$253 Find Cheap Flights from Panama City to Mexico City Federal District

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Mexico City Federal District departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City Federal District

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City Federal District, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City Federal District, as well as popular online travel agencies
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Flight Deals

Book Cheap Panama City to Mexico City Federal District Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Mexico City Federal District that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Mexico City Federal District

Sat, Mar 28 - Tue, Mar 31
Delta Logo
11:15 am - 7:50 pmECP-MEX
9h 35m1 stop
Delta Logo
3:45 pm - 8:20 amMEX-ECP
15h 35m1 stop
$560Delta
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Sat, Mar 28 - Tue, Mar 31
Aeromexico Logo
9:23 am - 7:50 pmECP-MEX
11h 27m1 stop
Aeromexico Logo
9:00 am - 4:37 pmMEX-ECP
6h 37m1 stop
$561Aeromexico
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Wed, Nov 12 - Wed, Nov 19
United Airlines Logo
5:00 pm - 12:10 amECP-MEX
7h 10m1 stop
United Airlines Logo
7:50 am - 1:57 pmMEX-ECP
6h 07m1 stop
$714United Airlines
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Wed, Nov 12 - Wed, Nov 19
American Airlines Logo
8:21 am - 9:15 pmECP-MEX
12h 54m2 stops
American Airlines Logo
6:00 am - 12:41 pmMEX-ECP
6h 41m1 stop
$718American Airlines
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Sat, Mar 28 - Tue, Mar 31
Delta Logo
9:23 am - 2:15 pmECP-MEX
5h 52m1 stop
Delta Logo
9:55 am - 10:42 pmMEX-ECP
11h 47m2 stops
$739Delta
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Sat, Mar 28 - Tue, Mar 31
Aeromexico Logo
1:30 pm - 7:50 pmECP-MEX
7h 20m1 stop
Aeromexico Logo
9:55 am - 6:58 pmMEX-ECP
8h 03m2 stops
$740Aeromexico
Find Deal
Sat, Mar 28 - Tue, Mar 31
Delta Logo
6:00 am - 4:35 pmECP-MEX
11h 35m2 stops
Delta Logo
9:55 am - 10:42 pmMEX-ECP
11h 47m2 stops
$744Delta
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Mon, Dec 22 - Thu, Dec 25
American Airlines Logo
10:26 am - 12:10 amECP-MEX
13h 44m2 stops
American Airlines Logo
8:00 am - 6:55 pmMEX-ECP
10h 55m1 stop
$883American Airlines
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Wed, Nov 12 - Tue, Nov 18
WestJet Logo
6:00 am - 3:15 pmECP-MEX
33h 15m2 stops
WestJet Logo
1:15 am - 8:35 amMEX-ECP
31h 20m2 stops
$2,058WestJet
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Mon, Dec 22 - Wed, Dec 24
WestJet Logo
4:04 pm - 3:35 pmECP-MEX
23h 31m2 stops
WestJet Logo
1:55 am - 6:15 pmMEX-ECP
16h 20m2 stops
$2,704WestJet
Find Deal
Booking Insights

KAYAK's insights & trends for Panama City to Mexico City Federal District flights

Get data-powered insights and trends into flights from Panama City to Mexico City Federal District to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Panama City to Mexico City Federal District?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Mexico City Federal District, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Mexico City Federal District is September, when tickets cost $534 (return) on average. On the other hand, the most expensive months are December and October, when the average cost of round-trip tickets is $1,034 and $1,013 respectively.

Good to know

Low seasonFebruary
Cheapest flight$253
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Panama City to Mexico City

FAQs - booking Mexico City Federal District flights

  • How does KAYAK find such low prices on flights from Panama City to Mexico City Federal District?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Mexico City Federal District.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Mexico City Federal District?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Mexico City Federal District is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Mexico City Federal District?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Mexico City Federal District with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Mexico City Federal District?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Mexico City Federal District up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Panama City to Mexico City Federal District

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Mexico City Federal District. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Mexico City Federal District? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8001 reviews
8.2Boarding
8.5Crew
7.9Comfort
7.9Entertainment
7.3Food
Airline reviews

Non stop on long haul is the way to go. Great experience

10.0 ExcellentEric, Oct 2025MCO - ATL
Read more Delta reviews

Non stop on long haul is the way to go. Great experience

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Passengers need to check in big baggage instead of bringing on the plane. That cause inconvenience for everyone. Otherwise flight was good.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Quick check in. Everything went smooth. I don't know what can be done about airline food.

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Overpriced tickets and attitudes to pay for such service. So bummed.

Flight was an hour late, who knows why. It was OK, nothing outstanding.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

The worst landing I have ever had on a domestic flight. Thought we would lose the landing gear on landing in Newark. Then we spent 40 minutes trying to position the plane in the right place to be able to get the jet way to the plane. The plane arrived stopped. The announcer was that we were there. Everybody got up, then we were told to sit back down because they had to have us towed to a different position. We got towed and then everyone stood up and they told us we were in the wrong position to sit back down again, and then we got towed to a different position This did not happen immediately. It was 30 minutes while we wandered around a small section of the tarmac in Newark close to the gate, but apparently not close enough. Horrifying experience The CAB should be investigating that flight

Boarding was organized. Plane seats comfortable and service was attentive. Food options were good.

We had to deboard 2 times due to maintenance issues. They changed the plane, and then we got deviated to LAX due to maibtenance issues on the other plane, had to sleep at LAX and los a full day.

It is clear that someone knew, and competent, is in charge of food at United Airlines at least for the international flights. I was flying in coach, but the choices of the dinner were excellent. Tasty, and appropriate size. I had the beef, which was a little bit like a shepherds pie, and it was good. Nothing comparable has been served on a United flight in years. It will not be confused with three star food, but it is very good for airline food. Even better was the breakfast choice between a cinnamon roll and a breakfast sandwich. I chose the breakfast sandwich which was absolutely delicious and which I would happily order again at my local Starbucks or Panera. It is clear that someone knew indifferent is in charge of the food and it’s about time.

Flight attendant in first class gave poor service (like he didn't want to be there) and food was awful. We sat waiting for gate upon arrival over 45 mins.

Staff was rude. Didn’t give water for 2 hours. Worst service

This is for UA2274 from Houston to Sacramento. The flight was delayed arriving due to mechanical issues so we left about 3 hours later than scheduled. When boarding the plane the temperature inside was excessive - likely close to 100. Pilot apologized and said it was going to improve at altitude, which it did. But before that I honestly thought there might have been more delays removing passengers made ill from the heat. We were delayed leaving due to another mechanical issue. There was not water on the plane due to a panel that was not secured. They did that quickly, but the combination of mechanical issues was rather disturbing and did not reflect well on United.

Staff members were not helpful they ignored all calls for an attendant.

Terrible. Delayed 7 hours, and cancelled the flight, leaving me stranded and out of pocket $500 for an alternative last minute flight

Everything you need to know for your flight from Panama City to Mexico City Federal District

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