MYR - STL

$124 Find Cheap Flights from Myrtle Beach to St. Louis

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to St. Louis departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to St. Louis, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$205
Overall average: $381
American Airlines
Thu 3/5Mon 3/9
MYR - STL • 1 stop
Cheapest one-way
$103
Typical prices: $166-$262
American Airlines
Tue 3/17
MYR - STL • 1 stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
MYR's terminals are easy to navigate with kiosks.
Use MetroLink for easy access from Lambert-St Louis.
Expert advice
Expert advice
Expert advice
Expert advice
Nonstop flights
1 day a week
Sat
You can fly direct with Southwest. Average duration is 2h 30m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top airlines
United Airlines
Cheapest • from $252 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Atlanta (ATL)
Cheapest • Avg $361 (round-trip)
Baltimore (BWI)
Shortest trip • 4h 20m (one-way)
Insights
Insights
Insights
Insights
When to travel
August
Cheapest • 15% price drop
March
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Myrtle Beach to St. Louis (MYR-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to St. Louis

Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
5:10 am - 8:35 am
MYR
-
STL
4h 25m
1 stop
American Airlines Logo
6:57 pm - 11:55 pm
STL
-
MYR
3h 58m
1 stop
$205American Airlines
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
5:10 am - 8:35 am
MYR
-
STL
4h 25m
1 stop
American Airlines Logo
3:49 pm - 11:55 pm
STL
-
MYR
7h 06m
2 stops
$210American Airlines
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
5:10 am - 12:33 pm
MYR
-
STL
8h 23m
2 stops
American Airlines Logo
3:49 pm - 11:55 pm
STL
-
MYR
7h 06m
2 stops
$215American Airlines
Fri, May 1 - Tue, May 5
United Airlines Logo
3:14 pm - 9:08 pm
MYR
-
STL
6h 54m
1 stop
United Airlines Logo
7:45 am - 2:18 pm
STL
-
MYR
5h 33m
1 stop
$252United Airlines
Fri, Apr 17 - Mon, Apr 20
American Airlines Logo
5:00 am - 8:30 am
MYR
-
STL
4h 30m
1 stop
American Airlines Logo
6:29 am - 12:16 pm
STL
-
MYR
4h 47m
1 stop
$257American Airlines
Fri, Mar 6 - Tue, Mar 10
American Airlines Logo
3:17 pm - 7:30 pm
MYR
-
STL
5h 13m
1 stop
American Airlines Logo
9:21 am - 6:37 pm
STL
-
MYR
8h 16m
2 stops
$262American Airlines
Wed, Jun 24 - Tue, Jun 30
United Airlines Logo
6:50 pm - 11:35 pm
MYR
-
STL
5h 45m
1 stop
United Airlines Logo
7:30 am - 2:34 pm
STL
-
MYR
6h 04m
1 stop
$267United Airlines
Fri, Apr 17 - Mon, Apr 20
American Airlines Logo
4:52 pm - 10:59 pm
MYR
-
STL
7h 07m
1 stop
American Airlines Logo
2:33 pm - 11:57 pm
STL
-
MYR
8h 24m
2 stops
$289American Airlines
Fri, Apr 17 - Mon, Apr 20
American Airlines Logo
5:00 am - 8:30 am
MYR
-
STL
4h 30m
1 stop
American Airlines Logo
2:33 pm - 11:57 pm
STL
-
MYR
8h 24m
2 stops
$291American Airlines
Fri, Mar 6 - Tue, Mar 10
American Airlines Logo
3:17 pm - 11:35 pm
MYR
-
STL
9h 18m
2 stops
American Airlines Logo
9:21 am - 6:37 pm
STL
-
MYR
8h 16m
2 stops
$294American Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to St. Louis flights

Get data-powered insights and trends into flights from Myrtle Beach to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to St. Louis?

The average price of all round-trip flights from Myrtle Beach to St. Louis clicked on KAYAK for each day over the last 12 months.

When flying from Myrtle Beach to St. Louis, you should consider leaving on a Sunday and avoid Saturdays if you are looking for the best rates. For your return to Myrtle Beach, you’ll find the best rates on Saturdays and the most expensive ones on Sundays.

What is the cheapest month to fly from Myrtle Beach to St. Louis?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to St. Louis, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to St. Louis is August, where tickets cost $316 (return) on average. On the other hand, the most expensive months are December and April, where the average cost of round-trip tickets is $484 and $417 respectively.

Can I save money by flying with a layover from Myrtle Beach to St. Louis?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $260, prices are generally cheapest when you fly direct.

