MYR - SDF

$101 Find Cheap Flights from Myrtle Beach to Louisville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Louisville departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Louisville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Louisville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Louisville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$191
Typical prices: $449-$256
Spirit Airlines
Mon 4/20Fri 4/24
MYR - SDF • 1 stop
Cheapest one-way
$101
Typical prices: $89-$125
Spirit Airlines
Thu 5/7
MYR - SDF • 1 stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
Allegiant's Bonus bundle includes carry-on and flexibility.
Spirit's Wi-Fi offers gate-to-gate connectivity.
Expert advice
Expert advice
Expert advice
Expert advice
Nonstop flights
1 day a week
Sat
You can fly direct with Allegiant Air. Average duration is 0
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top airlines
Cheapest • from $191 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Cheapest • Avg $257 (round-trip)
Shortest trip • 3h 30m (one-way)
Insights
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Flight Deals

Cheap Flights from Myrtle Beach to Louisville (MYR-SDF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Louisville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Louisville

Mon, Apr 20 - Fri, Apr 24
Spirit Airlines Logo
11:52 am - 5:04 pm
MYR
-
SDF
5h 12m
1 stop
Spirit Airlines Logo
6:06 pm - 11:29 pm
SDF
-
MYR
5h 23m
1 stop
$191Spirit Airlines
Mon, Apr 20 - Fri, Apr 24
Multiple Airlines Logo
9:58 am - 5:04 pm
MYR
-
SDF
7h 06m
1 stop
Multiple Airlines Logo
7:48 pm - 8:30 am
SDF
-
MYR
36h 42m
2 stops
$225Multiple Airlines
Mon, Apr 20 - Fri, Apr 24
Spirit Airlines Logo
11:52 am - 5:04 pm
MYR
-
SDF
5h 12m
1 stop
Spirit Airlines Logo
6:06 pm - 3:50 pm
SDF
-
MYR
21h 44m
3 stops
$290Spirit Airlines
Thu, May 7 - Tue, May 12
American Airlines Logo
4:09 pm - 10:08 pm
MYR
-
SDF
5h 59m
1 stop
American Airlines Logo
5:56 am - 12:15 pm
SDF
-
MYR
6h 19m
1 stop
$293American Airlines
Fri, May 22 - Sun, May 24
Multiple Airlines Logo
6:00 am - 8:20 pm
MYR
-
SDF
14h 20m
1 stop
Multiple Airlines Logo
10:33 am - 8:36 pm
SDF
-
MYR
10h 03m
1 stop
$294Multiple Airlines
Wed, Apr 22 - Sun, Apr 26
Spirit Airlines Logo
8:31 pm - 5:04 pm
MYR
-
SDF
20h 33m
2 stops
Spirit Airlines Logo
6:06 pm - 11:29 pm
SDF
-
MYR
5h 23m
1 stop
$327Spirit Airlines
Fri, May 1 - Tue, May 5
Southwest Logo
7:20 pm - 11:45 pm
MYR
-
SDF
4h 25m
1 stop
Southwest Logo
3:45 pm - 8:30 pm
SDF
-
MYR
4h 45m
1 stop
$331Southwest
Wed, Apr 22 - Sun, Apr 26
Spirit Airlines Logo
8:43 pm - 5:04 pm
MYR
-
SDF
20h 21m
2 stops
Spirit Airlines Logo
6:06 pm - 11:29 pm
SDF
-
MYR
5h 23m
1 stop
$336Spirit Airlines
Fri, May 1 - Tue, May 5
Southwest Logo
3:45 pm - 11:45 pm
MYR
-
SDF
8h 00m
2 stops
Southwest Logo
6:20 am - 1:30 pm
SDF
-
MYR
7h 10m
2 stops
$341Southwest
Thu, Apr 30 - Sun, May 3
Spirit Airlines Logo
11:52 am - 5:04 pm
MYR
-
SDF
5h 12m
1 stop
Spirit Airlines Logo
6:06 pm - 11:29 pm
SDF
-
MYR
5h 23m
1 stop
$343Spirit Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Louisville flights

Get data-powered insights and trends into flights from Myrtle Beach to Louisville to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to Louisville?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to Louisville departing in April.

