MYR - SDF

$116 Find Cheap Flights from Myrtle Beach to Louisville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Louisville departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Louisville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Louisville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Louisville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$196
Overall average: $325
Spirit Airlines
Thu 4/16Mon 4/20
MYR - SDF • 1 stop
Cheapest one-way
$116
Typical prices: $89-$136
Multiple Airlines
Sun 5/10
MYR - SDF • 1 stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
Allegiant's Bonus bundle includes carry-on and flexibility.
Spirit's Wi-Fi offers gate-to-gate connectivity.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Spirit Airlines
Cheapest • from $196 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Chicago (ORD)
Cheapest • Avg $290 (round-trip)
Atlanta (ATL)
Shortest trip • 3h 58m (one-way)
Insights
Insights
Insights
Insights
When to travel
May
Cheapest • 77% price drop
September
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Myrtle Beach to Louisville (MYR-SDF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Louisville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Louisville

Thu, Apr 16 - Mon, Apr 20
Spirit Airlines Logo
11:52 am - 5:04 pm
MYR
-
SDF
5h 12m
1 stop
Spirit Airlines Logo
6:06 pm - 11:29 pm
SDF
-
MYR
5h 23m
1 stop
$196Spirit Airlines
Thu, May 28 - Sun, May 31
Spirit Airlines Logo
11:52 am - 5:04 pm
MYR
-
SDF
5h 12m
1 stop
Spirit Airlines Logo
6:06 pm - 11:29 pm
SDF
-
MYR
5h 23m
1 stop
$216Spirit Airlines
Tue, Mar 31 - Wed, Apr 1
American Airlines Logo
6:01 am - 9:51 am
MYR
-
SDF
3h 50m
1 stop
American Airlines Logo
6:00 am - 9:57 am
SDF
-
MYR
3h 57m
1 stop
$255American Airlines
Tue, Mar 31 - Wed, Apr 1
American Airlines Logo
5:40 pm - 9:11 pm
MYR
-
SDF
3h 31m
1 stop
American Airlines Logo
6:33 am - 2:27 pm
SDF
-
MYR
7h 54m
2 stops
$260American Airlines
Thu, Apr 16 - Tue, Apr 21
United Airlines Logo
5:55 pm - 11:12 pm
MYR
-
SDF
5h 17m
1 stop
United Airlines Logo
9:07 am - 2:17 pm
SDF
-
MYR
5h 10m
1 stop
$268United Airlines
Thu, Apr 16 - Tue, Apr 21
Delta Logo
7:02 pm - 11:59 pm
MYR
-
SDF
4h 57m
1 stop
Delta Logo
6:00 am - 9:40 am
SDF
-
MYR
3h 40m
1 stop
$273Delta
Sat, Apr 25 - Wed, Apr 29
American Airlines Logo
5:00 am - 12:45 pm
MYR
-
SDF
7h 45m
2 stops
American Airlines Logo
6:00 am - 11:35 am
SDF
-
MYR
5h 35m
1 stop
$280American Airlines
Thu, Mar 19 - Mon, Mar 23
Multiple Airlines Logo
10:27 am - 11:14 am
MYR
-
SDF
24h 47m
1 stop
Multiple Airlines Logo
9:13 pm - 5:33 pm
SDF
-
MYR
20h 20m
1 stop
$287Multiple Airlines
Sat, Mar 21 - Sat, Mar 28
American Airlines Logo
5:10 am - 8:50 am
MYR
-
SDF
3h 40m
1 stop
American Airlines Logo
5:00 am - 8:20 am
SDF
-
MYR
3h 20m
1 stop
$291American Airlines
Thu, Apr 16 - Tue, Apr 21
Delta Logo
7:02 pm - 11:59 pm
MYR
-
SDF
4h 57m
1 stop
Delta Logo
7:56 am - 11:55 am
SDF
-
MYR
3h 59m
1 stop
$293Delta
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Louisville flights

Get data-powered insights and trends into flights from Myrtle Beach to Louisville to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Louisville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Louisville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Louisville is May, where tickets cost $73 (return) on average. On the other hand, the most expensive months are March and December, where the average cost of round-trip tickets is $555 and $410 respectively.

Can I save money by flying with a layover from Myrtle Beach to Louisville?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $368, prices are generally cheapest when you fly direct.

Expert advice

Expert advice for your flight from Myrtle Beach to Louisville

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Joe Cortez

Joe Cortez

Expert on Spirit Airlines

Joe Cortez is a seasoned managing editor in aviation with over a decade of industry experience. His work has been featured on prominent platforms such as FlyerTalk and TripSavvy, establishing him as a respected voice in aviation journalism.

