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MYR - SAN

$153 Find Cheap Flights from Myrtle Beach to San Diego - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$305
Typical prices: $461-$599
American Airlines
Sat 1/13Fri 1/19
MYR - SAN • 1 stop
Cheapest one-way
$153
Typical prices: $209-$338
Delta
Sun 11/4
MYR - SAN • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and San Diego. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
February
Cheapest • 27% price drop
March
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Chicago Midway (MDW)
Cheapest • Avg $466 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 7h 23m (one-way)
Insights
Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to San Diego (MYR-SAN)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Diego

Wed, Jan 13 - Tue, Jan 19
American Airlines Logo
6:12 am - 1:08 pmMYR  Myrtle Beach Intl-SAN San Diego
9h 56m1 stop Charlotte Douglas
American Airlines Logo
6:15 am - 4:20 pmSAN  San Diego-MYR Myrtle Beach Intl
7h 05m1 stop Charlotte Douglas
$305American Airlines
Wed, Jan 13 - Tue, Jan 19
Delta Logo
6:00 am - 1:08 pmMYR  Myrtle Beach Intl-SAN San Diego
10h 08m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:40 pm - 10:08 amSAN  San Diego-MYR Myrtle Beach Intl
8h 28m1 stop Atlanta Hartsfield-Jackson
$305Delta
Wed, Jan 13 - Tue, Jan 19
American Airlines Logo
8:07 am - 3:34 pmMYR  Myrtle Beach Intl-SAN San Diego
10h 27m2 stops Charlotte Douglas Phoenix Sky Harbor Intl
American Airlines Logo
6:15 am - 4:20 pmSAN  San Diego-MYR Myrtle Beach Intl
7h 05m1 stop Charlotte Douglas
$359American Airlines
Fri, Nov 13 - Sat, Nov 21
American Airlines Logo
7:00 am - 1:28 pmMYR  Myrtle Beach Intl-SAN San Diego
9h 28m1 stop Charlotte Douglas
American Airlines Logo
10:35 pm - 10:20 amSAN  San Diego-MYR Myrtle Beach Intl
8h 45m1 stop Charlotte Douglas
$374American Airlines
Wed, Jan 13 - Mon, Jan 18
Delta Logo
4:30 pm - 11:03 pmMYR  Myrtle Beach Intl-SAN San Diego
9h 33m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:40 pm - 10:08 amSAN  San Diego-MYR Myrtle Beach Intl
8h 28m1 stop Atlanta Hartsfield-Jackson
$376Delta
Wed, Jan 13 - Tue, Jan 19
Delta Logo
6:00 am - 1:08 pmMYR  Myrtle Beach Intl-SAN San Diego
10h 08m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:40 pm - 10:08 amSAN  San Diego-MYR Myrtle Beach Intl
8h 28m1 stop Atlanta Hartsfield-Jackson
$391Delta
Thu, Dec 10 - Tue, Dec 15
Southwest Logo
8:10 am - 2:30 pmMYR  Myrtle Beach Intl-SAN San Diego
9h 20m1 stop Baltimore/Washington
Southwest Logo
8:15 am - 7:20 pmSAN  San Diego-MYR Myrtle Beach Intl
8h 05m2 stops Las Vegas Harry Reid Intl Nashville Intl
$424Southwest
Tue, Oct 20 - Sat, Oct 24
United Airlines Logo
5:00 pm - 10:41 pmMYR  Myrtle Beach Intl-SAN San Diego
8h 41m1 stop Chicago O'Hare Intl
United Airlines Logo
3:56 pm - 10:21 amSAN  San Diego-MYR Myrtle Beach Intl
15h 25m2 stops San Francisco Newark
$424United Airlines
Fri, Dec 11 - Wed, Dec 16
Southwest Logo
1:40 pm - 6:20 pmMYR  Myrtle Beach Intl-SAN San Diego
7h 40m1 stop Baltimore/Washington
Southwest Logo
6:15 am - 7:20 pmSAN  San Diego-MYR Myrtle Beach Intl
10h 05m2 stops Las Vegas Harry Reid Intl Nashville Intl
$426Southwest
Tue, Oct 20 - Sat, Oct 24
United Airlines Logo
10:23 am - 8:08 pmMYR  Myrtle Beach Intl-SAN San Diego
12h 45m2 stops Washington, D.C. Dulles Intl Los Angeles
United Airlines Logo
7:41 pm - 10:21 amSAN  San Diego-MYR Myrtle Beach Intl
11h 40m2 stops San Francisco Newark
$429United Airlines
Booking Insights

Price, demand and travel trends for Myrtle Beach to San Diego flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Myrtle Beach to San Diego?

