$146 Find Cheap Flights from Panama City to San Francisco Bay Area - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to San Francisco Bay Area departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Panama City to San Francisco Bay Area

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Francisco
San Francisco1 stop$261
San Jose
San Jose1 stop$291
San Francisco
San Francisco1 stop$261
San Jose
San Jose1 stop$291

Book Cheap Panama City to San Francisco Bay Area Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to San Francisco Bay Area that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to San Francisco Bay Area

Sat, Sep 19 - Mon, Oct 26
Delta Logo
5:30 pm - 11:57 pm
ECP
-
SFO
8h 27m
1 stop
Delta Logo
11:45 pm - 8:14 am
SFO
-
ECP
6h 29m
1 stop
$261Delta
Sat, Sep 19 - Tue, Sep 22
Southwest Logo
11:45 am - 4:25 pm
ECP
-
SFO
6h 40m
1 stop
Southwest Logo
8:40 am - 8:30 pm
SFO
-
ECP
9h 50m
2 stops
$266Southwest
Sat, Sep 19 - Tue, Sep 22
Southwest Logo
11:45 am - 7:35 pm
ECP
-
SFO
9h 50m
2 stops
Southwest Logo
6:35 am - 6:45 pm
SFO
-
ECP
10h 10m
2 stops
$271Southwest
Thu, Sep 17 - Thu, Sep 24
Delta Logo
6:20 pm - 11:57 pm
ECP
-
SFO
7h 37m
1 stop
Delta Logo
11:35 pm - 8:16 am
SFO
-
ECP
6h 41m
1 stop
$277Delta
Thu, Aug 13 - Wed, Aug 19
Southwest Logo
4:25 pm - 8:40 pm
ECP
-
SJC
6h 15m
1 stop
Southwest Logo
7:40 am - 5:00 pm
SJC
-
ECP
7h 20m
1 stop
$291Southwest
Fri, Sep 18 - Tue, Sep 22
Delta Logo
4:35 pm - 11:57 pm
ECP
-
SFO
9h 22m
1 stop
Delta Logo
2:00 pm - 11:05 pm
SFO
-
ECP
7h 05m
1 stop
$296Delta
Thu, Aug 13 - Wed, Aug 19
Southwest Logo
5:10 am - 10:00 am
ECP
-
SJC
6h 50m
1 stop
Southwest Logo
8:00 am - 6:45 pm
SJC
-
ECP
8h 45m
2 stops
$296Southwest
Tue, Aug 25 - Tue, Sep 1
American Airlines Logo
3:15 pm - 10:18 pm
ECP
-
SFO
9h 03m
1 stop
American Airlines Logo
11:28 pm - 11:12 am
SFO
-
ECP
9h 44m
1 stop
$300American Airlines
Fri, Aug 14 - Wed, Aug 19
Southwest Logo
5:10 am - 10:00 am
ECP
-
SJC
6h 50m
1 stop
Southwest Logo
7:40 am - 5:00 pm
SJC
-
ECP
7h 20m
1 stop
$300Southwest
Sat, Sep 19 - Mon, Oct 26
Delta Logo
5:30 pm - 11:57 pm
ECP
-
SFO
8h 27m
1 stop
Delta Logo
11:45 pm - 8:14 am
SFO
-
ECP
6h 29m
1 stop
$301Delta
Booking Insights

KAYAK's insights & trends for Panama City to San Francisco Bay Area flights

Get data-powered insights and trends into flights from Panama City to San Francisco Bay Area to help you find the cheapest flights, the best time to fly and much more.

Can I save money by flying with a layover from Panama City to San Francisco Bay Area?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $445, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Panama City to San Francisco Bay Area?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to San Francisco Bay Area, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to San Francisco Bay Area is October, when tickets cost $227 (return) on average. On the other hand, the most expensive months are July and May, when the average cost of round-trip tickets is $436 and $415 respectively.

Good to know

Low seasonJanuary
Cheapest flight$146
Best time to beat the crowds with an average 25% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Panama City to San Jose

FAQs - booking San Francisco Bay Area flights

  • How does KAYAK find such low prices on flights from Panama City to San Francisco Bay Area?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to San Francisco Bay Area.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to San Francisco Bay Area?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to San Francisco Bay Area is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to San Francisco Bay Area?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to San Francisco Bay Area with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to San Francisco Bay Area?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to San Francisco Bay Area up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Panama City to San Francisco Bay Area

 
See real verified KAYAK customer reviews for airlines flying from Panama City to San Francisco Bay Area. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to San Francisco Bay Area? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4249 reviews
7.0Food
8.0Comfort
7.5Entertainment
8.6Crew
8.1Boarding
Airline reviews

The flight was late. The crew was rude. There was no food. Cramped and uncomfortable. Nothing about this flight was good.

2.0 MediocreIrene, Jun 2026
DEN - SFO
Read more Southwest reviews

The flight was late. The crew was rude. There was no food. Cramped and uncomfortable. Nothing about this flight was good.

It was just okay, no frills, basic transportation with no luxury. No screens on the seats, no water or drinks on a short flight. Full flight but at least it was on time.

The first time I flew in the extra legroom section. It was difficult to notice a difference. I had bad luck with my neighbors. The crew was okay. Southwest has reduced the live TV options.

