ROM - SCL

$591 Find Cheap Flights from Rome to Santiago - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Rome to Santiago departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$819
Typical prices: $833-$1,239
Delta
Tue 11/10Wed 11/25
FCO - SCL • 1 stop
Cheapest one-way
$591
Typical prices: $816-$1,121
Multiple Airlines
Wed 9/23
FCO - SCL • 3 stops
Top airlines
Delta
Cheapest • from $819 (round-trip)
LATAM Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Rome and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Atlanta (ATL)
Cheapest • Avg $825 (round-trip)
Paris (CDG)
Shortest trip • 17h 35m (one-way)
Insights
Insights
Insights
Insights
When to travel
November
Cheapest • 17% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Rome to Santiago (ROM-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Rome to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Rome to Santiago

Tue, Nov 10 - Wed, Nov 25
Delta Logo
1:30 pm - 7:40 am
FCO
-
SCL
22h 10m
1 stop
Delta Logo
11:10 pm - 8:15 am
SCL
-
FCO
29h 05m
1 stop
$819Delta
Thu, Jan 14 - Mon, Mar 15
Delta Logo
1:30 pm - 7:40 am
FCO
-
SCL
22h 10m
1 stop
Delta Logo
11:10 pm - 11:20 am
SCL
-
FCO
32h 10m
1 stop
$824Delta
Fri, Jan 15 - Mon, Mar 15
Delta Logo
10:55 am - 7:40 am
FCO
-
SCL
24h 45m
2 stops
Delta Logo
11:10 pm - 11:20 am
SCL
-
FCO
32h 10m
1 stop
$825Delta
Sun, Aug 30 - Sun, Sep 6
Delta Logo
1:10 pm - 7:15 am
FCO
-
SCL
24h 05m
1 stop
Delta Logo
8:40 pm - 10:05 am
SCL
-
FCO
32h 25m
2 stops
$827Delta
Mon, Aug 17 - Sun, Aug 23
Delta Logo
1:10 pm - 7:15 am
FCO
-
SCL
24h 05m
1 stop
Delta Logo
8:40 pm - 11:00 am
SCL
-
FCO
32h 20m
2 stops
$828Delta
Mon, Aug 17 - Sun, Aug 23
Delta Logo
1:10 pm - 7:15 am
FCO
-
SCL
24h 05m
1 stop
Delta Logo
8:40 pm - 11:00 am
SCL
-
FCO
32h 20m
2 stops
$836Delta
Thu, Sep 3 - Sat, Sep 19
Delta Logo
10:10 am - 7:15 am
FCO
-
SCL
27h 05m
2 stops
Delta Logo
8:40 pm - 11:00 am
SCL
-
FCO
33h 20m
2 stops
$837Delta
Wed, Nov 11 - Thu, Nov 26
Delta Logo
6:00 am - 7:40 am
FCO
-
SCL
29h 40m
2 stops
Delta Logo
11:10 pm - 8:15 am
SCL
-
FCO
29h 05m
1 stop
$840Delta
Sun, Aug 23 - Sun, Sep 6
Delta Logo
6:05 am - 7:15 am
FCO
-
SCL
31h 10m
2 stops
Delta Logo
8:40 pm - 10:05 am
SCL
-
FCO
32h 25m
2 stops
$841Delta
Mon, Aug 17 - Sun, Aug 23
Delta Logo
9:00 am - 7:15 am
FCO
-
SCL
28h 15m
2 stops
Delta Logo
8:40 pm - 11:00 am
SCL
-
FCO
32h 20m
2 stops
$844Delta
Booking Insights

KAYAK's insights & trends for Rome to Santiago flights

Get data-powered insights and trends into flights from Rome to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Rome to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Rome to Santiago departing in November.

What is the cheapest month to fly from Rome to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Rome to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Rome to Santiago is November, where tickets cost $1,007 (return) on average. On the other hand, the most expensive months are April and July, where the average cost of round-trip tickets is $2,075 and $1,344 respectively.

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Good to know

Low season

June
Best time to beat the crowds with an average 21% drop in price.
Most popular time to fly and prices are also 27% lower on average.

When to book flights from Rome to Santiago

Are your dates flexible? Find out the best times to travel from Rome to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Rome to Santiago

  • What is the cheapest flight from Rome to Santiago?

    In the last 5 days, the lowest price for a flight from Rome to Santiago was $591 for a one-way ticket and $819 for a round-trip.

  • Do I need a passport to fly between Rome and Santiago?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Rome and on arrival in Santiago.

  • Which aircraft models fly most regularly from Rome to Santiago?

    We unfortunately don’t have that data for this specific route.

  • How does KAYAK find such low prices on flights from Rome to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Rome to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Rome to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Rome is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Rome to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Rome with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Rome to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Rome up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Rome to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Rome to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Rome to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1958 reviews
7.0Entertainment
7.3Comfort
8.0Crew
6.7Food
7.5Boarding
Airline reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

10.0 ExcellentSarah, Jan 2026
ANF - SCL
Read more LATAM Airlines reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

The crew was amazing. The best in the last times. Great group of people.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

It’s been some time since I saw the plane and the cabin that old and worn out.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

Terrible They charged me 157$ for excess baggage even though my bags were within the normally accepted limits Flight was late. Service was poor. The snacks were really bad

Everything you need to know for your flight from Rome to Santiago

Information on your arrival and departure airports

Santiago (SCL)