$322 Find Cheap Flights from Panama to St. Louis - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to St. Louis departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results for flights to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to St. Louis, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama to St. Louis

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to St. Louis

Thu, Aug 6 - Tue, Aug 18
United Airlines Logo
9:45 am - 11:44 pm
PTY
-
STL
13h 59m
1 stop
United Airlines Logo
7:00 am - 7:31 pm
STL
-
PTY
12h 31m
1 stop
$675United Airlines
Thu, Aug 6 - Tue, Aug 18
United Airlines Logo
3:30 pm - 12:11 pm
PTY
-
STL
20h 41m
2 stops
United Airlines Logo
8:00 am - 7:31 pm
STL
-
PTY
11h 31m
2 stops
$680United Airlines
Sun, Sep 6 - Thu, Sep 10
United Airlines Logo
10:55 pm - 3:38 pm
PTY
-
STL
16h 43m
2 stops
United Airlines Logo
11:15 am - 6:37 pm
STL
-
PTY
7h 22m
1 stop
$699United Airlines
Tue, Jul 14 - Fri, Jul 17
Multiple Airlines Logo
10:25 am - 8:57 am
PTY
-
STL
22h 32m
2 stops
Multiple Airlines Logo
4:57 pm - 8:34 pm
STL
-
PTY
27h 37m
1 stop
$700Multiple Airlines
Sun, Jul 26 - Sun, Aug 2
United Airlines Logo
9:45 am - 11:44 pm
PTY
-
STL
13h 59m
1 stop
United Airlines Logo
5:59 pm - 4:12 pm
STL
-
PTY
22h 13m
2 stops
$720United Airlines
Fri, Jul 3 - Sat, Jul 11
Multiple Airlines Logo
9:48 pm - 5:37 pm
PTY
-
STL
43h 49m
2 stops
Multiple Airlines Logo
4:57 pm - 8:34 pm
STL
-
PTY
27h 37m
1 stop
$734Multiple Airlines
Tue, Jul 14 - Fri, Jul 17
United Airlines Logo
7:55 am - 9:26 pm
PTY
-
STL
13h 31m
2 stops
United Airlines Logo
7:05 pm - 2:14 pm
STL
-
PTY
19h 09m
2 stops
$741United Airlines
Tue, Jul 21 - Sat, Aug 8
American Airlines Logo
1:14 pm - 10:24 am
PTY
-
STL
21h 10m
1 stop
American Airlines Logo
11:35 am - 12:39 pm
STL
-
PTY
25h 04m
1 stop
$742American Airlines
Tue, Jul 21 - Sat, Aug 8
American Airlines Logo
1:14 pm - 8:31 am
PTY
-
STL
19h 17m
2 stops
American Airlines Logo
5:00 am - 12:39 pm
STL
-
PTY
7h 39m
1 stop
$746American Airlines
Mon, Jun 29 - Wed, Jul 8
United Airlines Logo
7:55 am - 8:42 pm
PTY
-
STL
12h 47m
1 stop
United Airlines Logo
6:14 am - 4:12 pm
STL
-
PTY
9h 58m
1 stop
$752United Airlines
Booking Insights

KAYAK's insights & trends for flights to St. Louis

Get data-powered insights and trends for flights to St. Louis to help you find the cheapest flights, the best time to fly and much more.

How long is the flight to St. Louis?

The duration of your flight to St. Louis depends on your departure and arrival airports. Obviously, any flights that include a layover will also be longer. The most popular route to St. Louis on KAYAK is from Panama City, which takes 9h 47m.

How many direct flights to St. Louis are there each day?

There are around 426 direct flights from within Panama to St. Louis every day. Most flights depart in the morning, with 32% of flights departing in the morning.

Good to know

Low seasonSeptember
Cheapest flight$322
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 5% increase in price.
Flight from Panama City to St. Louis

FAQs - booking St. Louis flights

  • How far is Lambert-St Louis Airport from central St. Louis?

    The city center of St. Louis is 13 miles from Lambert-St Louis Airport.

  • What is the name of St. Louis’s airport?

    St. Louis is served by Lambert-St Louis Airport, also commonly referred to as Lambert Field, Lambert-St Louis, St. Louis Lambert, or St. Louis Lambert Intl. The airport code is STL.

  • How does KAYAK find such low prices on flights to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many direct flights to St. Louis are there each week?

    Each week there are around 2,981 direct flights from within Panama to St. Louis. The most common day for departures is Sunday, with 16% of flights taking off on this day.

Top tips for finding cheap flights to St. Louis

  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest St. Louis flight deals.

Reviews of the top airline flying from Panama to St. Louis

 
See real verified KAYAK customer reviews for airlines flying to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to St. Louis. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9830 reviews
7.7Boarding
8.1Crew
7.3Comfort
6.6Food
7.1Entertainment
Airline reviews

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

4.0 OkayOlivia, Jun 2026
SEA - SFO
Read more United Airlines reviews

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

The pilot had to extend the flight time from san antonio to Houston to burn off fuel. This caused a lot of unnecessary stress since we had a tight connection to Aruba. And with no other flights going to Aruba we were worried about spending a night in Houston. We had to to run to our connection because of the flight crews mistake. Not happy.

Service was professional and quick. Premium economy seat was comfortable given the class

I'm a United 1K member and have ben for 10 years. The gate agent had no control over the boarding process and had us passengers queued for hours as delays were announced. On the plane, the overhead air nozzle was broken so col over was powering through on me and the passenger next to me. Not a great experience for a million miler on United. Feel free to contact me. Josh Smigel - DM426089

Like: departed and arrived on time. Unlike: Food options for purchase allways bad, 1 of 2 of the crew members not very friendly at all. Seats and leg room aweful. At this point I am thinking on switching to AA.

Over 5 hour delay with minimal updates or ability to standby for alternative flights. During boarding and 1 hr+ wait for takeoff, seats were drenched w water from air conditioning condensation and always leftover crumbs on carpet and seats

I missed my flight and had to buy new tickets Rome- Boston

The staff was extremely helpful and friendly at all times! They went above and beyond to get us into an earlier flight in San Diego to make our connection in SFO possible, because our original flight did actually not make it! I did so much appreciate the UA team and how they made this possible. We also didn’t have seats together on the long flight to Singapore, but they found us seats together last moment with no additional cost! Nobody sat next to us, so that we were able to sleep! Thanks to UA for improving their service and Underpricer for booking this trip! Please be careful: 1,5 hrs for transfer in San Francisco might not be enough time in the future

Over 2.5 hour maintenance delay on first morning flight with no acknowledgement, compensation or even gesture of good will. Aircraft had overnighted at airport so issue should have been addressed prior to boarding. Over 3.5 hours before first slow and deliberate beverage service.

I flew from Barcelona to Chicago on UA yesterday. The flight was on time, the pilots did a great job and the flight attendants were super nice. All of them. Also food was good, and the drinks, including wine were served a few times during our flight. I highly recommend this airline.

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
O'Fallon
Wentzville
Farmington
Eureka
Litchfield
Grafton
Shrewsbury
Glencoe

Everything you need to know for your flight to St. Louis

Information on the airport you'll fly into in St. Louis