$358 Find Cheap Flights from Panama City to San Diego - Compare and Save

Among airlines operating Panama City to San Diego flights:

• Copa Airlines: offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Only Copa Airlines operates flights between Panama City and San Diego.

Flights from Panama City to San Diego usually depart from Panama City Tocumen Intl (PTY) and arrive at San Diego (SAN).

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a cabin bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route and airline, so travelers should check the fare details before booking.

Two cabin classes are available on flights from Panama City to San Diego:

• Economy Class
• Business Class

On this route, layover flights are cheaper than nonstop options on average. Layover fares average $560 round-trip via San Francisco (SFO), compared to $707 for nonstop.

The Boeing 737 MAX 9 family is used most often on this route, operated mainly by Copa Airlines and United Airlines. Other aircraft seen on the route include Boeing 737-900 variants.

One-stop flights from Panama City to San Diego most commonly connect through:

• Houston George Bush Intcntl (IAH) - 78% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) - 11% of one-stop connections
• Miami (MIA) - 5% of one-stop connections
• Los Angeles (LAX) - 3% of one-stop connections

Houston George Bush Intcntl (IAH) handles the largest share of one-stop connections on this route.

Yes. Being flexible with your travel dates can save you up to 24% on the Panama City to San Diego route. Friday is the cheapest departure day at $625 round-trip on average, while Wednesday is the most expensive at $815, a difference of $190. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Afternoon is the busiest departure period on Panama City to San Diego flights, with 100% of flights leaving in that window. Morning departures account for 0%, evening flights for 0%, and night flights for 0%.

Some of the most popular sights in San Diego are Gaslamp Quarter, San Diego Convention Center and SeaWorld San Diego. These are among the most viewed places in San Diego on KAYAK.

These are the earliest and latest flight times available from Panama City to San Diego:

• Earliest: departs at 1:45 pm and lands at 8:22 pm
• Latest: departs at 1:54 pm and lands at 8:31 pm.

The flight takes about 6h 37m.

A nonstop flight from Panama City to San Diego takes 6h 37m, covering 2,910 miles.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $620 to $5,031. That means the highest observed fare was about 8x higher than the lowest one.

One-way fares from Panama City to San Diego are currently lower than usual. Average one-way flight prices are about $365, which is 35% below the typical average for this route.

Flying via Houston George Bush Intcntl (IAH) gives the shortest average 1-stop total travel time at 9h 40m, compared with 11h 17m via San Francisco (SFO) and 12h 43m via Los Angeles (LAX).

San Diego is 2 hours behind Panama City (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

San Diego Airport (SAN) hosts 5 major car rental companies, with daily rates starting from around $14 for economy cars. Top options include:
• Dollar
• Payless
• Europcar
• Thrifty
• Fox

Round-trip flights from Panama City to San Diego range from $568 to $841, with an average of $707 over the past 12 months. Anything below $568 counts as a good deal.