ECP - MEX

$439 Find Cheap Flights from Panama City to Mexico City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Mexico City departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$629
Typical prices: $720-$663
Delta
Thu 6/11Thu 6/18
ECP - MEX • 1 stop
Cheapest one-way
$398
American Airlines
Tue 5/5
ECP - MEX • 2 stops
Top airlines
Delta
Cheapest • from $629 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Panama City and Mexico City. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Atlanta (ATL)
Cheapest • Avg $595 (round-trip)
Houston (IAH)
Shortest trip • 5h 47m (one-way)
Insights
Insights
Insights
Insights
When to travel
April
Cheapest • 100% price drop
February
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Mexico City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Mexico City (ECP-MEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Mexico City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Mexico City

Thu, Jun 11 - Thu, Jun 18
Delta Logo
2:46 pm - 9:50 pm
ECP
-
MEX
8h 04m
1 stop
Delta Logo
10:35 am - 11:44 pm
MEX
-
ECP
12h 09m
2 stops
$629Delta
Fri, Jun 5 - Tue, Jun 9
Aeromexico Logo
6:00 am - 4:05 pm
ECP
-
MEX
11h 05m
2 stops
Aeromexico Logo
11:10 am - 11:44 pm
MEX
-
ECP
11h 34m
1 stop
$644Aeromexico
Sat, Jul 11 - Mon, Jul 20
Delta Logo
9:22 am - 9:35 pm
ECP
-
MEX
13h 13m
2 stops
Delta Logo
8:50 am - 11:37 pm
MEX
-
ECP
13h 47m
2 stops
$649Delta
Sat, May 23 - Mon, May 25
United Airlines Logo
5:05 pm - 11:10 pm
ECP
-
MEX
7h 05m
1 stop
United Airlines Logo
4:40 am - 4:23 pm
MEX
-
ECP
10h 43m
1 stop
$697United Airlines
Sat, Jun 13 - Sat, Jun 20
Delta Logo
7:41 am - 5:50 pm
ECP
-
MEX
11h 09m
2 stops
Delta Logo
8:45 am - 11:07 pm
MEX
-
ECP
13h 22m
2 stops
$714Delta
Thu, Jun 11 - Thu, Jun 18
United Airlines Logo
6:30 am - 10:45 am
ECP
-
MEX
5h 15m
1 stop
United Airlines Logo
4:40 am - 1:51 pm
MEX
-
ECP
8h 11m
1 stop
$717United Airlines
Sat, Jul 11 - Mon, Jul 20
Delta Logo
9:22 am - 9:35 pm
ECP
-
MEX
13h 13m
2 stops
Delta Logo
8:50 am - 8:46 pm
MEX
-
ECP
10h 56m
2 stops
$734Delta
Sat, May 23 - Mon, May 25
American Airlines Logo
7:05 am - 8:49 pm
ECP
-
MEX
14h 44m
2 stops
American Airlines Logo
1:05 pm - 10:36 pm
MEX
-
ECP
8h 31m
1 stop
$769American Airlines
Sat, Jul 11 - Mon, Jul 20
Delta Logo
7:46 am - 7:00 pm
ECP
-
MEX
12h 14m
1 stop
Delta Logo
8:50 am - 11:37 pm
MEX
-
ECP
13h 47m
2 stops
$774Delta
Sat, Jul 11 - Mon, Jul 20
Delta Logo
7:50 am - 7:00 pm
ECP
-
MEX
12h 10m
1 stop
Delta Logo
8:50 am - 11:37 pm
MEX
-
ECP
13h 47m
2 stops
$779Delta
Booking Insights

KAYAK's insights & trends for Panama City to Mexico City flights

Get data-powered insights and trends into flights from Panama City to Mexico City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Panama City to Mexico City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Mexico City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Mexico City is April, where tickets cost $0 (return) on average. On the other hand, the most expensive months are October and June, where the average cost of round-trip tickets is $1,013 and $695 respectively.

Find deals

Good to know

Low seasonSeptember
Cheapest flight$398
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly and prices are also 12% lower on average.
Flight from Panama City to Mexico City

When to book flights from Panama City to Mexico City

Are your dates flexible? Find out the best times to travel from Panama City to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Mexico City

  • What is the cheapest flight from Panama City to Mexico City?

    In the last 3 days, the lowest price for a flight from Panama City to Mexico City was $398 for a one-way ticket and $629 for a round-trip.

  • Do I need a passport to fly between Panama City and Mexico City?

    Yes

  • Which aircraft models fly most regularly from Panama City to Mexico City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to Mexico City?

    SkyTeam is the only airline alliance operating flights between Panama City and Mexico City.

  • How does KAYAK find such low prices on flights from Panama City to Mexico City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Mexico City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Mexico City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Mexico City from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Mexico City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Mexico City with an airline and back to Panama City with another airline. Booking your flights between Panama City and MEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Mexico City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Mexico City from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to Mexico City

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Mexico City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Mexico City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8464 reviews
8.5Crew
7.2Food
7.9Comfort
7.8Entertainment
8.1Boarding
Airline reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

6.0 GoodSilvestre, Apr 2026
MCO - GRU
Read more Delta reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

Landed without a gate ready. Plane is extremely old and dirty.

All the amenities was wonderful, if they could keep their prices that low. I'd fly with them all the time.

The WiFi was horrific. I fly delta often and love their (usually reliable and free) WiFi. On this flight it was intermittent and when it did connect was extremely slow. I couldn’t get any work done while I was on the flight which was extremely frustrating. I was also in the exit row seat where there is now immediate seat in front of you, so while the leg room was nice, I couldn’t even watch the TV when the internet wasn’t working. Finally, for the last 20 mins of the flight, the announcement indicator came on the TV screens and took them over, even though no announcement was being made. Really disappointed.

Crew was great. Near on time departure and early arrival. Snacks are always meh. Not a fan of the "pay for everything including miles " proposal unless base flight rate going to be 100 bucks.

On the return flight, flight attendant Britt went out of her way to inform passengers that several of us had tight connections.

Too many people are taking up space in the overhead bins with their extra piece of luggage. Since they cannot fit their backpacks or extra luggage piece under the seat in front of them, they store it in the overheads and thus taking up room for other passengers. It wasn’t only one or two persons; more like 12 or 13 passengers.

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

Everything you need to know for your flight from Panama City to Mexico City

Information on your arrival and departure airports

Panama City (ECP)
Mexico City (MEX)