ECP - MEX

$326 Find Cheap Flights from Panama City to Mexico City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Mexico City departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$550
Overall average: $613
American Airlines
Wed 4/29Fri 5/8
ECP - MEX • 1 stop
Cheapest one-way
$326
Delta
Fri 1/9
ECP - MEX • 2 stops
When to travel
September
Cheapest • 16% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Mexico City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Mexico City (ECP-MEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Mexico City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Mexico City

Wed, Apr 29 - Fri, May 8
American Airlines Logo
6:55 am - 11:49 am
ECP
-
MEX
5h 54m1 stop
American Airlines Logo
5:00 am - 2:08 pm
MEX
-
ECP
8h 08m1 stop
$550American Airlines
Wed, Apr 29 - Fri, May 8
American Airlines Logo
6:55 am - 7:15 pm
ECP
-
MEX
13h 20m2 stops
American Airlines Logo
7:00 am - 2:08 pm
MEX
-
ECP
6h 08m1 stop
$555American Airlines
Sun, May 3 - Wed, May 13
Delta Logo
6:00 am - 6:21 pm
ECP
-
MEX
13h 21m1 stop
Delta Logo
3:15 pm - 10:46 pm
MEX
-
ECP
6h 31m1 stop
$567Delta
Sun, May 3 - Tue, May 12
Delta Logo
6:00 am - 6:21 pm
ECP
-
MEX
13h 21m1 stop
Delta Logo
9:00 am - 10:46 pm
MEX
-
ECP
12h 46m2 stops
$572Delta
Sun, Jan 18 - Sun, Jan 25
United Airlines Logo
6:30 am - 4:45 pm
ECP
-
MEX
10h 15m1 stop
United Airlines Logo
12:25 pm - 9:59 pm
MEX
-
ECP
9h 34m1 stop
$590United Airlines
Sat, Apr 4 - Sun, Apr 12
Delta Logo
6:00 am - 3:30 pm
ECP
-
MEX
10h 30m2 stops
Delta Logo
8:40 am - 11:02 pm
MEX
-
ECP
13h 22m2 stops
$595Delta
Thu, Jan 15 - Mon, Jan 19
Delta Logo
6:00 am - 12:55 pm
ECP
-
MEX
6h 55m1 stop
Delta Logo
8:35 am - 7:50 pm
MEX
-
ECP
11h 15m2 stops
$620Delta
Sun, May 3 - Wed, May 13
Delta Logo
7:45 am - 5:55 pm
ECP
-
MEX
11h 10m2 stops
Delta Logo
9:00 am - 10:46 pm
MEX
-
ECP
12h 46m2 stops
$637Delta
Sat, Apr 4 - Sun, Apr 12
American Airlines Logo
12:40 pm - 6:35 pm
ECP
-
MEX
6h 55m1 stop
American Airlines Logo
7:00 am - 2:08 pm
MEX
-
ECP
6h 08m1 stop
$713American Airlines
Sun, Jan 18 - Thu, Jan 22
Aeromexico Logo
10:01 am - 8:50 pm
ECP
-
MEX
10h 49m1 stop
Aeromexico Logo
9:10 am - 10:40 pm
MEX
-
ECP
13h 30m2 stops
$730Aeromexico
Booking Insights

KAYAK's insights & trends for Panama City to Mexico City flights

Get data-powered insights and trends into flights from Panama City to Mexico City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Panama City to Mexico City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Mexico City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Mexico City is September, where tickets cost $534 (return) on average. On the other hand, the most expensive months are October and January, where the average cost of round-trip tickets is $1,013 and $721 respectively.

Good to know

Low seasonOctober
Cheapest flight$326
Best time to beat the crowds but there is an average 59% increase in price.
Most popular time to fly with an average 7% increase in price.
Flight from Panama City to Mexico City

When to book flights from Panama City to Mexico City

Are your dates flexible? Find out the best times to travel from Panama City to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Mexico City

  • What is the cheapest flight from Panama City to Mexico City?

    In the last 3 days, the lowest price for a flight from Panama City to Mexico City was $326 for a one-way ticket and $550 for a round-trip.

  • Do I need a passport to fly between Panama City and Mexico City?

    Yes

  • Which aircraft models fly most regularly from Panama City to Mexico City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to Mexico City?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Panama City and Mexico City, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Panama City to Mexico City, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to Mexico City are Delta and United Airlines. With an average price for the route of $577 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $601 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to Mexico City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Mexico City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Mexico City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Mexico City from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Mexico City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Mexico City with an airline and back to Panama City with another airline. Booking your flights between Panama City and MEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Mexico City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Mexico City from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Panama City to Mexico City

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Mexico City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Mexico City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8009 reviews
7.9Entertainment
8.1Boarding
7.9Comfort
7.3Food
8.5Crew
Airline reviews

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

4.0 OkayCarl, Dec 2025
FLL - LGA
Read more Delta reviews

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Non stop on long haul is the way to go. Great experience

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Passengers need to check in big baggage instead of bringing on the plane. That cause inconvenience for everyone. Otherwise flight was good.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Quick check in. Everything went smooth. I don't know what can be done about airline food.

Flight team stood out for perzonal attention, kindness at bright cheery attitudes at 8am. Very helpful.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

The worst landing I have ever had on a domestic flight. Thought we would lose the landing gear on landing in Newark. Then we spent 40 minutes trying to position the plane in the right place to be able to get the jet way to the plane. The plane arrived stopped. The announcer was that we were there. Everybody got up, then we were told to sit back down because they had to have us towed to a different position. We got towed and then everyone stood up and they told us we were in the wrong position to sit back down again, and then we got towed to a different position This did not happen immediately. It was 30 minutes while we wandered around a small section of the tarmac in Newark close to the gate, but apparently not close enough. Horrifying experience The CAB should be investigating that flight

Boarding was organized. Plane seats comfortable and service was attentive. Food options were good.

We had to deboard 2 times due to maintenance issues. They changed the plane, and then we got deviated to LAX due to maibtenance issues on the other plane, had to sleep at LAX and los a full day.

It is clear that someone knew, and competent, is in charge of food at United Airlines at least for the international flights. I was flying in coach, but the choices of the dinner were excellent. Tasty, and appropriate size. I had the beef, which was a little bit like a shepherds pie, and it was good. Nothing comparable has been served on a United flight in years. It will not be confused with three star food, but it is very good for airline food. Even better was the breakfast choice between a cinnamon roll and a breakfast sandwich. I chose the breakfast sandwich which was absolutely delicious and which I would happily order again at my local Starbucks or Panera. It is clear that someone knew indifferent is in charge of the food and it’s about time.

Flight attendant in first class gave poor service (like he didn't want to be there) and food was awful. We sat waiting for gate upon arrival over 45 mins.

Staff was rude. Didn’t give water for 2 hours. Worst service

This is for UA2274 from Houston to Sacramento. The flight was delayed arriving due to mechanical issues so we left about 3 hours later than scheduled. When boarding the plane the temperature inside was excessive - likely close to 100. Pilot apologized and said it was going to improve at altitude, which it did. But before that I honestly thought there might have been more delays removing passengers made ill from the heat. We were delayed leaving due to another mechanical issue. There was not water on the plane due to a panel that was not secured. They did that quickly, but the combination of mechanical issues was rather disturbing and did not reflect well on United.

Everything you need to know for your flight from Panama City to Mexico City

Information on your arrival and departure airports