No gluten free snacks. Seats felt worn or bare bones even though it was a new 737 MAX 8.

Plane was clean and comfortable. Flight attendants and gate staff were professional, friendly and efficient. Boarding and deplaning were orderly and efficient. All in all, the typical excellent Southwest experience.

Not having a five hour delay with little notice! The crew was very kind, though, and just as tired as we passengers were. The flight didn't depart until nearly 1 am...and no reason was ever given.

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

The Air hostess were very rude on my flight from Houston to Austin . Their regular communication itself felt a they are shouting at people.

Boarding was easy. The seats are small and fairly uncomfortable

Crew always seems to be unprofessional no matter what Southwest flight I fly

We never made it on this flight because we missed our connection due to o delayed flight from Jackson.

We got stuck on the tarmac taxiing after landing early so we didn’t get off the plane until an hour later than we thought we would

It was okay. We were delayed for weather reasons, but the pilots and the flight control staff figured a way around the storm and were able to get us to Los Angeles safely. Not all the staff members were polite, but the entertainment on the flight was good.

Crew was real good, flight was smooth and came in early.

Love me some Delta. One of the few airlines to recognize and support veterans. Easy boarding, flight was on time and arrived early and the flight attendants were excellent on this flight.

We sat on the runway for over an hour before departure. That was unwelcome.

Planes were clean, no water or snacks on either flight.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Worst service and meal in Delta First Class ever. I am really surprised as a loyal Delta flier. There was no welcoming or warmth from the crew toward us or our fellow travelers in the First Class cabin of the Airbus 321 Neo plane.

It was a short, comfortable flight. It did leave an hour late due to the pilot having to be replaced (family emergency) but that didn’t inconvenience myself & my friend. The situation was explained, eventually.

There was a piece of plastic baked into my buttermilk biscuit! I have a pictures. The flight attendants in first class were really apologetic, and tried to rectify the situation. I I am very appreciative that they were able to give me some packets of pretzels and gummy bears. I understand they don't personally handle the food until warming it up so I know it wasn't their fault. I don't know whether it was a newer aircraft, or different food packaging, but I was happy that when the food was being warmed up - it didn't smell like plastic. Jokes on me with finding plastic in my food.

The seats were uncomfortable, as if the cushions haven't been switched out in many years. I felt like I was on an old bus. The food was delicious. thank you. Onboard entertainment, very limited. Unless you like violent movies. Why in the world would you have such severely violent movies on a plane? if you don't want to see such things, you don't have a choice. Have you considered that when choosing entertainment? Good god. Why would you have the Godfather? Or black women being brutally beaten with a club? Why in the hell would you put that kind of material on a plane? As for Kayak: Why when I ordered Qantas, was the plane on United?

UA594 was delayed multiple times. I ended up getting picked up so I can make it in time for work 6AM on Monday, 7/6/2026

Excellent flight. On time. Great staff. Clean and crisp cabin.

Know that the movies that you are going to be offered are the oldest be rated movies they could possibly get. They may have one or two new movies that they keep advertising but when you’re flying 15 hours, there is nothing to see past the first new movie.

6 1/2 hours from Tampa to SFO on a Boeing 737. Cramped. No Service. No real food. One pass for coffee at the beginning and a second pass THREE hours later. And check-in in Tampa was nasty even by United standards. And I am at almost TWO million miles on United. It's a non-stop. But terrible service.

My flight was delayed a very short period of time but they did not hold my connecting flight to San Diego, also through United. So they closed the doors before we got off our plane. They would only have to help the door open for another five to ten minutes. So I missed a court deadline for a manditory mediation settlement conference for my client. I had to get an associate to be there in person and be on the phone with him relaying what he needs to do the entire time. The court was very upset with me and so was my client. United cannot be trusted.

Awful. Worst airline I have ever been on. Crew were among the rudest people I have ever dealt with. United staff members were rude and disrespectful. My flight was delayed, causing me to miss a connecting flight. I understand things happen, but when staff start lying about what actually happened, that is when I have an issue. Just be honest, really it isn’t that hard. I’m being very honest with this review and I don’t find this difficult what so ever. In fact, because of United Airlines, my Christmas holiday was off to a really rocky start. As someone who has traveled across the world, it has only been United that I have had a truly awful experience.

Boarding always seems a bit chaotic. Seat spacing could leave more for leg room.

I don’t like the music section but I believe it was a cost decision. I changed my flight last minute due to work issues and had to sit way in the back. The seats were way closer together than I would have preferred.

The flight attendant was very polite and attentive. The food was good.

Flight cancelled. Twice. And no communication. No gate agent. Went past boarding time and had to go and see email from AA. Airport communication was bad

It was so much better than expected, Ohare is not such a pleasant experience but American Airlines with the new, clean aeroplane and free Wi-Fi was outstanding and the crew so pleasant and helpful.

Flight: Started on time. Comfortable flight. Arrived on time. Crew: Very cordial and helpful. Drinks and snack was served with a smile. Overall enjoyed the trip. Regards, Hari Doss Chanchala Doss

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Plane felt so crowded and tightly packed. The chair itself was not comfortable.

2.5h delay due to unruly passenger in first class. Had to be removed from the flight. No food unless pre ordered. Didn't know we would need it because of delay.

Everything you need to know for your flight to San Francisco Bay Area

Information on your arrival and departure airports