$180 Find Cheap Flights from San Antonio to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Antonio to South America departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from San Antonio to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$595
Bogotá
Bogotá1 stop$453
Santiago
Santiago3 stops$913
Cartagena
Cartagena2 stops$563
Quito
Quito1 stop$637
Guayaquil
Guayaquil1 stop$705
Cali
Cali2 stops$593
Cusco
Cusco3 stops$855
Pereira
Pereira2 stops$627
Barranquilla
Barranquilla1 stop$446
Montevideo
Montevideo2 stops$1,084
Santa Marta
Santa Marta2 stops$735
Asuncion
Asuncion2 stops$1,425
Lima
Lima1 stop$595
Bogotá
Bogotá1 stop$453
Santiago
Santiago3 stops$913
Cartagena
Cartagena2 stops$563
Quito
Quito1 stop$637
Guayaquil
Guayaquil1 stop$705
Cali
Cali2 stops$593
Cusco
Cusco3 stops$855
Pereira
Pereira2 stops$627
Barranquilla
Barranquilla1 stop$446
Montevideo
Montevideo2 stops$1,084
Santa Marta
Santa Marta2 stops$735
Asuncion
Asuncion2 stops$1,425

Book Cheap San Antonio to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Antonio to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Antonio to South America

Mon, Jun 1 - Tue, Jun 30
Viva Logo
8:45 pm - 12:40 am
SAT
-
BOG
27h 55m
1 stop
Viva Logo
1:45 am - 10:50 am
BOG
-
SAT
9h 05m
1 stop
$453Viva
Thu, Sep 3 - Sun, Sep 6
Viva Logo
12:00 pm - 12:40 am
SAT
-
BOG
12h 40m
1 stop
Viva Logo
1:45 am - 7:40 pm
BOG
-
SAT
17h 55m
1 stop
$473Viva
Thu, May 14 - Wed, May 20
Delta Logo
5:25 am - 1:40 pm
SAT
-
BOG
8h 15m
1 stop
Delta Logo
5:15 pm - 5:06 pm
BOG
-
SAT
23h 51m
2 stops
$517Delta
Thu, Jun 11 - Sun, Jun 14
Spirit Airlines Logo
5:26 pm - 12:26 pm
SAT
-
CTG
19h 00m
1 stop
Spirit Airlines Logo
1:31 pm - 4:16 pm
CTG
-
SAT
26h 45m
1 stop
$577Spirit Airlines
Thu, May 14 - Tue, May 19
United Airlines Logo
11:45 am - 5:36 pm
SAT
-
CLO
29h 51m
2 stops
United Airlines Logo
12:06 pm - 8:42 am
CLO
-
SAT
20h 36m
2 stops
$593United Airlines
Tue, Aug 11 - Tue, Aug 25
Delta Logo
5:30 am - 1:13 pm
SAT
-
CTG
7h 43m
1 stop
Delta Logo
2:28 pm - 12:15 am
CTG
-
SAT
9h 47m
1 stop
$593Delta
Sun, May 10 - Thu, May 14
United Airlines Logo
7:35 am - 11:00 pm
SAT
-
CTG
15h 25m
2 stops
United Airlines Logo
3:05 pm - 3:39 pm
CTG
-
SAT
24h 34m
2 stops
$594United Airlines
Tue, May 19 - Wed, May 20
American Airlines Logo
5:25 am - 8:15 pm
SAT
-
MDE
14h 50m
1 stop
American Airlines Logo
11:59 pm - 11:59 pm
MDE
-
SAT
24h 00m
1 stop
$610American Airlines
Sun, Jun 7 - Sun, Jun 14
Spirit Airlines Logo
5:26 pm - 12:26 pm
SAT
-
CTG
19h 00m
1 stop
Spirit Airlines Logo
1:31 pm - 4:16 pm
CTG
-
SAT
26h 45m
1 stop
$610Spirit Airlines
Tue, Aug 11 - Tue, Aug 25
American Airlines Logo
5:15 am - 2:15 pm
SAT
-
CTG
9h 00m
1 stop
American Airlines Logo
3:15 pm - 10:09 am
CTG
-
SAT
18h 54m
2 stops
$612American Airlines
Booking Insights

KAYAK's insights & trends for San Antonio to South America flights

Get data-powered insights and trends into flights from San Antonio to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from San Antonio to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Antonio to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Antonio to South America is March, when tickets cost $542 (return) on average. On the other hand, the most expensive months are October and November, when the average cost of round-trip tickets is $849 and $789 respectively.

How far in advance should I book a flight from San Antonio to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Antonio to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Antonio to South America, you should book around 5 weeks before departure, which saves you about 20% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$169
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 13% increase in price.
Flight from San Antonio to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from San Antonio to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Antonio to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Antonio to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Antonio to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Antonio to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Antonio to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Antonio to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Antonio to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from San Antonio to South America

 
Need help choosing which airline to fly with from San Antonio to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8439 reviews
7.2Food
7.8Entertainment
8.1Boarding
8.5Crew
7.9Comfort
Airline reviews

Everything was great. The only issue is unfixable. Seats are too small. 😁🤪

10.0 ExcellentAnonymous, Apr 2026
ATL - AMS
Read more Delta reviews

Everything was great. The only issue is unfixable. Seats are too small. 😁🤪

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Crew was nice, meal was good. Entertainment had to be rebooted 3 times and still did not work. Turns out there was residue on screen, it needed to be cleaned to prevent the touchscreen buttons from continuously activating. I had entertainment for the last 45 minutes of a 5 hour 45 minute flight. Really unacceptable for first class. Flight attendent indicated your cleaning solution creates this problem. Seems as if this is widely known, you should be using a different product or cleaning better. Really really disappointing which simply added to the wi fi on your planes with reliably never ever works.

