$352 Find Cheap Flights from Panama City to South Carolina - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Panama City to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Sort by: Cheapest
Charleston
8h 35m2 stops
from $687per person
Myrtle Beach
7h 05m2 stops
from $814per person
Booking Insights

KAYAK's insights & trends for Panama City to South Carolina flights

Get data-powered insights and trends into flights from Panama City to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Panama City to South Carolina?

The cheapest month for flights from Panama City to South Carolina is October, when tickets cost $0 (return) on average. On the other hand, the most expensive months are March and August, when the average cost of round-trip tickets is $715 and $683 respectively.

Good to know

Low season

August

Cheapest flight

$352
Best time to beat the crowds but there is an average 14% increase in price.
Most popular time to fly and prices are also 29% lower on average.
Flight from Panama City to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Panama City to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to South Carolina

 
Need help choosing which airline to fly with from Panama City to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
American AirlinesOverall score based on 12102 reviews
6.4Food
7.9Crew
6.8Entertainment
7.2Comfort
7.4Boarding
Airline reviews

We sat on the tarmac for an hour. After our flight got delayed 30 minutes because the crew was late.

2.0 MediocreCade, Oct 2026
Read more American Airlines reviews

We sat on the tarmac for an hour. After our flight got delayed 30 minutes because the crew was late.

There was no clear update on the flight until last minute and made it an hour delay. No clear flight aircraft or incoming flight which we will be boarding. We would plan accordingly for our connecting flight. This is one one the worst service, I also had to buy an another ticket with different ai carrier. American airline was not letting me plan my trip, made us just waiting. Not a good service at all.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

Flight was good. Miss getting more options to eat than pretzels or cookies. Attendants were all wonderful.

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

The waiting area in panama was super crowded, and hot

More options for your flight from Panama City to South Carolina

Complete your trip to South Carolina with a hotel stay or car rental