ECP - MEX

$578 Find Cheap Flights from Panama City to Mexico City

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Mexico City departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$578
Typical prices: $538-$564
Aeromexico
Mon 8/31Thu 9/3
ECP - MEX • 1 stop
Top airlines
Aeromexico
Cheapest • from $578 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Panama City and Mexico City. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Atlanta (ATL)
Cheapest • Avg $529 (round-trip)
Houston (IAH)
Shortest trip • 5h 34m (one-way)
Insights
Insights
Insights
Insights
When to travel
September
Cheapest • 15% price drop
February
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Mexico City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Mexico City (ECP-MEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Mexico City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Mexico City

Mon, Aug 31 - Thu, Sep 3
Aeromexico Logo
7:45 am - 9:15 pm
ECP
-
MEX
14h 30m
1 stop
Aeromexico Logo
7:05 am - 7:37 pm
MEX
-
ECP
11h 32m
1 stop
$578Aeromexico
Mon, Aug 31 - Thu, Sep 3
Aeromexico Logo
7:45 am - 9:15 pm
ECP
-
MEX
14h 30m
1 stop
Aeromexico Logo
8:40 am - 5:51 pm
MEX
-
ECP
8h 11m
1 stop
$580Aeromexico
Wed, Apr 29 - Fri, May 8
American Airlines Logo
7:00 am - 8:45 pm
ECP
-
MEX
14h 45m
1 stop
American Airlines Logo
11:20 am - 9:58 pm
MEX
-
ECP
9h 38m
1 stop
$586American Airlines
Wed, Apr 29 - Fri, May 8
American Airlines Logo
7:21 am - 10:20 pm
ECP
-
MEX
15h 59m
2 stops
American Airlines Logo
10:55 am - 11:46 pm
MEX
-
ECP
11h 51m
2 stops
$591American Airlines
Mon, Aug 31 - Thu, Sep 3
Aeromexico Logo
7:45 am - 9:15 pm
ECP
-
MEX
14h 30m
1 stop
Aeromexico Logo
8:40 am - 10:46 pm
MEX
-
ECP
13h 06m
1 stop
$600Aeromexico
Sun, May 3 - Tue, May 12
Delta Logo
5:49 am - 1:55 pm
ECP
-
MEX
9h 06m
1 stop
Delta Logo
11:25 am - 11:01 pm
MEX
-
ECP
10h 36m
1 stop
$604Delta
Wed, Apr 29 - Fri, May 8
American Airlines Logo
7:00 am - 6:32 pm
ECP
-
MEX
12h 32m
1 stop
American Airlines Logo
7:00 am - 9:58 pm
MEX
-
ECP
13h 58m
1 stop
$606American Airlines
Sun, May 3 - Tue, May 12
Delta Logo
5:49 am - 1:55 pm
ECP
-
MEX
9h 06m
1 stop
Delta Logo
8:30 am - 11:01 pm
MEX
-
ECP
13h 31m
2 stops
$609Delta
Wed, Apr 29 - Fri, May 8
American Airlines Logo
7:00 am - 8:45 pm
ECP
-
MEX
14h 45m
1 stop
American Airlines Logo
5:35 am - 11:46 pm
MEX
-
ECP
17h 11m
2 stops
$611American Airlines
Sun, May 3 - Tue, May 12
Delta Logo
5:49 am - 1:55 pm
ECP
-
MEX
9h 06m
1 stop
Delta Logo
7:05 am - 4:30 pm
MEX
-
ECP
8h 25m
1 stop
$626Delta
Booking Insights

KAYAK's insights & trends for Panama City to Mexico City flights

Get data-powered insights and trends into flights from Panama City to Mexico City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City, Florida to Mexico City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City, Florida to Mexico City departing in August.

What is the cheapest month to fly from Panama City to Mexico City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Mexico City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Mexico City is September, where tickets cost $534 (return) on average. On the other hand, the most expensive months are October and June, where the average cost of round-trip tickets is $1,013 and $695 respectively.

Good to know

Low seasonOctober
Cheapest flight$578
Best time to beat the crowds but there is an average 61% increase in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Panama City to Mexico City

When to book flights from Panama City to Mexico City

Are your dates flexible? Find out the best times to travel from Panama City to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Mexico City

  • What is the cheapest flight from Panama City to Mexico City?

    In the last 3 days, the lowest price for a flight from Panama City to Mexico City was $578 for a round-trip ticket.

  • Do I need a passport to fly between Panama City and Mexico City?

    Yes

  • Which aircraft models fly most regularly from Panama City to Mexico City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to Mexico City?

    Star Alliance, and SkyTeam are the airline alliances operating flights between Panama City and Mexico City, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Panama City to Mexico City, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to Mexico City are Delta and United Airlines. With an average price for the route of $572 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $601 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to Mexico City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Mexico City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Mexico City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Mexico City from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Mexico City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Mexico City with an airline and back to Panama City with another airline. Booking your flights between Panama City and MEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Mexico City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Mexico City from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Panama City to Mexico City

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Mexico City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Mexico City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8248 reviews
8.5Crew
7.2Food
8.1Boarding
7.9Comfort
7.8Entertainment
Airline reviews

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

10.0 ExcellentBob, Feb 2026
FLL - MSP
Read more Delta reviews

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

This was my first time flying Delta ever and I had a great experience!

Excellent!!! Aeromexico is a great airline. What was not that good is the service provided by Kayak. It is never clear and not easy to manage.

The flight was great as well as the airline staff

Comfort seating was on the tight side. Maybe it was a smaller plane(?)

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Connection through Atlanta was difficult. Mechanical issue on plane caused a two hour delay. New gate was a mile away.

No WiFi. Comfort plus should have alcohol provided, crew only offered water or tea. Who the heck wants tea?

Plane outlets in my row not working to charge phone. Staff response was, well it should be. Plug into seed for volume not working well. Had to find the sweet spot for plug in or it would shut off and on.

Everything was absolutely wonderful from check in to baggage claim. Staff was very professional and sweet. Will definitely recommend United to family and friends.

Very turbulent trip made it pretty bearable, plus the lack of refreshments served and the lack of any air conditioning before takeoff which took an hour or more.

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

They charged a fee for 1st bag checked. Others in same party were free.

Flight team stood out for perzonal attention, kindness at bright cheery attitudes at 8am. Very helpful.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

The worst landing I have ever had on a domestic flight. Thought we would lose the landing gear on landing in Newark. Then we spent 40 minutes trying to position the plane in the right place to be able to get the jet way to the plane. The plane arrived stopped. The announcer was that we were there. Everybody got up, then we were told to sit back down because they had to have us towed to a different position. We got towed and then everyone stood up and they told us we were in the wrong position to sit back down again, and then we got towed to a different position This did not happen immediately. It was 30 minutes while we wandered around a small section of the tarmac in Newark close to the gate, but apparently not close enough. Horrifying experience The CAB should be investigating that flight

Boarding was organized. Plane seats comfortable and service was attentive. Food options were good.

We had to deboard 2 times due to maintenance issues. They changed the plane, and then we got deviated to LAX due to maibtenance issues on the other plane, had to sleep at LAX and los a full day.

Everything you need to know for your flight from Panama City to Mexico City

Information on your arrival and departure airports