$245 Find Cheap Flights from Panama to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Diego departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Diego, as well as popular online travel agencies
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Cheap Flights from Panama to San Diego

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Diego

Sun, Dec 28 - Fri, Jan 2
Copa Airlines Logo
1:45 pm - 5:37 pmPTY-SAN
6h 52mnonstop
Copa Airlines Logo
8:16 pm - 5:20 amSAN-PTY
6h 04mnonstop
$429Copa Airlines
Find Deal
Tue, Jan 13 - Mon, Jan 19
United Airlines Logo
4:41 pm - 11:05 amPTY-SAN
21h 24m1 stop
United Airlines Logo
8:00 am - 7:38 pmSAN-PTY
8h 38m1 stop
$434United Airlines
Find Deal
Sun, Dec 28 - Sun, Jan 4
United Airlines Logo
4:41 pm - 8:16 pmPTY-SAN
30h 35m1 stop
United Airlines Logo
8:45 pm - 5:07 pmSAN-PTY
17h 22m2 stops
$450United Airlines
Find Deal
Fri, Dec 12 - Sat, Jan 3
United Airlines Logo
11:35 am - 12:15 amPTY-SAN
15h 40m2 stops
United Airlines Logo
6:55 pm - 2:45 pmSAN-PTY
16h 50m2 stops
$461United Airlines
Find Deal
Fri, Jan 16 - Wed, Jan 21
Delta Logo
3:20 pm - 7:41 pmPTY-SAN
31h 21m1 stop
Delta Logo
2:20 pm - 1:55 pmSAN-PTY
20h 35m1 stop
$541Delta
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Tue, Dec 16 - Tue, Dec 23
Copa Airlines Logo
1:45 pm - 5:37 pmPTY-SAN
6h 52mnonstop
Copa Airlines Logo
8:12 pm - 5:20 amSAN-PTY
6h 08mnonstop
$637Copa Airlines
Find Deal
Fri, Jan 16 - Thu, Jan 22
Delta Logo
3:20 pm - 5:41 pmPTY-SAN
29h 21m1 stop
Delta Logo
2:20 pm - 1:55 pmSAN-PTY
20h 35m1 stop
$645Delta
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Sat, Mar 14 - Thu, Mar 19
American Airlines Logo
3:50 pm - 11:45 amPTY-SAN
21h 55m1 stop
American Airlines Logo
1:25 pm - 2:20 pmSAN-PTY
22h 55m1 stop
$669American Airlines
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Sat, Mar 14 - Thu, Mar 19
American Airlines Logo
1:50 pm - 9:25 amPTY-SAN
21h 35m2 stops
American Airlines Logo
11:00 pm - 12:10 pmSAN-PTY
11h 10m1 stop
$673American Airlines
Find Deal
Sat, Mar 14 - Thu, Mar 19
Avianca Logo
7:50 pm - 11:40 pmPTY-SAN
29h 50m3 stops
Avianca Logo
6:30 am - 2:55 pmSAN-PTY
30h 25m3 stops
$961Avianca
Find Deal

Everything you should know

When to travel
October
Cheapest • 25% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Cheapest round-trip
$429
Overall average: $620
Copa Airlines
Sun 12/28Fri 1/2
PTY - SAN • Non-stop
Cheapest one-way
$245
Typical prices: $358-$409
Copa Airlines
Mon 11/17
PTY - SAN • Non-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Diego!
Booking Insights

KAYAK's insights & trends for flights to San Diego

Get data-powered insights and trends for flights to San Diego to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Diego is October, where tickets cost $406 on average for one-way flights. On the other hand, the most expensive months are January and February, where the average cost of tickets from Panama is $715 and $674 respectively. For return trips, the best month to travel is October with an average price of $406.

How far in advance should I book a flight to San Diego?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to San Diego, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 57 days before departure.

Good to know

Low seasonMarch
Cheapest flight$245
Best time to beat the crowds but there is an average 12% increase in price.
Most popular time to fly with an average 14% increase in price.
Flight from Panama City to San Diego

FAQs - booking San Diego flights

  • How far is San Diego Airport from central San Diego?

    The distance between San Diego Airport and downtown San Diego is 3 miles.

  • What is the name of San Diego’s airport?

    San Diego is served by San Diego Airport, also commonly referred to as Lindbergh Field, San Diego, or San Diego Intl. The airport code is SAN.

  • How much is a flight to San Diego?

    On average, a flight to San Diego costs $418. The cheapest price found on KAYAK in the last 2 weeks cost $270 and departed from Panama City Tocumen Intl Airport.

  • What is the cheapest day to fly to San Diego?

    Based on KAYAK data, the cheapest day to fly to San Diego is Wednesday where tickets can be as cheap as $235. On the other hand, the most expensive day to fly is Thursday, where prices are $668 on average.

