MYR - SAN

$153 Find Cheap Flights from Myrtle Beach to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to San Diego departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Diego, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$367
Overall average: $515
United Airlines
Tue 3/31Tue 4/7
MYR - SAN • 1 stop
Cheapest one-way
$153
Typical prices: $220-$329
Multiple Airlines
Mon 3/30
MYR - SAN • 2 stops
Top airlines
United Airlines
Cheapest • from $367 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and San Diego. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Charlotte (CLT)
Cheapest • Avg $474 (round-trip)
St. Louis (STL)
Shortest trip • 6h 35m (one-way)
Insights
Insights
Insights
Insights
When to travel
September
Cheapest • 25% price drop
February
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to San Diego!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to San Diego (MYR-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Diego

Tue, Mar 31 - Tue, Apr 7
United Airlines Logo
3:15 pm - 10:59 pm
MYR
-
SAN
10h 44m
1 stop
United Airlines Logo
10:30 pm - 10:18 am
SAN
-
MYR
8h 48m
1 stop
$367United Airlines
Tue, Mar 31 - Tue, Apr 7
United Airlines Logo
3:15 pm - 10:59 pm
MYR
-
SAN
10h 44m
1 stop
United Airlines Logo
7:40 pm - 2:17 pm
SAN
-
MYR
15h 37m
2 stops
$372United Airlines
Tue, Mar 31 - Tue, Apr 7
American Airlines Logo
6:01 am - 10:57 am
MYR
-
SAN
7h 56m
1 stop
American Airlines Logo
1:03 pm - 11:02 pm
SAN
-
MYR
6h 59m
1 stop
$377American Airlines
Tue, Mar 31 - Tue, Apr 7
United Airlines Logo
3:15 pm - 12:29 am
MYR
-
SAN
12h 14m
2 stops
United Airlines Logo
7:40 pm - 10:18 am
SAN
-
MYR
11h 38m
2 stops
$378United Airlines
Sat, Apr 18 - Sat, Apr 25
Southwest Logo
5:05 pm - 11:15 pm
MYR
-
SAN
9h 10m
1 stop
Southwest Logo
5:25 pm - 9:45 am
SAN
-
MYR
13h 20m
2 stops
$382Southwest
Sun, May 24 - Sat, May 30
Multiple Airlines Logo
9:18 am - 11:48 am
MYR
-
SAN
29h 30m
1 stop
Multiple Airlines Logo
9:59 pm - 8:44 am
SAN
-
MYR
55h 45m
2 stops
$395Multiple Airlines
Sat, Apr 18 - Sat, Apr 25
American Airlines Logo
4:52 pm - 11:56 pm
MYR
-
SAN
10h 04m
1 stop
American Airlines Logo
9:45 pm - 10:26 am
SAN
-
MYR
9h 41m
1 stop
$396American Airlines
Thu, Mar 26 - Wed, Apr 8
Delta Logo
6:54 pm - 11:09 pm
MYR
-
SAN
7h 15m
1 stop
Delta Logo
9:55 pm - 9:33 am
SAN
-
MYR
8h 38m
1 stop
$397Delta
Tue, Mar 31 - Tue, Apr 7
Southwest Logo
3:40 pm - 10:30 pm
MYR
-
SAN
9h 50m
2 stops
Southwest Logo
6:30 am - 5:35 pm
SAN
-
MYR
8h 05m
2 stops
$402Southwest
Wed, Apr 1 - Wed, Apr 8
American Airlines Logo
3:18 pm - 9:07 pm
MYR
-
SAN
8h 49m
1 stop
American Airlines Logo
7:20 pm - 8:24 am
SAN
-
MYR
10h 04m
2 stops
$404American Airlines
Booking Insights

KAYAK's insights & trends for Myrtle Beach to San Diego flights

Get data-powered insights and trends into flights from Myrtle Beach to San Diego to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to San Diego is September, where tickets cost $365 (return) on average. On the other hand, the most expensive months are December and June, where the average cost of round-trip tickets is $627 and $576 respectively.

Good to know

Low seasonDecember
Cheapest flight$153
Best time to beat the crowds but there is an average 27% increase in price.
Most popular time to fly and prices are also 16% lower on average.
Flight from Myrtle Beach to San Diego

When to book flights from Myrtle Beach to San Diego

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to San Diego

  • What is the cheapest flight from Myrtle Beach to San Diego?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to San Diego was $153 for a one-way ticket and $367 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and San Diego?

