$287 Find Cheap Flights from San Francisco to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Panama departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from San Francisco to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City1 stop$693
David
David2 stops$1,186
Panama City
Panama City1 stop$693
David
David2 stops$1,186

Book Cheap San Francisco to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Panama

Thu, Jul 9 - Thu, Jul 16
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
Avianca Logo
10:10 am - 10:35 pm
PTY
-
SFO
14h 25m
2 stops
$693Avianca
Sat, Jul 11 - Mon, Aug 10
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
Avianca Logo
3:50 pm - 6:25 am
PTY
-
SFO
16h 35m
2 stops
$699Avianca
Sat, Jun 6 - Sat, Jun 20
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
$709Avianca
Tue, Jun 23 - Sun, Jul 5
Avianca Logo
2:30 am - 1:55 am
SFO
-
PTY
21h 25m
1 stop
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
$716Avianca
Sun, Jun 21 - Sun, Jun 28
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
Avianca Logo
5:30 am - 10:35 pm
PTY
-
SFO
19h 05m
1 stop
$719Avianca
Fri, Jun 26 - Sat, Jul 11
Avianca Logo
11:55 pm - 5:00 pm
SFO
-
PTY
15h 05m
2 stops
Avianca Logo
10:10 am - 10:35 pm
PTY
-
SFO
14h 25m
2 stops
$721Avianca
Tue, Jun 16 - Thu, Jul 9
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
$722Avianca
Thu, Jul 9 - Sun, Jul 19
Avianca Logo
11:55 pm - 5:00 pm
SFO
-
PTY
15h 05m
2 stops
Avianca Logo
3:50 pm - 6:25 am
PTY
-
SFO
16h 35m
2 stops
$726Avianca
Mon, Aug 31 - Fri, Sep 4
United Airlines Logo
11:59 pm - 9:10 am
SFO
-
DAV
31h 11m
2 stops
United Airlines Logo
9:50 am - 12:27 am
DAV
-
SFO
16h 37m
2 stops
$1,186United Airlines
Mon, Aug 31 - Fri, Sep 4
United Airlines Logo
11:59 pm - 9:10 am
SFO
-
DAV
31h 11m
2 stops
United Airlines Logo
9:50 am - 11:40 pm
DAV
-
SFO
15h 50m
1 stop
$1,268United Airlines
Booking Insights

KAYAK's insights & trends for San Francisco to Panama flights

Get data-powered insights and trends into flights from San Francisco to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest San Francisco to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from San Francisco found in the last 3 days was to Panama City, at $489 round-trip. The most popular route is from San Francisco (SFO) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 3 days was $489.

What is the cheapest time of day to fly to Panama?

The average price for all round-trip flights from San Francisco to Panama depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Panama is generally in the morning, when round-trip flights cost $695 on average. The most expensive time of day to fly to Panama is generally at night, which is peak travel time and where the average cost of a ticket is $705.

Can I save money by flying with a layover from San Francisco to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $817, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from San Francisco to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Panama is October, when tickets cost $207 (return) on average. On the other hand, the most expensive months are July and August, when the average cost of round-trip tickets is $443 and $378 respectively.

What’s the cheapest day of the week to fly from San Francisco to Panama?

The average price of all round-trip flights from San Francisco to Panama clicked on KAYAK for each day over the last 12 months.

For San Francisco to Panama, Monday is the cheapest day to fly on average and Saturday is the most expensive. Flying from Panama back to San Francisco, the best deals are generally found on Friday, with Sunday being the most expensive.

How far in advance should I book a flight from San Francisco to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Panama, you should book around 8 weeks before departure, which saves you about 22% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 8 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$287
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 25% increase in price.
Flight from San Francisco to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from San Francisco to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Francisco to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Francisco to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Francisco to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from San Francisco to Panama

 
Need help choosing which airline to fly with from San Francisco to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1576 reviews
7.8Boarding
8.1Crew
7.4Comfort
6.8Entertainment
6.9Food
Airline reviews

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

2.0 MediocreFred, May 2026
UIO - PTY
Read more Copa Airlines reviews

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Easy of boarding, helpfully staff at check in, surprisingly comfortable seating

Lost of requested seat assignments. Lost my husband's meal choice

My service dog and I were asked to deplane just before they closed the door - clearly very last minute they couldn’t find the documentation that I have filled out many many times before that is for flying service animals. I purposely purchase 3seats (a whole row) since he is large and not all passengers want to sit next to a dog on a cross country flight. The plane departed with my husband on it!!! They made me fill out a hard copy of the same form and had to reschedule me on a later flight where they could find 3 seats together!! I’ve done this so many times before - clearly the error was on their part in a technology glitch - but really people - do better!! Very traumatic - and my husband had to wait for us when he landed ….so bad. Poor pup was confused and tired.

My flight time was changed without any notification to me which ruined my time sensitive plans so I ended up completely changing my travel plans and no reimbursement.

No screens or meal options. Freezing cold. Dirty seats. Left late.

I liked that my son and I were reseated next to each other (we had different bookings). I liked that it was a directg flight and mostly on time. I liked that you provided pillows and blankets. Flight attendants were generally courteous. The messaging through wifi did not work well. The food was not good. Seats are very narrow and I felt slightly claustraphobic in the window seat.

Some crew were unfriendly or in some cases just straight up rude.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

United Airline crews were very friendly and very attentive. 12 hours flight was gone like in a shorter one.

Flight itself excellent, but delayed so missed connection & got to destination 2 hrs later

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Everything you need to know for your flight from San Francisco to Panama

Information on your arrival and departure airports