ECP - MEX

$473 Find Cheap Flights from Panama City to Mexico City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Mexico City departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Mexico City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Mexico City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$593
Typical prices: $540-$630
American Airlines
Wed 4/29Fri 5/8
ECP - MEX • 1 stop
Cheapest one-way
$473
American Airlines
Fri 3/6
ECP - MEX • 1 stop
Top airlines
American Airlines
Cheapest • from $593 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
September
Cheapest • 15% price drop
February
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Mexico City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Mexico City (ECP-MEX)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Mexico City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Mexico City

Wed, Apr 29 - Fri, May 8
American Airlines Logo
12:33 pm - 8:45 pm
ECP
-
MEX
9h 12m
1 stop
American Airlines Logo
12:35 pm - 11:46 pm
MEX
-
ECP
10h 11m
1 stop
$593American Airlines
Wed, Apr 29 - Fri, May 8
American Airlines Logo
7:21 am - 10:20 pm
ECP
-
MEX
15h 59m
2 stops
American Airlines Logo
5:15 pm - 10:03 am
MEX
-
ECP
15h 48m
2 stops
$597American Airlines
Fri, Jul 17 - Tue, Jul 21
Delta Logo
7:45 am - 3:30 pm
ECP
-
MEX
8h 45m
2 stops
Delta Logo
9:00 am - 10:46 pm
MEX
-
ECP
12h 46m
2 stops
$614Delta
Mon, Mar 16 - Mon, Mar 23
American Airlines Logo
4:34 pm - 11:45 am
ECP
-
MEX
20h 11m
1 stop
American Airlines Logo
12:45 pm - 9:36 am
MEX
-
ECP
19h 51m
1 stop
$630American Airlines
Mon, Mar 16 - Mon, Mar 23
American Airlines Logo
7:19 am - 10:22 pm
ECP
-
MEX
16h 03m
2 stops
American Airlines Logo
10:20 am - 9:36 am
MEX
-
ECP
22h 16m
1 stop
$646American Airlines
Sun, May 3 - Tue, May 12
Delta Logo
11:01 am - 10:00 pm
ECP
-
MEX
11h 59m
1 stop
Delta Logo
8:40 am - 6:56 pm
MEX
-
ECP
9h 16m
1 stop
$660Delta
Fri, Jul 17 - Tue, Jul 21
United Airlines Logo
9:00 am - 5:50 pm
ECP
-
MEX
9h 50m
1 stop
United Airlines Logo
2:15 pm - 9:59 pm
MEX
-
ECP
6h 44m
1 stop
$662United Airlines
Sun, May 3 - Tue, May 12
Delta Logo
5:49 am - 3:30 pm
ECP
-
MEX
10h 41m
2 stops
Delta Logo
9:05 am - 10:46 pm
MEX
-
ECP
12h 41m
2 stops
$664Delta
Fri, Feb 13 - Thu, Feb 19
American Airlines Logo
7:19 am - 9:55 pm
ECP
-
MEX
14h 36m
1 stop
American Airlines Logo
11:20 am - 10:06 am
MEX
-
ECP
22h 46m
1 stop
$666American Airlines
Fri, Feb 13 - Thu, Feb 19
American Airlines Logo
12:38 pm - 12:10 am
ECP
-
MEX
11h 32m
2 stops
American Airlines Logo
11:20 am - 10:06 am
MEX
-
ECP
22h 46m
1 stop
$671American Airlines
Booking Insights

KAYAK's insights & trends for Panama City to Mexico City flights

Get data-powered insights and trends into flights from Panama City to Mexico City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Panama City to Mexico City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Mexico City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Mexico City is September, where tickets cost $534 (return) on average. On the other hand, the most expensive months are October and January, where the average cost of round-trip tickets is $1,013 and $696 respectively.

Good to know

Low seasonOctober
Cheapest flight$473
Best time to beat the crowds but there is an average 60% increase in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Panama City to Mexico City

When to book flights from Panama City to Mexico City

Are your dates flexible? Find out the best times to travel from Panama City to Mexico City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to Mexico City

  • What is the cheapest flight from Panama City to Mexico City?

