PTY - SAN

$284 Find Cheap Flights from Panama City to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to San Diego departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to San Diego, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Expert advice
Booking Insights
Flight Deals

Cheap Flights from Panama City to San Diego (PTY-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to San Diego

Wed, Nov 5 - Mon, Nov 10
Copa Airlines Logo
1:15 pm - 5:03 pmPTY-SAN
6h 48mnonstop
Copa Airlines Logo
8:10 pm - 5:20 amSAN-PTY
6h 10mnonstop
$461Copa Airlines
Find Deal
Wed, Nov 5 - Mon, Nov 10
Delta Logo
3:21 pm - 11:14 pmPTY-SAN
10h 53m1 stop
Delta Logo
10:30 pm - 2:12 pmSAN-PTY
12h 42m1 stop
$466Delta
Find Deal
Fri, Oct 31 - Fri, Nov 7
United Airlines Logo
3:41 pm - 6:24 pmPTY-SAN
28h 43m1 stop
United Airlines Logo
5:55 pm - 6:49 pmSAN-PTY
21h 54m1 stop
$488United Airlines
Find Deal
Wed, Nov 5 - Mon, Nov 10
American Airlines Logo
2:49 pm - 9:55 amPTY-SAN
22h 06m2 stops
American Airlines Logo
2:55 pm - 1:49 pmSAN-PTY
19h 54m2 stops
$489American Airlines
Find Deal
Fri, Oct 31 - Fri, Nov 7
Copa Airlines Logo
1:15 pm - 5:57 pmPTY-SAN
6h 42mnonstop
Copa Airlines Logo
8:10 pm - 5:20 amSAN-PTY
6h 10mnonstop
$503Copa Airlines
Find Deal
Fri, Oct 31 - Fri, Nov 7
United Airlines Logo
3:41 pm - 10:41 amPTY-SAN
21h 00m2 stops
United Airlines Logo
6:47 pm - 7:38 pmSAN-PTY
21h 51m2 stops
$621United Airlines
Find Deal
Wed, Oct 1 - Sun, Oct 5
Copa Airlines Logo
1:15 pm - 5:57 pmPTY-SAN
6h 42mnonstop
Copa Airlines Logo
9:12 pm - 5:25 amSAN-PTY
6h 13mnonstop
$632Copa Airlines
Find Deal
Wed, Oct 1 - Sun, Oct 5
American Airlines Logo
1:45 pm - 9:58 pmPTY-SAN
10h 13m1 stop
American Airlines Logo
10:45 pm - 2:03 pmSAN-PTY
13h 18m1 stop
$659American Airlines
Find Deal
Thu, Oct 30 - Fri, Nov 7
Multiple Airlines Logo
2:55 am - 11:50 pmPTY-SAN
22h 55m3 stops
Multiple Airlines Logo
8:10 pm - 5:20 amSAN-PTY
6h 10mnonstop
$662Multiple Airlines
Find Deal
Thu, Oct 30 - Fri, Nov 7
Multiple Airlines Logo
2:55 am - 8:07 pmPTY-SAN
19h 12m2 stops
Multiple Airlines Logo
8:10 pm - 5:20 amSAN-PTY
6h 10mnonstop
$692Multiple Airlines
Find Deal

Everything you should know

Our travelers' advice
AI-generated summary based on content written by travel experts
For U.S.-bound flights, arrive early at PTY for security.
Use Route 992 bus for a budget-friendly ride from SAN.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Copa Airlines
Cheapest • from $461 (round-trip)
Copa Airlines
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
October
Cheapest • 28% price drop
October
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Nonstop flights
4 days a week
There are direct flights from Panama City to San Diego 4 days a week: Mon, Wed, Fri, Sun.
Direct flights
Direct flights
Direct flights
Direct flights
Cheapest round-trip
$461
Overall average: $506
Copa Airlines
Wed 11/5Mon 11/10
PTY - SAN • Non-stop
Cheapest one-way
$284
Typical prices: $366-421
Multiple Airlines
Thu 11/13
PTY - SAN • 3 stops
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Diego!
Expert advice

Expert advice for your flight from Panama City to San Diego

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airports
PTY

For U.S.-bound flights, arrive early at PTY for a secondary security screening at the gate.

Read more about PTYby Mark Chesnut
SAN

Use the Route 992 bus for a budget-friendly 15-minute ride from SAN to Downtown San Diego.

Read more about SANby Brandon Schultz
Our travel experts
Brandon Schultz

Brandon Schultz

Expert on SAN

Brandon Schultz

Brandon Schultz

Brandon Schultz is an award-winning food and travel writer based in New York City. His work has appeared in Forbes, AAA, Thrillist, Travel + Leisure, and The Daily Meal, among many others, and he is the author of 6 books, including 3 cookbooks.

Read more
Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut

Mark Chesnut

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more
Booking Insights

KAYAK's insights & trends for Panama City to San Diego flights

Get data-powered insights and trends into flights from Panama City to San Diego to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to San Diego?