Can I save money by flying with a layover from Myrtle Beach to Louisville?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $346 on average.

Expert advice

Expert advice for your flight from Myrtle Beach to Louisville

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Daniel Scheffler

Daniel Scheffler

Expert on Allegiant Air

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Joe Cortez

Joe Cortez

Expert on Spirit Airlines

Joe Cortez is a seasoned managing editor in aviation with over a decade of industry experience. His work has been featured on prominent platforms such as FlyerTalk and TripSavvy, establishing him as a respected voice in aviation journalism.

Good to know

Low seasonMay
Cheapest flight$101
Best time to beat the crowds with an average 76% drop in price.
Most popular time to fly and prices are also 16% lower on average.
Flight from Myrtle Beach to Louisville

When to book flights from Myrtle Beach to Louisville

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Louisville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Louisville

  • What is the cheapest flight from Myrtle Beach to Louisville?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Louisville was $101 for a one-way ticket and $191 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Louisville?

    A passport is not required to fly from Myrtle Beach to Louisville.

  • Which airports will I be using when flying from Myrtle Beach to Louisville?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in Louisville is Louisville Intl.

  • Which aircraft models fly most regularly from Myrtle Beach to Louisville?

    The Airbus A320neo is the aircraft model that flies most regularly on the Myrtle Beach to Louisville flight route.

  • Which airline alliances offer flights from Myrtle Beach to Louisville?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and Louisville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to Louisville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to Louisville are Delta and American Airlines. With an average price for the route of $321 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $368 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Louisville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Louisville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Louisville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Louisville from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Louisville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Louisville with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SDF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Louisville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Louisville from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Myrtle Beach to Louisville?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Myrtle Beach Intl to Louisville Intl.
Find which airlines fly direct from Myrtle Beach Intl Airport to Louisville Intl Airport, which days they fly and book direct flights.

Direct departures

Myrtle Beach Intl to Louisville Intl

Saturday

Allegiant Air

Allegiant Air

See more direct flights

Direct returns

Louisville Intl to Myrtle Beach Intl

Saturday

Allegiant Air

Allegiant Air

See more direct flights

Reviews of the top 3 airlines serving from Myrtle Beach to Louisville

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Louisville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Louisville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8392 reviews
7.8Entertainment
8.5Crew
7.2Food
7.9Comfort
8.1Boarding
Airline reviews

The crew bent over backwards to thank us for flying and make us comfortable. The food service was quick and efficient. The Captain communicated and said goodbye and thank you as we departed. They really stood out!

10.0 ExcellentKathryn, Apr 2026
JFK - LAX
Read more Delta reviews

The crew bent over backwards to thank us for flying and make us comfortable. The food service was quick and efficient. The Captain communicated and said goodbye and thank you as we departed. They really stood out!

Okay considering we had weather delays which the Pilot notified us of immediately!

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

Flight from Fort Wayne to Atlanta was the smallest in terms of cabin space that I've ever seen. A carry on I've used for 20 years BARELY fit in overhead compartment. I'm 5'10" and felt very cramped. Not the best experience.

I am writing to express my dissatisfaction with the poor service and unprofessional staff we encountered when traveling with an infant. Our flight was delayed, and the gate staff failed to manage the boarding process appropriately. Due to incorrect, unavailable, or missing 'pink tag' stroller and car seat check-in procedures at the gate, we were forced to board last. Furthermore, the gate staff was rude and dismissive, causing significant distress to our infant. To make matters worse, one of our checked items—an infant sleeper/lounger—was returned to us broken. Given the unsafe handling of essential equipment and unprofessional treatment, I expect a prompt resolution regarding compensation for the damaged items.

We departed and landed early which was a nice surprise. The boarding process was slow.

