$334 Find Cheap Flights from Panama to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Diego departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Diego, as well as popular online travel agencies
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Cheap Flights from Panama to San Diego

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Diego

Thu, Oct 30 - Wed, Nov 5
United Airlines Logo
7:55 am - 7:52 pmPTY-SAN
13h 57m2 stops
United Airlines Logo
1:47 pm - 2:45 pmSAN-PTY
21h 58m1 stop
$412United Airlines
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Fri, Sep 19 - Fri, Sep 26
American Airlines Logo
3:31 pm - 9:52 amPTY-SAN
20h 21m2 stops
American Airlines Logo
5:15 pm - 2:31 pmSAN-PTY
19h 16m2 stops
$423American Airlines
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Mon, Sep 15 - Sat, Sep 20
United Airlines Logo
3:30 pm - 9:09 amPTY-SAN
19h 39m2 stops
United Airlines Logo
7:21 pm - 6:37 pmSAN-PTY
21h 16m2 stops
$430United Airlines
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Wed, Aug 27 - Wed, Sep 3
United Airlines Logo
3:35 pm - 7:55 amPTY-SAN
18h 20m1 stop
United Airlines Logo
10:38 am - 8:10 pmSAN-PTY
31h 32m1 stop
$447United Airlines
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Fri, Oct 31 - Tue, Nov 18
United Airlines Logo
7:55 am - 11:44 pmPTY-SAN
17h 49m2 stops
United Airlines Logo
5:55 pm - 7:38 pmSAN-PTY
22h 43m3 stops
$450United Airlines
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Mon, Aug 25 - Sun, Aug 31
American Airlines Logo
3:30 pm - 11:20 amPTY-SAN
21h 50m2 stops
American Airlines Logo
10:17 pm - 2:30 pmSAN-PTY
14h 13m1 stop
$460American Airlines
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Fri, Sep 19 - Fri, Sep 26
United Airlines Logo
10:00 am - 8:04 pmPTY-SAN
12h 04m1 stop
United Airlines Logo
7:20 pm - 2:14 pmSAN-PTY
16h 54m2 stops
$461United Airlines
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Wed, Aug 27 - Wed, Sep 3
Copa Airlines Logo
1:15 pm - 5:44 pmPTY-SAN
6h 29mnonstop
Copa Airlines Logo
9:08 pm - 5:25 amSAN-PTY
6h 17mnonstop
$482Copa Airlines
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Fri, Sep 12 - Fri, Sep 19
Copa Airlines Logo
1:15 pm - 5:50 pmPTY-SAN
6h 35mnonstop
Copa Airlines Logo
9:08 pm - 5:25 amSAN-PTY
6h 17mnonstop
$484Copa Airlines
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Fri, Dec 12 - Sat, Jan 3
Delta Logo
3:17 pm - 10:58 pmPTY-SAN
10h 41m1 stop
Delta Logo
9:50 pm - 1:55 pmSAN-PTY
13h 05m1 stop
$592Delta
Find Deal
Booking Insights

KAYAK's insights & trends for flights to San Diego

Get data-powered insights and trends for flights to San Diego to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Diego is October, where tickets cost $407 on average for return flights. On the other hand, the most expensive months are January and December, where the average cost of tickets from Panama is $730 and $713 respectively. For one-way flights, the best month to travel is October with an average price of $407.


Good to know

Low seasonMarch
Cheapest flight$334
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly and prices are also 32% lower on average.
Flight from Panama City to San Diego

FAQs - booking San Diego flights

  • How far is San Diego Airport from central San Diego?

    The distance between San Diego Airport and downtown San Diego is 3 miles.

  • What is the name of San Diego’s airport?

    San Diego is served by San Diego Airport, also commonly referred to as Lindbergh Field, San Diego, or San Diego Intl. The airport code is SAN.

  • How much is a flight to San Diego?

