PGV - TYS

$170 Find Cheap Flights from Greenville to Knoxville - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$467
Typical prices: $582-$671
American Airlines
Mon 10/22Fri 10/26
PGV - TYS • 1 stop
Cheapest one-way
$170
Typical prices: $298-$298
American Airlines
Sun 11/25
PGV - TYS • 1 stop
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Booking Insights
Flight Deals

Cheap Flights from Greenville to Knoxville (PGV-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Knoxville

Thu, Oct 22 - Mon, Oct 26
American Airlines Logo
5:58 pm - 9:49 pmPGV  Pitt-Greenville-TYS Knoxville McGhee Tyson
3h 51m1 stop Charlotte Douglas
American Airlines Logo
6:06 pm - 11:56 pmTYS  Knoxville McGhee Tyson-PGV Pitt-Greenville
5h 50m1 stop Charlotte Douglas
$467American Airlines
Fri, Jan 15 - Sun, Jan 17
American Airlines Logo
12:19 pm - 6:42 pmPGV  Pitt-Greenville-TYS Knoxville McGhee Tyson
6h 23m1 stop Charlotte Douglas
American Airlines Logo
12:30 pm - 4:46 pmTYS  Knoxville McGhee Tyson-PGV Pitt-Greenville
4h 16m1 stop Charlotte Douglas
$582American Airlines
Fri, Oct 23 - Tue, Oct 27
American Airlines Logo
5:58 pm - 11:55 pmPGV  Pitt-Greenville-TYS Knoxville McGhee Tyson
5h 57m1 stop Charlotte Douglas
American Airlines Logo
10:10 am - 3:44 pmTYS  Knoxville McGhee Tyson-PGV Pitt-Greenville
5h 34m1 stop Charlotte Douglas
$597American Airlines
Fri, Oct 23 - Tue, Oct 27
American Airlines Logo
5:58 pm - 11:55 pmPGV  Pitt-Greenville-TYS Knoxville McGhee Tyson
5h 57m1 stop Charlotte Douglas
American Airlines Logo
6:00 am - 3:44 pmTYS  Knoxville McGhee Tyson-PGV Pitt-Greenville
9h 44m2 stops Miami Charlotte Douglas
$682American Airlines
Fri, Jan 15 - Sun, Jan 17
American Airlines Logo
12:19 pm - 11:59 pmPGV  Pitt-Greenville-TYS Knoxville McGhee Tyson
11h 40m2 stops Charlotte Douglas Miami
American Airlines Logo
12:30 pm - 4:46 pmTYS  Knoxville McGhee Tyson-PGV Pitt-Greenville
4h 16m1 stop Charlotte Douglas
$796American Airlines
Fri, Jan 15 - Sun, Jan 17
American Airlines Logo
12:19 pm - 12:28 amPGV  Pitt-Greenville-TYS Knoxville McGhee Tyson
12h 09m2 stops Charlotte Douglas Chicago O'Hare Intl
American Airlines Logo
8:51 pm - 11:53 amTYS  Knoxville McGhee Tyson-PGV Pitt-Greenville
15h 02m2 stops Chicago O'Hare Intl Charlotte Douglas
$973American Airlines
Thu, Oct 22 - Mon, Oct 26
American Airlines Logo
5:05 am - 5:33 pmPGV  Pitt-Greenville-TYS Knoxville McGhee Tyson
12h 28m2 stops Charlotte Douglas Washington, D.C. Reagan-National
American Airlines Logo
6:06 pm - 11:56 pmTYS  Knoxville McGhee Tyson-PGV Pitt-Greenville
5h 50m1 stop Charlotte Douglas
$1,035American Airlines
Fri, Oct 23 - Tue, Oct 27
American Airlines Logo
10:57 am - 6:20 pmPGV  Pitt-Greenville-TYS Knoxville McGhee Tyson
7h 23m2 stops Charlotte Douglas Chicago O'Hare Intl
American Airlines Logo
6:00 am - 3:44 pmTYS  Knoxville McGhee Tyson-PGV Pitt-Greenville
9h 44m2 stops Miami Charlotte Douglas
$1,100American Airlines
Thu, Oct 22 - Mon, Oct 26
American Airlines Logo
5:05 am - 5:33 pmPGV  Pitt-Greenville-TYS Knoxville McGhee Tyson
12h 28m2 stops Charlotte Douglas Washington, D.C. Reagan-National
American Airlines Logo
6:00 am - 5:33 pmTYS  Knoxville McGhee Tyson-PGV Pitt-Greenville
11h 33m2 stops Philadelphia Charlotte Douglas
$1,169American Airlines
Booking Insights

Price, demand and travel trends for Greenville to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Greenville to Knoxville?

Round-trip flights from Greenville to Knoxville typically range from $582 to $671. The lowest price found in the past 5 days was $467, on American Airlines.

Key details for Greenville to Knoxville flights

Cheapest flight

$170
One-way flight from Greenville to Knoxville

When to book flights from Greenville to Knoxville

Are your dates flexible? Find out the best times to travel from Greenville to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Greenville to Knoxville flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Greenville to Knoxville?

    Only Economy Class is available on flights from Greenville to Knoxville.

  • Do I need a passport to fly from Greenville to Knoxville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • Have flight prices from Greenville to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $467 to $1,169. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Greenville to Knoxville looking right now?

    One-way fares from Greenville to Knoxville are currently higher than usual. Average one-way flight prices are about $424, which is 42% above the typical average for this route.

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:

    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Thrifty
    • Avis

  • Which airports can I use when flying from Greenville to Knoxville?

    Flights from Greenville to Knoxville usually depart from Pitt-Greenville (PGV) and arrive at Knoxville McGhee Tyson (TYS).

  • Which airports do connecting flights from Greenville to Knoxville pass through?

    Most connecting flights from Greenville to Knoxville pass through Charlotte Douglas (CLT), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from Greenville to Knoxville?

    Yes. Flexible dates can save you up to 14% on flights from Greenville to Knoxville. Tuesday is the cheapest departure day at $582 round-trip on average, while Friday is the most expensive at $671, a difference of $89.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Your guide to booking Greenville to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Friday. On this route, Tuesday flights average $582, about $89 less than Friday fares (13% savings) based on the last 12 months.

More options for your flight from Greenville to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental