$161 Find Cheap Flights from San Antonio to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Antonio to South America departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Antonio to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$463
Bogotá
Bogotá1 stop$368
Santiago
Santiago2 stops$778
Cartagena
Cartagena1 stop$388
Quito
Quito1 stop$637
Guayaquil
Guayaquil1 stop$484
Cali
Cali1 stop$441
Cusco
Cusco3 stops$946
Pereira
Pereira2 stops$540
Montevideo
Montevideo2 stops$1,031
Barranquilla
Barranquilla1 stop$478
Santa Marta
Santa Marta3 stops$668
Asuncion
Asuncion3 stops$1,091
Lima
Lima1 stop$463
Bogotá
Bogotá1 stop$368
Santiago
Santiago2 stops$778
Cartagena
Cartagena1 stop$388
Quito
Quito1 stop$637
Guayaquil
Guayaquil1 stop$484
Cali
Cali1 stop$441
Cusco
Cusco3 stops$946
Pereira
Pereira2 stops$540
Montevideo
Montevideo2 stops$1,031
Barranquilla
Barranquilla1 stop$478
Santa Marta
Santa Marta3 stops$668
Asuncion
Asuncion3 stops$1,091

Book Cheap San Antonio to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Antonio to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Antonio to South America

Mon, Apr 20 - Fri, Apr 24
Spirit Airlines Logo
6:00 am - 1:12 pm
SAT
-
BOG
7h 12m
1 stop
Spirit Airlines Logo
2:07 pm - 11:51 pm
BOG
-
SAT
9h 44m
1 stop
$368Spirit Airlines
Thu, Apr 9 - Sun, Apr 12
Spirit Airlines Logo
10:22 am - 12:21 am
SAT
-
MDE
13h 59m
1 stop
Spirit Airlines Logo
1:17 am - 9:27 am
MDE
-
SAT
8h 10m
1 stop
$371Spirit Airlines
Wed, Jul 29 - Fri, Aug 7
American Airlines Logo
5:01 am - 2:38 pm
SAT
-
BAQ
9h 37m
1 stop
American Airlines Logo
1:50 pm - 11:25 pm
BAQ
-
SAT
9h 35m
1 stop
$570American Airlines
Fri, Aug 7 - Fri, Aug 14
American Airlines Logo
2:17 pm - 12:45 pm
SAT
-
BAQ
22h 28m
2 stops
American Airlines Logo
1:50 pm - 9:19 am
BAQ
-
SAT
19h 29m
2 stops
$575American Airlines
Sun, May 10 - Wed, May 13
United Airlines Logo
11:45 am - 11:38 pm
SAT
-
BAQ
11h 53m
2 stops
United Airlines Logo
9:13 am - 7:40 pm
BAQ
-
SAT
34h 27m
2 stops
$588United Airlines
Mon, Jul 27 - Sun, Aug 9
LATAM Airlines Logo
5:30 am - 6:30 pm
SAT
-
BAQ
13h 00m
2 stops
LATAM Airlines Logo
7:20 am - 12:14 am
BAQ
-
SAT
16h 54m
2 stops
$596LATAM Airlines
Thu, Apr 9 - Wed, Apr 15
Delta Logo
6:13 am - 6:59 pm
SAT
-
UIO
12h 46m
1 stop
Delta Logo
12:59 am - 11:21 am
UIO
-
SAT
10h 22m
1 stop
$637Delta
Mon, Apr 13 - Mon, Apr 20
Delta Logo
6:20 am - 4:43 am
SAT
-
UIO
22h 23m
2 stops
Delta Logo
6:50 pm - 12:59 pm
UIO
-
SAT
18h 09m
2 stops
$642Delta
Sat, Sep 5 - Mon, Sep 14
United Airlines Logo
5:57 pm - 5:00 am
SAT
-
UIO
11h 03m
1 stop
United Airlines Logo
7:25 am - 3:39 pm
UIO
-
SAT
8h 14m
1 stop
$647United Airlines
Tue, May 26 - Wed, Jun 24
LATAM Airlines Logo
1:33 pm - 1:10 pm
SAT
-
SDU
21h 37m
2 stops
LATAM Airlines Logo
8:15 pm - 2:42 pm
SDU
-
SAT
20h 27m
2 stops
$1,221LATAM Airlines
Booking Insights

KAYAK's insights & trends for San Antonio to South America flights

Get data-powered insights and trends into flights from San Antonio to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from San Antonio to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Antonio to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Antonio to South America is March, when tickets cost $542 (return) on average. On the other hand, the most expensive months are October and July, when the average cost of round-trip tickets is $849 and $819 respectively.

How far in advance should I book a flight from San Antonio to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Antonio to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Antonio to South America, you should book around 5 weeks before departure, which saves you about 13% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 6 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$161
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly with an average 12% increase in price.
Flight from San Antonio to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from San Antonio to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Antonio to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Antonio to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Antonio to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Antonio to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Antonio to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Antonio to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Antonio to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from San Antonio to South America

 
Need help choosing which airline to fly with from San Antonio to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8292 reviews
7.2Food
7.8Entertainment
7.9Comfort
8.5Crew
8.1Boarding
Airline reviews

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

2.0 MediocreSusan, Mar 2026
JAX - ATL
Read more Delta reviews

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The WiFi was not working. That made for a long flight.

With Aeromexico it ended up good but with Delta it was bad because we did everything through Delta... Showed up at the Delta terminal... It was the wrong place! Nothing ever told us to go to the Aeromexico terminal. It said "in partnership with Aeromexico" but I was never instructed to check in with them or go to their terminal. We had to haul @$$ running through the airport and almost didn't make it thanks to this poor communication. 👎🏽

Absolutely no communication on why there's a delay and multiple flight time reschedules. I would have canceled the flight and drove back home if I known it was going to be rescheduled 3 or 4 times.

