PTY - SAN

$308 Find Cheap Flights from Panama City to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to San Diego departing on 4/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to San Diego, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$494
Overall average: $663
Copa Airlines
Wed 5/27Sun 5/31
PTY - SAN • Non-stop
Cheapest one-way
$359
Typical prices: $504-$582
Multiple Airlines
Mon 4/27
PTY - SAN • 2 stops
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
For U.S.-bound flights, arrive early at PTY for security.
Use Route 992 bus for a budget-friendly ride from SAN.
Expert advice
Expert advice
Expert advice
Expert advice
Nonstop flights
4 days a week
Mon, Wed, Fri, Sun
You can fly direct with Copa Airlines. Average duration is 6h 59m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top airlines
Copa Airlines
Cheapest • from $494 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Atlanta (ATL)
Cheapest • Avg $648 (round-trip)
Houston (IAH)
Shortest trip • 10h 05m (one-way)
Insights
Insights
Insights
Insights
When to travel
October
Cheapest • 28% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Diego!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to San Diego (PTY-SAN)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to San Diego

Wed, May 27 - Sun, May 31
Copa Airlines Logo
1:39 pm - 6:30 pm
PTY
-
SAN
6h 51mnonstop
Copa Airlines Logo
10:00 pm - 6:07 am
SAN
-
PTY
6h 07mnonstop
$494Copa Airlines
Fri, May 29 - Tue, Jun 2
GOL Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
GOL Logo
1:21 pm - 12:13 pm
SAN
-
PTY
20h 52m
2 stops
$515GOL
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 11:18 am
PTY
-
SAN
24h 04m
1 stop
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$518American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 11:18 am
PTY
-
SAN
24h 04m
1 stop
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$519American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 11:51 am
PTY
-
SAN
24h 37m
2 stops
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$521American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$522American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$523American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$524American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 11:51 am
PTY
-
SAN
24h 37m
2 stops
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$525American Airlines
Tue, May 26 - Sat, May 30
GOL Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
GOL Logo
1:21 pm - 12:13 pm
SAN
-
PTY
20h 52m
2 stops
$569GOL
Booking Insights

KAYAK's insights & trends for Panama City to San Diego flights

Get data-powered insights and trends into flights from Panama City to San Diego to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to San Diego?

The average price of all round-trip flights from Panama City to San Diego clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Panama City to San Diego, look for departures on Mondays and avoid leaving on a Friday, as it's usually the priciest day. When flying back from San Diego, Thursday is the cheapest day to fly and Saturday is the most expensive.

What is the cheapest month to fly from Panama City to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to San Diego is October, where tickets cost $394 (return) on average. On the other hand, the most expensive months are February and March, where the average cost of round-trip tickets is $722 and $710 respectively.

Can I save money by flying with a layover from Panama City to San Diego?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $573 on average.

Find deals
Expert advice

Expert advice for your flight from Panama City to San Diego

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Brandon Schultz

Brandon Schultz

Expert on SAN

Brandon Schultz is an award-winning food and travel writer based in New York City. His work has appeared in Forbes, AAA, Thrillist, Travel + Leisure, and The Daily Meal, among many others, and he is the author of 6 books, including 3 cookbooks.

Read more
Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more

Good to know

Low seasonApril
Cheapest flight$359
Best time to beat the crowds but there is an average 10% increase in price.
Most popular time to fly with an average 3% increase in price.
Flight from Panama City to San Diego

When to book flights from Panama City to San Diego

Are your dates flexible? Find out the best times to travel from Panama City to San Diego based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to San Diego

  • What is the cheapest flight from Panama City to San Diego?

    In the last 3 days, the lowest price for a flight from Panama City to San Diego was $308 for a one-way ticket and $494 for a round-trip.

  • Do I need a passport to fly between Panama City and San Diego?

    Yes

  • Which aircraft models fly most regularly from Panama City to San Diego?

    The Boeing 737 MAX 9 is the aircraft model that flies most regularly on the Panama City to San Diego flight route.

  • Which airline alliances offer flights from Panama City to San Diego?

    Star Alliance is the only airline alliance operating flights between Panama City and San Diego.

  • On which days can I fly direct from Panama City to San Diego?

    You can catch a nonstop flight from Panama City to San Diego on on Monday, Wednesday, Friday, and Sunday.

  • Which is the best airline for flights from Panama City to San Diego, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to San Diego are Copa Airlines and United Airlines. With an average price for the route of $494 and an overall rating of 7.5, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $679 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Panama City with another airline. Booking your flights between Panama City and SAN can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to San Diego

  • Looking for a cheap flight? 25% of our users found flights on this route for $748 or less one-way.

Prefer to fly direct from Panama City to San Diego?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to San Diego.
Find which airlines fly direct from Panama City Tocumen Intl Airport to San Diego Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to San Diego

Monday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

San Diego to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top airlines flying from Panama City to San Diego

 
See real verified KAYAK customer reviews for airlines flying from Panama City to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1572 reviews
6.8Food
6.8Entertainment
8.1Crew
7.8Boarding
7.4Comfort
Airline reviews

Do not book it’s a scam! They stole $1200 from me

2.0 MediocreTalicia, Mar 2026
PTY - RDU
Read more Copa Airlines reviews

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Some of the Air hostesses are not that friendly. Need improvement

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

The head flight attendant made the trip excellent. He was very accommodating.

The economy seats on the 777 was not as cramped as I had feared, but the food was terrible.

Terrible experience! delay 2 time and say i dont have ticket

It was amazing. I had several upgraded seats on my flight out. Everything went smooth with no delays.

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

Crew was tired as we all were. Pretty abrupt. Flight was delayed. Not as enjoyable as the other 3 legs we flew.

Flight attendants were friendly & good service, food sucks, seats uncomfortable, not many Asian movies or shows flying from Hong Kong

Flight attendants had a little attitude. Food tastes no good.

Overall we had a good experience during our flight from San Francisco to Houston.

it was a very short flight so my expectations were low.

Everything you need to know for your flight from Panama City to San Diego

Information on your arrival and departure airports

Panama City (PTY)
San Diego (SAN)