$315 Find Cheap Flights from San Antonio to Panama - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Price, demand and travel trends for San Antonio to Panama flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Are flights from San Antonio to Panama cheaper or more expensive than last year?

Fares from San Antonio to Panama are running about 18% higher than they were around this time last year, averaging $709 round-trip.

What are the cheapest fares from San Antonio to Panama right now?

The cheapest fare from San Antonio to Panama in the last week was $640 round-trip, to Panama City Tocumen Intl (PTY).

What’s the cheapest month to fly from San Antonio to Panama?

February is the cheapest time of year to fly, with average fares of $580. Prices are highest in December, when average flight costs increase to around $803.

When is the best time to book flights from San Antonio to Panama?

Book your flights 23 weeks before your trip. KAYAK data collected over the past 12 months shows that booking in this window can save you around 28% compared to booking last-minute (within 2 weeks of departure).

Which airport in Panama is the cheapest to fly to from San Antonio?

All flights from San Antonio to Panama arrive at Panama City Tocumen Intl (PTY). On average, round-trip fares are around $716.

What’s the cheapest day to fly from San Antonio to Panama?

Thursday tends to be the cheapest day to fly from San Antonio to Panama, while Wednesday is the most expensive. Fares run about 15% higher that day, based on the past 12 months of KAYAK data.

What's the cheapest time of day to fly from San Antonio to Panama?

Data from the past 12 months shows it's cheapest to fly to Panama during the evening with average prices of $617. The afternoon is the most expensive time to fly, with average prices of $814.

Key details for San Antonio to Panama flights

Low season

October

Cheapest flight

$315
Beat the crowds with an average 32% drop in travelers.
The most popular month to fly with an average 72% increase in travelers.
One-way flight from San Antonio to Panama City

Your San Antonio to Panama flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from San Antonio to Panama?

    Fares from San Antonio to Panama are around their usual level right now. A round-trip under $638 is considered a good deal, so it's worth keeping an eye out, or setting a Price Alert to catch price changes.

  • How much should I budget for a flight from San Antonio to Panama?

    Over the past 12 months, round-trip fares from San Antonio to Panama have ranged from $638 to $809.

  • What airlines fly nonstop from San Antonio to Panama?

    Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from San Antonio to Panama. One-stop options include United Airlines and American Airlines.

  • Which cabin classes are available on flights from San Antonio to Panama?

    On flights from San Antonio to Panama you can only book Economy Class.

  • What are some popular landmarks in Panama?

    KAYAK travelers' favorite landmarks in Panama include:

    • ATLAPA Conventions Center
    • Panama Old Cathedral
    • Veneto Casino
    • Ancon Hill

Your guide to booking San Antonio to Panama flights

Get tips on when to book, when to fly and what to know before your trip.
  • If you can plan ahead, the sweet spot for booking your flight is 23 weeks before your trip. KAYAK data shows fares in this window are around 28% lower than last-minute bookings (made within 2 weeks of departure). Not ready to commit? Set a Price Alert and we'll let you know when prices change.
  • If your travel dates are flexible, book your trip for February when flights are typically cheapest and avoid December when prices are at their highest.
  • Flying on Thursday is usually the cheapest. Flights on Wednesday cost about 15% more on average, so being flexible with your travel dates could help you save.
  • Start your trip in Panama City, which is the most popular destination in Panama. From there, it's easy to continue on to other popular destinations such as Bocas del Toro, Río Hato and Boquete.

Reviews of the top airlines flying from San Antonio to Panama

 
Need help choosing which airline to fly with from San Antonio to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1554 reviews
8.1Crew
7.4Comfort
7.8Boarding
7.0Food
6.9Entertainment
Airline reviews

It is not a good experience with Copa Airlines: flight delay, luggage delay, etc.

6.0 GoodAnonymous, Aug 2026
Read more Copa Airlines reviews

It is not a good experience with Copa Airlines: flight delay, luggage delay, etc.

We where skipped for this flight will not head to Panama until tonight..

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

Just having a little bit more legroom would've been nice.

Awful. Delayed flights, missed connection to Toronto. Hotel vouchers were for already booked hotels x3. Giant waste of my time

The entertainment is a bit limited, it would be better if they added some games to play besides the movies and tv shows. But the seats are comfortable and the crew is polite

The pilot had to extend the flight time from san antonio to Houston to burn off fuel. This caused a lot of unnecessary stress since we had a tight connection to Aruba. And with no other flights going to Aruba we were worried about spending a night in Houston. We had to to run to our connection because of the flight crews mistake. Not happy.

Fine. The issues I had were associated with luggage being delayed from Turkey to Tanzania

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

Flight was good and crew was super polite. However, there were around 5 kids screaming the WHOLE 2 hours. I understand kids have to come but parents need to do something to control their children. They make the experience terrible, especially after finishing 16 hour shifts at the hospital I needed some sleep, which I did not get.

Gate agent did not hold flight for connection, provided no assistance to get new flight

Nothing they cancelled my connection and couldn't get me on a flight for 3 more days

The plane was dirty and the in seat air wasn't blowing as planes usually do.

More options for your flight from San Antonio to Panama

Complete your trip to Panama with a hotel stay or car rental