The average price of all round-trip flights from Panama City to San Diego clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Panama City to San Diego, look for departures on Wednesdays and avoid leaving on a Thursday, as it's usually the priciest day. When flying back from San Diego, Wednesday is the cheapest day to fly and Friday is the most expensive.

What is the cheapest month to fly from Panama City to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to San Diego is October, where tickets cost $406 (return) on average. On the other hand, the most expensive months are January and February, where the average cost of round-trip tickets is $730 and $705 respectively.

Can I save money by flying with a layover from Panama City to San Diego?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $297, prices are generally cheapest when you fly direct.

Good to know

Low seasonMarch
Cheapest flight$284
Best time to beat the crowds but there is an average 7% increase in price.
Most popular time to fly and prices are also 29% lower on average.
Flight from Panama City to San Diego

When to book flights from Panama City to San Diego

Are your dates flexible? Find out the best times to travel from Panama City to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to San Diego

  • What is the cheapest flight from Panama City to San Diego?

    In the last 3 days, the lowest price for a flight from Panama City to San Diego was $284 for a one-way ticket and $461 for a round-trip.

  • Do I need a passport to fly between Panama City and San Diego?

    Yes

  • Which aircraft models fly most regularly from Panama City to San Diego?

    The Boeing 737 MAX 9 is the aircraft model that flies most regularly on the Panama City to San Diego flight route.

  • Which airline alliances offer flights from Panama City to San Diego?

    Star Alliance is the only airline alliance operating flights between Panama City and San Diego.

  • On which days can I fly direct from Panama City to San Diego?

    You can catch a nonstop flight from Panama City to San Diego on on Monday, Wednesday, Friday, and Sunday.

  • Which is the best airline for flights from Panama City to San Diego, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to San Diego are Copa Airlines and United Airlines. With an average price for the route of $443 and an overall rating of 7.6, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $600 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Panama City with another airline. Booking your flights between Panama City and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to San Diego

  • Looking for a cheap flight? 25% of our users found flights on this route for $435 or less one-way and $224 or less round-trip.

Prefer to fly direct from Panama City to San Diego?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to San Diego.
Find which airlines fly direct from Panama City Tocumen Intl Airport to San Diego Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to San Diego

Monday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

San Diego to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Panama City to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Panama City to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1533 reviews
7.8Boarding
8.1Crew
7.4Comfort
6.8Food
6.8Entertainment
Airline reviews

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

10.0 ExcellentNeil, Aug 2025PTY - BGI
Read more Copa Airlines reviews

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Great experience with a crew always thinking in the passenger

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

It was ok. However, the food was quite poor since I don't eat pasta.

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

The flight was comfortable with the exit row and great service

Plane was crowded and even when we hit altitude, the plane was hot, not enough air flow.

1. when we went to check in, our 2 first class seats had been CANCELED and the flight was sold out. This was done without our prior knowledge. It was all we could do to restore one first class seat for my wife and I flew economy. 2, Our flight home was scheduled to leave at 10:30 pm. Due to tsunami warnings, the roads were closed and our flight status was uncertain as to whether it would leave as scheduled. It was announced that it would now leave at 11:20 pm and the roads were now open since the tsunami had come and gone. We made a mad dash to the airport and checked in. Delays were announced at 12:30 pm, 1:30 am, 2:30 am and at 3:30 am it was canceled. Since this was a flight due to natural (tsunami) causes, there was no compensation. We were told to return at 1:00 pm the next day and our baggage would be kept on the plane since the same plane was going to leave at 1:00 pm. We had to return to our hotel for the rest of the night. The same plane did not leave at 1:00 pm and our baggage was gone! All in all, it was a miserable performance by UA. Information was hard to obtain and no one knew what was going on and what was going to happen. Hundreds of passengers slept on the floor, chairs, etc. No food and no water was made available to the passengers. It was a situation where UA could care less what was going on. As a one million mile flyer, I had not experienced anything like this before and it was hugely disappointing!

I found the staff to not be very attentive at all. When paying for Business Class you expect a certain type of service and that was not found. They were almost rude even

Ok. Get a different kosher caterer. The food was odd.

Our experience on United Airlines was extremely poor. The plane was extremely cold throughout our entire flight- which multiple people complained about- and we had to wait 2 hours to get a blanket which was too thin and barely helped warm us up. As well as this, none of the entertainment features were working so we had to sit through a roughly 10 hour flight with nothing to keep our attention, including the actual flight path screen. It was an extremely disappointing experience and I would hope that this gets fixed if we ever choose United Airlines again.

I really enjoyed flying with United airlines amazing experience , good customer service and great food

1.It will be better if sandwich is warm. 2.The food is too salty. 3.Breakfast needs some vegetables or fruits.

More racist flight attandants maybe because i sm an attracticted darkskin latino man but once again bad flight attamdants they ignored me the whole flight even the woman sitting next to me notice how rude they were towards me i really never want to fly united or american airlines they alawsys have the rudesslt and racist flight attandants

Boarded plane and then delayed 1.5 hours while on the plane

Everything you need to know for your flight from Panama City to San Diego

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.