$371 Find Cheap Flights from San Diego to Panama - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Diego to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Panama City
Panama Citynonstop$660
David
David2 stops$1,434
Panama City
Panama Citynonstop$660
David
David2 stops$1,434
Booking Insights

Price, demand and travel trends for San Diego to Panama flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Are flights from San Diego to Panama cheaper or more expensive than last year?

Fares from San Diego to Panama are running about 21% higher than they were around this time last year, averaging $726 round-trip.

What are the cheapest fares from San Diego to Panama right now?

The cheapest fares from San Diego to Panama on KAYAK in the last week were to Panama City Tocumen Intl (PTY) from $660 round-trip, and to David Enrique Malek (DAV) from $1,434 round-trip.

What’s the cheapest month to fly from San Diego to Panama?

May is the cheapest time of year to fly, with average fares of $654. Prices are highest in December, when average flight costs increase to around $1,105.

When is the best time to book flights from San Diego to Panama?

Book your flights 18 weeks before your trip. KAYAK data collected over the past 12 months shows that booking in this window can save you around 44% compared to booking last-minute (within 2 weeks of departure).

Which airport in Panama is the cheapest to fly to from San Diego?

Based on KAYAK data from the past 12 months, the cheapest airports to fly into Panama are:

• Panama City Tocumen Intl (PTY) (avg. price $726)
• David Enrique Malek (DAV) (avg. price $886)

What’s the cheapest day to fly from San Diego to Panama?

Wednesday tends to be the cheapest day to fly from San Diego to Panama, while Saturday is the most expensive. Fares run about 37% higher that day, based on the past 12 months of KAYAK data.

What's the cheapest time of day to fly from San Diego to Panama?

Data from the past 12 months shows it's cheapest to fly to Panama during the night with average prices of $721. The afternoon is the most expensive time to fly, with average prices of $1,225.

Key details for San Diego to Panama flights

Low season

September

Cheapest flight

$371
Beat the crowds with an average 46% drop in travelers.
The most popular month to fly with an average 56% increase in travelers.
One-way flight from San Diego to Panama City

Your San Diego to Panama flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from San Diego to Panama?

    Fares from San Diego to Panama are around their usual level right now. A round-trip under $630 is considered a good deal, so it's worth keeping an eye out, or setting a Price Alert to catch price changes.

  • How much should I budget for a flight from San Diego to Panama?

    Over the past 12 months, round-trip fares from San Diego to Panama have ranged from $630 to $970.

  • What airlines fly nonstop from San Diego to Panama?

    Based on the flight schedule for the next 3 months, just one airline regularly flies nonstop from San Diego to Panama: Copa Airlines.

  • Where in Panama can I fly nonstop from San Diego?

    Based on the flight schedule for the next 3 months, you can only fly nonstop from San Diego to Panama City.

  • Is it cheaper to fly with a layover from San Diego to Panama?

    Yes, nonstop flights from San Diego to Panama average $695 over the past 12 months. Flights with a layover can cost less, cheapest when connecting through Panama City Tocumen Intl (PTY), with average fares of $654.

  • How long is a flight from San Diego to Panama?

    Flights from San Diego to Panama take 6h 06m on average.

  • Which cabin classes are available on flights from San Diego to Panama?

    On flights from San Diego to Panama you can book Economy Class, Business Class or First Class.

  • What are some popular landmarks in Panama?

    KAYAK travelers' favorite landmarks in Panama include:

    • ATLAPA Conventions Center
    • Panama Old Cathedral
    • Veneto Casino
    • Ancon Hill

  • What are the earliest and latest flights from San Diego to Panama?

    The earliest nonstop flight from San Diego to Panama departs at 10:30 pm and the latest departs at 10:30 pm. Nonstop flights take about 6h 06m.

Your guide to booking San Diego to Panama flights

Get tips on when to book, when to fly and what to know before your trip.
  • If you can plan ahead, the sweet spot for booking your flight is 18 weeks before your trip. KAYAK data shows fares in this window are around 44% lower than last-minute bookings (made within 2 weeks of departure). Not ready to commit? Set a Price Alert and we'll let you know when prices change.
  • If your travel dates are flexible, book your trip for May when flights are typically cheapest and avoid December when prices are at their highest.
  • Flying on Wednesday is usually the cheapest. Flights on Saturday cost about 37% more on average, so being flexible with your travel dates could help you save.
  • If you're looking to save, Panama City Tocumen Intl (PTY) is the cheapest airport to fly into from San Diego. If you have onward travel, don't forget to factor in the cost of your journey by train, bus or domestic flight.
  • Start your trip in Panama City, which is the most popular destination in Panama. From there, it's easy to continue on to other popular destinations such as Bocas del Toro, Río Hato and Boquete.
  • If you want the shortest trip, choose the San Diego to Panama nonstop route. If you'd rather save money, the route via Panama City Tocumen Intl (PTY) is usually the cheapest.

Reviews of the top 3 airlines serving from San Diego to Panama

 
Need help choosing which airline to fly with from San Diego to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1552 reviews
8.1Crew
6.9Entertainment
7.8Boarding
7.4Comfort
7.0Food
Airline reviews

We where skipped for this flight will not head to Panama until tonight..