The baggage belt was not updated on the Delta App and was displayed on the wrong belt board. Was not expecting this to happen.

The plan was delayed and left DC 90 minutes late. However, it showed a 20 minute delay on the delta app, then a 12 min delay. It turned out to be an hour delay. I found out where the plane was with flightaware. Stop keeping customers in the dark about what is going on.

Everything went smoothly, although the usual gripes about airline travel were still present: the boarding process is inefficient, the snack selection is limited, and so on. Since there was extra space on the flight, the gate agent rearranged many people's seats to put people on the aisles and windows, leaving the middle seats empty, as much as possible, which was pretty great.

Landed without a gate ready. Plane is extremely old and dirty.

All the amenities was wonderful, if they could keep their prices that low. I'd fly with them all the time.

Very old plane with no inflight entertainment. I purchased the internet pass and it was nearly unusable.

My tray was broken so i had no place to work or eat except my lap. Flight attendant said I would get an email with some credit or miles, it was a complete waste of time as I could only function at about 20% of normal. I have not received anything yet.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

It's a long flight and I would have liked better snacks between lunch and the arrival meal. It's fine to have fruit and nuts but I really don't like ramen because it's salty junk soup. I'd suggest sandwiches. They're not expensive nor are they hard to store for a long flight. The FA's had a couple of big services and they were super busy preparing, executing and then cleaning up. Then they disappeared.

Great flight. Got to watch a movie. Smooth flight and early arrival at ORD.

The wheelchair service is useless. They live you in different spots, not tell you anything just wait. I waited 30 minutes in Frankfurt when decided to walk the 25 minutes distance. In Budapest nobody came.

Fine. The issues I had were associated with luggage being delayed from Turkey to Tanzania

I've been flying American mostly, and it's been very frustrating. This united flight makes me realize maybe the issue isn't flying, but the airline. United was a significantly better experience. The plane was more comfortable, with a normal amount of leg room (vs the ridiculous reductions AA has made), more comfortable seats, screens to watch movies. It was a much better experience!

We had excellent customer service despite the chaos at George Bush airport in Houston!

It isvvery small flight. No leg room . No space to put my personal item at feet.

Didn't make the flight because the first leg of my flight was canceled and the next leg was already booked.

Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.

Overall we had a good experience during our flight from San Francisco to Houston.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

My flight got delayed a total of five times. And the boarding gate changed four times. most of the time the platform was not up-to-date with the changes taking place. The most discouraging part of the entire trip by far.

Returned home with a blood clot from flight homes and the uncomfortable aircraft I was on.

The crew was very kind, but no in-flight entertainment monitors and a 2 hour and 30 minute delay was extremely frustrating.

Everything was delayed and the staff sent me to the wrong gate, causing me to miss one of my flights. I arrived at my destination 6 hours later than I was supposed to.

It was good, the staff was great, and the food, was as usual, tea and biscuit. Bathroom was clean, and the plane was clean as well.

It was really a terrific experience both going and returning on AA. Staff and crew were professional.

I was able to get the AA customer Service desk to put me on an earlier flight without any issues.

The seat was comfortable, the attendants were very nice and WiFi made my life so much easier with work. Kudos!

To have arrived on time and not 3 hours late after having already spent $100 to change to an earlier flight, only to arrive back home close to the original flight time.

The repeated flight delays—this time nearly three hours without any weather-related cause—are unacceptable. Yet, passengers are penalized heavily even for being a minute late. It is unreasonable that there is no compensation for such significant delays, nor even basic provisions like water during the wait or in flight. This imbalance in accountability is deeply frustrating and needs to be addressed.

They didn’t put my luggage on my transfer so I had to spend the night in Detroit. They said my luggage would be here in the morning and they’re still searching for it. It did not arrive apparently.

Great just wish they always had WiFi on every flight couldn’t even purchase it

They keep delaying and cancel at last moment and height was for you to get refund need to be in chat line for two hours. I complained to DOT. Never recommend this airline on Kayak please

We had to take a bus to the plane with a old woman and carry on bags, and at landing at the airport we have to wait one hour seating on the plane waiting for a gate. We came back from Australia Bussines class Quantas 16 hours traveling, then wait in Dallas 7 hours for connection...honestly waiting 1 hour more at the plane was the worst part.

Flight delayed twice (not Spirit fault) No food served* No entertainment * *in response to my choices in the rating. None was provided so couldn’t rate properly

The flight was a big joke very uncomfortable I had a horrible experience and I will never fly with them again everything about the flight was bogus and I’m not happy with it at all this experience makes me not want to fly ever again

Pricing, boarding time communication, over priced baggage and overall service is lacking, seating unconfortable

Horrendous and unprofessional staff and will never fly spirit again

When I arrived at the airport at 4:00 in the morning, I was notified that I "hadn't paid" for my ticket (I had paid and had a boarding pass). Then I was told that while I had paid, the ticket was $600 more than it actually was, and that I needed to pay that so I could board. None of this was true, of course, but it took 20 minutes, two crew members behind the desk, and one on the phone to clear up.

Everything you need to know for your flight to South America

Information on your arrival and departure airports