Expert advice

Expert advice for your flight from Myrtle Beach to St. Louis

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on MYR

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Yulia Denisyuk

Yulia Denisyuk

Expert on STL

Yulia is a freelance journalist who’s dispatched from 90+ countries. Her work focuses on cultures, adventure trips and air travel, appearing in NatGeo, NYT, CNTraveler, and more. For past assignments, she’s stayed with nomads in Mongolia and learned the art of Imigongo in Rwanda. She’s based in Chicago; in winter she often questions that decision.

Good to know

Low seasonDecember
Cheapest flight$103
Best time to beat the crowds but there is an average 30% increase in price.
Most popular time to fly with an average 2% increase in price.
Flight from Myrtle Beach to St. Louis

When to book flights from Myrtle Beach to St. Louis

Are your dates flexible? Find out the best times to travel from Myrtle Beach to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to St. Louis

  • How many flights are there between Myrtle Beach and St. Louis per day?

    There is a maximum of 1 nonstop flight a day that takes off from Myrtle Beach and lands in St. Louis, with an average flight time of 2h 30m. The most common departure time is 3:00 pm and most flights take off in the afternoon. Each week, there are 1 flights.

  • What is the cheapest flight from Myrtle Beach to St. Louis?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to St. Louis was $124 for a one-way ticket and $252 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and St. Louis?

    A passport is not required to fly from Myrtle Beach to St. Louis.

  • Which airports will I be using when flying from Myrtle Beach to St. Louis?

    On your way to St. Louis, you’ll fly out from Myrtle Beach Intl. You’ll be landing at Lambert-St Louis.

  • Which airlines offer Wi-Fi service onboard planes from Myrtle Beach to St. Louis?

    American Airlines, and Delta offer inflight Wi-Fi service on the Myrtle Beach to St. Louis flight route.

  • Which aircraft models fly most regularly from Myrtle Beach to St. Louis?

    The Boeing 737 MAX 8 is the aircraft model that flies most regularly on the Myrtle Beach to St. Louis flight route.

  • Which airline alliances offer flights from Myrtle Beach to St. Louis?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and St. Louis, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Myrtle Beach to St. Louis?

    You can catch a nonstop flight from Myrtle Beach to St. Louis on on Saturday.

  • Which is the best airline for flights from Myrtle Beach to St. Louis, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to St. Louis are Southwest and Delta. With an average price for the route of $381 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $351 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Myrtle Beach to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Myrtle Beach to St. Louis?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Myrtle Beach Intl to Lambert-St Louis.
Find which airlines fly direct from Myrtle Beach Intl Airport to Lambert-St Louis Airport, which days they fly and book direct flights.

Direct departures

Myrtle Beach Intl to Lambert-St Louis

Saturday

Southwest

Southwest

See more direct flights

Direct returns

Lambert-St Louis to Myrtle Beach Intl

Saturday

Southwest

Southwest

See more direct flights

Reviews of the top 3 airlines serving from Myrtle Beach to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4300 reviews
7.5Entertainment
8.6Crew
8.1Boarding
7.0Food
8.0Comfort
Airline reviews

I have not flown Southwest in awhile and had a very pleasant experience. From ticketing to boarding to the flight. The flight left on time and landed ahead of schedule. It won't be so long next time!!

10.0 ExcellentTy&Steph, Feb 2026
CLT - STL
Read more Southwest reviews

I have not flown Southwest in awhile and had a very pleasant experience. From ticketing to boarding to the flight. The flight left on time and landed ahead of schedule. It won't be so long next time!!

The Southwest experience has definitely taken a dive from its early days. You can no longer deferentiate from other airlines. Air travel is too expensive. Southwest is no longer budget friendly. They have lost me as a loyal customer.

Flight was hours late, unable to sit next to spouse, I have had so much better experiences. Substantially better, only saving grace was that it was a short flight.

An entire day of delays. Cost lots of money. Meals and a hotel.

Great plane, great attendants,great flight crew,on time. Wonderful flight home..

The WiFi and crew on the plane were good, however, the boarding experience was awful. I paid for the Choice Preferred and was boarded in group 5 so all overhead storage was full. They found room for our luggage, but further back making getting off the plane a nightmare. Also, we were in row 6 and the seats were extremely uncomfortable. Both my daughter and I had no leg room and couldn’t wait to get off the plane.

The charges were ridiculous for an hour flight and the turbulence was very scary.

Still need to work out the kinks on the new assigned seating boarding process. Otherwise, a very good flight.

WiFi did not work. Boarding with the new seating assignments took too long. The temperature in the terminal was obnoxious. +/- 80°

The seats are now more narrow. I paid for front row the seats in the front are even more narrow than before.

