MYR - SDF

$220 Find Cheap Flights from Myrtle Beach to Louisville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Louisville departing on 1/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Louisville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Louisville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Louisville, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$300
Overall average: $291
United Airlines
Wed 1/14Sun 1/18
MYR - SDF • 1 stop
Cheapest one-way
$220
Typical prices: $291-$456
American Airlines
Sat 1/3
MYR - SDF • 1 stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Allegiant's Bonus bundle includes carry-on and flexibility.
Spirit's Wi-Fi offers gate-to-gate connectivity.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
United Airlines
Cheapest • from $300 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
May
Cheapest • 78% price drop
September
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Louisville!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Myrtle Beach to Louisville (MYR-SDF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Louisville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Louisville

Wed, Jan 14 - Sun, Jan 18
United Airlines Logo
1:25 pm - 7:31 pm
MYR
-
SDF
6h 06m1 stop
United Airlines Logo
6:28 am - 12:41 pm
SDF
-
MYR
6h 13m1 stop
$300United Airlines
Wed, Feb 18 - Sat, Feb 21
United Airlines Logo
5:30 pm - 11:59 pm
MYR
-
SDF
6h 29m1 stop
United Airlines Logo
6:15 am - 11:45 am
SDF
-
MYR
5h 30m1 stop
$303United Airlines
Wed, Jan 14 - Sun, Jan 18
United Airlines Logo
1:25 pm - 10:30 pm
MYR
-
SDF
9h 05m2 stops
United Airlines Logo
6:28 am - 12:41 pm
SDF
-
MYR
6h 13m1 stop
$305United Airlines
Thu, Jan 22 - Sun, Jan 25
Delta Logo
10:33 am - 2:36 pm
MYR
-
SDF
4h 03m1 stop
Delta Logo
5:35 am - 9:46 am
SDF
-
MYR
4h 11m1 stop
$309Delta
Thu, Jan 22 - Sun, Jan 25
Southwest Logo
8:15 am - 5:00 pm
MYR
-
SDF
8h 45m2 stops
Southwest Logo
4:15 pm - 9:05 pm
SDF
-
MYR
4h 50m1 stop
$314Southwest
Thu, Jan 1 - Mon, Jan 5
Multiple Airlines Logo
9:54 am - 11:59 pm
MYR
-
SDF
14h 05m1 stop
Multiple Airlines Logo
8:53 pm - 6:08 pm
SDF
-
MYR
21h 15m1 stop
$315Multiple Airlines
Thu, Jan 22 - Sun, Jan 25
Southwest Logo
8:15 am - 5:00 pm
MYR
-
SDF
8h 45m2 stops
Southwest Logo
11:40 am - 9:05 pm
SDF
-
MYR
9h 25m2 stops
$319Southwest
Wed, Feb 18 - Sat, Feb 21
United Airlines Logo
5:30 pm - 11:59 pm
MYR
-
SDF
6h 29m1 stop
United Airlines Logo
5:35 am - 4:32 pm
SDF
-
MYR
10h 57m2 stops
$325United Airlines
Fri, May 8 - Sun, May 10
Delta Logo
6:00 am - 9:32 am
MYR
-
SDF
3h 32m1 stop
Delta Logo
6:05 am - 12:04 pm
SDF
-
MYR
5h 59m1 stop
$327Delta
Thu, Jan 1 - Mon, Jan 5
Multiple Airlines Logo
9:54 am - 8:58 am
MYR
-
SDF
23h 04m2 stops
Multiple Airlines Logo
8:53 pm - 6:08 pm
SDF
-
MYR
21h 15m1 stop
$329Multiple Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Louisville flights

Get data-powered insights and trends into flights from Myrtle Beach to Louisville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to Louisville?

The average price of all round-trip flights from Myrtle Beach to Louisville clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Louisville on a Saturday and more expensive on a Sunday. On your return trip to Myrtle Beach, you should consider flying back on a Monday, and avoid Fridays for better deals.

What is the cheapest month to fly from Myrtle Beach to Louisville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Louisville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Louisville is May, where tickets cost $73 (return) on average. On the other hand, the most expensive months are March and December, where the average cost of round-trip tickets is $665 and $410 respectively.

Can I save money by flying with a layover from Myrtle Beach to Louisville?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $368, prices are generally cheapest when you fly direct.

Expert advice

Expert advice for your flight from Myrtle Beach to Louisville

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Spirit Airlines

Spirit's Big Front Seat offers 20-inch width and 11” extra legroom for added comfort.


Spirit's Wi-Fi offers gate-to-gate connectivity, available across all routes for uninterrupted browsing.

Allegiant Air

Allegiant's Legroom+ provides extra space in exit rows and front seats on select routes.


Allegiant's Bonus bundle includes carry-on, seat selection, and ticket change flexibility.

Our travel experts
Joe Cortez

Joe Cortez

Expert on Spirit Airlines

Joe Cortez

Joe Cortez

Joe Cortez is a seasoned managing editor in aviation with over a decade of industry experience. His work has been featured on prominent platforms such as FlyerTalk and TripSavvy, establishing him as a respected voice in aviation journalism.

Read more
Daniel Scheffler

Daniel Scheffler

Expert on Allegiant Air

Daniel Scheffler

Daniel Scheffler

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Read more

Good to know

Low seasonJanuary
Cheapest flight$220
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 3% increase in price.
Flight from Myrtle Beach to Louisville

When to book flights from Myrtle Beach to Louisville

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Louisville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Louisville

  • What is the cheapest flight from Myrtle Beach to Louisville?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Louisville was $220 for a one-way ticket and $300 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Louisville?

    A passport is not required to fly from Myrtle Beach to Louisville.

  • Which airports will I be using when flying from Myrtle Beach to Louisville?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in Louisville is Louisville Intl.

  • Which aircraft models fly most regularly from Myrtle Beach to Louisville?

    The Airbus A320neo is the aircraft model that flies most regularly on the Myrtle Beach to Louisville flight route.

  • Which airline alliances offer flights from Myrtle Beach to Louisville?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and Louisville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to Louisville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Louisville are Delta and American Airlines. With an average price for the route of $477 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $348 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Louisville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Louisville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Louisville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Louisville from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Louisville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Louisville with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SDF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Louisville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Louisville from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Louisville

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Louisville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Louisville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8005 reviews
7.9Entertainment
7.9Comfort
7.3Food
8.5Crew
8.1Boarding
Airline reviews

Great. I had to modify a flight. That was easy and free. Thank You

10.0 ExcellentOlumuyiwa, Dec 2025
DTW - ATL
Read more Delta reviews

Great. I had to modify a flight. That was easy and free. Thank You

I noticed that the planes seem to be outdated. There was no entertainment per se. Also, the waiting area did not have any working electrical outlets

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Did not understand a single word the attendant said on the pa system. I was glad it was not an emergency.

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

The boarding was as always, the crew tried their best but not enough. The food was a disaster I had dietary restrictions that were half met because the company did not loaded the food for the flight. The entertainment screen was fine but content was not and also they removed the free messaging option from the flight and they charged 30 dollars for that crappy bandwidth. This flight is not worth the cost and the company is going down on quality.

Awful. They won’t help me with anything. I booked on American but they abdicated to Iberia. The ticket was overpriced. Everything negative

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

Everything you need to know for your flight from Myrtle Beach to Louisville

Information on your arrival and departure airports