MYR - SAN

$123 Find Cheap Flights from Myrtle Beach to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to San Diego departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Diego, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$311
Overall average: $532
American Airlines
Tue 3/10Thu 3/12
MYR - SAN • 1 stop
Cheapest one-way
$123
Typical prices: $281-$374
Multiple Airlines
Sun 2/1
MYR - SAN • 2 stops
Top airlines
American Airlines
Cheapest • from $311 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
September
Cheapest • 30% price drop
May
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Diego!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to San Diego (MYR-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Diego

Tue, Mar 10 - Thu, Mar 12
American Airlines Logo
6:01 am - 10:57 am
MYR
-
SAN
7h 56m1 stop
American Airlines Logo
10:43 pm - 8:31 am
SAN
-
MYR
6h 48m1 stop
$311American Airlines
Tue, Mar 10 - Thu, Mar 12
American Airlines Logo
10:26 am - 6:02 pm
MYR
-
SAN
10h 36m2 stops
American Airlines Logo
10:00 pm - 8:31 am
SAN
-
MYR
7h 31m1 stop
$316American Airlines
Tue, Mar 10 - Thu, Mar 12
Delta Logo
6:54 pm - 11:09 pm
MYR
-
SAN
7h 15m1 stop
Delta Logo
10:30 pm - 9:38 am
SAN
-
MYR
8h 08m1 stop
$320Delta
Thu, Jan 29 - Mon, Feb 2
Delta Logo
2:19 pm - 8:37 pm
MYR
-
SAN
9h 18m1 stop
Delta Logo
10:30 pm - 9:46 am
SAN
-
MYR
8h 16m1 stop
$343Delta
Thu, Jan 29 - Mon, Feb 2
American Airlines Logo
1:53 pm - 8:36 pm
MYR
-
SAN
9h 43m1 stop
American Airlines Logo
9:21 am - 11:15 pm
SAN
-
MYR
10h 54m2 stops
$348American Airlines
Thu, Feb 12 - Tue, Feb 17
American Airlines Logo
5:10 am - 11:17 am
MYR
-
SAN
9h 07m1 stop
American Airlines Logo
9:44 am - 10:56 pm
SAN
-
MYR
10h 12m2 stops
$354American Airlines
Fri, Feb 27 - Wed, Mar 4
Southwest Logo
10:35 am - 4:15 pm
MYR
-
SAN
8h 40m1 stop
Southwest Logo
9:45 pm - 10:00 am
SAN
-
MYR
9h 15m1 stop
$363Southwest
Fri, Feb 27 - Wed, Mar 4
Southwest Logo
1:00 pm - 8:10 pm
MYR
-
SAN
10h 10m2 stops
Southwest Logo
9:45 pm - 10:00 am
SAN
-
MYR
9h 15m1 stop
$368Southwest
Wed, Feb 11 - Sun, Feb 15
Delta Logo
4:00 pm - 10:45 pm
MYR
-
SAN
9h 45m1 stop
Delta Logo
10:20 pm - 9:45 am
SAN
-
MYR
8h 25m1 stop
$372Delta
Fri, Feb 27 - Wed, Mar 4
Southwest Logo
8:00 am - 2:35 pm
MYR
-
SAN
9h 35m2 stops
Southwest Logo
7:40 pm - 10:00 am
SAN
-
MYR
11h 20m2 stops
$374Southwest
Booking Insights

KAYAK's insights & trends for Myrtle Beach to San Diego flights

Get data-powered insights and trends into flights from Myrtle Beach to San Diego to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Myrtle Beach to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to San Diego is September, where tickets cost $348 (return) on average. On the other hand, the most expensive months are December and June, where the average cost of round-trip tickets is $627 and $576 respectively.

Good to know

Low seasonDecember
Cheapest flight$123
Best time to beat the crowds but there is an average 26% increase in price.
Most popular time to fly and prices are also 23% lower on average.
Flight from Myrtle Beach to San Diego

When to book flights from Myrtle Beach to San Diego

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to San Diego

  • What is the cheapest flight from Myrtle Beach to San Diego?