2.0 MediocreRussell, Jul 2026
Read more Copa Airlines reviews

We where skipped for this flight will not head to Panama until tonight..

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

It was good, plane is a bit older so seats are somewhat flat

Very good flight and crew Food was a surprise on a short flight

Biggest issue was that they only had two restrooms in the back of the aircraft. Too many people for only two restrooms. The trash was overflowing and there was paper on the floor too. Long lines in the isle to use it. Food was also a bit meh. They don’t offer snacks with drinks, so you might want to buy a snack to hold you off on a longer trip, since the meals are very small.

Everything was smooth and crew was very polite and friendly.

I like that they served a mail, I’m not sure about the in-flight entertainment. I didn’t really check. staff helped me with my luggage. Smooth boarding smooth takeoff smooth flight

The seats had plenty of leg room and the staff were very nice.

Copa performed as expected for the amount of money I was willing to spend for the flight; it wasn’t exceptional but it was not bad in any way either. The crew was good; friendly and straightforward. The food was airplane food, so no expectations there and the entertainment was lacking but that was my fault for owning an IPhone with a charging port that’s not compatible with the rest of the world. I’d fly Copa again.

Left my bags in origin city on a business class ticket , spent about 2-3 days in the same clothes plus the flight .

Entertainment was great. Seats were good. They did not have my pre-ordered hot food product available but did comp me something cold in place of the item.

Food was good. Clean aircraft. But why do the airlines make the seats so narrow?! Your executives should have ride in a seat so restrictive for 11 hours and see how miserable it is! When.we got to MUC they changed my boarding gate 3 times for my next flight!!!!

Flight was on time, clean, etc. Despite connecting to your wi fi I was unable to use your app to watch entertainment.

The back to back mechanical delays from Denver to San Diego and then on my return flight from Denver to Great Falls it added extra time both ways

Service was professional and quick. Premium economy seat was comfortable given the class

The staff was extremely helpful and friendly at all times! They went above and beyond to get us into an earlier flight in San Diego to make our connection in SFO possible, because our original flight did actually not make it! I did so much appreciate the UA team and how they made this possible. We also didn’t have seats together on the long flight to Singapore, but they found us seats together last moment with no additional cost! Nobody sat next to us, so that we were able to sleep! Thanks to UA for improving their service and Underpricer for booking this trip! Please be careful: 1,5 hrs for transfer in San Francisco might not be enough time in the future

Over 2.5 hour maintenance delay on first morning flight with no acknowledgement, compensation or even gesture of good will. Aircraft had overnighted at airport so issue should have been addressed prior to boarding. Over 3.5 hours before first slow and deliberate beverage service.

Complimentary light meal would be appreciated. But great flight crew service on all legs

The food was terrible this time. Otherwise pleasant, quiet, on-time.

I was in first class. The outlets at my seat did not work. The plane was shabby and run down. I had prepurchsed a day subscription for internet that was not redeemable. I had to repurchase the internet for my flight and then it didn’t work anyway. Quite disappointed in what was supposed to be the launch of a great vacation.

first leg from san diego to chicago, only had cookies for snack. 1 flavor of sparkling water chicago to washington dc had option of cookies, pretzels, or gold fish. had 2 flavors of sparkling water. 2nd flight better however the best part was there was no delays!!! Got to chicago and washington dc early. That was wonderful!!!!

I was truly shocked at how poor this flight went. The crew was not friendly during the checking process. The asked for people to gate check and were rude about it. They didn't handle my luggage with care. When I got to my seat I noticed a large section of the ceiling vent area was, no joke, TAPED TOGETHER WITH CLEAR PACKING TAPE! To add insult to injury, the back rest button was disabled on my seat and all the seats I could see. The wifi, never connected for me, despite troubleshooting it for a while. I did everything from restarting my wifi/phone to forgetting the network and restarting the app. But that didn't stop the mandatory 2 ads from playing every single time. Even the bags took over 45 mins to arrive at the carousel. Everything about this flight was a flop and I am beginning to notice that some of these events are becoming a trend. Perhaps it's time I switch loyalty programs.

Had to pay for WiFi, delayed start, and sat on the runway forever.

More space for economy, and the bathroom size is only for people with size XS

Well, true to American Airlines, both of my flights were delayed. But it’s a good thing that American is so consistently incompetent because if the first flight was delayed in the second flight was on time then I might’ve had a problem..

Was not able to do a online check-in because the American Airlines system doesn't store our visa or other passport information, allowing us to have a trouble-free check-in. We were forced to have to check-in at the counter which Changes are upgrade status given that we were not able to check in much earlier.

The entertainment package was vast and the selections were very current. Keep updating it was great.

The seat was so hard my tailbone was aching The crew was kind of a b**** because I made a joke that I didn't care if they close the door I total c*** when she was trying to f****** act like she was mad at me because I said that The flight was bumpy. Sure you didnt have control over that.

Cramped seats. FAA should make airlines have more legroom, for even short people complain

Flight was full, and would have preferred an aisle seat, but due to getting a late ticket ,the seat I had was adequate. The flight crew were very help full and hard working. Food and drink were excellent for the 11hr flight. Overall I was pleased with flight, and would recommend British Airways again.

More options for your flight from San Diego to Panama

Complete your trip to Panama with a hotel stay or car rental