$124 Find Cheap Flights from San Antonio to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Antonio to South America departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from San Antonio to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$326
Bogotá
Bogotá1 stop$303
Santiago
Santiago2 stops$713
Cartagena
Cartagena1 stop$327
Quito
Quito1 stop$584
Guayaquil
Guayaquil1 stop$325
Cali
Cali2 stops$400
Cusco
Cusco2 stops$581
Pereira
Pereira2 stops$424
Montevideo
Montevideo2 stops$1,178
Barranquilla
Barranquilla2 stops$421
Santa Marta
Santa Marta2 stops$913
Asuncion
Asuncion2 stops$1,251
Lima
Lima1 stop$326
Bogotá
Bogotá1 stop$303
Santiago
Santiago2 stops$713
Cartagena
Cartagena1 stop$327
Quito
Quito1 stop$584
Guayaquil
Guayaquil1 stop$325
Cali
Cali2 stops$400
Cusco
Cusco2 stops$581
Pereira
Pereira2 stops$424
Montevideo
Montevideo2 stops$1,178
Barranquilla
Barranquilla2 stops$421
Santa Marta
Santa Marta2 stops$913
Asuncion
Asuncion2 stops$1,251

Book Cheap San Antonio to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Antonio to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Antonio to South America

Thu, Feb 19 - Wed, Feb 25
Multiple Airlines Logo
1:57 pm - 12:47 pm
SAT
-
BOG
21h 50m1 stop
Multiple Airlines Logo
1:45 pm - 1:12 pm
BOG
-
SAT
24h 27m1 stop
$303Multiple Airlines
Wed, Feb 18 - Sat, Feb 21
Spirit Airlines Logo
10:26 am - 2:10 pm
SAT
-
BOG
26h 44m1 stop
Spirit Airlines Logo
3:06 pm - 9:30 am
BOG
-
SAT
19h 24m1 stop
$306Spirit Airlines
Mon, Jan 26 - Thu, Jan 29
LATAM Airlines Logo
5:20 am - 2:17 pm
SAT
-
CTG
7h 57m1 stop
LATAM Airlines Logo
3:32 pm - 12:38 am
CTG
-
SAT
10h 06m1 stop
$421LATAM Airlines
Thu, Jan 22 - Tue, Jan 27
United Airlines Logo
11:43 am - 11:00 pm
SAT
-
CTG
10h 17m2 stops
United Airlines Logo
9:42 am - 3:31 pm
CTG
-
SAT
30h 49m2 stops
$424United Airlines
Thu, Jan 22 - Tue, Jan 27
American Airlines Logo
5:00 pm - 1:30 pm
SAT
-
CTG
19h 30m2 stops
American Airlines Logo
2:30 pm - 11:59 pm
CTG
-
SAT
10h 29m1 stop
$426American Airlines
Thu, Apr 30 - Mon, May 4
United Airlines Logo
7:34 pm - 11:01 pm
SAT
-
CTG
27h 27m2 stops
United Airlines Logo
9:45 am - 8:42 am
CTG
-
SAT
22h 57m2 stops
$430United Airlines
Thu, Jan 22 - Tue, Jan 27
American Airlines Logo
5:10 pm - 3:30 pm
SAT
-
CTG
21h 20m1 stop
American Airlines Logo
2:30 pm - 11:59 pm
CTG
-
SAT
10h 29m1 stop
$432American Airlines
Mon, Jan 26 - Wed, Jan 28
LATAM Airlines Logo
5:20 am - 2:17 pm
SAT
-
CTG
7h 57m1 stop
LATAM Airlines Logo
4:35 am - 5:22 pm
CTG
-
SAT
13h 47m2 stops
$594LATAM Airlines
Tue, Jan 20 - Sun, Feb 1
Delta Logo
4:29 pm - 3:30 pm
SAT
-
SCL
20h 01m2 stops
Delta Logo
11:10 pm - 8:25 pm
SCL
-
SAT
24h 15m1 stop
$761Delta
Thu, Jan 22 - Sun, Feb 1
Delta Logo
6:30 am - 7:00 am
SAT
-
SCL
21h 30m2 stops
Delta Logo
11:10 pm - 8:25 pm
SCL
-
SAT
24h 15m1 stop
$765Delta
Booking Insights

KAYAK's insights & trends for San Antonio to South America flights

Get data-powered insights and trends into flights from San Antonio to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from San Antonio to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Antonio to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Antonio to South America is March, when tickets cost $678 (return) on average. On the other hand, the most expensive months are June and May, when the average cost of round-trip tickets is $797 and $775 respectively.

