MYR - SDF

$107 Find Cheap Flights from Myrtle Beach to Louisville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Louisville departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Louisville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Louisville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Louisville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$213
Typical prices: $73-$41
United Airlines
Tue 5/19Wed 5/27
MYR - SDF • 1 stop
Cheapest one-way
$104
Typical prices: $70-$199
Spirit Airlines
Sun 5/31
MYR - SDF • 1 stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
Allegiant's Bonus bundle includes carry-on and flexibility.
Spirit's Wi-Fi offers gate-to-gate connectivity.
Expert advice
Expert advice
Expert advice
Expert advice
Nonstop flights
1 day a week
Sat
You can fly direct with Allegiant Air. Average duration is 0
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top airlines
Cheapest • from $213 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Cheapest • Avg $257 (round-trip)
Shortest trip • 3h 30m (one-way)
Insights
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Flight Deals

Cheap Flights from Myrtle Beach to Louisville (MYR-SDF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Louisville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Louisville

Tue, May 19 - Wed, May 27
United Airlines Logo
3:14 pm - 8:17 pm
MYR
-
SDF
5h 03m
1 stop
United Airlines Logo
6:00 am - 9:59 am
SDF
-
MYR
3h 59m
1 stop
$213United Airlines
Tue, May 19 - Wed, May 27
American Airlines Logo
6:00 am - 12:45 pm
MYR
-
SDF
6h 45m
1 stop
American Airlines Logo
7:38 am - 3:58 pm
SDF
-
MYR
8h 20m
2 stops
$219American Airlines
Tue, Jun 16 - Wed, Jun 24
Multiple Airlines Logo
3:43 pm - 11:30 am
MYR
-
SDF
19h 47m
2 stops
Multiple Airlines Logo
12:20 pm - 8:07 pm
SDF
-
MYR
7h 47m
1 stop
$236Multiple Airlines
Wed, Aug 26 - Mon, Aug 31
Delta Logo
11:00 am - 4:27 pm
MYR
-
SDF
5h 27m
1 stop
Delta Logo
7:30 pm - 11:39 pm
SDF
-
MYR
4h 09m
1 stop
$240Delta
Wed, Aug 26 - Mon, Aug 31
Southwest Logo
8:15 am - 12:40 pm
MYR
-
SDF
4h 25m
1 stop
Southwest Logo
6:45 am - 1:50 pm
SDF
-
MYR
7h 05m
2 stops
$249Southwest
Tue, May 19 - Wed, May 27
American Airlines Logo
2:31 pm - 9:30 pm
MYR
-
SDF
6h 59m
2 stops
American Airlines Logo
7:38 am - 3:58 pm
SDF
-
MYR
8h 20m
2 stops
$254American Airlines
Sat, May 16 - Sat, May 23
Spirit Airlines Logo
6:30 am - 9:28 am
MYR
-
SDF
26h 58m
1 stop
Spirit Airlines Logo
10:33 am - 8:36 pm
SDF
-
MYR
10h 03m
1 stop
$255Spirit Airlines
Thu, May 28 - Sat, May 30
Spirit Airlines Logo
3:43 pm - 9:28 am
MYR
-
SDF
17h 45m
2 stops
Spirit Airlines Logo
10:33 am - 8:36 pm
SDF
-
MYR
10h 03m
1 stop
$257Spirit Airlines
Thu, May 7 - Mon, May 11
Multiple Airlines Logo
6:00 am - 9:28 am
MYR
-
SDF
27h 28m
1 stop
Multiple Airlines Logo
7:48 pm - 2:48 pm
SDF
-
MYR
19h 00m
2 stops
$266Multiple Airlines
Thu, Sep 24 - Mon, Sep 28
Delta Logo
6:45 pm - 11:59 pm
MYR
-
SDF
5h 14m
1 stop
Delta Logo
7:30 pm - 11:39 pm
SDF
-
MYR
4h 09m
1 stop
$267Delta
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Louisville flights

Get data-powered insights and trends into flights from Myrtle Beach to Louisville to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to Louisville?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to Louisville departing in May.

Can I save money by flying with a layover from Myrtle Beach to Louisville?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $366 on average.

Expert advice

Expert advice for your flight from Myrtle Beach to Louisville

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Daniel Scheffler

Daniel Scheffler

Expert on Allegiant Air

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Joe Cortez

Joe Cortez

Expert on Spirit Airlines

Joe Cortez is a seasoned managing editor in aviation with over a decade of industry experience. His work has been featured on prominent platforms such as FlyerTalk and TripSavvy, establishing him as a respected voice in aviation journalism.

Good to know

Low seasonMay
Cheapest flight$104
Best time to beat the crowds with an average 77% drop in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Myrtle Beach to Louisville

When to book flights from Myrtle Beach to Louisville

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Louisville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Louisville

  • What is the cheapest flight from Myrtle Beach to Louisville?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Louisville was $104 for a one-way ticket and $213 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Louisville?

