$284 Find Cheap Flights from Panama to South Carolina

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KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results for flights to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to South Carolina, as well as popular online travel agencies
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Useful Info
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KAYAK's insights & trends for flights to South Carolina

Get data-powered insights and trends for flights to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How long is the flight to South Carolina?

An average nonstop flight from Panama to South Carolina takes 10h 47m, covering a distance of 1727 miles. The shortest route is Panama City (PTY) to Charleston (CHS) with an average flight time of 7h 26m.

What are the most popular destinations in South Carolina?

Based on KAYAK flight searches, the most popular destination is Charlotte (52% of total searches to South Carolina). The next most popular destinations are Charleston (18%) and Columbia (14%). Searches for flights to Greenville (9%), to Augusta (2%) and to Florence (2%) are also popular.


Good to know

Low seasonJanuary
High seasonDecember
Cheapest flight$284
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 24% increase in price.
Flight from Panama City to Charlotte

FAQs for booking flights from Panama to South Carolina

  • How does KAYAK find such low prices on flights from Panama to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest day to fly to South Carolina?

    Based on KAYAK data, the cheapest day to fly to South Carolina is Tuesday where round-trip tickets can be as cheap as $516. On the other hand, the most expensive day to fly is Sunday, where round-trip prices are $723 on average.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $469 on average. Morning departures are around 4% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $554.

Top airline flying from Panama to South Carolina

 
See real verified KAYAK customer reviews for airlines flying to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to South Carolina. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
6.5Food
7.5Boarding
8.0Crew
7.2Comfort
6.9Entertainment
Airline reviews

Paid $35 and not able to access the internet at all.

2.0 MediocreAnonymous, Apr 2025HND - JFK
Read more American Airlines reviews

Paid $35 and not able to access the internet at all.

Several delays. Next flight was worse. Did not arrive home until 2am PT

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

First world problems, but still… We were seated in first class and asked for a cocktail on a very short, 50 minute flight. After our drink order was taken, a half hour went by, and we noticed that every other person in the small plane had been served except for us. We got up to ask about it, the drinks finally came, then were taken away three minutes later since the flight was so short. Really strange situation, on the other hand, we were in Utah.

We missed our flight. The boarding pass had the wrong gate and by the time we received the text from Kayak, our flight was already gone. I’ll never use Kayak again and will go direct to the airlines in the future.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Flight was delayed bc of mechanical issue. New plane had different configuration so some seats had to be switched. They called all passengers who needed new boarding cards. They did not call us so we thought our seats were the same and fine. When we boarded they informed us our receipts had changed and we are now all sitting separate and in the back row. Both my daughters had meltdowns and started to cry and once we got on the flight, we figured out how we could sit closer to each other, but this was very upsetting.

Took off on time and successfully avoided weather that looked to be a problem along the way

Book cheap flights from Panama to South Carolina

Recent round-trip flight deals

 
These are the cheapest round-trip flights to South Carolina found on KAYAK in the last 72 hours.
7/25Fri
1 stopDelta
8h 36mPTY-CHS
8/2Sat
1 stopDelta
7h 45mCHS-PTY
$393
7/25Fri
2 stopsAmerican Airlines
18h 08mPTY-CHS
8/2Sat
1 stopAmerican Airlines
9h 15mCHS-PTY
$398
5/14Wed
2 stops
27h 54mPTY-CLT
5/18Sun
2 stops
28h 31mCLT-PTY
$431
5/14Wed
2 stops
27h 54mPTY-CLT
5/18Sun
3 stops
26h 21mCLT-PTY
$445
5/15Thu
2 stops
18h 23mPTY-CLT
5/18Sun
2 stops
31h 35mCLT-PTY
$446
5/15Thu
3 stops
20h 33mPTY-CLT
5/18Sun
2 stops
31h 35mCLT-PTY
$451
5/21Wed
1 stopUnited Airlines
29h 46mPTY-CLT
5/30Fri
1 stopUnited Airlines
26h 32mCLT-PTY
$545
6/13Fri
1 stopUnited Airlines
18h 31mPTY-CLT
6/20Fri
1 stopUnited Airlines
9h 31mCLT-PTY
$599
5/15Thu
2 stopsAvianca
15h 20mPTY-CLT
5/18Sun
2 stopsAvianca
19h 10mCLT-PTY
$932
5/17Sat
2 stopsAvianca
15h 20mPTY-CLT
5/30Fri
2 stopsAvianca
19h 10mCLT-PTY
$1,261

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Recent one-way flight deals

 
Only flying one-way? Below are some of the best deals for one-way flights to South Carolina found on KAYAK in the last 72 hours.
6/19Thu
1 stopDelta
7h 29mPTY-CLT
$284
6/20Fri
1 stopAmerican Airlines
16h 36mPTY-CLT
$296
9/2Tue
2 stopsAmerican Airlines
19h 35mPTY-CAE
$305
6/20Fri
2 stopsAmerican Airlines
14h 15mPTY-CLT
$307
6/19Thu
2 stopsAmerican Airlines
15h 45mPTY-CLT
$328
6/18Wed
2 stops
15h 18mPTY-CLT
$403
9/2Tue
1 stopDelta
8h 45mPTY-CAE
$603
6/18Wed
3 stops
19h 39mPTY-CLT
$798
6/19Thu
3 stops
35h 39mPTY-CLT
$813
6/20Fri
3 stops
30h 15mPTY-CLT
$925

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Last minute flights to South Carolina

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights to South Carolina that are departing in the next 10 days.
5/3Sat
multi-stopDelta
7h 26mPTY-CHS
5/14Wed
multi-stopDelta
7h 11mCHS-PTY
$540
5/3Sat
multi-stopAmerican Airlines
9h 36mPTY-CHS
5/14Wed
multi-stopAmerican Airlines
19h 10mCHS-PTY
$553
5/3Sat
multi-stopAmerican Airlines
19h 48mPTY-CAE
5/9Fri
multi-stopAmerican Airlines
17h 03mCAE-PTY
$674
5/3Sat
multi-stopAmerican Airlines
18h 16mPTY-CAE
5/5Mon
multi-stopAmerican Airlines
22h 42mCAE-PTY
$696
5/3Sat
multi-stopCopa Airlines
14h 13mPTY-CAE
5/5Mon
multi-stopCopa Airlines
11h 38mCAE-PTY
$1,443
5/3Sat
multi-stopUnited Airlines
14h 43mPTY-CAE
5/9Fri
multi-stopUnited Airlines
23h 41mCAE-PTY
$5,925

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Everything you need to know for your flight to South Carolina

Cabin class types available on flights to South Carolina

Cabin classes available on flights to South Carolina. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

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