MYR - SDF

$86 Find Cheap Flights from Myrtle Beach to Louisville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Louisville departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Louisville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Louisville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Louisville, as well as popular online travel agencies
Travelers love KAYAK
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Everything you should know

Cheapest round-trip
$280
Overall average: $665
American Airlines
Tue 3/3Sat 3/7
MYR - SDF • 1 stop
Cheapest one-way
$86
Spirit Airlines
Thu 2/12
MYR - SDF • 1 stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Allegiant's Bonus bundle includes carry-on and flexibility.
Spirit's Wi-Fi offers gate-to-gate connectivity.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
American Airlines
Cheapest • from $280 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
May
Cheapest • 78% price drop
September
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Louisville!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Myrtle Beach to Louisville (MYR-SDF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Louisville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Louisville

Tue, Mar 3 - Sat, Mar 7
American Airlines Logo
10:27 am - 4:20 pm
MYR
-
SDF
5h 53m
1 stop
American Airlines Logo
6:00 am - 10:18 am
SDF
-
MYR
4h 18m
1 stop
$280American Airlines
Tue, Mar 3 - Sat, Mar 7
American Airlines Logo
10:26 am - 5:21 pm
MYR
-
SDF
6h 55m
2 stops
American Airlines Logo
5:00 am - 8:20 am
SDF
-
MYR
3h 20m
1 stop
$285American Airlines
Fri, Feb 13 - Fri, Feb 20
Spirit Airlines Logo
9:09 am - 11:05 am
MYR
-
SDF
25h 56m
1 stop
Spirit Airlines Logo
1:19 pm - 8:13 am
SDF
-
MYR
18h 54m
2 stops
$287Spirit Airlines
Tue, Mar 3 - Sat, Mar 7
Southwest Logo
11:05 am - 10:45 pm
MYR
-
SDF
11h 40m
2 stops
Southwest Logo
11:55 am - 7:35 pm
SDF
-
MYR
7h 40m
2 stops
$320Southwest
Fri, Feb 13 - Fri, Feb 20
Spirit Airlines Logo
9:09 am - 11:05 am
MYR
-
SDF
25h 56m
1 stop
Spirit Airlines Logo
1:19 pm - 10:59 am
SDF
-
MYR
21h 40m
1 stop
$328Spirit Airlines
Sun, Feb 8 - Sun, Feb 15
American Airlines Logo
5:29 pm - 10:12 pm
MYR
-
SDF
4h 43m
1 stop
American Airlines Logo
6:00 am - 10:44 am
SDF
-
MYR
4h 44m
1 stop
$357American Airlines
Fri, Feb 13 - Fri, Feb 20
American Airlines Logo
3:17 pm - 11:16 pm
MYR
-
SDF
7h 59m
2 stops
American Airlines Logo
6:10 am - 2:27 pm
SDF
-
MYR
8h 17m
2 stops
$358American Airlines
Sun, Feb 8 - Sun, Feb 15
American Airlines Logo
6:23 am - 4:02 pm
MYR
-
SDF
9h 39m
2 stops
American Airlines Logo
11:38 am - 6:01 pm
SDF
-
MYR
6h 23m
1 stop
$362American Airlines
Sun, Feb 8 - Sun, Feb 15
American Airlines Logo
6:23 am - 4:02 pm
MYR
-
SDF
9h 39m
2 stops
American Airlines Logo
3:49 pm - 11:55 pm
SDF
-
MYR
8h 06m
2 stops
$368American Airlines
Fri, Feb 20 - Mon, Feb 23
United Airlines Logo
1:00 pm - 10:13 pm
MYR
-
SDF
9h 13m
2 stops
United Airlines Logo
6:18 am - 12:19 pm
SDF
-
MYR
6h 01m
1 stop
$373United Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Louisville flights

Get data-powered insights and trends into flights from Myrtle Beach to Louisville to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Louisville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Louisville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Louisville is May, where tickets cost $73 (return) on average. On the other hand, the most expensive months are March and December, where the average cost of round-trip tickets is $665 and $410 respectively.

Can I save money by flying with a layover from Myrtle Beach to Louisville?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $368, prices are generally cheapest when you fly direct.

Expert advice

Expert advice for your flight from Myrtle Beach to Louisville

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Spirit Airlines

Spirit's Big Front Seat offers 20-inch width and 11” extra legroom for added comfort.


Spirit's Wi-Fi offers gate-to-gate connectivity, available across all routes for uninterrupted browsing.

Allegiant Air

Allegiant's Legroom+ provides extra space in exit rows and front seats on select routes.


Allegiant's Bonus bundle includes carry-on, seat selection, and ticket change flexibility.

Our travel experts
Joe Cortez

Joe Cortez

Expert on Spirit Airlines

Joe Cortez

Joe Cortez

Joe Cortez is a seasoned managing editor in aviation with over a decade of industry experience. His work has been featured on prominent platforms such as FlyerTalk and TripSavvy, establishing him as a respected voice in aviation journalism.