    A passport is not required to fly from Myrtle Beach to Louisville.

  • Which airports will I be using when flying from Myrtle Beach to Louisville?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in Louisville is Louisville Intl.

  • Which aircraft models fly most regularly from Myrtle Beach to Louisville?

    The Airbus A320neo is the aircraft model that flies most regularly on the Myrtle Beach to Louisville flight route.

  • Which airline alliances offer flights from Myrtle Beach to Louisville?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and Louisville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to Louisville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Louisville are Delta and American Airlines. With an average price for the route of $321 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $370 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Louisville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Louisville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Louisville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Louisville from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Louisville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Louisville with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SDF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Louisville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Louisville from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Myrtle Beach to Louisville?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Myrtle Beach Intl to Louisville Intl.
Find which airlines fly direct from Myrtle Beach Intl Airport to Louisville Intl Airport, which days they fly and book direct flights.

Direct departures

Myrtle Beach Intl to Louisville Intl

Saturday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Louisville Intl to Myrtle Beach Intl

Saturday

Allegiant Air

Allegiant Air

See more direct flights

Reviews of the top 3 airlines serving from Myrtle Beach to Louisville

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Louisville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Louisville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8455 reviews
8.1Boarding
7.2Food
7.8Entertainment
7.9Comfort
8.5Crew
Airline reviews

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

10.0 ExcellentJennifer, Apr 2026
ATL - OKC
Read more Delta reviews

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Crew was nice, meal was good. Entertainment had to be rebooted 3 times and still did not work. Turns out there was residue on screen, it needed to be cleaned to prevent the touchscreen buttons from continuously activating. I had entertainment for the last 45 minutes of a 5 hour 45 minute flight. Really unacceptable for first class. Flight attendent indicated your cleaning solution creates this problem. Seems as if this is widely known, you should be using a different product or cleaning better. Really really disappointing which simply added to the wi fi on your planes with reliably never ever works.

The baggage belt was not updated on the Delta App and was displayed on the wrong belt board. Was not expecting this to happen.

The plan was delayed and left DC 90 minutes late. However, it showed a 20 minute delay on the delta app, then a 12 min delay. It turned out to be an hour delay. I found out where the plane was with flightaware. Stop keeping customers in the dark about what is going on.

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

Landed without a gate ready. Plane is extremely old and dirty.

All the amenities was wonderful, if they could keep their prices that low. I'd fly with them all the time.

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

This was a hard flight. 3 delays out of OKC (1 on the Tarmac). Delay in Atlanta coming to Dallas. total travel time was the equivalent of driving from OKC to Atlanta.

Like: flights are on time, good boarding process Can improve: planes are old, improve entertainment and make space more comfortable

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

On time departure and early arrival. Flight attendant very nice.

As we approached Denver, we encountered quite a bit of turbulence. I know this can sometimes be the case as I frequently fly this route but not on American. My gripe: Usually a pilot or co-pilot alerts passengers to the possibility of turbulance ahead of time. This did not occur nor did he communiucate during what was a pretty rough ride.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

Overall a good experience, however Wifi was not working on the flight.

They canceled my flight and never told me. There was no follow up email. I had to buy another ticket the day of.

Easy to get our TSA pre check #added. Flight crew was great and entertaining and we landed early!

Flight was delayed 6plus hours Did not take flight Customer service was terrible Will never fly again and will spread how terrible you are You stink

I didnt have a flight. Kayak must be on drugs because I confirmed with spirit that I had no booked flight.

We were surprised to be charged $99 for a personal item. And of course everything offered on the flight was an additional charge. Other than that the pilot flew and landed the plane well and the attendants and fellow passengers were nice enough.

baggage drop off was a bit much. I felt like I worked for spirit airlines since I did all the work.

Gate changed multiple times. The staff seemed annoyed that we asked for water. We had to pay for the water as well.

It was a full Spirit experience. Got to witness police officers having to deboard a passenger and cost us about an hour of delay. Front seat was spacious and better than expected.

We didn't get on the flight, they canceled our flight and said there was no flights leaving this weekend and sent me our money back.

Horrible company: canceled flights and delayed flights. Spirit canceled my flight from Miami to Philadelphia the day before we were supposed to leave from Philadelphia to Miami, with no explanation. I had to rebook another flight, spending more money and instead of flying from Miami, I had to choose a flight from Fort Lauderdale because there were no direct flights available from Miami. That created additional cost. The flight with Spirit from Fort Lauderdale was scheduled to depart at 6am, so I had to wake up my 3 and 6 years old at 3am to get to the airport in time and then, at 5am while we were at the gate the delayed the flight until 7:45am with again no explanation.

Everything you need to know for your flight from Myrtle Beach to Louisville

Information on your arrival and departure airports