PTY - SAN

$339 Find Cheap Flights from Panama City to San Diego - Compare and Save

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to San Diego departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$339
Typical prices: $406-$735
United Airlines
Fri 10/16Tue 10/27
PTY - SAN • 2 stops
Cheapest non-stop
$558
Typical prices: $576-$725
Copa Airlines
Fri 9/4Fri 10/2
PTY - SAN • Non-stop
Nonstop flights
Mon, Wed, Thu, Fri, Sun
You can fly direct with Copa Airlines. Average duration is 6h 35m
Direct flights
Direct flights
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Direct flights
Direct flights
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Top airlines
Cheapest • from $339 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
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Top layover airports
Cheapest • Avg $648 (round-trip)
Shortest trip • 10h 14m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 39% price drop
Most popular
Good to know
Good to know
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Good to know
Good to know
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Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to San Diego (PTY-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to San Diego

Fri, Oct 16 - Tue, Oct 27
United Airlines Logo
3:30 pm - 10:17 am-
20h 47m
United Airlines Logo
4:45 pm - 6:38 pm-
23h 53m
$339United Airlines
Fri, Oct 16 - Tue, Oct 27
United Airlines Logo
3:30 pm - 3:40 pm-
26h 10m
United Airlines Logo
6:26 pm - 1:45 pm-
17h 19m
$339United Airlines
Sun, Sep 6 - Sun, Sep 13
United Airlines Logo
3:30 pm - 9:05 am-
19h 35m
United Airlines Logo
5:00 pm - 6:37 pm-
23h 37m
$339United Airlines
Fri, Oct 16 - Tue, Oct 27
United Airlines Logo
3:30 pm - 1:17 pm-
23h 47m
United Airlines Logo
3:04 pm - 1:45 pm-
20h 41m
$339United Airlines
Sun, Sep 6 - Sun, Sep 13
Copa Airlines Logo
1:54 pm - 6:29 pm-
6h 35mnonstop
Copa Airlines Logo
10:00 pm - 6:17 am-
6h 17mnonstop
$558Copa Airlines
Fri, Sep 4 - Fri, Oct 2
Copa Airlines Logo
1:54 pm - 6:29 pm-
6h 35mnonstop
Copa Airlines Logo
10:00 pm - 6:13 am-
6h 13mnonstop
$558Copa Airlines
Wed, Sep 2 - Mon, Sep 7
Copa Airlines Logo
1:54 pm - 6:29 pm-
6h 35mnonstop
Copa Airlines Logo
10:00 pm - 6:17 am-
6h 17mnonstop
$558Copa Airlines
Wed, Oct 7 - Mon, Oct 12
American Airlines Logo
1:52 pm - 9:10 am-
21h 18m
American Airlines Logo
9:25 pm - 12:52 pm-
13h 27m
$577American Airlines
Wed, Oct 7 - Mon, Oct 12
American Airlines Logo
1:52 pm - 10:43 pm-
10h 51m
American Airlines Logo
9:25 pm - 12:52 pm-
13h 27m
$577American Airlines
Wed, Sep 2 - Mon, Sep 7
American Airlines Logo
1:39 pm - 10:49 pm-
11h 10m
American Airlines Logo
10:45 pm - 12:39 pm-
11h 54m
$582American Airlines
Booking Insights

KAYAK's insights & trends for Panama City to San Diego flights

Get data-powered insights and trends into flights from Panama City to San Diego to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to San Diego?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to San Diego departing in October.

Flight prices are below average for this route right now.

Flights to San Diego from Panama City usually cost between $624 and $714 in October.
The lowest price found in the past 5 days was $339 on United Airlines (Oct 16-Oct 27).

What’s the cheapest day of the week to fly from Panama City to San Diego?

The average price of all round-trip flights from Panama City to San Diego clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Panama City to San Diego, look for departures on Mondays and avoid leaving on a Tuesday, as it's usually the priciest day. When flying back from San Diego, Wednesday is the cheapest day to fly and Saturday is the most expensive.

What is the cheapest month to fly from Panama City to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to San Diego is November, where tickets cost $434 (return) on average. On the other hand, the most expensive months are June and April, where the average cost of round-trip tickets is $1,217 and $881 respectively.

Can I save money by flying with a layover from Panama City to San Diego?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $513, prices are generally cheapest when you fly direct.

