PGV - SFO

$475 Find Cheap Flights from Greenville to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to San Francisco departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to San Francisco, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$533
American Airlines
Wed 10/15Sun 10/19
PGV - SFO • 1 stop
Cheapest one-way
$475
American Airlines
Wed 3/11
PGV - SFO • 1 stop
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Greenville to San Francisco (PGV-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to San Francisco

Wed, Oct 15 - Sun, Oct 19
American Airlines Logo
3:47 pm - 8:44 pmPGV-SFO
7h 57m1 stop
American Airlines Logo
10:15 pm - 10:34 amSFO-PGV
9h 19m1 stop
$533American Airlines
Find Deal
Thu, Oct 16 - Mon, Oct 20
American Airlines Logo
3:09 pm - 9:51 pmPGV-SFO
9h 42m1 stop
American Airlines Logo
1:31 pm - 12:13 amSFO-PGV
7h 42m1 stop
$537American Airlines
Find Deal
Fri, Oct 17 - Mon, Oct 20
American Airlines Logo
5:00 am - 12:31 pmPGV-SFO
10h 31m1 stop
American Airlines Logo
12:50 am - 3:38 pmSFO-PGV
11h 48m2 stops
$538American Airlines
Find Deal
Thu, Oct 16 - Mon, Oct 20
American Airlines Logo
3:09 pm - 8:30 pmPGV-SFO
8h 21m1 stop
American Airlines Logo
11:58 pm - 3:38 pmSFO-PGV
12h 40m2 stops
$542American Airlines
Find Deal
Wed, Oct 15 - Sun, Oct 19
American Airlines Logo
12:26 pm - 9:43 pmPGV-SFO
12h 17m2 stops
American Airlines Logo
7:39 pm - 10:34 amSFO-PGV
11h 55m2 stops
$543American Airlines
Find Deal
Thu, Oct 16 - Mon, Oct 20
American Airlines Logo
3:09 pm - 10:45 pmPGV-SFO
10h 36m2 stops
American Airlines Logo
9:16 am - 12:13 amSFO-PGV
11h 57m2 stops
$547American Airlines
Find Deal
Mon, Mar 16 - Thu, Apr 2
American Airlines Logo
3:55 pm - 8:50 pmPGV-SFO
7h 55m1 stop
American Airlines Logo
12:25 am - 10:22 amSFO-PGV
6h 57m1 stop
$598American Airlines
Find Deal
Mon, Mar 16 - Thu, Apr 2
American Airlines Logo
3:55 pm - 12:04 amPGV-SFO
11h 09m2 stops
American Airlines Logo
12:25 am - 10:22 amSFO-PGV
6h 57m1 stop
$603American Airlines
Find Deal
Mon, Mar 16 - Fri, Apr 3
American Airlines Logo
3:55 pm - 11:02 pmPGV-SFO
10h 07m1 stop
American Airlines Logo
10:40 pm - 10:22 amSFO-PGV
8h 42m1 stop
$663American Airlines
Find Deal
Fri, Oct 17 - Tue, Oct 21
American Airlines Logo
10:59 am - 6:43 pmPGV-SFO
10h 44m2 stops
American Airlines Logo
9:00 am - 11:10 pmSFO-PGV
11h 10m2 stops
$669American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Greenville to San Francisco flights

Get data-powered insights and trends into flights from Greenville to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Greenville to San Francisco?

The average price of all round-trip flights from Greenville to San Francisco clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Greenville to San Francisco, look for departures on Saturdays and avoid leaving on a Friday, as it's usually the priciest day. When flying back from San Francisco, Thursday is the cheapest day to fly and Monday is the most expensive.

Find deals

Good to know

Cheapest flight$475
Flight from Greenville to San Francisco

When to book flights from Greenville to San Francisco

Are your dates flexible? Find out the best times to travel from Greenville to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Greenville to San Francisco

  • What is the cheapest flight from Greenville to San Francisco?

    In the last 3 days, the lowest price for a flight from Greenville to San Francisco was $475 for a one-way ticket and $533 for a round-trip.

  • Do I need a passport to fly between Greenville and San Francisco?

    A passport is not required to fly from Greenville to San Francisco.

  • Which airports will I be using when flying from Greenville to San Francisco?

    Greenville and San Francisco are both served by 1 main airport. You will leave Greenville from Pitt-Greenville and will be arriving at San Francisco.

  • Which aircraft models fly most regularly from Greenville to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Greenville to San Francisco?

    oneworld is the only airline alliance operating flights between Greenville and San Francisco.

  • How does KAYAK find such low prices on flights from Greenville to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Greenville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Greenville with another airline. Booking your flights between Greenville and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Greenville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Greenville to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Greenville to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Greenville to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11033 reviews
7.2Comfort
8.0Crew
6.4Food
7.5Boarding
6.9Entertainment
Airline reviews

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

2.0 MediocreKelly, Sep 2025LIH - LAX
Read more American Airlines reviews

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

There is no room, no gluten free options, or any free internet/entertainment. You have to bring your own tablet or smartphone because there are no screens.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

I flew Business Class. Rory, one of the Cabin stewards, was attentive, explained the menu, provided appropriate drinks. was

Everything you need to know for your flight from Greenville to San Francisco

Information on your arrival and departure airports

Greenville (PGV)
San Francisco (SFO)

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.