MYR - SAN

$176 Find Cheap Flights from Myrtle Beach to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to San Diego departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Diego, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Myrtle Beach to San Diego (MYR-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Diego

Tue, Jul 29 - Mon, Aug 18
Spirit Airlines Logo
8:58 pm - 11:06 pmMYR-SAN
29h 08m3 stops
Spirit Airlines Logo
1:17 pm - 7:45 pmSAN-MYR
27h 28m3 stops
$269Spirit Airlines
Find Deal
Tue, Jul 29 - Mon, Aug 18
Spirit Airlines Logo
2:54 pm - 11:06 pmMYR-SAN
11h 12m2 stops
Spirit Airlines Logo
1:17 pm - 7:45 pmSAN-MYR
27h 28m3 stops
$274Spirit Airlines
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Thu, Jul 31 - Tue, Aug 5
 Logo
4:31 pm - 11:06 pmMYR-SAN
9h 35m2 stops
 Logo
6:15 am - 7:39 amSAN-MYR
22h 24m2 stops
Thu, Jul 31 - Mon, Aug 4
 Logo
4:31 pm - 11:06 pmMYR-SAN
9h 35m2 stops
 Logo
6:15 am - 7:39 amSAN-MYR
22h 24m2 stops
Thu, Aug 21 - Wed, Aug 27
Delta Logo
11:31 am - 6:01 pmMYR-SAN
9h 30m1 stop
Delta Logo
2:00 pm - 11:49 pmSAN-MYR
6h 49m1 stop
$351Delta
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Tue, Jul 29 - Mon, Aug 18
American Airlines Logo
5:50 pm - 10:27 pmMYR-SAN
7h 37m1 stop
American Airlines Logo
7:15 am - 6:28 pmSAN-MYR
8h 13m1 stop
$354American Airlines
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Thu, Aug 21 - Wed, Aug 27
American Airlines Logo
5:23 am - 9:14 amMYR-SAN
6h 51m1 stop
American Airlines Logo
8:18 am - 8:42 pmSAN-MYR
9h 24m2 stops
$356American Airlines
Find Deal
Sun, Aug 31 - Sun, Sep 7
Delta Logo
6:00 am - 9:27 amMYR-SAN
6h 27m1 stop
Delta Logo
10:30 pm - 10:11 amSAN-MYR
8h 41m1 stop
$385Delta
Find Deal
Thu, Jul 31 - Tue, Aug 5
Southwest Logo
7:10 pm - 10:40 pmMYR-SAN
6h 30m1 stop
Southwest Logo
6:25 am - 7:45 pmSAN-MYR
10h 20m1 stop
$389Southwest
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Thu, Jul 31 - Tue, Aug 5
Southwest Logo
12:10 pm - 7:10 pmMYR-SAN
10h 00m2 stops
Southwest Logo
6:25 am - 7:45 pmSAN-MYR
10h 20m1 stop
$394Southwest
Find Deal
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KAYAK's insights & trends for Myrtle Beach to San Diego flights

Get data-powered insights and trends into flights from Myrtle Beach to San Diego to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Myrtle Beach to San Diego?

The average price of all round-trip flights from Myrtle Beach to San Diego clicked on KAYAK for each day over the last 12 months.

When flying from Myrtle Beach to San Diego, you should consider leaving on a Tuesday and avoid Sundays if you are looking for the best rates. For your return to Myrtle Beach, you’ll find the best rates on Tuesdays and the most expensive ones on Sundays.

What is the cheapest month to fly from Myrtle Beach to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to San Diego is August, where tickets cost $379 (return) on average. On the other hand, the most expensive months are June and December, where the average cost of round-trip tickets is $606 and $542 respectively.

How far in advance should I book a flight from Myrtle Beach to San Diego?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Myrtle Beach to San Diego, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Myrtle Beach to San Diego, you should book around 4 weeks before departure. For the absolute cheapest price, our data suggests you should book 9 weeks before departure.

Good to know

Low seasonApril
High seasonAugust
Cheapest flight$176
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly and prices are also 17% lower on average.
Flight from Myrtle Beach to San Diego

When to book flights from Myrtle Beach to San Diego

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to San Diego

  • What is the cheapest flight from Myrtle Beach to San Diego?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to San Diego was $176 for a one-way ticket and $269 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and San Diego?

    A passport is not required to fly from Myrtle Beach to San Diego.

  • Which airports will I be using when flying from Myrtle Beach to San Diego?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in San Diego is San Diego.

