MYR - STL

$130 Find Cheap Flights from Myrtle Beach to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to St. Louis departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to St. Louis, as well as popular online travel agencies
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41 299 237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$264
Typical prices: $483-$381
American Airlines
Tue 5/12Fri 5/15
MYR - STL • 1 stop
Cheapest non-stop
$437
Southwest
Sat 6/27Sun 7/5
MYR - STL • Non-stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
MYR's terminals are easy to navigate with kiosks.
Use MetroLink for easy access from Lambert-St Louis.
Expert advice
Expert advice
Expert advice
Expert advice
Nonstop flights
5 days a week
Mon, Thu, Fri, Sat, Sun
You can fly direct with Southwest. Average duration is 2h 20m
Direct flights
Direct flights
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Direct flights
Direct flights
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Top airlines
Cheapest • from $264 (round-trip)
Best reviews • 8.0 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
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Top layover airports
Cheapest • Avg $328 (round-trip)
Shortest trip • 3h 53m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 36% price drop
Most popular
Good to know
Good to know
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Good to know
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Myrtle Beach to St. Louis (MYR-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to St. Louis

Tue, May 12 - Fri, May 15
American Airlines Logo
12:19 pm - 5:03 pm
MYR
-
STL
5h 44m
1 stop
American Airlines Logo
5:51 am - 12:04 pm
STL
-
MYR
5h 13m
1 stop
$264American Airlines
Tue, May 12 - Fri, May 15
American Airlines Logo
12:19 pm - 7:33 pm
MYR
-
STL
8h 14m
2 stops
American Airlines Logo
6:54 pm - 11:57 pm
STL
-
MYR
4h 03m
1 stop
$269American Airlines
Tue, May 19 - Tue, May 26
United Airlines Logo
3:14 pm - 9:13 pm
MYR
-
STL
6h 59m
1 stop
United Airlines Logo
6:00 am - 2:12 pm
STL
-
MYR
7h 12m
1 stop
$290United Airlines
Wed, Jun 24 - Tue, Jun 30
Delta Logo
11:41 am - 4:17 pm
MYR
-
STL
5h 36m
1 stop
Delta Logo
6:00 am - 10:44 am
STL
-
MYR
3h 44m
1 stop
$295Delta
Thu, Jun 4 - Tue, Jun 9
Southwest Logo
7:25 am - 12:10 pm
MYR
-
STL
5h 45m
1 stop
Southwest Logo
5:50 am - 9:10 pm
STL
-
MYR
14h 20m
2 stops
$297Southwest
Thu, Jun 4 - Tue, Jun 9
Southwest Logo
2:00 pm - 3:05 pm
MYR
-
STL
2h 05mnonstop
Southwest Logo
4:00 pm - 9:45 pm
STL
-
MYR
4h 45m
1 stop
$298Southwest
Wed, Jun 24 - Tue, Jun 30
American Airlines Logo
6:06 pm - 11:56 pm
MYR
-
STL
6h 50m
2 stops
American Airlines Logo
9:24 am - 3:32 pm
STL
-
MYR
5h 08m
1 stop
$300American Airlines
Wed, May 6 - Wed, May 13
United Airlines Logo
3:14 pm - 9:13 pm
MYR
-
STL
6h 59m
1 stop
United Airlines Logo
7:45 am - 2:18 pm
STL
-
MYR
5h 33m
1 stop
$324United Airlines
Wed, May 6 - Wed, May 13
American Airlines Logo
5:00 am - 11:47 am
MYR
-
STL
7h 47m
2 stops
American Airlines Logo
1:29 pm - 9:56 pm
STL
-
MYR
7h 27m
1 stop
$334American Airlines
Fri, May 8 - Tue, May 12
American Airlines Logo
4:09 pm - 10:19 pm
MYR
-
STL
7h 10m
2 stops
American Airlines Logo
12:27 pm - 9:56 pm
STL
-
MYR
8h 29m
2 stops
$339American Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to St. Louis flights

Get data-powered insights and trends into flights from Myrtle Beach to St. Louis to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to St. Louis?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to St. Louis departing in May.