Daniel Scheffler

Daniel Scheffler

Expert on Allegiant Air

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Good to know

Low seasonJanuary
Cheapest flight$116
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly with an average 4% increase in price.
Flight from Myrtle Beach to Louisville

When to book flights from Myrtle Beach to Louisville

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Louisville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Louisville

  • What is the cheapest flight from Myrtle Beach to Louisville?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Louisville was $116 for a one-way ticket and $196 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Louisville?

    A passport is not required to fly from Myrtle Beach to Louisville.

  • Which airports will I be using when flying from Myrtle Beach to Louisville?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in Louisville is Louisville Intl.

  • Which aircraft models fly most regularly from Myrtle Beach to Louisville?

    The Airbus A320neo is the aircraft model that flies most regularly on the Myrtle Beach to Louisville flight route.

  • Which airline alliances offer flights from Myrtle Beach to Louisville?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and Louisville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to Louisville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Louisville are Delta and American Airlines. With an average price for the route of $321 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $370 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Louisville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Louisville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Louisville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Louisville from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Louisville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Louisville with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SDF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Louisville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Louisville from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Louisville

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Louisville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Louisville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8248 reviews
7.8Entertainment
7.2Food
7.9Comfort
8.5Crew
8.1Boarding
Airline reviews

The whole experience was excellent. As it most often is with Delta

10.0 ExcellentRay, Mar 2026
LGA - MCO
Read more Delta reviews

The whole experience was excellent. As it most often is with Delta

Cabin was not pressurized properly. Several passengers had respiratory difficulties.

I was happy that I was able to get a last minute flight but unfortunately my seat was a middle seat. Even with Delta Comfort I wasn't comfortable

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Flight was warm for first few hours and quite rough

Seat was extremely hard which made even a short 1 hour 20 minute flight fairly uncomfortable.

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

Flight pulled out on time but sat on runway for 30 mins. It was extremely cold in the aircraft despite wearing a winter coat. Surprisingly they had a vegetarian meal but could have some better snack choices for a 8 hour flight.

We had a male flight attendant who was super attentive and wonderful! Very professional. I have both gluten and dairy intolerance, and was only able to get a gluten free part, and not the dairy free part of the meal. Easy to order ahead of time and I appreciate being able to do that.

Snow delayed boarding several times, which I understand happens. Issue I had was that after we did board, pilot told us we were going to roll out to be de-iced, then on our way. We were de-iced once, taxied to the tarmac and then stopped. Sat for another 30 minutes or so, the another de-icing. Then we rolled out to a parking spot, only to sit for another hour due to a traffic stop in DCA, which I'm confident they knew would happen before we boarded. Pilot gave no updates other than we had to hold, attendants did speak to the crew, but when asked, said the pilot would be updating us. We on the ground in the plane waiting for over 2 hours. They did communicate that bathrooms would be open, but no other news until we left. Would have been better to be up front about status.

Good crew and flight was on time. It’s a small plane with limited overhead luggage space. They said the overhead space was full and I had to check my bag. There was still space when I got on. Waiting for my checked luggage added 30 minutes to my trip. Not the end of the world but also not great.

My seat was assigned last row behind restrooms No legroom’s I’m very Pettit Still was not comfortable Food choice was excellent

Delayed initially because they couldn’t print the flight details. Poor instruction on delay. When I got on the plane the flight attendant argued with me about whether my carry on would fit (it did, although she didn’t acknowledge that). No greeting (other than arguing with me) getting on or off the plane.

Overall good. The pilots and flight attendants are excellent! The equipment was the issue on my First flight as they had to wait for a part to be installed. So the take off was at least 30 minutes later.

It was an older plane. First Class was not especially roomy or comfortable. It was a short flight so there were no meal but they did offer mixed nuts which used to be normal but now is rare. Crew member was very polite and professional.

The chicken wrap was tiny ($13 for what looked like a 1/3 of a normal wrap?) and disgusting.

It was a train wreck but on an airplane. First off, flight was delayed then we board only to hear two announcements, First weather delays in Orlando and second backup battery warning on emergency lights. After sitting on the plane for almost 2 hours they have us deplane due to the maintenance issue. We were told they were getting another plane. In the mean time, I notice another American- Orlando flight and ask the gate agent if I can switch. He says he cant help me and I'd have to walk to A13 from A37. Really!? I get down there and get a seat only to get an announcement my original flight was RE-boarding. The Then inflight there's no communication and I notice on flightaware were circling over the Gulf of America. I call the flight attendant and of course she has no clue and apparently 5m later the pilot finally tells us about another delay. Why does American always have these service and delay issues? They are my LAST choice in flights now!

Everything you need to know for your flight from Myrtle Beach to Louisville

Information on your arrival and departure airports