  • How does KAYAK find such low prices on flights to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to San Diego?

    The cheapest time of day to fly to San Diego is generally in the afternoon, when flights cost $319 on average. The most expensive time of day to fly to San Diego is generally at night, which is peak travel time and where the average cost of a ticket is $1,009.

Top tips for finding cheap flights to San Diego

  • Looking for cheap airfare to San Diego? 25% of our users found round-trip tickets to San Diego for the following prices or less: From Panama City $481
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Diego flight deals.

Reviews of the top airlines flying from Panama to San Diego

 
See real verified KAYAK customer reviews for airlines flying to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Diego. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1561 reviews
7.4Comfort
6.8Entertainment
6.9Food
8.1Crew
7.8Boarding
Airline reviews

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

6.0 GoodZach, Oct 2025DEN - PTY
Read more Copa Airlines reviews

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Some of the Air hostesses are not that friendly. Need improvement

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

Very happy with my flight. I would definitely recommend it.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

7 hours delayed due to operational issues on United’s end. Basically laziness.

Flight from Rome to SFO was excellent compared To our flight to Europe from SFO. The food was much tastier. You can see how UNITED is skimping, though. Instead of getting something mid flight you had to ask for it. It was not automatically served. There was a cookie at the end of the arrival meal, for example that tasted like it just came out of a box. They used to serve a little container of nuts, now … a tiny container of nuts, mixed with pretzels. This was business class that you really have to pay for! But this is minor complaints compared to the overall. My major complaint is the position of the even numbered seats by the windows. You have to turn around to see your window & the positioning as some other controls are harder to get at. This is compared to the odd number seat that are perfectly aligned.

The food quality sucks. One must starve if they do not eat flesh Or wheat based products Some variety would be expected. The trivial amount of snacks and or food is inhumane

Flight was timely, relatively comfortable, with decent entertainment and food served. Only problem encountered was with the free messaging which I highly appreciate, but it did not work from iphone to non-iphones.

The internet service I paid for didn’t work at all and the flight crew was not very friendly.

Subject: Formal Complaint: Discriminatory and Unprofessional Conduct – Request for Immediate Action & Compensation Dear [Airline Customer Relations Team], I am writing to file a formal complaint regarding my recent travel experience with [Airline], which was by far the worst I have ever encountered. What occurred was not only unprofessional, but in several instances discriminatory, unsafe, and unacceptable. On the first leg of my trip, I arrived only four minutes past check-in. Instead of making any attempt to resolve the matter, your representative flatly denied me boarding and made me wait while she attended to passengers who arrived after me. By the time a manager intervened, it was too late to board, costing me time, money, and unnecessary frustration. The second leg of my trip (Chicago–San Francisco) raised even more serious concerns. From the outset, it was apparent that the staff—particularly two attendants—prioritized Caucasian passengers while dismissing African American and minority passengers. • When a Caucasian passenger in the exit row refused to comply with federal safety requirements, I, as a first responder, immediately offered to switch seats and assume the responsibility. My offer was blatantly ignored, and instead, a Caucasian passenger seated further up was chosen. This was discriminatory and deeply insulting, especially as I was actively de-escalating the situation that could have delayed the flight further. • During a lengthy tarmac delay of over 90 minutes, passengers were given conflicting and unreasonable instructions that created unnecessary distress and tension. • Throughout the flight, a visibly intoxicated passenger directly in front of me was disruptive, rude to others, failed to comply with seatbelt and electronic device rules, and yet faced no enforcement from the crew. In stark contrast, I was singled out for repeated compliance checks even though I was following every rule. This unequal treatment was so obvious that multiple passengers around me spoke up in my defense. This pattern of behavior demonstrated a clear lack of professionalism, disregard for passenger safety, and discriminatory treatment. I expect far better from an airline of your stature. As a paying customer subjected to this unacceptable treatment, I am formally requesting: 1. A full investigation into the conduct of the staff on both flights. 2. A written apology acknowledging the discriminatory and unprofessional behavior I endured. 3. Appropriate compensation for the distress, inconvenience, and mishandling of my travel. If this matter is not addressed promptly and thoroughly, I will have no choice but to escalate my complaint further, including filing with the U.S. Department of Transportation and sharing my experience through other channels. I trust [Airline] will take this complaint seriously and provide a timely resolution.

Check in was quick and easy during early hours. Flight was on time, and customer services was a plus.

I understand that the food on the airplane wouldn’t be fantastic. However, it wasn’t good at all. 😭

The flight was comfortable with the exit row and great service

Plane was crowded and even when we hit altitude, the plane was hot, not enough air flow.

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Everything you need to know for your flight to San Diego

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