$253 Find Cheap Flights from San Antonio to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Antonio to Panama departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap San Antonio to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Antonio to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Antonio to Panama

Tue, Sep 1 - Thu, Sep 10
United Airlines Logo
5:30 am - 6:37 pm
SAT
-
PTY
13h 07m
1 stop
United Airlines Logo
10:00 am - 7:53 pm
PTY
-
SAT
9h 53m
1 stop
$582United Airlines
Mon, Aug 10 - Mon, Aug 24
Delta Logo
5:30 am - 1:13 pm
SAT
-
PTY
7h 43m
1 stop
Delta Logo
2:28 pm - 12:15 am
PTY
-
SAT
9h 47m
1 stop
$591Delta
Tue, May 5 - Wed, May 27
American Airlines Logo
6:14 pm - 12:46 pm
SAT
-
PTY
18h 32m
2 stops
American Airlines Logo
1:14 pm - 12:45 pm
PTY
-
SAT
23h 31m
2 stops
$595American Airlines
Wed, Jun 24 - Wed, Jul 1
United Airlines Logo
7:35 pm - 2:14 pm
SAT
-
PTY
18h 39m
1 stop
United Airlines Logo
10:00 am - 5:44 pm
PTY
-
SAT
7h 44m
1 stop
$598United Airlines
Tue, Sep 1 - Thu, Sep 10
American Airlines Logo
5:06 am - 2:20 pm
SAT
-
PTY
9h 14m
1 stop
American Airlines Logo
3:40 pm - 11:23 pm
PTY
-
SAT
7h 43m
1 stop
$600American Airlines
Tue, Sep 1 - Thu, Sep 10
American Airlines Logo
6:07 pm - 2:20 pm
SAT
-
PTY
20h 13m
1 stop
American Airlines Logo
3:40 pm - 10:32 am
PTY
-
SAT
18h 52m
1 stop
$601American Airlines
Sun, Aug 9 - Tue, Aug 25
Delta Logo
10:45 am - 1:13 pm
SAT
-
PTY
26h 28m
1 stop
Delta Logo
2:28 pm - 12:15 am
PTY
-
SAT
9h 47m
1 stop
$602Delta
Tue, Sep 1 - Thu, Sep 10
American Airlines Logo
5:30 pm - 2:20 pm
SAT
-
PTY
20h 50m
2 stops
American Airlines Logo
3:40 pm - 11:53 am
PTY
-
SAT
20h 13m
2 stops
$605American Airlines
Tue, Sep 1 - Thu, Sep 10
American Airlines Logo
6:24 pm - 2:20 pm
SAT
-
PTY
19h 56m
2 stops
American Airlines Logo
3:40 pm - 11:23 pm
PTY
-
SAT
7h 43m
1 stop
$606American Airlines
Tue, Sep 1 - Thu, Sep 10
American Airlines Logo
8:26 pm - 2:20 pm
SAT
-
PTY
17h 54m
2 stops
American Airlines Logo
3:40 pm - 10:32 am
PTY
-
SAT
18h 52m
1 stop
$608American Airlines
Booking Insights

KAYAK's insights & trends for San Antonio to Panama flights

Get data-powered insights and trends into flights from San Antonio to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from San Antonio to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Antonio to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Antonio to Panama is April, when tickets cost $481 (return) on average. On the other hand, the most expensive months are December and March, when the average cost of round-trip tickets is $803 and $660 respectively.

How far in advance should I book a flight from San Antonio to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Antonio to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Antonio to Panama, you should book around 10 weeks before departure, which saves you about 22% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$253
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly and prices are also 13% lower on average.
Flight from San Antonio to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from San Antonio to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Antonio to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Antonio to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Antonio to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Antonio to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Antonio to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Antonio to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Antonio to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from San Antonio to Panama

 
Need help choosing which airline to fly with from San Antonio to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9450 reviews
6.6Food
7.7Boarding
7.3Comfort
8.1Crew
7.1Entertainment
Airline reviews

Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.

2.0 MediocreAnonymous, Feb 2026
IAH - GUA
Read more United Airlines reviews

Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

The crew made our experience extremely bad. They were rude and didn’t have anything for kids.

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

The power at the seat didn't work and the seat itself was difficult to adjust - this was a business class seat. Flight attendant gave me miles to compensate. The attendant was very professional and on top of his game the entire flight.

Delayed, toilets did not flush, pilot parked to far away from Gate

I like flying first class, and United has a nice one

Unbelievably poor service from flight attendants. They didn’t even do water service on a four hour flight. Just disrespectful.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

Mostly good. The WiFi wasn’t working so that was not great.

I rated the experience "mediocre" because of the 2 hour delay in take off. This is the 4th flight from DFW on AA where there was a delay and in one of the instances (after 13 delays), the flight was cancelled. I understand weather but for the March 18th flight, there was no weather issue in Dallas or Detroit. I called Concierge Key and they were wonderful, booking me on a later flight in case my flight was cancelled. I have flown with American for many years and never has there been this consistent pattern of delays. Very disappointing.

As a first class customer, there was no power the entire flight which limited my ability to work. I find this unacceptable. The first 11 rows on the left side of the plan were out. I was only offered the option to charge my phone which was not the issue because my laptop was out of power. I asked if there was anything that can be done for me, and the answer was, "no". I was not offered any type of compensation for this AA problem which caused me unnecessary stress due to inability to address business issues on an already challenging travel day. Flight attendants tried to reset the power once but that was the extent of their support. Very disappointing for the lack of expected services on a flight. Please contact me with customer focused response to this complaint.

Easy boarding. Rows are smaller but that may be an older and bigger me now :)

Check in was rough because the check in crew did not know how to manage my international visa documents. Required a long process and 4 people to finally be able to proceed to security. They told us incorrect information several times before acknowledging we did indeed have everything we needed from the start.

Poor communication ahead of time about flight delays and old planes/other equipment.

Mechanical issue delayed us 2hrs and then once we landed sat on tarmac for 30mins because someone left a vehicle in front of the gaye

The crew was excellent and overall the flight was good. No complaints.

Like all of the flights I took to get down to Dallas. They were delayed

Forced to check bags. Crew uninterested in collecting trash. Unclean seats.

Everything you need to know for your flight from San Antonio to Panama

Information on your arrival and departure airports