$119 Find Cheap Flights from Pittsburgh to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Pittsburgh to South America departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy, 0 bags

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Cheap Flights from Pittsburgh to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$310
Bogotá
Bogotá1 stop$283
Sao Paulo
Sao Paulo2 stops$664
Santiago
Santiago2 stops$664
Cartagena
Cartagena1 stop$216
Quito
Quito2 stops$484
Guayaquil
Guayaquil1 stop$343
Cali
Cali1 stop$348
Cusco
Cusco2 stops$453
Montevideo
Montevideo2 stops$930
Barranquilla
Barranquilla1 stop$323
Santa Marta
Santa Marta2 stops$751
Lima
Lima1 stop$310
Bogotá
Bogotá1 stop$283
Sao Paulo
Sao Paulo2 stops$664
Santiago
Santiago2 stops$664
Cartagena
Cartagena1 stop$216
Quito
Quito2 stops$484
Guayaquil
Guayaquil1 stop$343
Cali
Cali1 stop$348
Cusco
Cusco2 stops$453
Montevideo
Montevideo2 stops$930
Barranquilla
Barranquilla1 stop$323
Santa Marta
Santa Marta2 stops$751

Book Cheap Pittsburgh to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Pittsburgh to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Pittsburgh to South America

Wed, Jan 28 - Wed, Feb 4
Spirit Airlines Logo
6:00 am - 1:15 pm
PIT
-
CTG
7h 15m1 stop
Spirit Airlines Logo
2:21 pm - 11:44 pm
CTG
-
PIT
9h 23m1 stop
$216Spirit Airlines
Sat, Jan 17 - Sat, Jan 24
Spirit Airlines Logo
5:50 pm - 1:15 pm
PIT
-
CTG
19h 25m1 stop
Spirit Airlines Logo
2:21 pm - 11:44 pm
CTG
-
PIT
9h 23m1 stop
$269Spirit Airlines
Fri, Jan 16 - Sat, Jan 24
American Airlines Logo
7:04 pm - 3:30 pm
PIT
-
CTG
20h 26m2 stops
American Airlines Logo
4:30 pm - 12:23 pm
CTG
-
PIT
19h 53m2 stops
$291American Airlines
Wed, Jan 28 - Wed, Feb 4
American Airlines Logo
6:00 am - 3:30 pm
PIT
-
CTG
9h 30m1 stop
American Airlines Logo
2:30 pm - 9:33 am
CTG
-
PIT
19h 03m2 stops
$292American Airlines
Mon, Feb 2 - Fri, Feb 6
United Airlines Logo
8:10 pm - 10:05 pm
PIT
-
MDE
25h 55m2 stops
United Airlines Logo
10:45 am - 9:28 am
MDE
-
PIT
22h 43m2 stops
$308United Airlines
Mon, Feb 2 - Fri, Feb 6
United Airlines Logo
4:38 pm - 10:05 pm
PIT
-
MDE
29h 27m1 stop
United Airlines Logo
10:45 am - 1:10 pm
MDE
-
PIT
26h 25m2 stops
$315United Airlines
Tue, May 5 - Tue, May 12
LATAM Airlines Logo
7:00 am - 4:25 pm
PIT
-
BOG
10h 25m2 stops
LATAM Airlines Logo
11:00 am - 12:24 am
BOG
-
PIT
12h 24m2 stops
$449LATAM Airlines
Mon, Feb 2 - Wed, Mar 4
Delta Logo
1:41 pm - 9:35 pm
PIT
-
UIO
7h 54m1 stop
Delta Logo
11:45 pm - 12:36 pm
UIO
-
PIT
12h 51m1 stop
$564Delta
Mon, Feb 2 - Thu, Mar 5
Delta Logo
1:41 pm - 5:17 am
PIT
-
UIO
15h 36m2 stops
Delta Logo
11:45 pm - 3:56 pm
UIO
-
PIT
16h 11m1 stop
$569Delta
Mon, Mar 9 - Wed, Mar 18
LATAM Airlines Logo
11:30 am - 5:55 am
PIT
-
SCL
17h 25m1 stop
LATAM Airlines Logo
10:30 pm - 11:42 am
SCL
-
PIT
14h 12m1 stop
$714LATAM Airlines
Booking Insights

KAYAK's insights & trends for Pittsburgh to South America flights

Get data-powered insights and trends into flights from Pittsburgh to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Pittsburgh to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Pittsburgh to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Pittsburgh to South America is September, when tickets cost $634 (return) on average. On the other hand, the most expensive months are August and May, when the average cost of round-trip tickets is $947 and $833 respectively.

What’s the cheapest day of the week to fly from Pittsburgh to South America?

The average price of all round-trip flights from Pittsburgh to South America clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to South America on a Monday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from Pittsburgh to South America. For your return ticket, we recommend flying on a Tuesday and avoiding Sundays for the best deals.

How far in advance should I book a flight from Pittsburgh to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Pittsburgh to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Pittsburgh to South America, you should book around 2 weeks before departure, which saves you about 22% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$119
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 21% increase in price.
Flight from Pittsburgh to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Pittsburgh to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Pittsburgh to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Pittsburgh to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Pittsburgh to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Pittsburgh to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Pittsburgh to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Pittsburgh to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Pittsburgh to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally at night, when round-trip flights cost $635 on average. Morning departures are around 9% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $796.

