$369 Find Cheap Flights from Panama City to San Diego - Compare and Save

These are the earliest and latest flight times available from Panama City to San Diego:

• Earliest: departs at 1:45 pm and lands at 8:22 pm
• Latest: departs at 1:45 pm and lands at 8:22 pm.

The flight takes about 6h 37m.

Three cabin classes are available on flights from Panama City to San Diego:

• Economy Class
• Business Class
• First Class

A nonstop flight from Panama City to San Diego takes 6h 37m, covering 2,910 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Round-trip flights from Panama City to San Diego range from $654 to $870, with an average of $716 over the past 12 months. Anything below $654 counts as a good deal.

On this route, nonstop and layover fares are close on average, with nonstop at $714 round-trip and layover options via Houston George Bush Intcntl (IAH) at $716.

The Boeing 737 MAX 9 family is used most often on this route, operated mainly by Copa Airlines and United Airlines. Other aircraft seen on the route include Boeing 737-900 variants.

Afternoon is the busiest departure period on Panama City to San Diego flights, with 100% of flights leaving in that window. Morning departures account for 0%, evening flights for 0%, and night flights for 0%.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $695 to $3,083. That means the highest observed fare was about 4x higher than the lowest one.

One-way fares from Panama City to San Diego are currently lower than usual. Average one-way flight prices are about $463, which is 21% below the typical average for this route.

San Diego Airport (SAN) hosts 5 major car rental companies, with daily rates averaging $53 for economy cars. Top options include:

• Dollar
• Europcar
• Payless
• Hertz
• Thrifty

Flights from Panama City to San Diego usually depart from Panama City Tocumen Intl (PTY) and arrive at San Diego (SAN).

One-stop flights from Panama City to San Diego most commonly connect through:

• Houston George Bush Intcntl (IAH) - 88% of one-stop connections
• Miami (MIA) - 9% of one-stop connections
• Los Angeles (LAX) - 3% of one-stop connections

Yes. Flexible dates can save you up to 22% on flights from Panama City to San Diego. Saturday is the cheapest departure day at $643 round-trip on average, while Wednesday is the most expensive at $815, a difference of $172.

Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

Only Copa Airlines operates flights between Panama City and San Diego.

Flying via Houston George Bush Intcntl (IAH) gives the shortest average 1-stop total travel time at 9h 36m, compared with 12h 43m via Los Angeles (LAX) and 13h 27m via Miami (MIA).

San Diego is 3 hours behind Panama City (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

Some of the most popular sights in San Diego are Gaslamp Quarter, San Diego Convention Center and SeaWorld San Diego. These are among the most viewed places in San Diego on KAYAK.

Among airlines operating Panama City to San Diego flights:

• Copa Airlines: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a cabin bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.