$359 Find Cheap Flights from Panama to San Diego

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Diego departing on 4/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Diego, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama to San Diego

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Diego

Wed, May 27 - Sun, May 31
Copa Airlines Logo
1:39 pm - 6:30 pm
PTY
-
SAN
6h 51mnonstop
Copa Airlines Logo
10:00 pm - 6:07 am
SAN
-
PTY
6h 07mnonstop
$494Copa Airlines
Fri, May 29 - Tue, Jun 2
GOL Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
GOL Logo
1:21 pm - 12:13 pm
SAN
-
PTY
20h 52m
2 stops
$515GOL
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 11:18 am
PTY
-
SAN
24h 04m
1 stop
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$518American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 11:18 am
PTY
-
SAN
24h 04m
1 stop
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$519American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 11:51 am
PTY
-
SAN
24h 37m
2 stops
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$521American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$522American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$523American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$524American Airlines
Wed, May 27 - Sun, May 31
American Airlines Logo
1:14 pm - 11:51 am
PTY
-
SAN
24h 37m
2 stops
American Airlines Logo
12:36 pm - 12:13 pm
SAN
-
PTY
21h 37m
1 stop
$525American Airlines
Tue, May 26 - Sat, May 30
GOL Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
GOL Logo
1:21 pm - 12:13 pm
SAN
-
PTY
20h 52m
2 stops
$569GOL
Booking Insights

KAYAK's insights & trends for flights to San Diego

Get data-powered insights and trends for flights to San Diego to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest flight to San Diego?

These are the best round-trip prices found by users searching on KAYAK in the last 72 hours.

In the last 3 days, the cheapest flight deal to San Diego was found on the route from Panama City, at $494 return. The most popular connection is from Chicago to San Diego and KAYAK users have found round-trip deals for as low as $177 in the last 3 days.

What is the cheapest day to fly to San Diego?

The average price of all round-trip flights to San Diego clicked on KAYAK for each day over the last 12 months.

Based on KAYAK data, the cheapest day to fly to San Diego is Monday where round-trip tickets can be as cheap as $334. On the other hand, the most expensive day to fly is Friday, where round-trip prices are $443 on average.

What is the cheapest month to fly to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Diego is October, where tickets cost $394 on average for return flights. On the other hand, the most expensive months are February and March, where the average cost of tickets from Panama is $722 and $710 respectively. For one-way flights, the best month to travel is October with an average price of $394.

What is the cheapest time of day to fly to San Diego?

The average price for all round-trip flights to San Diego depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to San Diego is generally in the afternoon, when round-trip flights cost $344 on average. The most expensive time of day to fly to San Diego is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $344.

Good to know

Low seasonApril
Cheapest flight$359
Best time to beat the crowds but there is an average 10% increase in price.
Most popular time to fly with an average 3% increase in price.
Flight from Panama City to San Diego

FAQs - booking San Diego flights

  • What is the cheapest flight to San Diego?

    In the last 3 days, the cheapest flight deal to San Diego was found on the route from Panama City, at $494 return. The most popular connection is from Chicago to San Diego and KAYAK users have found round-trip deals for as low as $177 in the last 3 days.

  • How far is San Diego Airport from central San Diego?

    The distance between San Diego Airport and downtown San Diego is 3 miles.

  • What is the name of San Diego’s airport?

    San Diego is served by San Diego Airport, also commonly referred to as Lindbergh Field, San Diego, or San Diego Intl. The airport code is SAN.

  • How much is a flight to San Diego?

    On average, a flight to San Diego costs $746. The cheapest price found on KAYAK in the last 2 weeks cost $436 and departed from Panama City Tocumen Intl Airport.

  • How does KAYAK find such low prices on flights to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to San Diego

  • Looking for cheap airfare to San Diego? 25% of our users found round-trip tickets to San Diego for the following prices or less: From Panama City $748
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Diego flight deals.

Reviews of the top airlines flying from Panama to San Diego

 
See real verified KAYAK customer reviews for airlines flying to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Diego. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1572 reviews
7.4Comfort
6.8Food
6.8Entertainment
7.8Boarding
8.1Crew
Airline reviews

Do not book it’s a scam! They stole $1200 from me

2.0 MediocreTalicia, Mar 2026
PTY - RDU
Read more Copa Airlines reviews

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Some of the Air hostesses are not that friendly. Need improvement

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

The head flight attendant made the trip excellent. He was very accommodating.

The economy seats on the 777 was not as cramped as I had feared, but the food was terrible.

Terrible experience! delay 2 time and say i dont have ticket

It was amazing. I had several upgraded seats on my flight out. Everything went smooth with no delays.

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

Flight attendants were friendly & good service, food sucks, seats uncomfortable, not many Asian movies or shows flying from Hong Kong

Flight attendants had a little attitude. Food tastes no good.

Overall we had a good experience during our flight from San Francisco to Houston.

it was a very short flight so my expectations were low.

Good flight. However, when booked flight with United, assumed the layover included by United in San Francisco of 1 hr and 40 minutes was sufficient . Not so and would recommend at least 2 hours or more. Needed to go through US immigration (very long lineups), then pick up bags, take all the way to another terminal, running because we did not have sufficient time. We made the flight because they held the door for us but luggage didn’t follow.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
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National City
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Everything you need to know for your flight to San Diego

Information on the airport you'll fly into in San Diego