N Everything was perfect from boarding to assistance to baggage in Tampa

Subpar. The seating on the plane is almost unbearable. We are literally touching and/or sitting on each other which is totally unacceptable and shameful. Pilots and crew was very accommodating and friendly.

The boarding was organized and informative but the plane was tight meaning that you were sitting on one another and extremely uncomfortable. It’s disappointing that can’t have common seating comfort on the plane.

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

I'm not sure American is capable of on-time arrivals and departures. When you land at ORD, you almost always get held on the tarmac because your gate is still occupied. I may have missed my connection, but that ended up up being significantly delayed as well. Once again, I finally got home well after midnight.

Same plane as RDU to LGA — internet not working. Pilot issue of some sort at end of prior flight - I was on same plane for my connection. Late/delayed —

Good flight, seated and had a water within 5 minutes. Crew was hospitable.

Message about flight cancelation was received late due to being in the air. No explanation, just canceled and booked on morning flight. We had to stay in the airport overnight because there was no transportation offered to get to the hotel that AA had available. Actual inflight was fine.

I didn't go from Reno to Phoenix I ended up going from Reno to Dallas to Tucson because my flight rebooked because my Amtrak was late I tried notifying you guys I also don't know what you ask me about my flight because you guys didn't book my flight

Delays experienced in boarding/take off due to incoming plane delayed. However, the boarding time/depart time in the app was significantly delayed in providing these updates. Usually not updated until an hour after we should have already boarded. Poorly managed.

Bag drop was very disorganized in Miami. All main cabin passengers were shunted to just a few lanes and they had an equal number of lanes for first class passengers but there was nobody on those lines. They did nothing to bring the main cab and passengers over to the open lines and they just had employees standing there and doing nothing

there are no options s for snack besides cookies would ve nice to have a salty option n

We left at 1030 am pacific from LA and supposed to land at 7 pm Eastern in NY. They made a detour, stopped in Philadelphia and didn’t land till 1130 PM Eastern!!! Worst flight experience with no pilot communication with no explanation as to what was going on. Everyone was very frustrated to say the least.

Going non stop to lax like I paid for. Not stopping in MCI for gas. Too long of delays

The attendant at the gate was not helpful at all and she was rude when we asked why the flight was delayed.

Great just wish they always had WiFi on every flight couldn’t even purchase it

They cancelled my flight with no reason affecting my travel plans and delaying it 24 hours.

a weekend long saga that ultimately led to a canceled trip. totally unreliable.

Everything was horrible. They delayed my flight so I missed my connection flight and I lost my bags. I had to go to the same workers multiple times asking the same questions because everyone kept giving me different answers. One person closed down customer service because he wanted to go on lunch so there was like 30 people just waiting for hours because no one would relieve him.

Landing was technically perfect. What I didn't like is the pricey internet. Both flights with excellent crews. I'm 6 feet 210 pounds and could easily fit in the chair.

Long long delay, no AC while delayed, gate changes, just for the most uncomfortable flight of your life.

Everything was smooth sailing. Great crew, easy flight and was surprised with an upgraded seat. Thank you all!

My first time experience with Spirit Air was not good at all.The reason i did not know to cancel 24Hrs before flight depature you do charge cancellation fee. It's ridiculous policy.Actually you should provide full voucher instead of charging cancellation fee. Confirmation Code# ZNVPHG Thanks Much , Rita S

I truly admired that the last minute flight attendants were willing to come to serve flight # 1465 and think they should be extra compensated. Doesn't have to beonetary a star a permanent position with Spirit as long as she flies etc. They were o so pleasant and accommodating. 😊😊. Please also serve water. Plain unadulterated water 💧! Invest in a filter of your own the cost of bottles are a penny on the dollar and you could have a plug on advertising with labeling. This could be hilarious "WATER TO REFREST THE SPIRIT FROM SPIRIT ITSELF!" - Free idea!😄😄😄. Anyway overall, though a tad late the flight met expectations. Thanks you Spirit, for everything.

Everything you need to know for your flight from Myrtle Beach to Louisville

Information on your arrival and departure airports