    A passport is not required to fly from Myrtle Beach to San Diego.

  • Which airports will I be using when flying from Myrtle Beach to San Diego?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in San Diego is San Diego.

  • Which aircraft models fly most regularly from Myrtle Beach to San Diego?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to San Diego?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and San Diego, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to San Diego, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to San Diego are Southwest and Delta. With an average price for the route of $476 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $526 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Myrtle Beach to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4304 reviews
7.0Food
8.1Boarding
7.5Entertainment
8.0Comfort
8.6Crew
Airline reviews

Mediocre. Boarding is now unpleasant. The employees, once friendly and nice, are now regularly speaking sternly to passengers, badgering them to do things right so they can take off on time and gate check bags because they don't have enough overhead bin space. The pretzel snack was crushed flat and broken into even smaller pieces, which happens frequently lately. Drink service was suspended before they reached my row.

4.0 OkayAnonymous, Mar 2026
PHX - LAX
Read more Southwest reviews

Mediocre. Boarding is now unpleasant. The employees, once friendly and nice, are now regularly speaking sternly to passengers, badgering them to do things right so they can take off on time and gate check bags because they don't have enough overhead bin space. The pretzel snack was crushed flat and broken into even smaller pieces, which happens frequently lately. Drink service was suspended before they reached my row.

The charges were ridiculous for an hour flight and the turbulence was very scary.

3 hour delay. Had to change plans and was still delayed.

The flight crew was extremely rude and especially not helpful when our flight was delayed.

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

The lead steward kept singing about "San Francisco" and hotel California---more annoying than humorous....needs work. Flight was smooth and on time.

Still a fan of open seating. Flight was on schedule and arrived on time. The 737 MAX is very comfortable.

San Diego airport is brand new, spacious, airy and very smooth checkin at SW baggage drop.

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

Delays delays delays. Late taking off, late landing, wait for a gate, etc.

There’s not much to say about a one hour flight. This is a connection from LA to RNO that I missed the previous night due to a mechanical check delay on my originating flight from JFK to LAX. The short flight itself was fine. Instructions from the pilot and crew were per usual. The coffee was barely lukewarm, which possibly was purposeful so we would down it quickly. Bags were already on carousel upon reaching baggage claim, which was excellent.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Awesome! On time flight, early arrival, and a complimentary upgrade!

Was forced to check in my small carry on, even though I informed the crew it has very fragile items inside

They double booked seats, the gate staff changed my ticket as I was boarding she went over to the computer and changed it without telling me. She messed up an entire three row section for me and others. Other travelers were outraged but the gate staff were so rude, so condescending saying it wasn't their problem to solve. I would rate this a zero if I could. Will not fly Delta again I'll stick with United and American.

I usually get upgraded so my experience is usually amazing. I did not get upgraded this time - which was fine - but the wifi had issues, the monitors were going in & out, & (though not Delta's fault) one of the gentlemen next to me desperately needed a shower.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

Smooth flight. From the early boarding and all were on board before departure time and arrived early in ONT. Great crew. Thank you!!!!

The flight was significantly delayed for 6.5 hours because of snow. There was no communication once the plane returned to the gate regarding when the flight would resume. Other flights were departing while our flight was being unloaded for reasons unknown. Our flight also seemed out of the queue regarding further deicing, refueling, and waiting to Taxi to the runway.

They are always late and seats was also not having working charger

did not have enough meal for first class passengers so offer us snack

Amazing I love American. I’ll never fly anyone else if I can help it.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

After the door had been closed, the cockpit makes an announcement that catering is running late and it is not the airline's fault. It is their fault in the sense that we had to sit for 2 hours or more when we could have stayed in the terminal. Poor communications between catering and airline. This caused a young man to lose his temper and he went storming out hitting objects. He had complained to the gate agent that he had already waited at the gate 7 hours and when can the airplane leave? Airilnes do a poor job of explaining delays, maintenance issues, etc. whereas being truthful may gain more sympathy or understanding.

We were told the flight was delayed 5 times, then it was moved to the next day.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything you need to know for your flight from Myrtle Beach to San Diego

Information on your arrival and departure airports