Expert advice

Expert advice for your flight from Panama City to San Diego

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Brandon Schultz

Brandon Schultz

Expert on SAN

Brandon Schultz is an award-winning food and travel writer based in New York City. His work has appeared in Forbes, AAA, Thrillist, Travel + Leisure, and The Daily Meal, among many others, and he is the author of 6 books, including 3 cookbooks.

Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Good to know

Low season

June

Cheapest flight

$339
Best time to beat the crowds but there is an average 70% increase in price.
Most popular time to fly and prices are also 21% lower on average.
Flight from Panama City to San Diego

When to book flights from Panama City to San Diego

Are your dates flexible? Find out the best times to travel from Panama City to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to San Diego

  • How many flights are there between Panama City and San Diego per day?

    There is a maximum of 1 nonstop flight a day that takes off from Panama City and lands in San Diego, with an average flight time of 6h 35m. The most common departure time is 1:00 pm and most flights take off in the afternoon. Each week, there are 4 flights.

  • What is the cheapest flight from Panama City to San Diego?

    In the last 5 days, the lowest price for a flight from Panama City to San Diego was $360 for a one-way ticket and $339 for a round-trip.

  • Do I need a passport to fly between Panama City and San Diego?

    Yes

  • Which aircraft models fly most regularly from Panama City to San Diego?

    The Boeing 737 MAX 9 is the aircraft model that flies most regularly on the Panama City to San Diego flight route.

  • Which airline alliances offer flights from Panama City to San Diego?

    Star Alliance is the only airline alliance operating flights between Panama City and San Diego.

  • On which days can I fly direct from Panama City to San Diego?

    You can catch a nonstop flight from Panama City to San Diego on on Monday, Wednesday, Friday, and Sunday.

  • Which is the best airline for flights from Panama City to San Diego, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to San Diego are Copa Airlines and United Airlines. With an average price for the route of $707 and an overall rating of 7.6, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $722 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Panama City with another airline. Booking your flights between Panama City and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Panama City to San Diego?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to San Diego.
Find which airlines fly direct from Panama City Tocumen Intl Airport to San Diego Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to San Diego

Monday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

San Diego to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Panama City to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Panama City to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1565 reviews
6.8Entertainment
7.4Comfort
6.9Food
7.8Boarding
8.1Crew
Airline reviews

stood in line to check in luggage for nearly an hour. very poor service and not excusable

4.0 OkayAnonymous, Jun 2026
Read more Copa Airlines reviews

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Some of the Air hostesses are not that friendly. Need improvement

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

Horrible food. No wine or any other alcohol is served on the flight. Water is not served often and they refused when I asked for water in two cups. On the other hand, both going and coming back flights were on time.

it was great! Boarded on-time, reasonable leg room, pleasant staff, decent food. The only thing is we were directed to Terminal 2 when the gate was actually in Terminal 1. Smooth ride. Landed early. Got off plane easily and quickly.

Delayed 2 hours while stuck on the aircraft. If the luggage was properly loaded the first time we probably wouldn’t have been delayed at all

UA594 was delayed multiple times. I ended up getting picked up so I can make it in time for work 6AM on Monday, 7/6/2026

It was terrible. sat on airplane 2 hours then flight was canceled. made to pick up bags and go through Panama immagration to rebook another flight. worst experice ever at a airport.

Crew was tired as we all were. Pretty abrupt. Flight was delayed. Not as enjoyable as the other 3 legs we flew.

Horrific. They missed my connecting flight to San Diego. I didn’t get there until Monday at 9am when I had a mandatory court settlement conference scheduled at 6am since we had parties on the east coast. This caused many issues. All because United apparently forgot to hold the doors open until my flight landed that only had a 10 minute delay. This was the last flight to Southern California. So I couldn’t even rent a car to finish the trip. United cannot be trusted when traveling on specific days and times since weather didn’t have anything to do with the delays.

Was a pain having to leave the plane and reboard but glad the plane was fixed

Connecting flights were poor,especially in Naples.our Lufthansa air bus was a joke.way too small for that long of a flight.no room at all.couldn’t even get out of the seats to move around or go to the bathrooms.we thought we were getting an actual air bus,double decker.i will never fly that long in a plane like that again.kind of misleading to call it an air bus.we actually had more room on our buses that we used.

For a 22 minute flight all you expect is for it to be safe and comfortable

Lost connnection had to stayON in Chicago Was a mess

Booked economy through United - air canada treated it as standby and was almost refused boarding.

Everything you need to know for your flight from Panama City to San Diego

Information on your arrival and departure airports