$233 Find Cheap Flights from San Francisco to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Panama departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from San Francisco to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City1 stop$574
David
David2 stops$1,161
Panama City
Panama City1 stop$574
David
David2 stops$1,161

Book Cheap San Francisco to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Panama

Sat, May 30 - Fri, Jun 5
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
$574Avianca
Fri, May 1 - Thu, Jul 2
Avianca Logo
11:55 pm - 5:00 pm
SFO
-
PTY
15h 05m
2 stops
Avianca Logo
10:10 am - 11:55 pm
PTY
-
SFO
15h 45m
2 stops
$585Avianca
Tue, May 5 - Tue, May 12
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
Avianca Logo
5:30 am - 10:35 pm
PTY
-
SFO
19h 05m
1 stop
$586Avianca
Fri, May 22 - Fri, May 29
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
$587Avianca
Sun, May 24 - Thu, May 28
United Airlines Logo
5:00 am - 8:58 am
SFO
-
DAV
25h 58m
2 stops
United Airlines Logo
9:38 am - 6:30 pm
DAV
-
SFO
34h 52m
2 stops
$1,161United Airlines
Sun, May 24 - Thu, May 28
United Airlines Logo
11:59 pm - 8:58 am
SFO
-
DAV
30h 59m
2 stops
United Airlines Logo
9:38 am - 12:15 am
DAV
-
SFO
16h 37m
2 stops
$1,176United Airlines
Sun, Apr 26 - Wed, May 6
Copa Airlines Logo
1:23 am - 7:38 pm
SFO
-
DAV
16h 15m
1 stop
Copa Airlines Logo
8:18 pm - 6:14 pm
DAV
-
SFO
23h 56m
1 stop
$1,187Copa Airlines
Mon, Apr 27 - Wed, May 6
United Airlines Logo
7:00 am - 9:08 am
SFO
-
DAV
24h 08m
2 stops
United Airlines Logo
9:38 am - 11:59 pm
DAV
-
SFO
16h 21m
2 stops
$1,207United Airlines
Sat, May 2 - Wed, May 6
United Airlines Logo
11:59 pm - 8:58 am
SFO
-
DAV
30h 59m
2 stops
United Airlines Logo
9:38 am - 5:12 pm
DAV
-
SFO
33h 34m
2 stops
$1,227United Airlines
Sun, Apr 26 - Wed, May 6
Copa Airlines Logo
1:23 am - 7:38 pm
SFO
-
DAV
16h 15m
1 stop
Copa Airlines Logo
9:38 am - 11:40 pm
DAV
-
SFO
16h 02m
1 stop
$1,231Copa Airlines
Booking Insights

KAYAK's insights & trends for San Francisco to Panama flights

Get data-powered insights and trends into flights from San Francisco to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest San Francisco to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from San Francisco found in the last 72 hours was to Panama City, at $389 round-trip. The most popular route is from San Francisco (SFO) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $389.

What is the cheapest time of day to fly to Panama?

The average price for all round-trip flights from San Francisco to Panama depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $691 on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $717.

Can I save money by flying with a layover from San Francisco to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $667, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from San Francisco to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Panama is October, when tickets cost $533 (return) on average. On the other hand, the most expensive months are December and March, when the average cost of round-trip tickets is $839 and $674 respectively.

What’s the cheapest day of the week to fly from San Francisco to Panama?

The average price of all round-trip flights from San Francisco to Panama clicked on KAYAK for each day over the last 12 months.

For San Francisco to Panama, Monday is the cheapest day to fly on average and Saturday is the most expensive. Flying from Panama back to San Francisco, the best deals are generally found on Saturday, with Sunday being the most expensive.

How far in advance should I book a flight from San Francisco to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Panama, you should book around 8 weeks before departure, which saves you about 22% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 16 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$233
Best time to beat the crowds with an average 5% drop in price.
Most popular time to fly with an average 27% increase in price.
Flight from San Francisco to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from San Francisco to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Francisco to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Francisco to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Francisco to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from San Francisco to Panama

 
Need help choosing which airline to fly with from San Francisco to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8398 reviews
8.1Boarding
8.5Crew
7.2Food
7.8Entertainment
7.9Comfort
Airline reviews

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

10.0 ExcellentSarah, Apr 2026
LAX - SFO
Read more Delta reviews

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

N Everything was perfect from boarding to assistance to baggage in Tampa

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

Fast, lovely scenery, great info on the Delta flight screen about landmarks we were flying over. Great landing!

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I took seat 15A in anticipation of window seat, there is no window.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Boarding was again a "free for all". We were boarding group 4, and almost the entire plane was able to board before us. It's a shame that someone who follows the rules, gets the short end of the stick. Not fair.

It was perfect! I've never flown with United before, but I definitely will in the future

the entire flight felt off. The crew seemed uninterested and disengaged. The food service was really bad - overcooked, bland, weird food service. They actually woke us up to serve chicken wraps in the middle of the night, after dinner and before breakfast. Made no sense. Ultimately, I was glad they did though, because the breakfast had been held for so long it was inedible. Eggs, potatoes, sausage - all disgusting. We were asked to "honor" the lavatories for premium customers and stay in our own cabin: this was also strange. So people in economy didn't pay enough to use the closest toilet to them??? It's a toilet. All in all, not the experience I have come to expect from United Airlines. The return flight from Paris to SFO was better, btw.

They delayed the flight from 9:00 to 11:55 At 11:45 they canceled the flight. I paid a premium price for the tickets with poor service

The 777’s economy seat’s legroom was more tolerable than expected. I appreciate the reclining mechanism which slides the seat forward to minimize cannibalizing the space behind. The food was terrible: very salty.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

Staff were good. My seat was in need of repair, but for a short flight was not problematic. Usual basic snack and drink setup that you'll find on any US carrier. Over, a decent, basic flight.

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

We had turbulence ever 1/2 hr or so and the captains announcements were SOOOO LOUD

it was a very short flight so my expectations were low.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Everything you need to know for your flight from San Francisco to Panama

Information on your arrival and departure airports