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

Flight was delayed due to crew being not on time

Flight crew issues delayed my flight by 2 1/2 hours. Causing me to miss my connection.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

The staff was frielndly. The plane was terrible, it was too small and should be decommissioned. There were no back seat screens at all. The only beverages we had a choice from was coffee, tea or water. The only bathroom in the back was behind the flight attendant's jump seat and wasn't working. And I literally felt like I was sitting on top of the guy next to me. It was terribly hot in the plane and we had to sit on the tarmac in Chicago for 1/2 hour due to congestion in Mpls. Wouldn't they have know that before they even boarded us so that we could have sat in comfort in the terminal?

Never got on it. Was re-routed through Detroit and am still in airports 12 hours later waiting for my connecting plane to arrive.

Delta has too many delays now days. It is 1:06 am now. I was supposed to land in Norfolk at 10:30 pm. I got re-booked through Detroit and I’m still in Detroit. I hope to be landed in Norfolk by 3am. I’ve been in airports for 12 hours as of right now. There is a weather delay now but most delays lately have been maintenance.

Very Very late. Subsequent flights left an hour before ours

This is my worse experience with Delta. My colleagues and I were traveling to ICT for work. Usually we connect in Dallas, but this year we decided to book with Delta and connect in Atlanta. We were excited to fly with Delta because we hear great things and Delta is one of my top choices when choosing an airline for travel. On the connecting flights to and from Wichita/Atlanta - it felt hot and uncomfortable on the plane. The plane to ICT was smaller and older and did not have any wi-fi or entertainment. The most terrible experience was at boarding in Atlanta both times traveling to Wichita and then back to Tampa. First on our flight from ATL to ICT - the attendant scanning our boarding pass made us go back to the line when we went up to scan our passes to wait. After a few minutes, she allowed us to come back up to scan but then she asked what boarding zone we were. We told her zone 5, and since we were standing on the wrong side of the small rope partition, she made us go back to stand on the right side. There was another gentleman that came up to board and scan his pass, and she mentioned he was also on the wrong side but she let him go through. Our group had to walk back and forth for no reason, causing an unnecessary delay to board the plane. We have never experienced anything like this, especially when the boarding area was completely empty and everyone already boarded since boarding was earlier than the original boarding time. On our flight from ATL to TPA, the attendants scanning our boarding passes had us scan our passes twice, not explaining to us what was going on. They automatically started tagging our carry on bags and did not explain to us or tell us what was going on and why this was happening. Obviously we knew our bags were being forced to check in but with no reason. There was no announcement or mention and I have never had anyone force me to check in my bag before boarding the plane. We assumed the overhead bins were full but when we boarded the plane, there was a lot of empty bins and a lot of spaces to put our bags. We all were disappointed and frustrated with Delta and will be hesitant to fly Delta again or anytime soon.

Boarding and crew were fantastic, but I paid for a window seat with no window. Seat 11D on a CRJ-900 apparently does not have a window. Lesson learned.

Never ontime and always delays. Long waits for customer service and often app doesn’t work

Arriving plane went to wrong gate. Flight Attendant was late. Was in no Hurry when he arrived. Flight was fine. Plane had to wait 20 minutes to get assigned a gate due to designated gate tied up. barely connected.. Boarded extremely late on final leg of trip.

We arrived 25 minutes early only to be told our gate was occupied and so we sat for close to 30 minutes to pull into a gate. That’s not an early arrival!

Experience was great. The best part is the free Wi-Fi connection which helps me to work on the flight

The gate agent had a really bad attitude and refused to help me get on the standby list. She just handed me a card and said I needed to call a number. I asked her to help with the AA app on my phone and she just shrugged and said she didnt know. After a few phone calls, I eventually just went to a different gate agent on the other side of the terminal and got the help I needed.

The TSA check in took 1.5 hours to get through in Austin and I missed my flights back to DC

As previously stated the delay I experienced flying from Wichita to Chicago caused a host of issues. When I finally was able to be booked on the last remaining American flight from Chicago to Cincinnati, the gate changed four times with the last change occurring very near the scheduled boarding time. While I didn't have a problem moving from gate to gate, I did notice and make note of others that had mobility issues and had to move each time for the gate change.

Overall, my last three trips on American Airlines have all been either delayed or "rescheduled" due to mechanical issues. At least on delay caused me to miss two possible connecting flights each later than the first. My last option for my last connection required the assistance of the onsite service desk (O'Hare Airport). The wait time for the service desk was such that it jeopardized getting booked on the last connecting flight available for the night. Suffice it to say, my latest experiences with American Airlines have caused me extensive loss of productive business and personal time and can therefore be classified as significantly less than satisfactory.

There was free WiFi (definitely a plus), but the flight was delayed 45 minutes waiting on a catering truck that never arrived. The pilot said there would be food vouchers given out at the end of the gangway to make up for the inconvenience, but there was no one offering those. Delay made me late for work!

Waiting for gate in RDU for more than 20mins is crazy.

Everything you need to know for your flight from Myrtle Beach to St. Louis

Information on your arrival and departure airports