$140 Find Cheap Flights from San Antonio to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Antonio to South America departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from San Antonio to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$568
Bogotá
Bogotá1 stop$335
Cartagena
Cartagena2 stops$420
Santiago
Santiago2 stops$762
Quito
Quito3 stops$518
Cali
Cali1 stop$373
Guayaquil
Guayaquil2 stops$602
Cusco
Cusco2 stops$947
Pereira
Pereira2 stops$481
Montevideo
Montevideo2 stops$1,174
Barranquilla
Barranquilla1 stop$367
Santa Marta
Santa Marta2 stops$1,056
Lima
Lima2 stops$568
Bogotá
Bogotá1 stop$335
Cartagena
Cartagena2 stops$420
Santiago
Santiago2 stops$762
Quito
Quito3 stops$518
Cali
Cali1 stop$373
Guayaquil
Guayaquil2 stops$602
Cusco
Cusco2 stops$947
Pereira
Pereira2 stops$481
Montevideo
Montevideo2 stops$1,174
Barranquilla
Barranquilla1 stop$367
Santa Marta
Santa Marta2 stops$1,056

Book Cheap San Antonio to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Antonio to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Antonio to South America

Mon, Sep 22 - Thu, Sep 25
Spirit Airlines Logo
7:17 pm - 1:14 pmSAT-MDE
17h 57m1 stop
Spirit Airlines Logo
1:24 am - 6:12 pmMDE-SAT
16h 48m1 stop
$314Spirit Airlines
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Thu, Sep 25 - Wed, Oct 1
Spirit Airlines Logo
2:54 pm - 12:28 amSAT-MDE
9h 34m2 stops
Spirit Airlines Logo
1:24 am - 6:12 pmMDE-SAT
16h 48m1 stop
$319Spirit Airlines
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Sat, Sep 13 - Tue, Sep 30
United Airlines Logo
5:30 am - 7:20 pmSAT-BOG
13h 50m1 stop
United Airlines Logo
8:30 am - 10:49 amBOG-SAT
26h 19m1 stop
$406United Airlines
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Sat, Sep 13 - Tue, Sep 30
United Airlines Logo
5:30 am - 7:20 pmSAT-BOG
13h 50m1 stop
United Airlines Logo
8:30 am - 8:38 amBOG-SAT
24h 08m1 stop
$407United Airlines
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Tue, Sep 23 - Wed, Oct 1
Delta Logo
6:35 am - 3:15 amSAT-BOG
20h 40m2 stops
Delta Logo
2:55 pm - 9:32 amBOG-SAT
18h 37m1 stop
$415Delta
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Thu, Sep 25 - Wed, Oct 1
American Airlines Logo
7:59 am - 9:17 pmSAT-BOG
13h 18m2 stops
American Airlines Logo
12:25 am - 11:54 amBOG-SAT
11h 29m1 stop
$419American Airlines
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Wed, Oct 15 - Fri, Oct 24
Delta Logo
6:21 pm - 1:40 pmSAT-BOG
19h 19m1 stop
Delta Logo
2:55 pm - 12:20 amBOG-SAT
9h 25m1 stop
$420Delta
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Sat, Sep 13 - Mon, Sep 29
American Airlines Logo
8:00 am - 10:40 pmSAT-BOG
14h 40m1 stop
American Airlines Logo
12:25 am - 6:42 pmBOG-SAT
18h 17m1 stop
$448American Airlines
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Tue, Dec 9 - Thu, Dec 11
LATAM Airlines Logo
12:15 pm - 10:55 amSAT-BOG
21h 40m2 stops
LATAM Airlines Logo
1:35 am - 12:25 amBOG-SAT
23h 50m2 stops
$468LATAM Airlines
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Sat, Oct 11 - Sun, Oct 26
LATAM Airlines Logo
5:15 pm - 10:55 amSAT-BOG
41h 40m2 stops
LATAM Airlines Logo
10:55 am - 8:28 pmBOG-SAT
33h 33m2 stops
$483LATAM Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for San Antonio to South America flights

Get data-powered insights and trends into flights from San Antonio to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from San Antonio to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Antonio to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Antonio to South America is August, when tickets cost $677 (return) on average. On the other hand, the most expensive months are December and May, when the average cost of round-trip tickets is $1,095 and $775 respectively.

What’s the cheapest day of the week to fly from San Antonio to South America?

The average price of all round-trip flights from San Antonio to South America clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to South America on a Monday and more expensive on a Friday. On your return trip to San Antonio, you should consider flying back on a Thursday, and avoid Fridays for better deals.

How far in advance should I book a flight from San Antonio to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Antonio to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Antonio to South America, you should book around 3 weeks before departure, which saves you about 11% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 8 weeks before departure.

Good to know

Low seasonApril
Cheapest flight$140
Best time to beat the crowds but there is an average 41% increase in price.
Most popular time to fly with an average 29% increase in price.
Flight from San Antonio to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from San Antonio to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Antonio to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Antonio to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Antonio to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Antonio to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Antonio to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Antonio to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Antonio to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $717 on average. Morning departures are around 1% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $874.

