$308 Find Cheap Flights from San Antonio to Panama - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Antonio to Panama departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap San Antonio to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Antonio to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Antonio to Panama

Tue, Sep 1 - Thu, Sep 10
United Airlines Logo
7:35 am - 6:37 pm
SAT
-
PTY
11h 02m
1 stop
United Airlines Logo
3:30 pm - 5:44 pm
PTY
-
SAT
26h 14m
1 stop
$632United Airlines
Mon, Aug 17 - Thu, Aug 20
Delta Logo
5:20 am - 12:55 pm
SAT
-
PTY
7h 35m
1 stop
Delta Logo
2:20 pm - 12:28 am
PTY
-
SAT
10h 08m
1 stop
$641Delta
Tue, Sep 1 - Thu, Sep 10
United Airlines Logo
7:35 am - 6:37 pm
SAT
-
PTY
11h 02m
1 stop
United Airlines Logo
3:30 pm - 5:44 pm
PTY
-
SAT
26h 14m
1 stop
$642United Airlines
Thu, Dec 3 - Wed, Dec 9
American Airlines Logo
5:52 pm - 1:48 pm
SAT
-
PTY
18h 56m
2 stops
American Airlines Logo
2:50 pm - 11:59 pm
PTY
-
SAT
10h 09m
1 stop
$645American Airlines
Sun, Aug 9 - Thu, Feb 25
United Airlines Logo
9:37 am - 2:14 pm
SAT
-
PTY
28h 37m
1 stop
United Airlines Logo
8:55 am - 5:33 pm
PTY
-
SAT
9h 38m
1 stop
$648United Airlines
Sun, Jul 26 - Thu, Feb 25
United Airlines Logo
5:30 am - 4:12 pm
SAT
-
PTY
10h 42m
1 stop
United Airlines Logo
8:55 am - 5:33 pm
PTY
-
SAT
9h 38m
1 stop
$649United Airlines
Tue, Nov 17 - Tue, Nov 24
United Airlines Logo
7:30 am - 2:45 pm
SAT
-
PTY
6h 15m
1 stop
United Airlines Logo
8:55 am - 9:13 pm
PTY
-
SAT
13h 18m
1 stop
$651United Airlines
Sun, Aug 16 - Thu, Aug 20
Delta Logo
6:25 am - 12:55 pm
SAT
-
PTY
30h 30m
1 stop
Delta Logo
2:20 pm - 12:28 am
PTY
-
SAT
10h 08m
1 stop
$652Delta
Sun, Jul 26 - Thu, Feb 25
American Airlines Logo
5:47 pm - 12:14 pm
SAT
-
PTY
18h 27m
2 stops
American Airlines Logo
2:39 pm - 11:26 pm
PTY
-
SAT
9h 47m
1 stop
$653American Airlines
Mon, Aug 3 - Thu, Feb 25
American Airlines Logo
5:01 am - 12:14 pm
SAT
-
PTY
7h 13m
1 stop
American Airlines Logo
2:39 pm - 11:26 pm
PTY
-
SAT
9h 47m
1 stop
$654American Airlines
Booking Insights

KAYAK's insights & trends for San Antonio to Panama flights

Get data-powered insights and trends into flights from San Antonio to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from San Antonio to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Antonio to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Antonio to Panama is February, when tickets cost $237 (return) on average. On the other hand, the most expensive months are August and July, when the average cost of round-trip tickets is $579 and $578 respectively.

How far in advance should I book a flight from San Antonio to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Antonio to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Antonio to Panama, you should book around 7 weeks before departure, which saves you about 18% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$308
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 12% increase in price.
Flight from San Antonio to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from San Antonio to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Antonio to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Antonio to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Antonio to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Antonio to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Antonio to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Antonio to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Antonio to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from San Antonio to Panama

 
Need help choosing which airline to fly with from San Antonio to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1567 reviews
7.4Comfort
6.9Food
7.8Boarding
8.1Crew
6.8Entertainment
Airline reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

6.0 GoodAnonymous, May 2026
SCL - PTY
Read more Copa Airlines reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

They delayed the flight 3 hours because it wasn't full they moved us to 5 different gates probably the worst airline ever not even spirit is this bad.

The entertainment is a bit limited, it would be better if they added some games to play besides the movies and tv shows. But the seats are comfortable and the crew is polite

Flight cancelled instead of leaving Friday am now, maybe, leaving Sunday

The pilot had to extend the flight time from san antonio to Houston to burn off fuel. This caused a lot of unnecessary stress since we had a tight connection to Aruba. And with no other flights going to Aruba we were worried about spending a night in Houston. We had to to run to our connection because of the flight crews mistake. Not happy.

one of the flight attendants on the Dallas to frankfurt leg was somewhat rude..

Packed flight, which makes it tough on crew and boarding staff (and the customers of course). But this was great boarding, clear instructions, etc. Traveling on the weekends are always fraught with danger as you have families and less frequent flyers thus more confusion. But this flight went as planned.

Boarded early, left early, arrived 40 mins early! A win win for me!

I felt scammed. The priced advertised was different than what I paid. I paid the whole some online. I then got a call 20 minutes later saying I need to paid 70 more person. She said the price online is not the guaranteed price.

MY FAMILY'S LUGGAGE WAS LOST FROM ROME TO BARI. I WAS THE ONLY ONE THAT RECEIVED MY LUGGAGE FROM ROME TO BARI. AFTER DEPLANING IN BARI, WE WASTED A LOT OF TIME AT BAG CLAIMS LOST AND FOUND REPORTING THE CLAIM AND PLEADING FOR THE BAGS TO BE DELIVERED THE NEXT DAY. WE WERE TOLD THAT IT TAKES 3 DAYS MINIMUM TO DELIVER. MY DAUGHTER AND MY GIRLFRIEND NEEDED THEIR PERSONAL THINGS AND WE WERE STAYING 3 HOURS AWAY FROM THE BARI AIRPORT. WE HAD TO DRIVE 3 HOURS TO THE AIRPORT TO COLLECT OUR LOST LUGGAGE THE NEXT DAY. WE ARE NOT HAPPY WITH THE EXPERIENCE

We had a delay, but thankfully I made it to my connection. Overall it went smooth

Everything you need to know for your flight from San Antonio to Panama

Information on your arrival and departure airports