$638 Find Cheap Flights from Pisa to San Francisco - Compare and Save

Only Economy Class is available on flights from Pisa to San Francisco.

There are currently no nonstop flights available from Pisa to San Francisco. Flights with 1 layover take between 17h 11m and 19h 12m in total, depending on the connection.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Round-trip flights from Pisa to San Francisco range from $657 to $975, with an average of $843 over the past 12 months. Anything below $657 counts as a good deal.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $775 to $1,653. That means the highest observed fare was about 2x higher than the lowest one.

One-way fares from Pisa to San Francisco are currently higher than usual. Average one-way flight prices are about $2,865, which is 422% above the typical average for this route.

San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates averaging $63 for economy cars. Top options include:

• Europcar
• Thrifty
• Dollar
• Hertz
• Fox

Flights from Pisa to San Francisco usually depart from Pisa Gal Galilei (PSA) and arrive at San Francisco (SFO).

One-stop flights from Pisa to San Francisco most commonly connect through:

• London Heathrow (LHR) - 33% of one-stop connections
• Kastrup Copenhagen (CPH) - 22% of one-stop connections
• Dublin (DUB) - 22% of one-stop connections
• Frankfurt am Main (FRA) - 22% of one-stop connections

Yes. Flexible dates can save you up to 60% on flights from Pisa to San Francisco. Thursday is the cheapest departure day at $657 round-trip on average, while Wednesday is the most expensive at $1,641, a difference of $984.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Flying via London Heathrow (LHR) gives the shortest average 1-stop total travel time at 17h 11m, compared with 17h 16m via Dublin (DUB) and 18h 31m via Frankfurt am Main (FRA).

San Francisco is 9 hours behind Pisa (Pacific Time vs Central European Time). Plan for the time shift when scheduling connections or first-day activities.

Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.