul 21 - Wed, Jul 22
Delta Logo
4:16 pm - 10:15 pm
MYR
-
STL
6h 59m
1 stop
Delta Logo
9:24 am - 3:27 pm
STL
-
MYR
5h 03m
1 stop
$297Delta
Thu, Aug 27 - Mon, Aug 31
American Airlines Logo
4:23 pm - 11:42 pm
MYR
-
STL
8h 19m
1 stop
American Airlines Logo
10:22 am - 4:25 pm
STL
-
MYR
5h 03m
1 stop
$299American Airlines
Thu, Aug 27 - Tue, Sep 1
United Airlines Logo
10:23 am - 10:00 pm
MYR
-
STL
12h 37m
2 stops
United Airlines Logo
8:00 am - 2:53 pm
STL
-
MYR
5h 53m
1 stop
$304United Airlines
Tue, Jul 14 - Tue, Jul 21
Delta Logo
6:00 am - 9:43 am
MYR
-
STL
4h 43m
1 stop
Delta Logo
9:24 am - 3:27 pm
STL
-
MYR
5h 03m
1 stop
$307Delta
Wed, Sep 2 - Wed, Sep 9
Southwest Logo
8:15 am - 3:10 pm
MYR
-
STL
7h 55m
2 stops
Southwest Logo
10:45 am - 7:10 pm
STL
-
MYR
7h 25m
2 stops
$309Southwest
Sat, Oct 17 - Thu, Oct 22
Southwest Logo
2:35 pm - 9:20 pm
MYR
-
STL
7h 45m
1 stop
Southwest Logo
2:05 pm - 8:15 pm
STL
-
MYR
5h 10m
1 stop
$313Southwest
Tue, Jul 14 - Tue, Jul 28
Delta Logo
4:34 pm - 10:15 pm
MYR
-
STL
6h 41m
1 stop
Delta Logo
7:08 am - 1:00 pm
STL
-
MYR
4h 52m
1 stop
$315Delta
Thu, Aug 27 - Mon, Aug 31
Southwest Logo
1:55 pm - 3:00 pm
MYR
-
STL
2h 05mnonstop
Southwest Logo
6:05 am - 1:50 pm
STL
-
MYR
6h 45m
1 stop
$318Southwest
Sat, Aug 22 - Mon, Aug 24
Southwest Logo
11:55 am - 1:00 pm
MYR
-
STL
2h 05mnonstop
Southwest Logo
10:25 am - 1:20 pm
STL
-
MYR
1h 55mnonstop
$321Southwest
Thu, Aug 27 - Mon, Aug 31
United Airlines Logo
10:23 am - 10:00 pm
MYR
-
STL
12h 37m
2 stops
United Airlines Logo
8:00 am - 2:53 pm
STL
-
MYR
5h 53m
1 stop
$322United Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to St. Louis flights

Get data-powered insights and trends into flights from Myrtle Beach to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to St. Louis?

The average price of all round-trip flights from Myrtle Beach to St. Louis clicked on KAYAK for each day over the last 12 months.

When flying from Myrtle Beach to St. Louis, you should consider leaving on a Saturday and avoid Sundays if you are looking for the best rates. For your return to Myrtle Beach, you’ll find the best rates on Saturdays and the most expensive ones on Sundays.

What is the cheapest month to fly from Myrtle Beach to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to St. Louis is August, where tickets cost $225 (return) on average. On the other hand, the most expensive months are December and July, where the average cost of round-trip tickets is $616 and $467 respectively.

Can I save money by flying with a layover from Myrtle Beach to St. Louis?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $260, prices are generally cheapest when you fly direct.

Expert advice

Expert advice for your flight from Myrtle Beach to St. Louis

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on MYR

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Yulia Denisyuk

Yulia Denisyuk

Expert on STL

Yulia is a freelance journalist who’s dispatched from 90+ countries. Her work focuses on cultures, adventure trips and air travel, appearing in NatGeo, NYT, CNTraveler, and more. For past assignments, she’s stayed with nomads in Mongolia and learned the art of Imigongo in Rwanda. She’s based in Chicago; in winter she often questions that decision.

Good to know

Low seasonMay
Cheapest flight$136
Best time to beat the crowds but there is an average 8% increase in price.
Most popular time to fly and prices are also 14% lower on average.
Flight from Myrtle Beach to St. Louis

When to book flights from Myrtle Beach to St. Louis

Are your dates flexible? Find out the best times to travel from Myrtle Beach to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to St. Louis

  • How many flights are there between Myrtle Beach and St. Louis per day?

    Each day, there are between 1 and 2 nonstop flights that take off from Myrtle Beach and land in St. Louis, with an average flight time of 2h 06m. The most common departure time is 4:00 pm and most flights take off in the afternoon. Each week, there are 6 flights. The most frequent day of departure is Saturday, when 33% of all weekly flights depart. The fewest flights depart on a Monday.

  • What is the cheapest flight from Myrtle Beach to St. Louis?

    In the last 5 days, the lowest price for a flight from Myrtle Beach to St. Louis was $136 for a one-way ticket and $297 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and St. Louis?

    A passport is not required to fly from Myrtle Beach to St. Louis.

  • Which airports will I be using when flying from Myrtle Beach to St. Louis?

    On your way to St. Louis, you’ll fly out from Myrtle Beach Intl. You’ll be landing at Lambert-St Louis.

  • Which airlines offer Wi-Fi service onboard planes from Myrtle Beach to St. Louis?

    Delta, and American Airlines offer inflight Wi-Fi service on the Myrtle Beach to St. Louis flight route.

  • Which aircraft models fly most regularly from Myrtle Beach to St. Louis?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Myrtle Beach to St. Louis flight route.