Reviews of the top 5 airlines serving from Pittsburgh to South America

 
Need help choosing which airline to fly with from Pittsburgh to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8010 reviews
8.1Boarding
7.9Entertainment
8.5Crew
7.9Comfort
7.3Food
Airline reviews

None of the airplane features were available during the flight.

4.0 OkayAnonymous, Dec 2025
JFK - SDQ
Read more Delta reviews

None of the airplane features were available during the flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

The flight was on time. I generally don’t drink or eat on short flights and the seats were good and the flight attendants were friendly. That’s all I expect

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

Not great experience - we were super late boarding due to issues with aircraft. Then when we finally all got onboard and seated and they started taxiing out to the runway they just stopped then turned around and went back to the airport. Apparently the crew “ran out of time” to legally fly us. They mentioned that they were about 2 minutes away from taking off. I understand the rules and safety but kinda wonder why they would have bothered boarding us in the first place? Had to go all the way back and de plane and then wait in a HUGE line to get a hotel (this is somewhere around 2:30am) finally got to hotel by Uber (no shuttle after 20min so gave up) and they ended up putting us all back on the same aircraft at 10am next morning so got about 2.5 hours sleep. They did give us. $250 credit, but it was a São Paulo Brazil flight out of Dulles. The flight and everything was fine.

United overall experience is great these days. Airport experience was very organized. Staff on flight were great. App and information as good as it gets.

United have really come back. Airport and boarding process is clear and good, app and information also very good

They charged a fee for 1st bag checked. Others in same party were free.

Flight was delayed 8 times. We were sitting at the airport for 14 hours. We got 2 hours of sleep (if that) on what was not meant to be a red-eye.

The movies offered were great. Staff were very pleasant and very efficient.

After a delay at the gate, C3, at Ohare on Sunday, I left my Blk ski coat on the bench at the gate, lost! Please review my lob claim, thx.

Very bad! They kept delaying my flight and wouldn’t do anything about it

Not comparable to Qatar Airways services on flights to Doha. Flight attendants provided basic services; I was never recognized by name or as an Executive Platinum member. Restrooms were not kept clean during the flight.

Delays to take off and to leave the plane after landing added a lot of time to this flight.

The Phildalphia to Allentown portion was a BUS, not a plane. All was as expected.

Excellent - explanations were clear staff was nice and flight was comfortable

Airport in MXP is crazy. Get there at least 2 hours before flight.

Flight was delayed not sure why no explanation given and no apologies either. Otherwise the flight was fine

Did not get the seat I selected and paid for.

The flight was canceled 3 hours after original take off time

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

Flight was delayed and after being in the airport for like seven hours, it was canceled.

We had to sit and wait for almost an hour after landing and taxiing to the gate. The jet bridge was broken so we just waited and waited and waited and it was inconvenient, hot, and unnecessary.

Flight was in time, very smooth ride and surprisingly lots of legroom in the cabin so I certainly will fly with spirit again

The seats are the most uncomfortable seats I’ve ever sat in. Don’t believe I’ll ever fly spirit again!!

Flight was canceled and instead of rescheduling at the gate we had to go out to the ticket counter. Unruly kids kicking the back of my rows chair with staff to inattentive to say something.

Customer feedback I sent to Spirited today: “I will never fly Spirit Airlines again and will work hard to convince my friends and family to boycott/avoid Spirit Airlines at all costs. I booked three seats for me and my 8 and 10 year old children on NK 1222 from Orlando to Kansas City for 12/7/25 leaving Orlando at 10:37AM. This itinerary was abandoned by Spirit and we were rebooked onto Spirit flight NK 213 leaving at 9:06PM without any notice. Then the nightmare really began. Flight 213 was delayed a total of 12 times, finally leaving at 6:35AM the following day. The gate was changed 5 times and our electronic boarding passes were invalidated at midnight. The worst part was that the 12 separate delays were incremental making it impossible to plan for accommodations for my family. My kids missed a day of school and barely slept under the harsh lights with lots of noise on the filthy airport floor. The customer service agent at Spirit Airlines told us we would be emailed a voucher for a hotel which never happened. I asked about it multiple times and it never arrived in my email inbox. This whole unfortunate situation could’ve been avoided if spirit had taken a realistic approach and delayed the flight from 9 PM until 6 AM from the beginning. My son gleefully deleted the Spirit app from my phone once we landed and we will never fly with Spirit again.”

Honestly horrible. The plane on the way back was delayed 6 times with no explanation on why. When I asked for a refund or some money back because I had to miss a day of work because of the desk, they told me no. Because of how poorly it was handled I will most likely never take spirit again

I love a flight without turbulence and you guys deliver It’d be nice to have comfier seats and maybe some inflight entertainment and snacks but that’s for Delta

30 minute delay, Also there was a medical emergency on the flight. The flight crew was on top of the situation and assisted the medical professionals that happened to be on the flight.

This was my first time on a budget airline and I couldn't even sit down all the way because my knees would embed in the seat in front of me. I'm only 6' tall with a 32" inseam. There's no upside other than y'all are cheap. I'm glad it was only a 2 hour flight. Lesson learned! I get why everybody talks down on budget airlines. The staff was outstanding, the flight went as well as possible, great pilot, great boarding, smooth sailing. Zero chance I'll be back though.

Everything was smoothly and convenient! Just stay in this way!

Everything you need to know for your flight to South America

Information on your arrival and departure airports