Read more
Daniel Scheffler

Daniel Scheffler

Expert on Allegiant Air

Daniel Scheffler

Daniel Scheffler

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Read more

Good to know

Low seasonJanuary
Cheapest flight$86
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 5% increase in price.
Flight from Myrtle Beach to Louisville

When to book flights from Myrtle Beach to Louisville

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Louisville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Louisville

  • What is the cheapest flight from Myrtle Beach to Louisville?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Louisville was $86 for a one-way ticket and $280 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Louisville?

    A passport is not required to fly from Myrtle Beach to Louisville.

  • Which airports will I be using when flying from Myrtle Beach to Louisville?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in Louisville is Louisville Intl.

  • Which aircraft models fly most regularly from Myrtle Beach to Louisville?

    The Airbus A320neo is the aircraft model that flies most regularly on the Myrtle Beach to Louisville flight route.

  • Which airline alliances offer flights from Myrtle Beach to Louisville?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and Louisville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to Louisville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Louisville are Delta and American Airlines. With an average price for the route of $477 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $370 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Louisville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Louisville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Louisville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Louisville from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Louisville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Louisville with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SDF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Louisville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Louisville from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Myrtle Beach to Louisville

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Louisville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Louisville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8066 reviews
7.8Entertainment
8.1Boarding
7.2Food
8.5Crew
7.9Comfort
Airline reviews

No in flight service, no explanation - FC got service, C+ did not, unsure about Economy. No turbulence to speak of, so I guess another way to cut cost, or promote health and well being of Delta employees? Also, boarding in MEM combined zones, and with overhead space already full on both flights after Zone 2/ Diamond, presents a huge challenge to find a space for a bag. Delta, other than point A to B, is no longer reasonable to fly - very poor experiences, not even taking into account the chastising at the gate and rude crews, across the board.

4.0 OkayUros, Jan 2026
MEM - ATL
Read more Delta reviews

No in flight service, no explanation - FC got service, C+ did not, unsure about Economy. No turbulence to speak of, so I guess another way to cut cost, or promote health and well being of Delta employees? Also, boarding in MEM combined zones, and with overhead space already full on both flights after Zone 2/ Diamond, presents a huge challenge to find a space for a bag. Delta, other than point A to B, is no longer reasonable to fly - very poor experiences, not even taking into account the chastising at the gate and rude crews, across the board.

It would have been better if the flight wasn't delayed by 2.5 hours

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

Delta flight Delay for ,more that two hours i.e original flight was 6.30 PM and it starts at 8.45 PM, When we connect Delta team for meal vouchers as it is late arrival in designation,But we did not get it as per delta policy , which is not good for mid night arrival,

Inexperienced boarding crew allowed too many bags on to a full flight and delayed takeoff causing a missed connection and unplanned overnight stay. There was a hotel at the airport but Delta would not pay for it offering only to shuttle me to an area hotel. Never even offerred so much as an apology by anyone working for Delta.

Staff was great! Kind and cordial! Middle seat row 28 seat B has a hump in it. Trays were getting stuck when putting down and up. Good flight

Departure was delayed resulting in me missing my connection. Delta did not autimatically find me another flight.

The seats weren’t reclining even though it wasn’t as exit seat

It was good because we traveled without luggage, carry on only.

I usually get upgraded so my experience is usually amazing. I did not get upgraded this time - which was fine - but the wifi had issues, the monitors were going in & out, & (though not Delta's fault) one of the gentlemen next to me desperately needed a shower.

The seat cushions were very worn so they were extremely uncomfortable.

Delayed, no updates, had a rewards number but was not working

The seats from lax to DFW was so tight that I could not move my legs . No WiFi and had to pay . Not a good selection of entertainment

AA should improve their in air internet & entertainment options. Seems unreasonable to charge $20/hr and should have some form of free connections. The entertainment options are also pretty limited, movies are outdated and the series only show 3-5 episodes.

We were upgraded to First Class and it was a great flight

Amazing I love American. I’ll never fly anyone else if I can help it.

I love American. I’ll never fly anyone else if I can help it.

Flight delay and multiple gate changes including a change near boarding time to another terminal, which in DFW is a pain. Pre-boarding delay and also a further delay on the ground after boarding. About an hour and a half total delay.

On the plus side, crew was attentive, drinks were cold, and in-flight entertainment selection was better than some other airlines. On the negative aide, Plane was delayed almost an hour, either no announcements from the gate crew. Biscoff cookies are gross, appreciate airlines that give a choice. Also, crew had no personality or enthusiasm at all.

Little warm on the plane and delayed for an hour

Everything you need to know for your flight from Myrtle Beach to Louisville

Information on your arrival and departure airports