MYR - ECP

$174 Find Cheap Flights from Myrtle Beach to Panama City - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$227
Typical prices: $298-$320
Delta
Sat 8/22Sat 8/29
MYR - ECP • 1 stop
Cheapest one-way
$174
Southwest
Fri 9/18
MYR - ECP • 1 stop
Top airlines
Cheapest • from $227 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
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Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and Panama City. You'll need at least 1 connection.
Insights
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Top layover airports
Cheapest • Avg $309 (round-trip)
Shortest trip • 3h 43m (one-way)
Insights
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Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Panama City (MYR-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Panama City

Sat, Aug 22 - Sat, Aug 29
Delta Logo
6:00 am - 8:31 am
MYR
-
ECP
3h 31m
1 stop
Delta Logo
6:00 am - 10:47 am
ECP
-
MYR
3h 47m
1 stop
$227Delta
Sat, Aug 22 - Sat, Aug 29
American Airlines Logo
7:33 pm - 10:40 pm
MYR
-
ECP
4h 07m
1 stop
American Airlines Logo
5:48 pm - 10:38 pm
ECP
-
MYR
3h 50m
1 stop
$279American Airlines
Sat, Aug 22 - Sat, Aug 29
Southwest Logo
7:55 am - 1:55 pm
MYR
-
ECP
7h 00m
1 stop
Southwest Logo
7:15 am - 7:00 pm
ECP
-
MYR
10h 45m
2 stops
$293Southwest
Sat, Aug 22 - Sat, Aug 29
Southwest Logo
7:55 am - 6:10 pm
MYR
-
ECP
11h 15m
2 stops
Southwest Logo
7:15 am - 7:00 pm
ECP
-
MYR
10h 45m
2 stops
$298Southwest
Sat, Aug 22 - Fri, Aug 28
Southwest Logo
11:55 am - 6:05 pm
MYR
-
ECP
7h 10m
1 stop
Southwest Logo
7:05 am - 2:45 pm
ECP
-
MYR
6h 40m
1 stop
$318Southwest
Sat, Aug 22 - Fri, Aug 28
Southwest Logo
11:55 am - 6:05 pm
MYR
-
ECP
7h 10m
1 stop
Southwest Logo
7:05 am - 7:40 pm
ECP
-
MYR
11h 35m
2 stops
$329Southwest
Fri, Sep 25 - Sun, Oct 4
Southwest Logo
2:30 pm - 7:00 pm
MYR
-
ECP
5h 30m
1 stop
Southwest Logo
7:45 am - 12:35 pm
ECP
-
MYR
3h 50m
1 stop
$337Southwest
Fri, Sep 25 - Sun, Oct 4
Southwest Logo
6:40 am - 4:35 pm
MYR
-
ECP
10h 55m
2 stops
Southwest Logo
7:45 am - 12:35 pm
ECP
-
MYR
3h 50m
1 stop
$343Southwest
Sat, Aug 22 - Sat, Aug 29
Southwest Logo
7:55 am - 1:55 pm
MYR
-
ECP
7h 00m
1 stop
Southwest Logo
10:40 am - 4:25 pm
ECP
-
MYR
4h 45m
1 stop
$347Southwest
Sat, Aug 22 - Sat, Aug 29
Southwest Logo
7:55 am - 1:55 pm
MYR
-
ECP
7h 00m
1 stop
Southwest Logo
7:15 am - 7:00 pm
ECP
-
MYR
10h 45m
2 stops
$352Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Panama City flights

Get data-powered insights and trends into flights from Myrtle Beach to Panama City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to Panama City is April, where tickets cost $0 (return) on average. On the other hand, the most expensive months are March and May, where the average cost of round-trip tickets is $633 and $442 respectively.

Good to know

Low seasonJune
Cheapest flight$174
Best time to beat the crowds with an average 24% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Myrtle Beach to Panama City

When to book flights from Myrtle Beach to Panama City

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Panama City

  • What is the cheapest flight from Myrtle Beach to Panama City?

    In the last 5 days, the lowest price for a flight from Myrtle Beach to Panama City was $174 for a one-way ticket and $227 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Panama City?

    A passport is not required to fly from Myrtle Beach to Panama City.

  • Which aircraft models fly most regularly from Myrtle Beach to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Panama City?

    SkyTeam is the only airline alliance operating flights between Myrtle Beach and Panama City.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Myrtle Beach to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8453 reviews
7.2Food
7.8Entertainment
8.1Boarding
7.8Comfort
8.5Crew
Airline reviews

New high end luggage ruined/zippers broken, items missing. All happened on return flight from msp to mso. Do better! Not store bought luggage but high end personalized ogio custom embroidered luggage. Total slap in the face ontop of an extra luggage fee that took me 3 hrs on chat to resolve.

2.0 MediocreAnonymous, Jun 2026
MSP - MCO
Read more Delta reviews

New high end luggage ruined/zippers broken, items missing. All happened on return flight from msp to mso. Do better! Not store bought luggage but high end personalized ogio custom embroidered luggage. Total slap in the face ontop of an extra luggage fee that took me 3 hrs on chat to resolve.

Third flight in two months where the crew was not there. Comfort seating does not guarantee overhead bin space. Passengers with children are allowed on the plane first - if you are flying to and from Orlando, this means half the plane has boarded before you get on. And somehow all the bin space is taken up. 3 out of 5 flights have had issues with equipment or procedure. Some of these instances caused the flight to be delayed because of a "nuisance" light. One time it was a bag that had been brought on board but did not belong to anyone so we had to return to the gate. Last night we were told the "AC" on the plane doesn't work well and we're 10th for take off- because the crew was late - and that it will get cool when we're in the air. Not sure if this is usual, but I didn't think flight crew could jump seat in first class. Movie and TV selection has not been refreshed for several months- flying one to two round trips each month easily exhausts the list of content.

Definitely a southern flavor. Cordiality was evident even though no drinks or snacks were served.

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Overall Good! The weather delayed our takeoff from Atlanta and our arrival in Miami! If Mother Nature can mess up a flight she will do it every time!

I just can’t understand why are you sell to many tickets ???? We had to wait 2 hours before 13 people from our flight take money and go to next day flight!

We checked one bag. That was fast and the agent was fast and super nice. At the gate, boarding was fast and efficient. Flight was uneventful which was great because it was early in the morning and most folks were sleeping. Landing was great. Delta does a really good job of making the flying experience better all around considering you are sitting in such a small space on a plane for several hours. Flight from ALT to Panama City was short and uneventful as well. No entertainment but no need since it was such a short flight.

Everything you need to know for your flight from Myrtle Beach to Panama City

Information on your arrival and departure airports