MYR - SAN

$182 Find Cheap Flights from Myrtle Beach to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to San Diego departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Myrtle Beach to San Diego, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$363
Typical prices: $408-$484
American Airlines
Wed 7/29Tue 8/4
MYR - SAN • 1 stop
Cheapest one-way
$182
Typical prices: $201-$401
Southwest
Wed 9/9
MYR - SAN • 1 stop
Top airlines
Cheapest • from $363 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Myrtle Beach and San Diego. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $466 (round-trip)
Shortest trip • 6h 35m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 30% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Diego!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Myrtle Beach to San Diego (MYR-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Myrtle Beach to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Myrtle Beach to San Diego

Wed, Jul 29 - Tue, Aug 4
American Airlines Logo
4:16 pm - 9:45 pm
MYR
-
SAN
8h 29m
1 stop
American Airlines Logo
9:25 pm - 9:40 am
SAN
-
MYR
9h 15m
1 stop
$363American Airlines
Wed, Nov 11 - Sat, Nov 14
United Airlines Logo
11:30 am - 9:26 pm
MYR
-
SAN
12h 56m
2 stops
United Airlines Logo
8:45 pm - 10:20 am
SAN
-
MYR
10h 35m
1 stop
$368United Airlines
Tue, Aug 4 - Thu, Aug 13
American Airlines Logo
4:16 pm - 9:45 pm
MYR
-
SAN
8h 29m
1 stop
American Airlines Logo
12:47 pm - 10:38 pm
SAN
-
MYR
6h 51m
1 stop
$369American Airlines
Wed, Nov 11 - Mon, Nov 16
United Airlines Logo
11:30 am - 8:33 pm
MYR
-
SAN
12h 03m
2 stops
United Airlines Logo
8:45 pm - 10:20 am
SAN
-
MYR
10h 35m
1 stop
$374United Airlines
Mon, Aug 17 - Thu, Aug 20
Delta Logo
2:18 pm - 8:58 pm
MYR
-
SAN
9h 40m
1 stop
Delta Logo
10:17 pm - 10:38 am
SAN
-
MYR
9h 21m
1 stop
$375Delta
Tue, Aug 11 - Thu, Aug 20
Southwest Logo
2:25 pm - 7:35 pm
MYR
-
SAN
8h 10m
1 stop
Southwest Logo
6:45 am - 5:35 pm
SAN
-
MYR
7h 50m
1 stop
$377Southwest
Wed, Jul 29 - Tue, Aug 4
Southwest Logo
7:00 am - 2:50 pm
MYR
-
SAN
10h 50m
2 stops
Southwest Logo
6:20 am - 7:20 pm
SAN
-
MYR
10h 00m
2 stops
$380Southwest
Tue, Aug 11 - Thu, Aug 20
Southwest Logo
2:25 pm - 10:00 pm
MYR
-
SAN
10h 35m
2 stops
Southwest Logo
6:45 am - 5:35 pm
SAN
-
MYR
7h 50m
1 stop
$382Southwest
Tue, Aug 11 - Sat, Aug 22
Southwest Logo
2:25 pm - 10:00 pm
MYR
-
SAN
10h 35m
2 stops
Southwest Logo
6:35 am - 7:35 pm
SAN
-
MYR
10h 00m
2 stops
$387Southwest
Tue, Aug 11 - Sat, Aug 22
Delta Logo
6:00 am - 9:26 am
MYR
-
SAN
6h 26m
1 stop
Delta Logo
10:25 pm - 10:47 am
SAN
-
MYR
9h 22m
1 stop
$391Delta
Booking Insights

KAYAK's insights & trends for Myrtle Beach to San Diego flights

Get data-powered insights and trends into flights from Myrtle Beach to San Diego to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Myrtle Beach to San Diego?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Myrtle Beach to San Diego departing in July.

What is the cheapest month to fly from Myrtle Beach to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Myrtle Beach to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Myrtle Beach to San Diego is August, where tickets cost $350 (return) on average. On the other hand, the most expensive months are December and June, where the average cost of round-trip tickets is $642 and $565 respectively.

Good to know

Low seasonDecember
Cheapest flight$182
Best time to beat the crowds but there is an average 28% increase in price.
Most popular time to fly and prices are also 21% lower on average.
Flight from Myrtle Beach to San Diego

When to book flights from Myrtle Beach to San Diego

Are your dates flexible? Find out the best times to travel from Myrtle Beach to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Myrtle Beach to San Diego

  • What is the cheapest flight from Myrtle Beach to San Diego?

    In the last 5 days, the lowest price for a flight from Myrtle Beach to San Diego was $182 for a one-way ticket and $363 for a round-trip.

  • Do I need a passport to fly between Myrtle Beach and San Diego?

    A passport is not required to fly from Myrtle Beach to San Diego.

  • Which airports will I be using when flying from Myrtle Beach to San Diego?

    Myrtle Beach airport is called Myrtle Beach Intl and the only airport in San Diego is San Diego.

  • Which aircraft models fly most regularly from Myrtle Beach to San Diego?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Myrtle Beach to San Diego?

    SkyTeam, and oneworld are the airline alliances operating flights between Myrtle Beach and San Diego, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Myrtle Beach to San Diego, Southwest or Delta?

    The two airlines most popular with KAYAK users for flights from Myrtle Beach to San Diego are Southwest and Delta. With an average price for the route of $522 and an overall rating of 7.9, Southwest is the most popular choice. Delta is also a great choice for the route, with an average price of $497 and an overall rating of 7.8.