    On average, a flight to San Diego costs $418. The cheapest price found on KAYAK in the last 2 weeks cost $319 and departed from Panama City Tocumen Intl Airport.

  • What is the cheapest day to fly to San Diego?

    Based on KAYAK data, the cheapest day to fly to San Diego is Wednesday where round-trip tickets can be as cheap as $235. On the other hand, the most expensive day to fly is Thursday, where round-trip prices are $668 on average.

  • How does KAYAK find such low prices on flights to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to San Diego?

    The cheapest time of day to fly to San Diego is generally in the afternoon, when round-trip flights cost $319 on average. The most expensive time of day to fly to San Diego is generally at night, which is peak travel time and where the average cost of a ticket is $1,009.

  • How many direct flights to San Diego are there each week?

    Each week there are around 2,333 direct flights from within Panama to San Diego. The most common day for departures is Sunday, with 16% of flights taking off on this day.

Top tips for finding cheap flights to San Diego

  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Diego flight deals.

Reviews of the top airlines flying from Panama to San Diego

 
See real verified KAYAK customer reviews for airlines flying to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Diego. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1493 reviews
7.4Comfort
7.8Boarding
6.8Food
8.1Crew
6.8Entertainment
Airline reviews

horrible service, food was an embarrassment, no charging for cellphones, stay away

2.0 MediocreAnonymous, Jul 2025PTY - IAD
Read more Copa Airlines reviews

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

Very happy with my flight. I would definitely recommend it.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

It was ok. However, the food was quite poor since I don't eat pasta.

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

Enforce the boarding process by group numbers. Tell people to stay seated during the meal/drink distribution. It took forever to get food and drinks because people would not stay out the isle and let the crew do their jobs. Everyone wanted to go to the bathroom forcing the crew to enter and leave the isle constantly so people can pass. Tell people to keep their electronics off speaker mode. No one wants to hear phone conversations and music playing.

The flight was delayed twice and I could not speak with anyone at the airport about checking in. The phone number to Copa - the customer service agents were polite. They are just limited at helping because they are not at the airport

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

Ok. Get a different kosher caterer. The food was odd.

Our experience on United Airlines was extremely poor. The plane was extremely cold throughout our entire flight- which multiple people complained about- and we had to wait 2 hours to get a blanket which was too thin and barely helped warm us up. As well as this, none of the entertainment features were working so we had to sit through a roughly 10 hour flight with nothing to keep our attention, including the actual flight path screen. It was an extremely disappointing experience and I would hope that this gets fixed if we ever choose United Airlines again.

I really enjoyed flying with United airlines amazing experience , good customer service and great food

1.It will be better if sandwich is warm. 2.The food is too salty. 3.Breakfast needs some vegetables or fruits.

Boarded plane and then delayed 1.5 hours while on the plane

It was all good flight was on time, service was good I enjoyed a few movies and everything was smooth

Horrific. They missed my connecting flight to San Diego. I didn’t get there until Monday at 9am when I had a mandatory court settlement conference scheduled at 6am since we had parties on the east coast. This caused many issues. All because United apparently forgot to hold the doors open until my flight landed that only had a 10 minute delay. This was the last flight to Southern California. So I couldn’t even rent a car to finish the trip. United cannot be trusted when traveling on specific days and times since weather didn’t have anything to do with the delays.

My flight was delayed a very short period of time but they did not hold my connecting flight to San Diego, also through United. So they closed the doors before we got off our plane. They would only have to help the door open for another five to ten minutes. So I missed a court deadline for a manditory mediation settlement conference for my client. I had to get an associate to be there in person and be on the phone with him relaying what he needs to do the entire time. The court was very upset with me and so was my client. United cannot be trusted.

We were given vouchers we couldn’t use with a 5.5 hour delay

Really good 😊 the woman at the gate entrance was a little rude checking in our carry-on but i dont think she worked for the airline, she worked for the airport at sacramento, other than that amazing.

Everything you need to know for your flight to San Diego

Information on the airport you'll fly into in San Diego

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