MYR - ECP

$321 Find Cheap Flights from Myrtle Beach to Panama City

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$321
Typical prices: $280-$353
Delta
Thu 6/4Tue 6/9
MYR - ECP • 1 stop
Top airlines
Delta
Cheapest • from $321 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and Panama City. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Atlanta (ATL)
Cheapest • Avg $354 (round-trip)
Atlanta (ATL)
Shortest trip • 3h 51m (one-way)
Insights
Insights
Insights
Insights
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Panama City (MYR-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Panama City

Thu, Jun 4 - Tue, Jun 9
Delta Logo
7:51 pm - 11:28 pm
MYR
-
ECP
4h 37m
1 stop
Delta Logo
7:45 am - 2:57 pm
ECP
-
MYR
6h 12m
1 stop
$321Delta
Sun, May 10 - Sat, May 16
Delta Logo
7:51 pm - 11:28 pm
MYR
-
ECP
4h 37m
1 stop
Delta Logo
5:29 pm - 11:57 pm
ECP
-
MYR
5h 28m
1 stop
$333Delta
Thu, Jun 4 - Tue, Jun 9
Southwest Logo
2:05 pm - 5:40 pm
MYR
-
ECP
4h 35m
1 stop
Southwest Logo
7:00 am - 8:30 pm
ECP
-
MYR
12h 30m
2 stops
$336Southwest
Thu, Jun 4 - Tue, Jun 9
Southwest Logo
7:25 am - 5:15 pm
MYR
-
ECP
10h 50m
2 stops
Southwest Logo
7:40 am - 6:25 pm
ECP
-
MYR
9h 45m
2 stops
$341Southwest
Sun, Jun 21 - Sat, Jun 27
American Airlines Logo
8:41 pm - 11:40 pm
MYR
-
ECP
3h 59m
1 stop
American Airlines Logo
6:45 pm - 11:50 pm
ECP
-
MYR
4h 05m
1 stop
$368American Airlines
Mon, Mar 23 - Mon, Mar 30
Delta Logo
6:54 pm - 11:04 pm
MYR
-
ECP
5h 10m
1 stop
Delta Logo
6:43 pm - 12:04 am
ECP
-
MYR
4h 21m
1 stop
$424Delta
Sun, May 10 - Sat, May 16
Southwest Logo
3:40 pm - 9:45 pm
MYR
-
ECP
7h 05m
1 stop
Southwest Logo
9:55 am - 8:45 pm
ECP
-
MYR
9h 50m
2 stops
$425Southwest
Wed, Mar 11 - Sun, Mar 15
Delta Logo
2:16 pm - 7:47 pm
MYR
-
ECP
6h 31m
1 stop
Delta Logo
6:43 pm - 12:04 am
ECP
-
MYR
4h 21m
1 stop
$431Delta
Wed, Mar 11 - Sat, Mar 14
Southwest Logo
10:40 am - 8:00 pm
MYR
-
ECP
10h 20m
2 stops
Southwest Logo
12:25 pm - 7:30 pm
ECP
-
MYR
6h 05m
1 stop
$436Southwest
Wed, Mar 11 - Sat, Mar 14
Southwest Logo
10:40 am - 8:00 pm
MYR
-
ECP
10h 20m
2 stops
Southwest Logo
7:25 am - 8:10 pm
ECP
-
MYR
11h 45m
2 stops
$447Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Panama City flights

Get data-powered insights and trends into flights from Myrtle Beach to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to Panama City, Florida?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to Panama City, Florida departing in June.

Good to know

Low seasonSeptember
Cheapest flight$321
Best time to beat the crowds with an average 39% drop in price.
Most popular time to fly with an average 4% increase in price.
Flight from Myrtle Beach to Panama City

When to book flights from Myrtle Beach to Panama City

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Panama City

  • What is the cheapest flight from Myrtle Beach to Panama City?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Panama City was $321 for a round-trip ticket.

  • Do I need a passport to fly between Myrtle Beach and Panama City?

    A passport is not required to fly from Myrtle Beach to Panama City.

  • Which aircraft models fly most regularly from Myrtle Beach to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Panama City?

    SkyTeam is the only airline alliance operating flights between Myrtle Beach and Panama City.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Myrtle Beach to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8242 reviews
7.9Comfort
7.8Entertainment
8.1Boarding
7.2Food
8.5Crew
Airline reviews

We waited an hour on the runway to get a gate in Orlando

2.0 MediocreJason, Feb 2026
ATL - MCO
Read more Delta reviews

We waited an hour on the runway to get a gate in Orlando

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

They took all carry-on luggage from Groups 6 -9 - I was group 5 and waiting in line to board - they made me check my luggage too. That then went to baggage claim and delayed departure from the airport. There was overhead room in my seating area - Delta over reacted. Also, had a gentleman next to me that took up 1/2 my seat.

Sorry I didn't realize I was writing a review for each leg. Please see my previous review - it applies to the entire flight, not just a single leg.

boarded at 5:30 pm, pushed away from gate at 6pm ... takeoff was not until ~6:45pm; disappointing

Paid for wifi that didn't work. No plug in seat to work. No entertainment.

The flight was delayed and oversold. I volunteered to give up my seat for compensation. Thinking I could get a good night's sleep instead of arriving home at 2 am. It took over an hour to get the new reservation confirmed, three different gate attendants, and two red coats. It took even longer to confirm the overnight hotel, and when I arrived, the line was 45 minutes long, with two people checking in, and at least 15 people slowly, very slowly—no food except frozen convenience food, no coupon for food from airlines. Slept, headed back to the airport, and that flight had an equipment change and a gate change just as they were about to board. It took an additional hour to board as they cleaned the plane from storage.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Delta is a good airline. I've never had an issue with Delta. I'll continue to fly with them until they show me that I shouldn't.

Everything you need to know for your flight from Myrtle Beach to Panama City

Information on your arrival and departure airports