What’s the cheapest day of the week to fly from Myrtle Beach to St. Louis?

The average price of all round-trip flights from Myrtle Beach to St. Louis clicked on KAYAK for each day over the last 12 months.

When flying from Myrtle Beach to St. Louis, you should consider leaving on a Saturday and avoid Sundays if you are looking for the best rates. For your return to Myrtle Beach, you’ll find the best rates on Sundays and the most expensive ones on Saturdays.

What is the cheapest month to fly from Myrtle Beach to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to St. Louis is August, where tickets cost $225 (return) on average. On the other hand, the most expensive months are December and May, where the average cost of round-trip tickets is $484 and $416 respectively.

Can I save money by flying with a layover from Myrtle Beach to St. Louis?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $260, prices are generally cheapest when you fly direct.

Expert advice

Expert advice for your flight from Myrtle Beach to St. Louis

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on MYR

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Yulia Denisyuk

Yulia Denisyuk

Expert on STL

Yulia is a freelance journalist who’s dispatched from 90+ countries. Her work focuses on cultures, adventure trips and air travel, appearing in NatGeo, NYT, CNTraveler, and more. For past assignments, she’s stayed with nomads in Mongolia and learned the art of Imigongo in Rwanda. She’s based in Chicago; in winter she often questions that decision.

Good to know

Low seasonOctober
Cheapest flight$130
Best time to beat the crowds with an average 21% drop in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Myrtle Beach to St. Louis

When to book flights from Myrtle Beach to St. Louis

Are your dates flexible? Find out the best times to travel from Myrtle Beach to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to St. Louis

  • What is the cheapest flight from Myrtle Beach to St. Louis?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to St. Louis was $130 for a one-way ticket and $264 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and St. Louis?

    A passport is not required to fly from Myrtle Beach to St. Louis.

  • Which airports will I be using when flying from Myrtle Beach to St. Louis?

    On your way to St. Louis, you’ll fly out from Myrtle Beach Intl. You’ll be landing at Lambert-St Louis.

  • Which airlines offer Wi-Fi service onboard planes from Myrtle Beach to St. Louis?

    American Airlines, and Delta offer inflight Wi-Fi service on the Myrtle Beach to St. Louis flight route.

  • Which aircraft models fly most regularly from Myrtle Beach to St. Louis?

    The Boeing 737-800 Passenger/BBJ2 (winglets) is the aircraft model that flies most regularly on the Myrtle Beach to St. Louis flight route.

  • Which airline alliances offer flights from Myrtle Beach to St. Louis?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and St. Louis, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Myrtle Beach to St. Louis?

    You can catch a nonstop flight from Myrtle Beach to St. Louis on on Saturday.

  • Which is the best airline for flights from Myrtle Beach to St. Louis, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to St. Louis are Southwest and Delta. With an average price for the route of $361 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $311 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Myrtle Beach to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Myrtle Beach to St. Louis

  • Looking for a cheap flight? 25% of our users found flights on this route for $366 or less round-trip.

Prefer to fly direct from Myrtle Beach to St. Louis?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Myrtle Beach Intl to Lambert-St Louis.
Find which airlines fly direct from Myrtle Beach Intl Airport to Lambert-St Louis Airport, which days they fly and book direct flights.

Direct departures

Myrtle Beach Intl to Lambert-St Louis

Monday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Lambert-St Louis to Myrtle Beach Intl

Monday

Southwest

Southwest

Thursday

Southwest

Southwest

Friday

Southwest

Southwest

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Reviews of the top 3 airlines serving from Myrtle Beach to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4334 reviews
8.1Boarding
8.0Comfort
7.0Food
8.6Crew
7.5Entertainment
Airline reviews

The crew was very kind and made going to Hawaii relaxing and fun to look forward to! Thank you Southwest for a pleasant flight!