  • Which aircraft models fly most regularly from Myrtle Beach to San Diego?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to San Diego?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Myrtle Beach and San Diego, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to San Diego, Delta or Southwest?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to San Diego are Delta and Southwest. With an average price for the route of $442 and an overall rating of 8.0, Delta is the most popular choice. Southwest is also a great choice for the route, with an average price of $492 and an overall rating of 8.0.

  • How does KAYAK find such low prices on flights from Myrtle Beach to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4273 reviews
7.6Entertainment
7.0Food
8.6Crew
8.0Comfort
8.2Boarding
Airline reviews

First time traveling on Southwest since bag fees were implemented. Usual good service. Just more expensive now.

8.0 ExcellentMichael, Jun 2025PHX - SAN
Read more Southwest reviews

First time traveling on Southwest since bag fees were implemented. Usual good service. Just more expensive now.

It was a perfect flight in all aspects! Both legs!

Boarding process, crew were good. But the seats were so uncomfortable that was all I could focus on. I literally had to sit forward so that all 3 of us could fit in row. I will try to avoid Southwest in the future for any flights over 60 minutes.

Great flight, 47 passengers on a 180 seat plane. Stewardess was pleasant and cheerful.

Great experience flying Southwest. The crew was really kind and helpful, and very friendly with our toddler.

Plane late from DC to Austin 30 minutes. Crew made up much of the time enroute to San Diego.

Fine, but how to board on SW versus othrr airlines, is just lame. Goood staff though and all was solid otherwise.

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a not a great airport.

Was as expected. Crowed planes. Too many carryons delaying takeoff. But the ride only took an hour and saved me a lot of time SFO is a hell hole of an airport. It is the new LaGuardia. Everything Cobbled together. Security gates closed. Terri directional signage

I will be flying again Southwest Airlines. Friendly crew, comfortable and affordable.

Not a "Delta" issue, but a JFK issue: We booked a connecting flight with 3 1/2 hours between to clearn immigration and customs. Our inbound flight (BCN to JFK) was on the taxiway 45 minutes which ate into our layover time. Immigtration was insanely quick with the CBP MPC app; however, clearing TSA (again, after we were ALREADY cleared in Spain on the inbound international flight) took over 95 minutes. This left us with 10 minutes before boarding the connecting flight (JFK to SAN) to walk to the far end of Terminal 4 and try to find food. We didn't find any food that could promise to serve us in under 10 minutes so we boarded the Delta flight after coming off a plance and an 8-hour flight knowing that we wouldn't be served any food on the next 5 1/2 hour flight. I feel like Delta needs to put pressure on the JFK TSA to open more screening stations (by our count, we saw only 5 scanners open and a line of - as we said - over 90 minutes. The insult is that we WERE ALREADY SCREENED through TSA, but as you come off one flight into the USA, you have to go through the whole process again. It seems like if you have a connecting flight, there should be a way to pass through immigration and customs without needing to return through TSA.

There are 4 flights in consecutive gates with about the same departure time. Two flights were boarding at the same time. One was delayed or boarding would be happening at the same time. I am not sure what Delta and LAX need to do to have a better layout at the end of Terminal 2

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

The entertainment and wifi mostly didn't work on this flight.

Terrible entertainment system - kept freezing and audio kept cutting out. Snacks were mediocre at best for a 5 hour flight.

I am still upset that my bag was lost on a recent trip to Rome ; we were inconvenienced and out €150 Euros ; delta has refused to reimburse us

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Seats are much much more comfortable than United, which is what I usually fly

If I pay extra for "comfort+" I expect leg room where I can stretch my legs. I was seated with an attendant's seat blocking my feet. Knee space was fine but my feet had less room than the non-"comfort+" seats. Also, don't go cheap on food when you have flights of 3+ hours. It's insulting.

Only one side of the heafphone jack work. Crew was friendly and helpful.

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

Long 5 hour and 45 min flight and only one drink service and cookie snack

One bottle of water and a package of cookies for comfort plus. We had to literally beg a flight attendant for an extra bottle of water later in the flight due to feeling dehydrated.

Flight boarded from Gate 39 at OGG, the farthest gate in the terminal. There were no Hawaiian themed amenities for the flight. The first class service was mediocre at best; I received not special welcome or recognition as an executive platinum member of American Advantage program. The flight attendants were more concerned with their cell phones than saying "thank you" to the passengers as we disembarked. Fortunately, the flight arrived at LAX a few minutes early.

Bigger seats. Board back to front! Disembark front to back!

Extraordinary service in business class, and very good breakfast and snacks. A really lovely flight.

This flight didn’t happen because AA agents didn’t let us board the flight

Everything you need to know for your flight from Myrtle Beach to San Diego

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