$203 Find Cheap Flights from San Francisco to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Panama departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from San Francisco to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City1 stop$491
David
David2 stops$1,013
Panama City
Panama City1 stop$491
David
David2 stops$1,013

Book Cheap San Francisco to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Panama

Sat, Mar 14 - Wed, Mar 18
Avianca Logo
2:35 am - 6:55 pm
SFO
-
PTY
14h 20m
1 stop
Avianca Logo
5:50 pm - 1:00 pm
PTY
-
SFO
21h 10m
2 stops
$491Avianca
Tue, Mar 10 - Sun, Mar 15
Avianca Logo
2:35 am - 6:55 pm
SFO
-
PTY
14h 20m
1 stop
Avianca Logo
7:50 pm - 1:00 pm
PTY
-
SFO
19h 10m
1 stop
$493Avianca
Mon, Jul 13 - Tue, Jul 21
Avianca Logo
7:45 am - 1:55 am
SFO
-
PTY
16h 10m
2 stops
Avianca Logo
10:10 am - 11:55 pm
PTY
-
SFO
15h 45m
2 stops
$495Avianca
Mon, Apr 27 - Sat, May 9
Copa Airlines Logo
5:00 am - 9:08 am
SFO
-
DAV
26h 08m
2 stops
Copa Airlines Logo
9:38 am - 11:59 pm
DAV
-
SFO
16h 21m
2 stops
$1,013Copa Airlines
Sat, May 16 - Wed, May 20
United Airlines Logo
4:45 pm - 8:58 am
SFO
-
DAV
38h 13m
2 stops
United Airlines Logo
9:38 am - 7:22 am
DAV
-
SFO
23h 44m
2 stops
$1,056United Airlines
Sat, Apr 4 - Sun, Apr 12
United Airlines Logo
12:45 am - 9:08 am
SFO
-
DAV
30h 23m
2 stops
United Airlines Logo
10:05 am - 7:16 am
DAV
-
SFO
23h 11m
2 stops
$1,071United Airlines
Sun, Apr 26 - Sat, May 9
Copa Airlines Logo
1:23 am - 7:38 pm
SFO
-
DAV
16h 15m
1 stop
Copa Airlines Logo
8:31 am - 11:40 pm
DAV
-
SFO
17h 09m
1 stop
$1,110Copa Airlines
Sun, Apr 5 - Sun, Apr 12
Copa Airlines Logo
8:37 pm - 9:08 am
SFO
-
DAV
10h 31m
1 stop
Copa Airlines Logo
8:32 am - 11:40 pm
DAV
-
SFO
17h 08m
1 stop
$1,150Copa Airlines
Mon, Apr 27 - Sat, May 9
Copa Airlines Logo
7:00 am - 9:08 am
SFO
-
DAV
24h 08m
2 stops
Copa Airlines Logo
9:38 am - 11:40 pm
DAV
-
SFO
16h 02m
1 stop
$1,171Copa Airlines
Wed, Apr 8 - Thu, Apr 16
United Airlines Logo
12:45 am - 9:08 am
SFO
-
DAV
30h 23m
2 stops
United Airlines Logo
10:05 am - 7:16 am
DAV
-
SFO
23h 11m
2 stops
$1,193United Airlines
Booking Insights

KAYAK's insights & trends for San Francisco to Panama flights

Get data-powered insights and trends into flights from San Francisco to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest San Francisco to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from San Francisco found in the last 72 hours was to Panama City, at $385 round-trip. The most popular route is from San Francisco (SFO) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $385.

Can I save money by flying with a layover from San Francisco to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $667, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from San Francisco to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Panama is October, when tickets cost $536 (return) on average. On the other hand, the most expensive months are December and March, when the average cost of round-trip tickets is $841 and $725 respectively.

What’s the cheapest day of the week to fly from San Francisco to Panama?

The average price of all round-trip flights from San Francisco to Panama clicked on KAYAK for each day over the last 12 months.

For San Francisco to Panama, Tuesday is the cheapest day to fly on average and Saturday is the most expensive. Flying from Panama back to San Francisco, the best deals are generally found on Monday, with Thursday being the most expensive.

How far in advance should I book a flight from San Francisco to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Panama, you should book around 6 weeks before departure, which saves you about 8% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 16 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$203
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 28% increase in price.
Flight from San Francisco to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from San Francisco to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Francisco to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Francisco to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Francisco to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $686 on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $755.

Reviews of the top 4 airlines serving from San Francisco to Panama

 
Need help choosing which airline to fly with from San Francisco to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8236 reviews
8.5Crew
7.8Entertainment
7.9Comfort
8.1Boarding
7.2Food
Airline reviews

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

4.0 OkayJahmes, Feb 2026
LAX - MCO
Read more Delta reviews

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The crew, and fellow passengers, were super gracious and kind. There seemed to be plenty of bin space even though the plane was full. It’s nice to get a glass of wine with dinner in Premiere seating, and there was a lot of food.

Everything I mentioned earlier - the airbus was more comfortable indeed and the experience was further enhanced.

The plane was an older model, so it wasn’t as comfortable as others. The flight attendants were not helpful during onboarding. It was a full flight so there was chaos finding space for baggage.

Awesome! On time flight, early arrival, and a complimentary upgrade!

It was nt delta. It was aeromexo. Service was awful. They served a very small drink and NO snack for a 3hr and 35min flight. Then for the first 30 min of the flight is was talk and talk over head interruption the movie/ show i picked to watch.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

The flight was delayed for about 2 hrs. Other than it, it was good.

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

We had turbulence ever 1/2 hr or so and the captains announcements were SOOOO LOUD

it was a very short flight so my expectations were low.

Entertainment kept turning itself off. Gave up on watching a movie.

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

The flight crew where really good. Better then the crew from BNE to SFO

Food should be changed in menu Many muslims travels in this airlime they need to add one Halal meal

left on time, reasonable boarding process arrived early luggage came out quickly

Some flight attendants were great others were cranky. Seats were very tight and sitting on an aisle was very hard as the carts and people walking constantly bumped shoulder and arm.

Pushed back only to get deplaned due to a tire damaged by ground crew. They did at least go pretty fast. The bathrooms should be banned under the Geneva convention. No room to even sit straight on the toilet. The under-seat entertainment units block what little leg room there is.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

Everything you need to know for your flight from San Francisco to Panama

Information on your arrival and departure airports