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Stop changing gates. Stop cancelling flights Stop moving my seat.

Extremely disappointed with Delta. They canceled flight last minute and then I rebooked the other flights and with which were delayed as well

Could not get my connecting flight boarding pass until four hrs before departure! Ver annoying especially since the staff could not explain why!

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

The flight was late. Please do not delay next time.

Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

The crew made our experience extremely bad. They were rude and didn’t have anything for kids.

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

The power at the seat didn't work and the seat itself was difficult to adjust - this was a business class seat. Flight attendant gave me miles to compensate. The attendant was very professional and on top of his game the entire flight.

Delayed, toilets did not flush, pilot parked to far away from Gate

I like flying first class, and United has a nice one

Unbelievably poor service from flight attendants. They didn’t even do water service on a four hour flight. Just disrespectful.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

Easy boarding. Rows are smaller but that may be an older and bigger me now :)

Check in was rough because the check in crew did not know how to manage my international visa documents. Required a long process and 4 people to finally be able to proceed to security. They told us incorrect information several times before acknowledging we did indeed have everything we needed from the start.

Poor communication ahead of time about flight delays and old planes/other equipment.

Mechanical issue delayed us 2hrs and then once we landed sat on tarmac for 30mins because someone left a vehicle in front of the gaye

The crew was excellent and overall the flight was good. No complaints.

Like all of the flights I took to get down to Dallas. They were delayed

Forced to check bags. Crew uninterested in collecting trash. Unclean seats.

Flight pulled out on time but sat on runway for 30 mins. It was extremely cold in the aircraft despite wearing a winter coat. Surprisingly they had a vegetarian meal but could have some better snack choices for a 8 hour flight.

We had a male flight attendant who was super attentive and wonderful! Very professional. I have both gluten and dairy intolerance, and was only able to get a gluten free part, and not the dairy free part of the meal. Easy to order ahead of time and I appreciate being able to do that.

It was a train wreck but on an airplane. First off, flight was delayed then we board only to hear two announcements, First weather delays in Orlando and second backup battery warning on emergency lights. After sitting on the plane for almost 2 hours they have us deplane due to the maintenance issue. We were told they were getting another plane. In the mean time, I notice another American- Orlando flight and ask the gate agent if I can switch. He says he cant help me and I'd have to walk to A13 from A37. Really!? I get down there and get a seat only to get an announcement my original flight was RE-boarding. The Then inflight there's no communication and I notice on flightaware were circling over the Gulf of America. I call the flight attendant and of course she has no clue and apparently 5m later the pilot finally tells us about another delay. Why does American always have these service and delay issues? They are my LAST choice in flights now!

When I arrived at the airport at 4:00 in the morning, I was notified that I "hadn't paid" for my ticket (I had paid and had a boarding pass). Then I was told that while I had paid, the ticket was $600 more than it actually was, and that I needed to pay that so I could board. None of this was true, of course, but it took 20 minutes, two crew members behind the desk, and one on the phone to clear up.

First off, I had a conversation with a flight attendant that was working this flight. I overheard her telling another flight attendant while we were in line for Chic-Fil-A that the flight was not going to land until 12:47 pm. I found this odd since the flight was to take off at 1:03. I commented to the flight attendant that was going to mess up the on-time take-off She said. if you fly alot you will notice that it's a good thing if the flight even arrives at all. I said that was a low bar. I think that flight attendants represent their airlines whether on board or in the airport ordering food. I was surprised to hear such negativity. However, I have noticed that Spirit flight attendants are usually in a sour mood.. Eventually the flight arrived and I boarded and the flight took off an hour late. There was no direction about the on-board wi-fi. Nor was there any info in the seat back pocket. I don't know if there was wi-fi or not, There were no complimentary snacks or drinks for my row 36 as there was turbulence and the captain asked the flight attendants to stop serving just as they were close to my row. When the turbulence stopped, they did have time to serve us but they did not. Upon arriving, the flight attendant asked anyone not having to catch a flight to Ft. Laudersle which was a tight connection to sit down and let those people pass. I complied but I could not help thinking that if Spirit would have took off on time that they would not have to inconvenience their passengers. All in all, I think Spirit is a mediocre airline at best. There are so many things they could do to improve. Yet, since I only fly Spirit infrequently preferring Southwest and Delta, I like to see if they are improving and sadly no, they are not. One good thing - nice modern seats and interiors.

My flight was cancelled I missed time at work and got a parking ticket

Went as planned. No wifi included and no screens. No free snacks. Didn't buy food so can't rate that. Unable to charge devices on plane. Staff were friendly and flight was fast, cheap and convenient.

I purchased extra legroom so I will be comfortable but the guy behind me is a big guy who keeps on moving and since he is big I can feel his movement at the back of my chair.

Spirit was on time. They maintained updates and information. The crew was friendly and professional. Because this is a budget friendly airline, they have dispensed with a lot of frills and part of that comes with a price, for example, the seats are not quite as comfortable as others. I am ok with a pay for beverage and snack service as I prefer my own anyway so this was not a concern. I thought overall, having a great flight crew and on time service was definitely worth losing some of the frills from other carriers.

Sadly there was a crew member very rude with my kid and with me.

They canceled the flight and didn't assist in getting a new flight on any airline. I had to spend 10 hrs in the airport after getting a ticket On Delta for twice as much. I've flown Spirit many times and this was my worst experience I've had.

Late taking off. ATC sent us circling around Chicago for almost an hour, after landing taxied for 40 minutes.

We had too many delays for the crew not the plane

Everything you need to know for your flight to South America

Information on your arrival and departure airports