MYR - STL

$105 Find Cheap Flights from Myrtle Beach to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to St. Louis departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to St. Louis, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Myrtle Beach to St. Louis (MYR-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to St. Louis

Wed, Oct 22 - Sun, Oct 26
Spirit Airlines Logo
8:06 pm - 10:02 amMYR-STL
14h 56m1 stop
Spirit Airlines Logo
10:57 am - 8:04 pmSTL-MYR
8h 07m1 stop
$273Spirit Airlines
Find Deal
Sun, Oct 5 - Sun, Oct 12
 Logo
7:39 pm - 8:37 pmMYR-STL
25h 58m1 stop
 Logo
6:05 pm - 5:44 pmSTL-MYR
22h 39m1 stop
Tue, Sep 30 - Wed, Oct 1
Delta Logo
10:55 am - 2:35 pmMYR-STL
4h 40m1 stop
Delta Logo
5:11 pm - 11:49 pmSTL-MYR
5h 38m1 stop
$297Delta
Find Deal
Thu, Oct 16 - Tue, Oct 21
Delta Logo
6:58 pm - 11:41 pmMYR-STL
5h 43m1 stop
Delta Logo
1:30 pm - 6:03 pmSTL-MYR
3h 33m1 stop
$307Delta
Find Deal
Thu, Oct 16 - Tue, Oct 21
American Airlines Logo
5:21 am - 8:16 amMYR-STL
3h 55m1 stop
American Airlines Logo
10:54 am - 6:45 pmSTL-MYR
6h 51m2 stops
$312American Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 17
Southwest Logo
11:10 am - 2:15 pmMYR-STL
4h 05m1 stop
Southwest Logo
8:10 am - 7:45 pmSTL-MYR
10h 35m2 stops
$322Southwest
Find Deal
Thu, Nov 13 - Mon, Nov 17
Southwest Logo
8:00 am - 3:10 pmMYR-STL
8h 10m2 stops
Southwest Logo
10:15 am - 7:45 pmSTL-MYR
8h 30m2 stops
$327Southwest
Find Deal
Fri, Sep 19 - Mon, Sep 22
American Airlines Logo
5:52 pm - 10:50 pmMYR-STL
5h 58m1 stop
American Airlines Logo
1:21 pm - 9:09 pmSTL-MYR
6h 48m2 stops
$349American Airlines
Find Deal
Tue, Sep 30 - Thu, Oct 2
United Airlines Logo
4:33 pm - 10:35 pmMYR-STL
7h 02m1 stop
United Airlines Logo
6:30 am - 4:56 pmSTL-MYR
9h 26m2 stops
$414United Airlines
Find Deal
Fri, Sep 12 - Mon, Sep 15
United Airlines Logo
4:45 pm - 9:32 pmMYR-STL
5h 47m1 stop
United Airlines Logo
6:35 am - 2:42 pmSTL-MYR
7h 07m1 stop
$437United Airlines
Find Deal
Expert advice

Expert advice for your flight from Myrtle Beach to St. Louis

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airports
MYR

MYR's terminals are easy to navigate with kiosks supplementing traditional check-in counters, but expect longer lines with low-cost airlines.

Read more about MYRby Ramsey Qubein
STL

Use MetroLink for easy access to St. Louis. The Red Line connects the airport to downtown and other key areas.

Read more about STLby Yulia Denisyuk
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on MYR

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Yulia Denisyuk

Yulia Denisyuk

Expert on STL

Yulia Denisyuk

Yulia Denisyuk

Yulia is a freelance journalist who’s dispatched from 90+ countries. Her work focuses on cultures, adventure trips and air travel, appearing in NatGeo, NYT, CNTraveler, and more. For past assignments, she’s stayed with nomads in Mongolia and learned the art of Imigongo in Rwanda. She’s based in Chicago; in winter she often questions that decision.

Read more
Booking Insights

KAYAK's insights & trends for Myrtle Beach to St. Louis flights

Get data-powered insights and trends into flights from Myrtle Beach to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to St. Louis?

The average price of all round-trip flights from Myrtle Beach to St. Louis clicked on KAYAK for each day over the last 12 months.

When flying from Myrtle Beach to St. Louis, you should consider leaving on a Tuesday and avoid Sundays if you are looking for the best rates. For your return to Myrtle Beach, you’ll find the best rates on Tuesdays and the most expensive ones on Sundays.

What is the cheapest month to fly from Myrtle Beach to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to St. Louis is August, where tickets cost $271 (return) on average. On the other hand, the most expensive months are December and February, where the average cost of round-trip tickets is $423 and $421 respectively.

Can I save money by flying with a layover from Myrtle Beach to St. Louis?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $260, prices are generally cheapest when you fly direct.

Good to know

Low seasonFebruary
Cheapest flight$105
Best time to beat the crowds but there is an average 11% increase in price.
Most popular time to fly with an average 1% increase in price.
Flight from Myrtle Beach to St. Louis

When to book flights from Myrtle Beach to St. Louis

Are your dates flexible? Find out the best times to travel from Myrtle Beach to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to St. Louis

  • What is the cheapest flight from Myrtle Beach to St. Louis?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to St. Louis was $105 for a one-way ticket and $273 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and St. Louis?

    A passport is not required to fly from Myrtle Beach to St. Louis.

  • Which airports will I be using when flying from Myrtle Beach to St. Louis?

    On your way to St. Louis, you’ll fly out from Myrtle Beach Intl. You’ll be landing at Lambert-St Louis.

