MYR - ECP

$257 Find Cheap Flights from Myrtle Beach to Panama City

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Panama City departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$257
American Airlines
Tue 12/9Tue 12/16
MYR - ECP • 1 stop
Cheapest one-way
$264
Delta
Thu 10/16
MYR - ECP • 1 stop
Top airlines
American Airlines
Cheapest • from $257 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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Flight Deals

Cheap Flights from Myrtle Beach to Panama City (MYR-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to Panama City

Tue, Dec 9 - Tue, Dec 16
American Airlines Logo
6:23 am - 11:38 amMYR-ECP
6h 15m1 stop
American Airlines Logo
8:30 am - 2:44 pmECP-MYR
5h 14m1 stop
$257American Airlines
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Tue, Dec 9 - Tue, Dec 16
Southwest Logo
10:45 am - 7:05 pmMYR-ECP
9h 20m1 stop
Southwest Logo
7:15 am - 5:25 pmECP-MYR
9h 10m2 stops
$298Southwest
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Tue, Dec 9 - Tue, Dec 16
Southwest Logo
8:00 am - 7:05 pmMYR-ECP
12h 05m2 stops
Southwest Logo
7:15 am - 5:25 pmECP-MYR
9h 10m2 stops
$303Southwest
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Tue, Mar 17 - Wed, Mar 18
Delta Logo
6:45 pm - 10:42 pmMYR-ECP
4h 57m1 stop
Delta Logo
7:45 am - 1:29 pmECP-MYR
4h 44m1 stop
$317Delta
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Sun, Oct 26 - Thu, Oct 30
Southwest Logo
10:15 am - 12:50 pmMYR-ECP
3h 35m1 stop
Southwest Logo
2:55 pm - 10:20 pmECP-MYR
6h 25m1 stop
$329Southwest
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Tue, Mar 17 - Wed, Mar 18
Delta Logo
6:00 am - 10:17 amMYR-ECP
5h 17m1 stop
Delta Logo
7:05 pm - 11:35 pmECP-MYR
3h 30m1 stop
$337Delta
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Sun, Oct 26 - Thu, Oct 30
Southwest Logo
7:10 am - 12:50 pmMYR-ECP
6h 40m2 stops
Southwest Logo
2:55 pm - 10:20 pmECP-MYR
6h 25m1 stop
$339Southwest
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Fri, Oct 24 - Tue, Oct 28
Delta Logo
10:36 am - 3:20 pmMYR-ECP
5h 44m1 stop
Delta Logo
9:29 am - 1:50 pmECP-MYR
3h 21m1 stop
$411Delta
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Fri, Oct 24 - Tue, Oct 28
United Airlines Logo
4:33 pm - 9:48 pmMYR-ECP
30h 15m2 stops
United Airlines Logo
6:30 am - 1:09 pmECP-MYR
29h 39m2 stops
$906United Airlines
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Mon, Apr 6 - Fri, Apr 10
United Airlines Logo
3:25 pm - 12:37 pmMYR-ECP
22h 12m2 stops
United Airlines Logo
3:10 pm - 2:38 pmECP-MYR
22h 28m2 stops
$1,026United Airlines
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Booking Insights

KAYAK's insights & trends for Myrtle Beach to Panama City flights

Get data-powered insights and trends into flights from Myrtle Beach to Panama City to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Myrtle Beach to Panama City?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Myrtle Beach to Panama City were found on American Airlines ($257) and Southwest ($298).

Which airlines fly non-stop between Myrtle Beach and Panama City?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Myrtle Beach to Panama City.

There is just one airline that flies from Myrtle Beach to Panama City direct and that is Delta. The best round-trip deal found from Delta for the route is $207.

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Good to know

Low seasonSeptember
Cheapest flight$257
Best time to beat the crowds with an average 39% drop in price.
Most popular time to fly with an average 4% increase in price.
Flight from Myrtle Beach to Panama City

When to book flights from Myrtle Beach to Panama City

Are your dates flexible? Find out the best times to travel from Myrtle Beach to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to Panama City

  • What is the cheapest flight from Myrtle Beach to Panama City?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to Panama City was $264 for a one-way ticket and $257 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and Panama City?

    A passport is not required to fly from Myrtle Beach to Panama City.

  • Which aircraft models fly most regularly from Myrtle Beach to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to Panama City?

    SkyTeam is the only airline alliance operating flights between Myrtle Beach and Panama City.

  • How does KAYAK find such low prices on flights from Myrtle Beach to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Myrtle Beach to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7969 reviews
7.9Comfort
7.9Entertainment
7.3Food
8.2Boarding
8.5Crew
Airline reviews

The flight was great. The gate location was way to far away!!!

10.0 ExcellentLauren, Oct 2025JFK - PBI
Read more Delta reviews

The flight was great. The gate location was way to far away!!!

The flight attendant in first class was beyond rude and didn't care at all about her job. AND the gate agent was even worse than the flight attendant for rudeness. She was awful.

Movie selection was meh. Food was great. Crew as always great. I paid for premium because that’s the only way not to feel like a sardine. That’s how economy should be imo. Sadly passengers have to pay an extra $1000 to get what they should at base price but that’s all airlines. The airline industry in general treats passengers as cargo.

Gate agent rushed to fill hot jetway with crowd so it took over 12 minutes to go from gate to plane. Just like a discount airline Pooly prepared cabin and third time that claim of rough air prevented any cabin service. Friends on a Southwest flight at similar time had service.

Cramped seating for me. Luckily it wasn’t a long flight

Lounge in Lagos is terrible, food on board from Lagos to Atlanta was horrible. Only bright spot the cabin crew were awesome.

The staff and the boarding procedure were all amazing . The one flight was not equipped with WIFI which now adays seems odd. All in all the experience was good

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

this crew didn't care much. bumping carts into seats more times than i care to remember

Everything you need to know for your flight from Myrtle Beach to Panama City

Information on your arrival and departure airports

Myrtle Beach (MYR)
Panama City (ECP)

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