MYR - ECP

$188 Find Cheap Flights from Myrtle Beach to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 3/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$328
American Airlines
Sun 2/8Wed 2/18
MYR - ECP • 1 stop
Cheapest one-way
$188
Delta
Fri 3/20
MYR - ECP • 1 stop
Top airlines
American Airlines
Cheapest • from $367 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to Panama City (MYR-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Panama City

Sun, Feb 8 - Wed, Feb 18
American Airlines Logo
6:23 am - 11:33 am
MYR
-
ECP
6h 10m
1 stop
American Airlines Logo
2:00 pm - 6:37 pm
ECP
-
MYR
3h 37m
1 stop
$328American Airlines
Mon, Mar 9 - Fri, Mar 13
American Airlines Logo
6:00 am - 10:06 am
MYR
-
ECP
5h 06m
1 stop
American Airlines Logo
7:19 am - 2:27 pm
ECP
-
MYR
6h 08m
1 stop
$344American Airlines
Sun, Feb 1 - Sun, Feb 8
American Airlines Logo
6:23 am - 11:33 am
MYR
-
ECP
6h 10m
1 stop
American Airlines Logo
6:03 pm - 11:15 pm
ECP
-
MYR
4h 12m
1 stop
$367American Airlines
Sat, Feb 14 - Sun, Feb 15
American Airlines Logo
6:23 pm - 11:49 pm
MYR
-
ECP
6h 26m
1 stop
American Airlines Logo
7:19 am - 2:27 pm
ECP
-
MYR
6h 08m
1 stop
$383American Airlines
Sun, Feb 8 - Wed, Feb 18
Southwest Logo
11:05 am - 6:10 pm
MYR
-
ECP
8h 05m
1 stop
Southwest Logo
8:00 am - 7:45 pm
ECP
-
MYR
10h 45m
2 stops
$390Southwest
Sat, Feb 14 - Sun, Feb 15
Southwest Logo
1:20 pm - 9:00 pm
MYR
-
ECP
8h 40m
2 stops
Southwest Logo
7:35 am - 12:35 pm
ECP
-
MYR
4h 00m
1 stop
$394Southwest
Sun, Feb 8 - Wed, Feb 18
Southwest Logo
8:15 am - 6:10 pm
MYR
-
ECP
10h 55m
2 stops
Southwest Logo
8:00 am - 7:45 pm
ECP
-
MYR
10h 45m
2 stops
$395Southwest
Sun, Jun 21 - Sat, Jun 27
American Airlines Logo
8:34 pm - 11:41 pm
MYR
-
ECP
4h 07m
1 stop
American Airlines Logo
2:28 pm - 9:43 pm
ECP
-
MYR
6h 15m
1 stop
$399American Airlines
Sat, Feb 14 - Sun, Feb 15
Southwest Logo
1:20 pm - 9:00 pm
MYR
-
ECP
8h 40m
2 stops
Southwest Logo
7:35 am - 6:00 pm
ECP
-
MYR
9h 25m
2 stops
$400Southwest
Mon, Jan 26 - Fri, Jan 30
Delta Logo
2:19 pm - 5:12 pm
MYR
-
ECP
3h 53m
1 stop
Delta Logo
7:20 am - 1:30 pm
ECP
-
MYR
5h 10m
1 stop
$431Delta
Booking Insights

KAYAK's insights & trends for Myrtle Beach to Panama City flights

Get data-powered insights and trends into flights from Myrtle Beach to Panama City to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to Panama City?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to Panama City were found on American Airlines ($367) and Southwest ($390).

Which airlines fly non-stop between Myrtle Beach and Panama City?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Myrtle Beach to Panama City.

There is just one airline that flies from Myrtle Beach to Panama City direct and that is Delta. The best round-trip deal found from Delta for the route is $207.

Find deals

Good to know

Low seasonSeptember
Cheapest flight$188
Best time to beat the crowds with an average 40% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Myrtle Beach to Panama City

When to book flights from Myrtle Beach to Panama City

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Panama City

  • What is the cheapest flight from Myrtle Beach to Panama City?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Panama City was $188 for a one-way ticket and $328 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Panama City?

    A passport is not required to fly from Myrtle Beach to Panama City.

  • Which aircraft models fly most regularly from Myrtle Beach to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Panama City?

    SkyTeam is the only airline alliance operating flights between Myrtle Beach and Panama City.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Myrtle Beach to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8039 reviews
7.8Entertainment
7.2Food
8.1Boarding
8.5Crew
7.9Comfort
Airline reviews

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

8.0 ExcellentG, Jan 2026
ATL - FLL
Read more Delta reviews

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Delta is a good airline. I've never had an issue with Delta. I'll continue to fly with them until they show me that I shouldn't.

Flight was operated by Virgin Atlantic and it was up to their usual high standard. Minor grips about some issues, but they are really first world issues and as a whole, was an excellent flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The flight was an hour and a half late departing which was inconvenient

Everything you need to know for your flight from Myrtle Beach to Panama City

Information on your arrival and departure airports

Myrtle Beach (MYR)
Panama City (ECP)