$353 Find Cheap Flights from Panama to San Diego - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Diego departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Diego

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Diego, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Diego, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama to San Diego

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Diego that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Diego

Sun, Aug 16 - Sun, Aug 23
Copa Airlines Logo
2:01 pm - 6:30 pm
PTY
-
SAN
6h 29mnonstop
Copa Airlines Logo
10:00 pm - 6:22 am
SAN
-
PTY
6h 22mnonstop
$601Copa Airlines
Sat, Sep 5 - Sat, Sep 26
United Airlines Logo
3:30 pm - 1:17 pm
PTY
-
SAN
23h 47m
1 stop
United Airlines Logo
6:28 pm - 2:14 pm
SAN
-
PTY
17h 46m
2 stops
$607United Airlines
Sun, Aug 16 - Sun, Aug 23
United Airlines Logo
3:30 pm - 11:35 am
PTY
-
SAN
22h 05m
2 stops
United Airlines Logo
2:24 pm - 6:37 pm
SAN
-
PTY
26h 13m
2 stops
$617United Airlines
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
10:00 am - 12:31 am
PTY
-
SAN
16h 31m
2 stops
United Airlines Logo
3:56 pm - 2:14 pm
SAN
-
PTY
20h 18m
3 stops
$620United Airlines
Fri, Sep 25 - Mon, Sep 28
United Airlines Logo
10:00 am - 5:46 pm
PTY
-
SAN
9h 46m
1 stop
United Airlines Logo
6:28 pm - 6:37 pm
SAN
-
PTY
22h 09m
2 stops
$631United Airlines
Fri, Oct 23 - Wed, Oct 28
American Airlines Logo
3:35 pm - 11:25 am
PTY
-
SAN
21h 50m
1 stop
American Airlines Logo
4:28 pm - 2:00 pm
SAN
-
PTY
19h 32m
2 stops
$636American Airlines
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
3:30 pm - 3:40 pm
PTY
-
SAN
26h 10m
1 stop
United Airlines Logo
3:00 pm - 2:14 pm
SAN
-
PTY
21h 14m
1 stop
$640United Airlines
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
3:30 pm - 3:40 pm
PTY
-
SAN
26h 10m
1 stop
United Airlines Logo
3:00 pm - 2:14 pm
SAN
-
PTY
21h 14m
1 stop
$651United Airlines
Thu, Oct 1 - Mon, Oct 5
United Airlines Logo
10:00 am - 1:17 pm
PTY
-
SAN
29h 17m
1 stop
United Airlines Logo
2:24 pm - 2:14 pm
SAN
-
PTY
21h 50m
2 stops
$662United Airlines
Sat, Nov 14 - Mon, Dec 14
Copa Airlines Logo
1:45 pm - 5:15 pm
PTY
-
SAN
6h 30mnonstop
Copa Airlines Logo
10:00 pm - 7:10 am
SAN
-
PTY
6h 10mnonstop
$668Copa Airlines
Booking Insights

KAYAK's insights & trends for flights to San Diego

Get data-powered insights and trends for flights to San Diego to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest day to fly to San Diego?

The average price of all round-trip flights to San Diego clicked on KAYAK for each day over the last 12 months.

Based on KAYAK data, the cheapest day to fly to San Diego is Monday where round-trip tickets can be as cheap as $334. On the other hand, the most expensive day to fly is Wednesday, where round-trip prices are $714 on average.

What is the cheapest month to fly to San Diego?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights to San Diego, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Diego is January, where tickets cost $174 on average for return flights. On the other hand, the most expensive months are June and April, where the average cost of tickets from Panama is $1,104 and $643 respectively. For one-way flights, the best month to travel is November with an average price of $224.

What is the cheapest time of day to fly to San Diego?

The average price for all round-trip flights to San Diego depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to San Diego is generally in the afternoon, when round-trip flights cost $494 on average. The most expensive time of day to fly to San Diego is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $494.

Good to know

Low seasonJune
Cheapest flight$353
Best time to beat the crowds but there is an average 75% increase in price.
Most popular time to fly and prices are also 19% lower on average.
Flight from Panama City to San Diego

FAQs - booking San Diego flights

  • How far is San Diego Airport from central San Diego?

    The distance between San Diego Airport and downtown San Diego is 3 miles.

  • What is the name of San Diego’s airport?

    San Diego is served by San Diego Airport, also commonly referred to as Lindbergh Field, San Diego, or San Diego Intl. The airport code is SAN.

  • How much is a flight to San Diego?

    On average, a flight to San Diego costs $671. The cheapest price found on KAYAK in the last 2 weeks cost $378 and departed from Panama City Tocumen Intl Airport.

  • How does KAYAK find such low prices on flights to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to San Diego

  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Diego flight deals.

Reviews of the top airlines flying from Panama to San Diego

 
See real verified KAYAK customer reviews for airlines flying to San Diego. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Diego. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Diego? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1568 reviews
7.4Comfort
6.8Entertainment
7.8Boarding
8.1Crew
6.9Food
Airline reviews

Orderly boarding, priority for platinum members, courtesy drinks from business class even when we were seating in economy.

10.0 ExcellentAnonymous, Jun 2026
PTY - BOG
Read more Copa Airlines reviews

Orderly boarding, priority for platinum members, courtesy drinks from business class even when we were seating in economy.

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

A lot things happened in this trip.The fly should be less stress.

United has been holding my money for a cancel on another ticket they wouldn’t let me fly for going on 5 months. Terrible service I wouldn’t choose to buy tickets or fly with united again. Very bad experience generally dishonorable and poor service .

The flight got delayed. They forgot to bring the drinks when I asked for it. The toilet is messy.

This was an overnight flight, and in the morning they did know coffee service. How you can throw passengers in a San Francisco airport at 5:40 a.m. in the morning and not giving them Coffee is a crime.

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

Service was professional and quick. Premium economy seat was comfortable given the class

Like: departed and arrived on time. Unlike: Food options for purchase allways bad, 1 of 2 of the crew members not very friendly at all. Seats and leg room aweful. At this point I am thinking on switching to AA.

The staff was extremely helpful and friendly at all times! They went above and beyond to get us into an earlier flight in San Diego to make our connection in SFO possible, because our original flight did actually not make it! I did so much appreciate the UA team and how they made this possible. We also didn’t have seats together on the long flight to Singapore, but they found us seats together last moment with no additional cost! Nobody sat next to us, so that we were able to sleep! Thanks to UA for improving their service and Underpricer for booking this trip! Please be careful: 1,5 hrs for transfer in San Francisco might not be enough time in the future

Crew was great! Good meals. Had room to stretch out

Packed flight, which makes it tough on crew and boarding staff (and the customers of course). But this was great boarding, clear instructions, etc. Traveling on the weekends are always fraught with danger as you have families and less frequent flyers thus more confusion. But this flight went as planned.

Destroyed my suitcase. Tired of talking about it. Cancelling my unite mileage plus account.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
National City
Julian
Borrego Springs
Poway
Alpine
Santee
Lemon Grove

Everything you need to know for your flight to San Diego

Information on the airport you'll fly into in San Diego