MYR - ECP

$208 Find Cheap Flights from Myrtle Beach to Panama City

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Myrtle Beach to Panama City (MYR-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Panama City

Fri, Sep 12 - Mon, Sep 15
Delta Logo
6:55 pm - 11:03 pmMYR-ECP
5h 08m1 stop
Delta Logo
6:54 pm - 11:49 pmECP-MYR
3h 55m1 stop
$208Delta
Find Deal
Fri, Oct 17 - Mon, Oct 20
American Airlines Logo
5:59 pm - 11:44 pmMYR-ECP
6h 45m1 stop
American Airlines Logo
2:40 pm - 9:50 pmECP-MYR
6h 10m1 stop
$263American Airlines
Find Deal
Thu, Sep 11 - Sun, Sep 14
Delta Logo
6:55 pm - 11:03 pmMYR-ECP
5h 08m1 stop
Delta Logo
6:54 pm - 11:49 pmECP-MYR
3h 55m1 stop
$267Delta
Find Deal
Fri, Sep 12 - Mon, Sep 15
Southwest Logo
6:00 pm - 9:00 pmMYR-ECP
4h 00m1 stop
Southwest Logo
7:25 am - 5:10 pmECP-MYR
8h 45m2 stops
$298Southwest
Find Deal
Fri, Sep 12 - Mon, Sep 15
Southwest Logo
7:00 am - 4:55 pmMYR-ECP
10h 55m2 stops
Southwest Logo
6:35 am - 5:10 pmECP-MYR
9h 35m2 stops
$377Southwest
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Mon, Dec 29 - Thu, Jan 1
Southwest Logo
10:25 am - 3:35 pmMYR-ECP
6h 10m1 stop
Southwest Logo
7:15 am - 2:15 pmECP-MYR
6h 00m1 stop
$389Southwest
Find Deal
Mon, Dec 29 - Thu, Jan 1
Southwest Logo
7:00 am - 3:35 pmMYR-ECP
9h 35m2 stops
Southwest Logo
7:15 am - 2:15 pmECP-MYR
6h 00m1 stop
$394Southwest
Find Deal
Fri, Oct 17 - Mon, Oct 20
Southwest Logo
12:45 pm - 10:35 pmMYR-ECP
10h 50m2 stops
Southwest Logo
2:55 pm - 10:20 pmECP-MYR
6h 25m1 stop
$465Southwest
Find Deal
Fri, Oct 17 - Mon, Oct 20
United Airlines Logo
5:57 pm - 1:05 pmMYR-ECP
20h 08m2 stops
United Airlines Logo
5:08 pm - 2:42 pmECP-MYR
20h 34m2 stops
$773United Airlines
Find Deal
Thu, Aug 28 - Mon, Sep 1
United Airlines Logo
4:45 pm - 9:54 amMYR-ECP
42h 09m2 stops
United Airlines Logo
6:30 am - 2:42 pmECP-MYR
31h 12m2 stops
$1,947United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Panama City flights

Get data-powered insights and trends into flights from Myrtle Beach to Panama City to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to Panama City?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to Panama City were found on Delta ($208) and American Airlines ($263).

Good to know

Low seasonSeptember
Cheapest flight$208
Best time to beat the crowds with an average 50% drop in price.
Most popular time to fly and prices are also 50% lower on average.
Flight from Myrtle Beach to Panama City

When to book flights from Myrtle Beach to Panama City

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Panama City

  • What is the cheapest flight from Myrtle Beach to Panama City?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Panama City was $208 for a round-trip ticket.

  • Do I need a passport to fly between Myrtle Beach and Panama City?

    A passport is not required to fly from Myrtle Beach to Panama City.

  • Which aircraft models fly most regularly from Myrtle Beach to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Panama City?

    SkyTeam, oneworld, and Star Alliance are the airline alliances operating flights between Myrtle Beach and Panama City, with SkyTeam being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Myrtle Beach to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7980 reviews
8.5Crew
7.9Entertainment
7.3Food
8.2Boarding
7.9Comfort
Airline reviews

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

8.0 ExcellentJeanne, Aug 2025MSY - JFK
Read more Delta reviews

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

The seats got pretty uncomfortable pretty fast. The armrests are bigger than on other planes, so I had less room in the actual seat. My butt hurt by the end of the flight. :/ comfort was the primary issue. The crew were fantastic!

I believe that a four-hour trip should have a meal. Delta had none.

Great flight with Delta! Boarding was quick and easy, the amenities were solid, and the plane was in great shape. The flight attendants had a fun, lively energy while staying professional. All in all, a smooth trip — even managed to catch up on some rest. Thanks, Delta!

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

There was supposed to be a meal served, but there wasn’t and the major toilet was out of order

They made us board and then deboard due to mechanical issue which delayed the departure by almost 2 hours and we barely made our connecting flight. These quality checks should've been done before boarding not after.

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

this crew didn't care much. bumping carts into seats more times than i care to remember

Everything was fine except the entertainment was not working for half of the flight.

Everything you need to know for your flight from Myrtle Beach to Panama City

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