  • Which airline alliances offer flights from Myrtle Beach to St. Louis?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and St. Louis, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Myrtle Beach to St. Louis?

    You can catch a nonstop flight from Myrtle Beach to St. Louis on on Monday, Thursday, Friday, Saturday, and Sunday.

  • Which is the best airline for flights from Myrtle Beach to St. Louis, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to St. Louis are Southwest and Delta. With an average price for the route of $361 and an overall rating of 7.9, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $350 and an overall rating of 7.8.

  • How does KAYAK find such low prices on flights from Myrtle Beach to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Myrtle Beach to St. Louis

  • Looking for a cheap flight? 25% of our users found flights on this route for $203 or less one-way and $465 or less round-trip.

Prefer to fly direct from Myrtle Beach to St. Louis?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Myrtle Beach Intl to Lambert-St Louis.
Find which airlines fly direct from Myrtle Beach Intl Airport to Lambert-St Louis Airport, which days they fly and book direct flights.

Direct departures

Myrtle Beach Intl to Lambert-St Louis

Monday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Lambert-St Louis to Myrtle Beach Intl

Monday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Reviews of the top 3 airlines serving from Myrtle Beach to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4245 reviews
8.6Crew
8.1Boarding
8.0Comfort
7.0Food
7.5Entertainment
Airline reviews

I have roller bag with food and medication told me I couldn't bring on my 2nd flight today. 15 years flying with SW never an issue with that bag.

2.0 MediocreStuart, Mar 2026
HOU - STL
Read more Southwest reviews

I have roller bag with food and medication told me I couldn't bring on my 2nd flight today. 15 years flying with SW never an issue with that bag.

I have not flown Southwest in awhile and had a very pleasant experience. From ticketing to boarding to the flight. The flight left on time and landed ahead of schedule. It won't be so long next time!!

Everything went smoothly and we even arrived a little bit early.

Boarded on time but once we were ready for take off, the crew determined that, although every seat was taken, somehow someone was on the wrong flight. Delay, delay delay, announcements and ended up with one person checking EVERY ID against their passenger Manifest only to figure out it was a "clerical error." We departed 54 minutes late causing me to run in the St. Louis Airport to make my connection and lose the priority boarding spot I had paid for. Unnecessary delay.

Southwest's seats are the least comfortable I have ever sat in.

For my birthday trip this was my second time ever flying, this trip was the best.

Crew was great flight was great baggage claim was a failure. It took over 1 hour for bags to arrive. Poor communication poor effort when I spoke to the supervisor about the delay

Everything was great except the food. The pretzels are really crappy.

I had a front row middle. I am not a big person and I barely fit in between that seat! No place to put my arms, even though the guys on each side were not taking over the arm rests. It felt like a frontier flight (if that tells you everything )

Overall is was a pretty good flight. However we were 15 mins late taking off and no one told us anything. We were all in our seats just sitting there for 15mins and all the sudden the pilot stayed we are leaving now. I think they should have at least said something after our take off time passed. Everyone was wondering what was going on. I will say the pilot did increase the speed of the plane so we arrived in time. So we weren't late.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

We departed early and made up time in the air allowing us to arrive 30 minutes early. Capt was incredibly genuine and thanked every passenger for flying with Delta. Completely humble and professional!

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

On 2 different flights the wifi was horrible and there was no drink or snack service.

There was no FREE wi-fi nor entertainment screens at all.

I just can’t understand why are you sell to many tickets ???? We had to wait 2 hours before 13 people from our flight take money and go to next day flight!

Great, on time departure, friendly and accommodating crew, great leg room, Smith flight

As we lined up to board they gave our plane to a flight going to Newark. So then we got delayed until they could find another plane. Flight crew was ok. I’m assuming since it’s a shorter flight they only offered water and coffee.

We called Kayak for a change due to the TSA situation in Atlanta. What we got was a canceled return flight (in error) and we had to find the mistake. Not happy with Kayak who blamed it on AA.

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!

Improvements in communication and empathy are absolutely necessary for American Airlines staff (top down). It’s like they are numb to the needs of their customers.

I like the speed of boarding and deplaning and the fact that everything was on time. The crew (attendants) were probably quite new and did not begin the in cabin service until 30 min before landing even though there was little to no air turbulence for the last 1.5 hours of the flight. It made for a mad scramble at the end to get trash collected and carts stowed before touch down.

The flights was delayed by hours and it was the firmest landing I have experienced in my life. My back is still sore.

I did like the employee's, they are very friendly and all smiled most of the time, Overall, from checking in bags to getting on plane, not enough employees to be able to get all on the plane, therefore I was not able to get on the plane, due to no one wea there for me to check in my bag, so I decided to go thru the security point and by the time they were done with my bags, I was told that my bag cannot be checked in, and then found out that the lady that does the check in was boarding the customers onto the plane, she said that she was going back and fourth, there for was not able to get on the plane, which changed all my flights by the time I got to Dallas, I was on standby 3 times, and wasn't sure about being able to get on the fourth plane, so ended up buying another plane ticket, so I could make my destination on time.

Not sure about entertainment as I didn't use any, so maybe there should be an NA option on this survey. Otherwise everything was just as it should be. Of course I wish planes were more comfortable and had seats that would tilt back further.

American Airlines “Randy” questioned why I needed preboarding and denied my request for same. Then Randy attempted to berate me when I boarded with my group. I was seated in an exit roll with a young man with a disability that exhibited difficulty controlling and settling himself. But Tandy questioned my disability. The flight was horrible. It was overpacked.

Everything you need to know for your flight from Myrtle Beach to St. Louis

Information on your arrival and departure airports