  • How does KAYAK find such low prices on flights from Myrtle Beach to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Myrtle Beach with another airline. Booking your flights between Myrtle Beach and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Myrtle Beach to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Myrtle Beach to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Myrtle Beach to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4246 reviews
8.0Comfort
8.6Crew
8.1Boarding
7.0Food
7.5Entertainment
Airline reviews

3 hour delay. Had to change plans and was still delayed.

2.0 MediocreAnonymous, Jan 2026
SFO - SAN
Read more Southwest reviews

3 hour delay. Had to change plans and was still delayed.

The flight crew was extremely rude and especially not helpful when our flight was delayed.

Delays delays delays. Late taking off, late landing, wait for a gate, etc.

First time traveling on Southwest since bag fees were implemented. Usual good service. Just more expensive now.

Plane late from DC to Austin 30 minutes. Crew made up much of the time enroute to San Diego.

Our first flight was so delayed that we had 10 mins to board the next one. We requested if the flight attendant could allow us off there plane first and they denied our request even though I have seen this done before. Luck was on our side that we didn’t miss our next flight.

Everything was great except for the in-flight wifi that wasn't working.

It was great! The new boeing has much more space and charging ports!

Took a little longer than normal, but the process is clear and easy to understand.

Baggage check in would have been better if the service clerk told the other clerk that she was merging her two long lines of customers with her line so she could move luggage. Instead she only told the customers. When I told the agent and ask if she could direct who is next in line so we weren’t trying to cut in front of each other she said it’s not her problem and she can’t work three lines. I was shocked. Understood that they were working more than their share but some organization so the customers aren’t getting upset at each other would have gone a long way

Crew was real good, flight was smooth and came in early.

Gate agent rushed to fill hot jetway with crowd so it took over 12 minutes to go from gate to plane. Just like a discount airline Pooly prepared cabin and third time that claim of rough air prevented any cabin service. Friends on a Southwest flight at similar time had service.

Not a "Delta" issue, but a JFK issue: We booked a connecting flight with 3 1/2 hours between to clearn immigration and customs. Our inbound flight (BCN to JFK) was on the taxiway 45 minutes which ate into our layover time. Immigtration was insanely quick with the CBP MPC app; however, clearing TSA (again, after we were ALREADY cleared in Spain on the inbound international flight) took over 95 minutes. This left us with 10 minutes before boarding the connecting flight (JFK to SAN) to walk to the far end of Terminal 4 and try to find food. We didn't find any food that could promise to serve us in under 10 minutes so we boarded the Delta flight after coming off a plance and an 8-hour flight knowing that we wouldn't be served any food on the next 5 1/2 hour flight. I feel like Delta needs to put pressure on the JFK TSA to open more screening stations (by our count, we saw only 5 scanners open and a line of - as we said - over 90 minutes. The insult is that we WERE ALREADY SCREENED through TSA, but as you come off one flight into the USA, you have to go through the whole process again. It seems like if you have a connecting flight, there should be a way to pass through immigration and customs without needing to return through TSA.

Rough day of travel all the way around. Wrong info given to us multiple times and mistakes in their booking making our trip 10 hours longer than planned. I’m bummed because I fly Delta all the time and love them. Mistakes happen. Just bummed that this was a rare trip our whole family was traveling together.

It was good until there was a 3 hour delay because there was not any pilots to fly the plane.

Everything was very good other than I had selected a specific seat when I booked the flight and they changed it once I checked-in the day before my flight. I was still in first class but lost my aisle seat for a window seat. Being tall, the aisle offers more comfort so I always select an aisle seat.

Flight diverted in SD. Later take off in Seattle by 1.3hrs

Was a great smooth flight from Detroit to San Diego.

The boarding process was terrible especially with an indirect flight Chicago to Seattle to San Diego was terrible talking about we overbooked a flight idk if I’d take this airline ever again we got off our flight from Chicago to Seattle and we traveled for business and they told us our connecting flight was over booked and their was no seats asking people to take a delayed next flight and they don’t tell anyone coughing to wear masks seats 30A-B were terrible during the flight no one wants to sit next to people coughing all around I don’t want to be sick traveling for work or get sick anytime it’s very upsetting the staff doesn’t take this stuff serious to tell them to wear masks when they see people coughing and sneezing

They made us check our bag…. Even though there was plenty of space up top… and then proceeded to shatter by brand new luggage 😞

Delayed for mechanical and no updates on what was happening and how long the delay might be.

We are too tired and frustrated to comment politely at this point

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

The service and food needs to improve to catch up with other international flights

The flight crew was fantastic! Which the seats had a small TV.

also wi-fi never worked attendant said satellite coverage is spotty over water ..... but we were over land!

They attended to my needs as I couldn't walk and they provided a wheelchair for me.q

This time my flight was smooth and uneventful. They started boarding even earlier than it was scheduled. I was pleasantly surprised. Thank you!

Boarding was a mess - the agent basically called every group in rapid succession, so there was no organization at all. The economy seats are a joke, and main cabin extra seats were sold out when I purchased my flight. As such, I was locked in the same position for four hours. Being 6’6”, it was impossible to get my bag out from under the seat in front of me, and I couldn’t have used my laptop even if my bag were accessible due to the minuscule seat pitch. Also the wifi was broken. American is a joke - can’t wait until they merge with Spirit.

Cons: "Just seemed chaotic. Plane super late departing. Baggage pick up was a nightmare."

Everything you need to know for your flight from Myrtle Beach to San Diego

Information on your arrival and departure airports