$338 Find Cheap Flights from Panama to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Diego departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Diego, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama to San Diego

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Diego

Thu, Jul 2 - Fri, Jul 10
United Airlines Logo
7:55 am - 11:54 pm
PTY
-
SAN
17h 59m
2 stops
United Airlines Logo
6:55 pm - 2:14 pm
SAN
-
PTY
17h 19m
2 stops
$717United Airlines
Thu, Jul 2 - Fri, Jul 10
United Airlines Logo
10:00 am - 5:41 pm
PTY
-
SAN
9h 41m
1 stop
United Airlines Logo
7:41 pm - 6:37 pm
SAN
-
PTY
20h 56m
2 stops
$719United Airlines
Wed, Jul 22 - Sun, Jul 26
United Airlines Logo
3:30 pm - 9:59 am
PTY
-
SAN
20h 29m
2 stops
United Airlines Logo
8:32 pm - 6:37 pm
SAN
-
PTY
20h 05m
2 stops
$720United Airlines
Thu, Jul 2 - Fri, Jul 10
United Airlines Logo
7:55 am - 11:54 pm
PTY
-
SAN
17h 59m
2 stops
United Airlines Logo
7:41 pm - 2:14 pm
SAN
-
PTY
16h 33m
2 stops
$721United Airlines
Thu, Jul 2 - Fri, Jul 10
United Airlines Logo
10:00 am - 9:24 pm
PTY
-
SAN
13h 24m
1 stop
United Airlines Logo
3:10 pm - 2:14 pm
SAN
-
PTY
21h 04m
1 stop
$722United Airlines
Thu, Jul 2 - Fri, Jul 10
United Airlines Logo
7:55 am - 5:41 pm
PTY
-
SAN
11h 46m
1 stop
United Airlines Logo
6:55 pm - 4:12 pm
SAN
-
PTY
19h 17m
2 stops
$724United Airlines
Sat, Jul 25 - Wed, Jul 29
American Airlines Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
American Airlines Logo
4:22 pm - 12:14 pm
SAN
-
PTY
17h 52m
2 stops
$733American Airlines
Tue, Jul 21 - Tue, Jul 28
United Airlines Logo
3:30 pm - 7:50 pm
PTY
-
SAN
30h 20m
1 stop
United Airlines Logo
3:10 pm - 6:37 pm
SAN
-
PTY
25h 27m
1 stop
$736United Airlines
Mon, Aug 10 - Mon, Aug 17
Copa Airlines Logo
2:01 pm - 6:30 pm
PTY
-
SAN
6h 29mnonstop
Copa Airlines Logo
8:58 pm - 5:20 am
SAN
-
PTY
6h 22mnonstop
$741Copa Airlines
Wed, Jul 22 - Sun, Jul 26
Copa Airlines Logo
2:01 pm - 6:30 pm
PTY
-
SAN
6h 29mnonstop
Copa Airlines Logo
10:00 pm - 6:22 am
SAN
-
PTY
6h 22mnonstop
$747Copa Airlines
Booking Insights

KAYAK's insights & trends for flights to San Diego

Get data-powered insights and trends for flights to San Diego to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest flight to San Diego?

These are the best round-trip prices found by users searching on KAYAK in the last 72 hours.

In the last 3 days, the cheapest flight deal to San Diego was found on the route from Panama City, at $717 return. The most popular connection is from San Francisco to San Diego and KAYAK users have found round-trip deals for as low as $109 in the last 3 days.

What is the cheapest day to fly to San Diego?

The average price of all round-trip flights to San Diego clicked on KAYAK for each day over the last 12 months.

Based on KAYAK data, the cheapest day to fly to San Diego is Monday where round-trip tickets can be as cheap as $334. On the other hand, the most expensive day to fly is Wednesday, where round-trip prices are $631 on average.

What is the cheapest month to fly to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Diego is October, where tickets cost $394 on average for return flights. On the other hand, the most expensive months are April and February, where the average cost of tickets from Panama is $784 and $722 respectively. For one-way flights, the best month to travel is October with an average price of $394.

What is the cheapest time of day to fly to San Diego?

The average price for all round-trip flights to San Diego depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to San Diego is generally in the afternoon, when round-trip flights cost $417 on average. The most expensive time of day to fly to San Diego is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $417.

Good to know

Low seasonApril
Cheapest flight$338
Best time to beat the crowds but there is an average 34% increase in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Panama City to San Diego

FAQs - booking San Diego flights

  • What is the cheapest flight to San Diego?

    In the last 3 days, the cheapest flight deal to San Diego was found on the route from Panama City, at $717 return. The most popular connection is from San Francisco to San Diego and KAYAK users have found round-trip deals for as low as $109 in the last 3 days.

  • How far is San Diego Airport from central San Diego?

    The distance between San Diego Airport and downtown San Diego is 3 miles.

  • What is the name of San Diego’s airport?

    San Diego is served by San Diego Airport, also commonly referred to as Lindbergh Field, San Diego, or San Diego Intl. The airport code is SAN.

  • How much is a flight to San Diego?

    On average, a flight to San Diego costs $686. The cheapest price found on KAYAK in the last 2 weeks cost $516 and departed from Panama City Tocumen Intl Airport.

  • How does KAYAK find such low prices on flights to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to San Diego

  • Looking for cheap airfare to San Diego? 25% of our users found round-trip tickets to San Diego for the following prices or less: From Panama City $516
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Diego flight deals.

Reviews of the top airlines flying from Panama to San Diego

 
See real verified KAYAK customer reviews for airlines flying to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Diego. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1582 reviews
6.8Entertainment
7.4Comfort
6.8Food
7.8Boarding
8.1Crew
Airline reviews

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

2.0 MediocreFred, May 2026
UIO - PTY
Read more Copa Airlines reviews

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Seats were not super comfortable and food was not good at all. If I had a chance I would definitely fly a different airline. Of course they are better than any budget airline, but not by much.

Flew steerage class. Short on leg room unless you pay more. No window unless you pay more. Etc. United is trying to squeeze every cent from you. It doesn’t make for any loyalty.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

Outstanding service, great food, friendly & efficient crew, safe & comfortable flight

Staff were not attentive, wifi did not work, cut my head in the bathroom due to the position of the soap on the sink, had blood running down my face, told staff, they had no expression no sympathy, didn't even say "sorry", they said "oh we will have a look at that" about 10 mins later the purser brought me a bandaid, still no sorry.... Shocking

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

The flight was delayed from take off because only one runway was operational in San Francisco.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Dinner was good, but the breakfast served in the morning was horrible.

Packed in plane small uncomfortable seats elbow to elbow nobody wants to be in that situation for the money they paid

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Julian
National City
Borrego Springs
Poway
Alpine
Lemon Grove
Santee

Everything you need to know for your flight to San Diego

Information on the airport you'll fly into in San Diego