  • Which airlines offer Wi-Fi service onboard planes from Myrtle Beach to St. Louis?

    American Airlines, and Delta offer inflight Wi-Fi service on the Myrtle Beach to St. Louis flight route.

  • Which aircraft models fly most regularly from Myrtle Beach to St. Louis?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Myrtle Beach to St. Louis flight route.

  • On which days can I fly direct from Myrtle Beach to St. Louis?

    You can catch a nonstop flight from Myrtle Beach to St. Louis on on Saturday, and Sunday.

  • Which is the best airline for flights from Myrtle Beach to St. Louis, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to St. Louis are Southwest and Delta. With an average price for the route of $382 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $381 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Myrtle Beach to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Myrtle Beach to St. Louis

  • Looking for a cheap flight? 25% of our users found flights on this route for $178 or less one-way.

Prefer to fly direct from Myrtle Beach to St. Louis?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Myrtle Beach Intl to Lambert-St Louis.
Find which airlines fly direct from Myrtle Beach Intl Airport to Lambert-St Louis Airport, which days they fly and book direct flights.

Direct departures

Myrtle Beach Intl to Lambert-St Louis

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Direct returns

Lambert-St Louis to Myrtle Beach Intl

Saturday

Southwest

Southwest

Sunday

Southwest

Southwest

See more direct flights

Reviews of the top 3 airlines serving from Myrtle Beach to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4241 reviews
8.1Boarding
8.0Comfort
8.6Crew
7.0Food
7.5Entertainment
Airline reviews

AC sub par. WiFi not working correctly. Ac sucked. Seats very narrow.

2.0 MediocreMike, Aug 2025AUS - BWI
Read more Southwest reviews

AC sub par. WiFi not working correctly. Ac sucked. Seats very narrow.

Near 4 hour flight with only 1 service. Had to use call button to request water. Internet and power not working until into flight. Internet would stop working during flight.

Southwest's seats are the least comfortable I have ever sat in.

The cabin was quiet for the redeye flight. The area was clean. The staff was great. The 787 Max was in good condition. Drawbacks were that the seat widths were tight for some passengers. The seat padding was at best average and for a long flight uncomfortable.

Southwest like most American domestic airlines, is a mediocre airline. But it is among the cheapest. Oh well.

My flight was delayed 50 minutes and we were rushed to board to then sit for 15 minutes until the pilot arrived. Unacceptable since we could have waited to board. Also the delayed flight was updated AFTER we boarded to more than the 10 minutes as originally stated.

Other than a bit of a delay, everything was good. Again, the boarding process and picking seats is the only thing I don't enjoy.

If we are going to have to pay for luggage, make it easier to do. Put something on the app during check-in so I don't need to do it at the kiosk. I've done it twice recently and I ended up having to pay at the desk because something went wrong at the kiosk in Tampa.

southwest just starting charging for luggage. hadnt realized it until it was too late. now out $70 when i couldve bought a carry on if i wouldve known. free bags was one of the only reasons i chose southwest over another airline (the other being no assigned seats, which is apparently also being changed). stupid business decision. wont be flying southwest anymore.

The quality of Southwest Airlines continues to degrade each time I fly with them. If it were not for the free luggage, I would probably choose another airline. Their prices are a little bit competitive, but way too high for the quality of the service. Southwest is not unique in this way. Domestic flight in the United States of America has continued to be a lower and lower quality product. Very sad when you compare the quality of domestic airlines to that of many international airlines around the world.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Delayed due to thunderstorms and no in-flight service due to rough weather — both of which are out of Delta’s control. Flight was good overall.

The flight attendants in SLC were rude. I arrived 40 minutes early to gate. Ticket said I needed check in for seat assignments and tried check in and attendants said they weren’t doing it. And proceeded to never call me to give me a ticket so when time to board I received the very last seat. Please relay to employees to do their job better..,

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

The seats got pretty uncomfortable pretty fast. The armrests are bigger than on other planes, so I had less room in the actual seat. My butt hurt by the end of the flight. :/ comfort was the primary issue. The crew were fantastic!

I believe that a four-hour trip should have a meal. Delta had none.

Great flight with Delta! Boarding was quick and easy, the amenities were solid, and the plane was in great shape. The flight attendants had a fun, lively energy while staying professional. All in all, a smooth trip — even managed to catch up on some rest. Thanks, Delta!

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

The AA staff person who checked our bags was curt and almost rude. The FA also seemed unhappy doing her job. Overall it was like riding the school bus back in grade school.

Internet was a bit expensive and did not work ask that week otherwise a good flight

Ring in first class for an overnight flight, there was no blankets nor pillows for first class customers.

My Internet did not work for Outlook email or basically anything. I paid for one hour of in-flight usage and it was terrible. I spent a lot of time on different sites and browsers with no luck and a lot of frustration. Other than that, the flight was on time, crew was nice, service was fine. Seat was OK even though I paid for the extra 6 inches. I cannot imagine how tight the seats in the back must be.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

Any flight to ORD after about 2pm this summer has been challenging. Flight was delayed getting in (coming from ORD) and that led to it not leaving before a ground stop due to lightening before they could fuel the plane, and so forth. They made up some time but we were still late in arriving at ORD, and that led to missed connections.

Food was ok, but not as good as I have had before on AA.

No issues. They did change our gate FOUR times in about 30 minutes which was mildly annoying but the flight was fine.

Great flight. No issues at all. I still think boarding could be more efficient but otherwise, a good experience.

Everything you need to know for your flight from Myrtle Beach to St. Louis

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