$266 Find Cheap Flights from San Diego to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Diego to Panama departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from San Diego to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City3 stops$596
David
David2 stops$1,105
Panama City
Panama City3 stops$596
David
David2 stops$1,105

Book Cheap San Diego to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Diego to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Diego to Panama

Fri, Aug 21 - Sat, Aug 29
Multiple Airlines Logo
9:29 pm - 1:55 am
SAN
-
PTY
26h 26m
3 stops
Multiple Airlines Logo
5:30 am - 4:11 pm
PTY
-
SAN
12h 41m
2 stops
$596Multiple Airlines
Sun, Oct 25 - Sat, Oct 31
Multiple Airlines Logo
6:48 pm - 10:30 am
SAN
-
PTY
13h 42m
2 stops
Multiple Airlines Logo
7:50 pm - 7:59 pm
PTY
-
SAN
26h 09m
2 stops
$618Multiple Airlines
Thu, Aug 27 - Wed, Sep 2
Multiple Airlines Logo
7:00 am - 1:55 am
SAN
-
PTY
16h 55m
2 stops
Multiple Airlines Logo
5:30 am - 7:02 pm
PTY
-
SAN
15h 32m
2 stops
$620Multiple Airlines
Wed, Aug 26 - Sun, Aug 30
Multiple Airlines Logo
1:00 pm - 10:30 am
SAN
-
PTY
19h 30m
2 stops
Multiple Airlines Logo
5:30 am - 1:28 pm
PTY
-
SAN
33h 58m
2 stops
$627Multiple Airlines
Fri, Sep 25 - Fri, Oct 2
Copa Airlines Logo
9:03 pm - 5:20 am
SAN
-
PTY
6h 17mnonstop
Copa Airlines Logo
1:48 pm - 6:30 pm
PTY
-
SAN
6h 42mnonstop
$676Copa Airlines
Thu, Jun 18 - Thu, Jun 25
Copa Airlines Logo
8:32 pm - 4:26 pm
SAN
-
DAV
17h 54m
2 stops
Copa Airlines Logo
7:54 pm - 6:40 pm
DAV
-
SAN
24h 46m
1 stop
$1,105Copa Airlines
Tue, Oct 13 - Sat, Oct 17
United Airlines Logo
8:00 am - 9:10 am
SAN
-
DAV
23h 10m
2 stops
United Airlines Logo
9:50 am - 9:25 pm
DAV
-
SAN
37h 35m
2 stops
$1,135United Airlines
Tue, Oct 13 - Sat, Oct 17
United Airlines Logo
8:00 am - 9:10 am
SAN
-
DAV
23h 10m
2 stops
United Airlines Logo
9:50 am - 1:17 pm
DAV
-
SAN
29h 27m
2 stops
$1,150United Airlines
Tue, Oct 13 - Sat, Oct 17
United Airlines Logo
7:41 pm - 9:10 am
SAN
-
DAV
35h 29m
3 stops
United Airlines Logo
9:50 am - 5:46 pm
DAV
-
SAN
33h 56m
2 stops
$1,253United Airlines
Thu, Jun 18 - Thu, Jun 25
Copa Airlines Logo
6:20 am - 9:03 am
SAN
-
DAV
24h 43m
2 stops
Copa Airlines Logo
9:50 am - 11:54 pm
DAV
-
SAN
16h 04m
2 stops
$1,291Copa Airlines
Booking Insights

KAYAK's insights & trends for San Diego to Panama flights

Get data-powered insights and trends into flights from San Diego to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest San Diego to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from San Diego found in the last 72 hours was to Panama City, at $398 round-trip. The most popular route is from San Diego (SAN) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $398.

What is the cheapest time of day to fly to Panama?

The average price for all round-trip flights from San Diego to Panama depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $517 on average. The most expensive time of day to fly to Panama is generally at night, which is peak travel time and where the average cost of a ticket is $517.

Can I save money by flying with a layover from San Diego to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $651 on average.

What is the cheapest month to fly from San Diego to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Diego to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Diego to Panama is September, when tickets cost $145 (return) on average. On the other hand, the most expensive months are April and January, when the average cost of round-trip tickets is $510 and $367 respectively.

What’s the cheapest day of the week to fly from San Diego to Panama?

The average price of all round-trip flights from San Diego to Panama clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from San Diego to Panama, look for departures on Wednesdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from Panama, Monday is the cheapest day to fly and Wednesday is the most expensive.

How far in advance should I book a flight from San Diego to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Diego to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Diego to Panama, you should book around 3 weeks before departure, which saves you about 37% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$266
Best time to beat the crowds but there is an average 45% increase in price.
Most popular time to fly with an average 4% increase in price.
Flight from San Diego to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from San Diego to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Diego to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Diego to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Diego to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Diego to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Diego to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Diego to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Diego to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from San Diego to Panama

 
Need help choosing which airline to fly with from San Diego to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8457 reviews
7.9Comfort
8.1Boarding
7.2Food
8.5Crew
7.8Entertainment
Airline reviews

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

10.0 ExcellentTeresa, Apr 2026
SMF - LAX
Read more Delta reviews

While they turned off most cabin lights to allow people to sleep, I was bothered by how bright the side lights still were. It was still quite bright for me in a window seat, when I wish I could have slept!

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

N Everything was perfect from boarding to assistance to baggage in Tampa

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

Fast, lovely scenery, great info on the Delta flight screen about landmarks we were flying over. Great landing!

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I took seat 15A in anticipation of window seat, there is no window.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

No screens or meal options. Freezing cold. Dirty seats. Left late.

I liked that my son and I were reseated next to each other (we had different bookings). I liked that it was a directg flight and mostly on time. I liked that you provided pillows and blankets. Flight attendants were generally courteous. The messaging through wifi did not work well. The food was not good. Seats are very narrow and I felt slightly claustraphobic in the window seat.

Some crew were unfriendly or in some cases just straight up rude.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

United Airline crews were very friendly and very attentive. 12 hours flight was gone like in a shorter one.

Food was surprisingly delicious. Space in the seat is horrible when the seating front is reclined. Movie offerings were terrible. Crew was friendly and helpful.

Flight itself excellent, but delayed so missed connection & got to destination 2 hrs later

Due to cancellation of connecting flight (Lufthansa) I didn’t fly with United

It was a red-eye, but the flight felt surprisingly quick. The seats were very comfortable, and that made resting much easier. I also want to thank the gentleman seated next to me, who graciously moved so my mom could sit beside me. We slept almost the entire way. The cabin crew was respectful in not disturbing us, while also being courteous and professional throughout. Thank you, United.

Everything you need to know for your flight from San Diego to Panama

Information on your arrival and departure airports