Round-trip flights from Myrtle Beach to San Diego typically range from $461 to $599. The lowest price found in the past 5 days was $305, on American Airlines.

What's the cheapest day of the week to fly from Myrtle Beach to San Diego?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Myrtle Beach to San Diego. It’s 8% cheaper than the average day, while Saturday is the most expensive, with prices 16% higher.

What’s the cheapest month to fly from Myrtle Beach to San Diego?

•February is the cheapest month to fly from Myrtle Beach to San Diego at $368 round-trip.
•December ($606) and October ($586) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 64% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Myrtle Beach to San Diego flights

Low season

September

Cheapest flight

$153
Beat the crowds with an average 51% drop in travelers.
The most popular month to fly with an average 37% increase in travelers.
One-way flight from Myrtle Beach to San Diego

When to book flights from Myrtle Beach to San Diego

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Myrtle Beach to San Diego flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Myrtle Beach to San Diego?

    Two cabin classes are available on flights from Myrtle Beach to San Diego:

    • Economy Class
    • First Class

  • How long is a flight from Myrtle Beach to San Diego?

    A nonstop flight from Myrtle Beach to San Diego takes 00m, covering 2,199 miles.

  • Do I need a passport to fly from Myrtle Beach to San Diego?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Myrtle Beach to San Diego flight?

    Round-trip flights from Myrtle Beach to San Diego range from $461 to $599, with an average of $504 over the past 12 months. Anything below $461 counts as a good deal.

  • Have flight prices from Myrtle Beach to San Diego changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $305 to $2,318. That means the highest observed fare was about 8x higher than the lowest one.

  • How are flight prices from Myrtle Beach to San Diego looking right now?

    One-way fares from Myrtle Beach to San Diego are currently lower than usual. Average one-way flight prices are about $189, which is 29% below the typical average for this route.

  • What car rental options are available at San Diego Airport (SAN)?

    San Diego Airport (SAN) hosts 5 major car rental companies, with daily rates starting from around $14 for economy cars. Top options include:

    • Dollar
    • Payless
    • Europcar
    • Thrifty
    • Fox

  • Which airports can I use when flying from Myrtle Beach to San Diego?

    Flights from Myrtle Beach to San Diego usually depart from Myrtle Beach Intl (MYR) and arrive at San Diego (SAN).

  • Which airports do connecting flights from Myrtle Beach to San Diego pass through?

    One-stop flights from Myrtle Beach to San Diego most commonly connect through:

    • Charlotte Douglas (CLT) - 50% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 34% of one-stop connections
    • Dallas/Fort Worth (DFW) - 9% of one-stop connections
    • Nashville Intl (BNA) - 3% of one-stop connections

  • Can I save money by using flexible dates for flights from Myrtle Beach to San Diego?

    Yes. Flexible dates can save you up to 21% on flights from Myrtle Beach to San Diego. Tuesday is the cheapest departure day at $466 round-trip on average, while Saturday is the most expensive at $586, a difference of $120.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Myrtle Beach to San Diego?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 7h 23m, compared with 7h 24m via Dallas/Fort Worth (DFW) and 7h 33m via Charlotte Douglas (CLT).

  • What is the time difference between Myrtle Beach and San Diego?

    San Diego is 3 hours behind Myrtle Beach (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in San Diego?

    Some of the most popular sights in San Diego are Gaslamp Quarter, San Diego Convention Center and SeaWorld San Diego. These are among the most viewed places in San Diego on KAYAK.

Your guide to booking Myrtle Beach to San Diego flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Saturday. On this route, Tuesday flights average $466, about $120 less than Saturday fares (20% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Myrtle Beach to San Diego trip for February. Fares historically average $368 round-trip in that month - typically $238 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to San Diego Airport.

    • Courtyard by Marriott San Diego Downtown Little Italy
    • Bay Club Hotel & Marina
    • Sheraton San Diego Resort

More options for your flight from Myrtle Beach to San Diego

Complete your trip to San Diego with a hotel stay or car rental

Car rentals in San Diego
Hotels in San Diego
Vacations in San Diego