    In the last 3 days, the lowest price for a flight from Panama City to Mexico City was $473 for a one-way ticket and $593 for a round-trip.

  • Do I need a passport to fly between Panama City and Mexico City?

    Yes

  • Which aircraft models fly most regularly from Panama City to Mexico City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to Mexico City?

    Star Alliance, and SkyTeam are the airline alliances operating flights between Panama City and Mexico City, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Panama City to Mexico City, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to Mexico City are Delta and United Airlines. With an average price for the route of $572 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $609 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to Mexico City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Mexico City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Mexico City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Mexico City from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Mexico City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Mexico City with an airline and back to Panama City with another airline. Booking your flights between Panama City and MEX can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Mexico City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Mexico City from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Panama City to Mexico City

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Mexico City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Mexico City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8130 reviews
8.5Crew
8.1Boarding
7.9Comfort
7.8Entertainment
7.2Food
Airline reviews

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

10.0 ExcellentSteven, Jan 2026
FLL - CVG
Read more Delta reviews

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Connection through Atlanta was difficult. Mechanical issue on plane caused a two hour delay. New gate was a mile away.

No WiFi. Comfort plus should have alcohol provided, crew only offered water or tea. Who the heck wants tea?

I have diamond medallion status and usually we are in comfort plus . We were in main this time ( which was fine ) and my husband wanted wine . I have at least 10 vouchers for drinks that are good for this year and next! The attendant would not take the picture of the voucher as proof and never came back to check as She asked me to pull it up on delta Wi-Fi. Instead my husband just used his Amex to buy the wine . Disappointing!!!

Food is basically Sun Chips, cookies or Cheezits. I had an exit row seat so I had plenty of room. The crew was very nice and efficient. Pilot kept us informed. Pretty good flight.

The only thing nice I can say is the flight crew was really nice and apologetic about the situation. They shared as much information as they had and advised us on what we could do about missing connecting flights. The boarding process was so slow. The gate agent was working by herself and should have had someone working with her. It took almost an hour to board because she was trying to board a full flight of people and provide customer service to everyone who was flying standby and/or had questions. It was really chaotic. This didn't help the fact that we were delayed and folks were missing connections the longer it took.

The food is terrible. The staff is wonderful. Comfort is good.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

It was great with United overall except for two things. 1) It was a 5-hour flight and we were with kids, so we were asking for extra snacks. They were extremely reticent to dole them out even though there wasn't any meal and the kids were starting to hit their limit towards the end. 2) Baggage didn't arrive until 80 minutes after we landed.

Everything was absolutely wonderful from check in to baggage claim. Staff was very professional and sweet. Will definitely recommend United to family and friends.

Very turbulent trip made it pretty bearable, plus the lack of refreshments served and the lack of any air conditioning before takeoff which took an hour or more.

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

They charged a fee for 1st bag checked. Others in same party were free.

Flight team stood out for perzonal attention, kindness at bright cheery attitudes at 8am. Very helpful.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

Great smooth flight. Had a seating change, but that was an improvement. Thanks United Airways Crew.

The worst landing I have ever had on a domestic flight. Thought we would lose the landing gear on landing in Newark. Then we spent 40 minutes trying to position the plane in the right place to be able to get the jet way to the plane. The plane arrived stopped. The announcer was that we were there. Everybody got up, then we were told to sit back down because they had to have us towed to a different position. We got towed and then everyone stood up and they told us we were in the wrong position to sit back down again, and then we got towed to a different position This did not happen immediately. It was 30 minutes while we wandered around a small section of the tarmac in Newark close to the gate, but apparently not close enough. Horrifying experience The CAB should be investigating that flight

Boarding was organized. Plane seats comfortable and service was attentive. Food options were good.

Everything you need to know for your flight from Panama City to Mexico City

Information on your arrival and departure airports