$258 Find Cheap Flights from Panama City to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to South Carolina departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to South Carolina, as well as popular online travel agencies
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Best South Carolina Flight Deals from Panama City

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$376
Charleston
Charleston1 stop$376

Cheap Flights from Panama City to South Carolina

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to South Carolina

Wed, Jul 30 - Wed, Aug 6
United Airlines Logo
3:30 pm - 10:45 pmPTY-CHS
30h 15m1 stop
United Airlines Logo
7:00 am - 6:37 pmCHS-PTY
12h 37m1 stop
$376United Airlines
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Tue, Aug 5 - Sun, Aug 10
 Logo
3:20 am - 10:16 pmPTY-CLT
17h 56m2 stops
 Logo
6:00 am - 9:10 pmCLT-PTY
16h 10m2 stops
Wed, Dec 3 - Tue, Jan 13
United Airlines Logo
11:35 am - 10:50 amPTY-CLT
23h 15m1 stop
United Airlines Logo
6:30 am - 2:45 pmCLT-PTY
8h 15m1 stop
$481United Airlines
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Tue, Aug 5 - Thu, Nov 6
 Logo
10:05 pm - 5:59 pmPTY-CLT
18h 54m2 stops
 Logo
5:55 pm - 12:35 pmCLT-PTY
18h 40m2 stops
Sat, Nov 1 - Wed, Nov 5
United Airlines Logo
3:41 pm - 10:59 pmPTY-CLT
30h 18m1 stop
United Airlines Logo
11:34 am - 2:45 pmCLT-PTY
27h 11m1 stop
$503United Airlines
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Wed, Dec 3 - Tue, Jan 13
American Airlines Logo
4:15 pm - 6:40 amPTY-CLT
14h 25m2 stops
American Airlines Logo
8:59 am - 3:35 pmCLT-PTY
6h 36m1 stop
$506American Airlines
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Wed, Aug 6 - Sun, Aug 10
American Airlines Logo
3:30 pm - 6:29 amPTY-CLT
13h 59m2 stops
American Airlines Logo
5:17 am - 2:30 pmCLT-PTY
10h 13m1 stop
$529American Airlines
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Tue, Aug 5 - Thu, Nov 6
Delta Logo
2:28 pm - 11:52 pmPTY-CAE
8h 24m1 stop
Delta Logo
5:40 am - 1:52 pmCAE-PTY
8h 12m1 stop
$834Delta
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Mon, Sep 1 - Mon, Sep 8
Avianca Logo
1:30 pm - 6:53 pmPTY-CLT
28h 23m3 stops
Avianca Logo
10:33 am - 12:35 pmCLT-PTY
27h 02m3 stops
$1,090Avianca
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Mon, Sep 1 - Mon, Sep 8
Avianca Logo
1:30 pm - 6:53 pmPTY-CLT
28h 23m3 stops
Avianca Logo
10:33 am - 12:35 pmCLT-PTY
27h 02m3 stops
$1,366Avianca
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KAYAK's insights & trends for Panama City to South Carolina flights

Get data-powered insights and trends into flights from Panama City to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to South Carolina?

The average price of all round-trip flights from Panama City to South Carolina clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Panama City to South Carolina, look for departures on Wednesdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from South Carolina, Wednesday is the cheapest day to fly and Sunday is the most expensive.


Good to know

Low seasonOctober
High seasonDecember
Cheapest flight$258
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly with an average 8% increase in price.
Flight from Panama City to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Panama City to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $469 on average. Morning departures are around 4% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $554.

Reviews of the top airline flying from Panama City to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Panama City to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
6.5Food
7.5Boarding
7.2Comfort
8.0Crew
6.9Entertainment
Airline reviews

They cancelled my flight and downgraded me to economy and only gave me $250 for the downgrade

2.0 MediocreAlan, Jun 2025YVR - CLT
Read more American Airlines reviews

They cancelled my flight and downgraded me to economy and only gave me $250 for the downgrade

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

The flight crew were friendly and attentive. Food was good and they passed out ice cream and drinks awhile after Lunch was done. The ice cream was a nice treat! I found several movies to watch during the flight. There was many movies and tv shows to choose from. We flew Premium economy and there was enough leg room to be comfortable. The seats were also comfortable. I would fly AA again if the airfare isn’t expensive.

The chair cushions may need an upgrade. I have been noticing they are so worn out, thin so you’d sit in a dip 😄. Other than that, all was an enjoyable trip. Thanks AA!

I’m impressed that we were on time in Sacramento after having a late departure in Newark and our made it. The staff was friendly and warm.

Cramped seats. FAA should make airlines have more legroom, for even short people complain

5.5 hour delay with no explanation on why, along with no proactive effort to reaccomodate me.

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

Most miserable flight ever. We waited almost 2 hours on the runway because the flight was oversold. American offered $1200 credit. Then there was some nonsense about weight distribution. Ridiculous. No food for 8 plus hours on the flight. I will be writing a letter.

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

Everything you need to know for your flight from Panama City to South Carolina

Information on your arrival and departure airports

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