How far in advance should I book a flight from San Antonio to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Antonio to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Antonio to South America, you should book around 3 weeks before departure, which saves you about 13% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 20 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$124
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 15% increase in price.
Flight from San Antonio to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from San Antonio to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Antonio to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Antonio to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Antonio to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Antonio to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Antonio to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Antonio to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Antonio to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from San Antonio to South America

 
Need help choosing which airline to fly with from San Antonio to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8030 reviews
8.1Boarding
7.8Entertainment
7.9Comfort
7.2Food
8.5Crew
Airline reviews

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

2.0 MediocreWilliam, Jan 2026
LGA - BOS
Read more Delta reviews

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Flight was late from Newark to Atlanta, I asked flight attendant to please let my family of 3 out first when we landed to Atlanta because we were late for our connecting flight to Quito. She didn't and we were late for 5 minutes we couldn't board the plane and spend hours trying to get another flight with customer service for the next day.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Late delayed flight delays boarding and delays leaving and delays on arrival too. Cramped plane no room no food.

DTW line is too long. The flights from DTW to BWI are always delayed for unknown reasons.

Delta canceled our flight and we had to scramble to find another airline to get home. Phoenix is not a delta hub so they didn’t have another plane. It would have been a red eye though Salt Lake City. Getting in at 5am. No bueno.

This flight was no comparison to our prior flight. I'm thinking it all has to do with the age of the aircraft.

This flight was a first class choice and left much to be desired. Seat backs on seats were falling apart and torn. Seats actually didn't come to a "full & upright position". Pull out table was sprung. Not any significant leg room. All in all we were on an obviously older plane and felt overcharged for what we received as first class.

A 12 hour flight during the day with one real meal service - are you kidding? Also the breakfast was one of the worst and not what was listed

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Unbelievably poor service from flight attendants. They didn’t even do water service on a four hour flight. Just disrespectful.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

Lately I like the planes have been exceptionally filthy. There’s lines of dust and dirt all across the ceiling in the vents, and the cracks in between the seats are literally full of food. It’s definitely not the quality of service that I was used to with United. I’m also very disappointed with the Wi-Fi! All I wanna do is knock out a few work jobs while I’m trapped in my seat And it spools so bad. They did provide me with a refund, but the process of getting that refund is so complicated. It’s unfortunate.

Crew was excellent. This was a relatively long flight though and had very little leg room, and no entertainment.

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

Flight was good and crew was super polite. However, there were around 5 kids screaming the WHOLE 2 hours. I understand kids have to come but parents need to do something to control their children. They make the experience terrible, especially after finishing 16 hour shifts at the hospital I needed some sleep, which I did not get.

Plane was crowded and even when we hit altitude, the plane was hot, not enough air flow.

Flight was delayed and missed my connection Lufthansa didn’t respond.

the delay for 3 hours was understandable due to weather conditions but the flight should’ve provided some on flight compensations or at least provide more food.

United could have one single once of customer service. No human United employee would help me with the invalid mileage plus number, they said I had to speak with the computer.

Good food & refreshment. The seats and entrainment screens are modern compared to others. The staff though pleasant serve and attend to passengers based on nationality. Some get served first others last regardless of their seating positions.

The economy seats are very cramped and the food was bizarre. However, I did like the greek yogurt option for breakfast.

We never made it due to delays on both ends. Gate attendant said it was mechanical but the system said otherwise, so no compensation. That’s not right.

The pilot greased the landing and the crew was fantastic.

Attendants were pleasant and the flight was smooth and relaxed.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

Things were delayed a little. But that didn’t affect my plans. It was fine. I was surprised it was so full thanksgiving day. The crew were friendly and professional.

The flight was delayed multiple times, again no fault of American but again the extra cost, for everything makes it feel like a cheap airline! Especially when flights are outrageously expensive already

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

I have a gluten allergy so did have any food

Sadly there was a crew member very rude with my kid and with me.

They canceled the flight and didn't assist in getting a new flight on any airline. I had to spend 10 hrs in the airport after getting a ticket On Delta for twice as much. I've flown Spirit many times and this was my worst experience I've had.

Late taking off. ATC sent us circling around Chicago for almost an hour, after landing taxied for 40 minutes.

We had too many delays for the crew not the plane

Awful!!! Spirit cancelled my flight just 4 hours before departure- with no alternative flights available. I ended up missing a huge family gathering because I wasn’t able to get out. Such An awful experience. And on top of that, all the buckle and dime-ing for bags. I will never book with Spirit EVER

I'd have like to check my bag and not toss my hair products.sears are very uncomfortable. And that even water isn't free really sucks. The ticket was almost $400

Terrible. They cancelled the flight at the last minute after I had checked in at the airport and then told me they could only put me on a flight after 7 days. Pathetic.

Spirit cancelled the flight very late last night, I was on the way to the airport when I found out

Flight was canceled and instead of rescheduling at the gate we had to go out to the ticket counter. Unruly kids kicking the back of my rows chair with staff to inattentive to say something.

Honestly horrible. The plane on the way back was delayed 6 times with no explanation on why. When I asked for a refund or some money back because I had to miss a day of work because of the desk, they told me no. Because of how poorly it was handled I will most likely never take spirit again

Everything you need to know for your flight to South America

Information on your arrival and departure airports