Reviews of the top 5 airlines serving from San Antonio to South America

 
Need help choosing which airline to fly with from San Antonio to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7977 reviews
7.9Comfort
7.9Entertainment
8.2Boarding
8.5Crew
7.3Food
Airline reviews

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

4.0 Okaypuravi, Aug 2025LGA - STL
Read more Delta reviews

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Nothing special. The crew never went out of their way for anything.

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Delayed due to thunderstorms and no in-flight service due to rough weather — both of which are out of Delta’s control. Flight was good overall.

The flight attendants in SLC were rude. I arrived 40 minutes early to gate. Ticket said I needed check in for seat assignments and tried check in and attendants said they weren’t doing it. And proceeded to never call me to give me a ticket so when time to board I received the very last seat. Please relay to employees to do their job better..,

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

The seats got pretty uncomfortable pretty fast. The armrests are bigger than on other planes, so I had less room in the actual seat. My butt hurt by the end of the flight. :/ comfort was the primary issue. The crew were fantastic!

I believe that a four-hour trip should have a meal. Delta had none.

Great flight with Delta! Boarding was quick and easy, the amenities were solid, and the plane was in great shape. The flight attendants had a fun, lively energy while staying professional. All in all, a smooth trip — even managed to catch up on some rest. Thanks, Delta!

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

My entertainment did not work. I was very tired from the botched connection, and the poor sleep

Lost ,y connection due to a mechanical delay, huge line to get new connection and vouchers

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

It was a very good flight, no entertainment is the reason for not checking that box.

Flight was on time, good service, but there was no free WiFi, even for first class passengers

It was good in general. The Crew during the flight were very nice at all times.

My flight was delayed, then I got transferred to a new flight that was also delayed- which wasn’t Aeromexico’s fault, it was because of weather conditions. Most of the crew was very nice and patient, except for one or two flight attendants who were rude. The entertainment wasn’t on, so all the screens were off.

My wife's entertainment system did not work. Payed for flight upgrade but did not receive advertised "free WiFi".

Annoying that we had to go to departures and get boarding passes. Should allow us to be booked all the way through, this is the only airline i have this problem with in MEX. Late boarding and take off

the guy in front of me put his seat back immediately...and then left it back including thru landing and taxiing to the runway. attendants did not check/ask him to put it up for landing.

Lousy No wheelchair. As normal at Atlanta Cheap airline Cheap aero plane. - Neither entertainment nor food on a 5 hour saga

Ok. But we arrived to a remote terminal which meant that a bus had to take us to the terminal building

Terrible. The flight arrives 2 hr later, no AC. One of the worst flights ever

The plane was so outdated, that it made it uncomfortable. The temperature was hot during the whole flight

Plane was crowded and even when we hit altitude, the plane was hot, not enough air flow.

Flight was delayed and missed my connection Lufthansa didn’t respond.

the delay for 3 hours was understandable due to weather conditions but the flight should’ve provided some on flight compensations or at least provide more food.

United could have one single once of customer service. No human United employee would help me with the invalid mileage plus number, they said I had to speak with the computer.

A little bit more leg room in premium economy. I am 6’4”.

Overall it was good. I missed my connection but I was put on another flight.

Although the flight was delayed the crew and the flight itself were very good. Couldn't fault anything and after the disappointment of being abandoned in the US by BA it was a welcome relief to travel with United

Gate agent did not hold flight for connection, provided no assistance to get new flight

Boarding experience was smooth. Flight attendants were friendly and helpful. Entertainment system on the Houston-Edmonton flight did not function for passengers on the left side of the aisle. On the bird's eye flight from Quito to Houston, they should not serve a meal. No one needs to eat after midnight and it is disturbing for those passengers trying to sleep.

Smooth flight. Boarding was chaotic. Could not hear the gate agent over the intercom. People were lined up in the wrong lines. Groups one and two were told to board through line one and group 3 through line 2. All very confusing. Once in the air, the flight was smooth. There was no entertainment option on this aircraft, even though it was a larger aircraft.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

My Internet did not work for Outlook email or basically anything. I paid for one hour of in-flight usage and it was terrible. I spent a lot of time on different sites and browsers with no luck and a lot of frustration. Other than that, the flight was on time, crew was nice, service was fine. Seat was OK even though I paid for the extra 6 inches. I cannot imagine how tight the seats in the back must be.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

No issues. They did change our gate FOUR times in about 30 minutes which was mildly annoying but the flight was fine.

Great flight. No issues at all. I still think boarding could be more efficient but otherwise, a good experience.

Crew should be nicer and emphatic with customers. Same cookies as the past 20 years. Seat are ok and the plane was clean though it was delayed.

Very poor delay in dfw was really bad n long

Because of rescheduling, they had to put me on a flight that didn't go through Dallas

The flight got delayed 2.5 hrs due to a maintenance issue that cause a domino effect. American should have spare planes for when something like this happens.

Flight was delayed again and again ultimately almost three hours getting us to our location at close to midnight by the time we got in and out of airport to destination. I had taken time off work to enjoy an evening at destination and that was now wasted

Everything you need to know for your flight to South America

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