    In the last 3 days, the lowest price for a flight from Myrtle Beach to San Diego was $123 for a one-way ticket and $311 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and San Diego?

    A passport is not required to fly from Myrtle Beach to San Diego.

  • Which airports will I be using when flying from Myrtle Beach to San Diego?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in San Diego is San Diego.

  • Which aircraft models fly most regularly from Myrtle Beach to San Diego?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to San Diego?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and San Diego, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to San Diego, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to San Diego are Southwest and Delta. With an average price for the route of $476 and an overall rating of 8.0, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $478 and an overall rating of 7.9.

  • How does KAYAK find such low prices on flights from Myrtle Beach to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4249 reviews
7.0Food
8.1Boarding
7.5Entertainment
8.0Comfort
8.6Crew
Airline reviews

The flight crew was extremely rude and especially not helpful when our flight was delayed.

2.0 MediocreMatthew, Jan 2026
DAL - SAN
Read more Southwest reviews

The flight crew was extremely rude and especially not helpful when our flight was delayed.

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

The lead steward kept singing about "San Francisco" and hotel California---more annoying than humorous....needs work. Flight was smooth and on time.

Still a fan of open seating. Flight was on schedule and arrived on time. The 737 MAX is very comfortable.

San Diego airport is brand new, spacious, airy and very smooth checkin at SW baggage drop.

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

Delays delays delays. Late taking off, late landing, wait for a gate, etc.

Connecting flight is on time and boarding was a breeze!

Very smooth checking in our luggage with a super pleasant SW agent. I enjoyed a fun entertaining movie.

First time traveling on Southwest since bag fees were implemented. Usual good service. Just more expensive now.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

Flight was too crowded and seats are too small, especially since passengrs are getting larger. Having a middle seat is ALWAYS tough! Woman on my left was large & kept creeping in to my space. Flight personnel were great! Have more savory rather than sweet snacks please.

The crew took good care of us. The flight from ATL to SFO is a longer one, and there were multiple beverage offerings. I like the 757's that Delta uses. Good airplane that is comfortable. I do wish Delta would separate Priority boarding from the better seats. I would gladly take a smaller seat in an open row than be jammed into Comfort just to get priority boarding, just to make sure I don't have to check a bag.

Gate agent rushed to fill hot jetway with crowd so it took over 12 minutes to go from gate to plane. Just like a discount airline Pooly prepared cabin and third time that claim of rough air prevented any cabin service. Friends on a Southwest flight at similar time had service.

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

Food was surprisingly good but the WiFi was not great

My flight was extremely cold. I had a jacket and a cover was left in each seat. The cover was extremely thin and I have a disability, fibromyalgia and arthrithis and AC air is the worst. I closed my vent and my husbands vent and it still was frigid. I asked the attendant if I could get another cover and she quickly almost dismissively and totally unconcerned stating, (I quote) (one per chair) and walked off so quickly that I didn't get a chance to explain to her that I literally have adisability. I didnt want to make a seen so I set on that flight for over 5 hours in pain, joints locking up and extremely uncomfortable. When my fibromyalgia flares up my joints not only ache but they will lock up also and it takes me days to get back to my regular self even though I take medication for it. I felt like it would not have hurt anyone at all for her to just give me an extra cover because I'm sure they have all types of medical issues in people that fly every day.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

After the door had been closed, the cockpit makes an announcement that catering is running late and it is not the airline's fault. It is their fault in the sense that we had to sit for 2 hours or more when we could have stayed in the terminal. Poor communications between catering and airline. This caused a young man to lose his temper and he went storming out hitting objects. He had complained to the gate agent that he had already waited at the gate 7 hours and when can the airplane leave? Airilnes do a poor job of explaining delays, maintenance issues, etc. whereas being truthful may gain more sympathy or understanding.

We were told the flight was delayed 5 times, then it was moved to the next day.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Loved the crew . Absolutely no complaints. Except for luggage lost

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

We are too tired and frustrated to comment politely at this point

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Everything you need to know for your flight from Myrtle Beach to San Diego

Information on your arrival and departure airports