$153 Find Cheap Flights from Myrtle Beach to St. Louis - Compare and Save

Two cabin classes are available on flights from Myrtle Beach to St. Louis:

• Economy Class
• First Class

A nonstop flight from Myrtle Beach to St. Louis takes 00m, covering 727 miles.

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Round-trip flights from Myrtle Beach to St. Louis range from $350 to $420, with an average of $368 over the past 12 months. Anything below $350 counts as a good deal.

On this route, layover flights are cheaper than nonstop options on average. Layover fares average $340 round-trip via Washington, D.C. Reagan-National (DCA), compared to $391 for nonstop.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $45–$45 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Airbus A320-100/200 family is used most often on this route, operated mainly by Delta. Other aircraft seen on the route include Boeing 737 MAX 8 variants.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $311 to $1,115. That means the highest observed fare was about 4x higher than the lowest one.

One-way fares from Myrtle Beach to St. Louis are currently lower than usual. Average one-way flight prices are about $197, which is 11% below the typical average for this route.

Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates starting from around $31 for economy cars. Top options include:

• Hertz
• Budget
• Alamo
• Enterprise Rent-A-Car
• Payless

Flights from Myrtle Beach to St. Louis usually depart from Myrtle Beach Intl (MYR) and arrive at Lambert-St Louis (STL).

One-stop flights from Myrtle Beach to St. Louis most commonly connect through:

• Charlotte Douglas (CLT) - 67% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) - 23% of one-stop connections
• Nashville Intl (BNA) - 8% of one-stop connections
• Washington, D.C. Reagan-National (DCA) - 3% of one-stop connections

Yes. Flexible dates can save you up to 26% on flights from Myrtle Beach to St. Louis. Monday is the cheapest departure day at $335 round-trip on average, while Sunday is the most expensive at $447, a difference of $112.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Flying via Charlotte Douglas (CLT) gives the shortest average 1-stop total travel time at 4h 12m, compared with 4h 16m via Atlanta Hartsfield-Jackson (ATL) and 4h 19m via Nashville Intl (BNA).

St. Louis is 1 hour behind Myrtle Beach (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

Some of the most popular sights in St. Louis are Busch Stadium, Enterprise Center and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

Here are some options for this route, based on selected ticket types and cabin classes:

• Southwest: a cabin bag in Economy Class class

Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.