10.0 ExcellentJasmine, Apr 2026
LGB - HNL
Read more Southwest reviews

The crew was very kind and made going to Hawaii relaxing and fun to look forward to! Thank you Southwest for a pleasant flight!

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

We waited in the airplane for over 45 min for a southwest employee to make the flight. This cause over half the plane to miss their connecting flight in Denver. When we confronted the desk upon arrival, they told us the only flight they had was the next day leaving at 8:50 pm!!! Or they offered to get us to Burbank or LA, but after that we were on our own to get back to Santa Barbara. I paid for a flight from sba to bna bna to sba. My re entry into mom mode has been 💯 rough because of southwest mistake with my flight. And now I’m leaving to Reno tomorrow for a vballl tournament and just discovered that my leg in Vegas has me and my 3 kids on a stand by flight even though I had booked these ticket last year November!! Do better southwest!

Southwest is kind of a slum airline. It’s gotten more expensive over the years for less and less service. I am a Southwest Chase Visa card holder and was forced to choose a seat in the 26th row in the middle seat. However my wife who is a rewards member but doesn’t hold a card or anything else, gets randomly assigned a normally paid seat in row 6! How does that work?

For the first time in a long time, the Wi-Fi actually worked the entire flight! The flight crew was amazing as usual.

The seat was not comfortable. 1D. My back was sore all night and the next day.

Great flight. I didn't get a drink because I was asleep whole on the flight.

Great flight from Seattle to Phoenix and to Chicago-Midway from Phoenix

The new boarding process was easy and straightforward. Very pleasant.

The flight was okay. The pilots did an amazing job and kept us updated on the flight. The flight attendants were okay. They found time to be chatty with each other rather than focus on the guests. One of the attendants was a little less warm when asking about my bag I had on my lap that I was using during latter part of the mid- flight. Mind you, it was not the departure descent. I’m respectful to each and every attendant, it was the tone in her voice reminding me to place my carryon bag on the floor. I hope to have a better experience next time.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Crew was nice, meal was good. Entertainment had to be rebooted 3 times and still did not work. Turns out there was residue on screen, it needed to be cleaned to prevent the touchscreen buttons from continuously activating. I had entertainment for the last 45 minutes of a 5 hour 45 minute flight. Really unacceptable for first class. Flight attendent indicated your cleaning solution creates this problem. Seems as if this is widely known, you should be using a different product or cleaning better. Really really disappointing which simply added to the wi fi on your planes with reliably never ever works.

The baggage belt was not updated on the Delta App and was displayed on the wrong belt board. Was not expecting this to happen.

The plan was delayed and left DC 90 minutes late. However, it showed a 20 minute delay on the delta app, then a 12 min delay. It turned out to be an hour delay. I found out where the plane was with flightaware. Stop keeping customers in the dark about what is going on.

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

Landed without a gate ready. Plane is extremely old and dirty.

All the amenities was wonderful, if they could keep their prices that low. I'd fly with them all the time.

Very old plane with no inflight entertainment. I purchased the internet pass and it was nearly unusable.

My tray was broken so i had no place to work or eat except my lap. Flight attendant said I would get an email with some credit or miles, it was a complete waste of time as I could only function at about 20% of normal. I have not received anything yet.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

On time departure and early arrival. Flight attendant very nice.

As we approached Denver, we encountered quite a bit of turbulence. I know this can sometimes be the case as I frequently fly this route but not on American. My gripe: Usually a pilot or co-pilot alerts passengers to the possibility of turbulance ahead of time. This did not occur nor did he communiucate during what was a pretty rough ride.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

Overall a good experience, however Wifi was not working on the flight.

Airlines should be prohibited from using the seats they get away with.

My flight got delayed a total of five times. And the boarding gate changed four times. most of the time the platform was not up-to-date with the changes taking place. The most discouraging part of the entire trip by far.

Flight left early and arrived 30 MINUTES early at the destination. Smooth trip.

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Everything you need to know for your flight from Myrtle Beach to St. Louis

Information on your arrival and departure airports