$376 Find Cheap Flights from San Francisco to Panama - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Cheap Flights from San Francisco to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Panama City
Panama City1 stop$673
David
David1 stop$1,057
Panama City
Panama City1 stop$673
David
David1 stop$1,057
Booking Insights

KAYAK's insights & trends for San Francisco to Panama flights

Get data-powered insights and trends into flights from San Francisco to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest San Francisco to Panama flight route?

The cheapest ticket to Panama from San Francisco found in the last 5 days was to Panama City, at $580 round-trip. The most popular route is from San Francisco (SFO) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 5 days was $580.

What is the cheapest time of day to fly to Panama?

The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $763 on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $803.

Can I save money by flying with a layover from San Francisco to Panama?

No, with an average price for the route of $931, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from San Francisco to Panama?

The cheapest month for flights from San Francisco to Panama is January, when tickets cost $654 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $941 and $826 respectively.

What’s the cheapest day of the week to fly from San Francisco to Panama?

For San Francisco to Panama, Wednesday is the cheapest day to fly on average and Saturday is the most expensive. Flying from Panama back to San Francisco, the best deals are generally found on Friday, with Sunday being the most expensive.

How far in advance should I book a flight from San Francisco to Panama?

To get a below average price on the flight from San Francisco to Panama, you should book around 5 weeks before departure, which saves you about 13% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 16 weeks before departure.

Good to know

Low season

September

Cheapest flight

$376
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly with an average 27% increase in price.
Flight from San Francisco to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from San Francisco to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Francisco to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Francisco to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Francisco to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from San Francisco to Panama

 
Need help choosing which airline to fly with from San Francisco to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1553 reviews
7.4Comfort
6.9Food
7.8Boarding
8.1Crew
6.8Entertainment
Airline reviews

We where skipped for this flight will not head to Panama until tonight..

2.0 MediocreRussell, Jul 2026
Read more Copa Airlines reviews

We where skipped for this flight will not head to Panama until tonight..

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

It was good, plane is a bit older so seats are somewhat flat

Very good flight and crew Food was a surprise on a short flight

Biggest issue was that they only had two restrooms in the back of the aircraft. Too many people for only two restrooms. The trash was overflowing and there was paper on the floor too. Long lines in the isle to use it. Food was also a bit meh. They don’t offer snacks with drinks, so you might want to buy a snack to hold you off on a longer trip, since the meals are very small.

Everything was smooth and crew was very polite and friendly.

I like that they served a mail, I’m not sure about the in-flight entertainment. I didn’t really check. staff helped me with my luggage. Smooth boarding smooth takeoff smooth flight

The seats had plenty of leg room and the staff were very nice.

Copa performed as expected for the amount of money I was willing to spend for the flight; it wasn’t exceptional but it was not bad in any way either. The crew was good; friendly and straightforward. The food was airplane food, so no expectations there and the entertainment was lacking but that was my fault for owning an IPhone with a charging port that’s not compatible with the rest of the world. I’d fly Copa again.

Left my bags in origin city on a business class ticket , spent about 2-3 days in the same clothes plus the flight .

Sitting in coach even in the larger leg space is extremely uncomfortable and the staff pay no attention.

The pilot was late so we didn’t take off til almost 2 hours late.

It was a short, comfortable flight. It did leave an hour late due to the pilot having to be replaced (family emergency) but that didn’t inconvenience myself & my friend. The situation was explained, eventually.

Excellent communication from the staff. We actually arrived early. Very friendly and professional staff.

No extra snacks were available. Meals quality is terrible. Crew was not friendly.

Lost one piece of luggage even though I checked in 2.5 hours before the flight

It was perfect! United Airlines staff was extremely caring, super friendly and professional

United has maintenance issues and can then never recover. No operations ability and simple issues always turn into multiple hours long cascading delays. Worst airline on earth.

I paid for a confirmed upgraded aisle seat and was moved to a center seat in the back of the plane at the last minute.

Same as last comment. Food sucks. Quality. Not surprising most people have no clue about nourishment Clearly

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

Boarding, crew were excellent, food was ok and entertainment need to improve

There isn't much space in-between seats and even water needs to be paid for during the flight.

We were not aware carry-on bags cost extra until we arrived at the airport so, we were charged $240.00 for two small carry- on bags! There was a substantial fee for drinks and snacks. No wifi, or other entertainment was available. Waiting areas were crowded and uncomfortable.

Ok, but these people don’t give you nothing no snack no water

No water for a 5 hour flight entertainment not working seats with little room for knees when person in front of me reclined kept bumping my knees.

Awful. I checked in online and there was no option to pay for baggage, at the airport when I checked in my baggage was received and Iwas not charged. When I got to LA during the boarding process I was told I didn't pay for baggage, the crew resolved I was let in the plane. When I got to my final destination my baggage was not there. It took me two days to receive my baggage. Bad service ever!

Wasn’t able to take the trip and no one could help me with a refund or rescheduling

Everything you need to know for your flight from San Francisco to Panama

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