Find Deals on Flights from San Francisco to Central America

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
Students
under 26
The price shown for each flight will be the average for all passengers including any infants.
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Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from San Francisco to Central America

(Round-trip)
Depart: Thu Mar 9 2017 Return: Mon Mar 13 2017 Trip spans 4 days
Aeromexico
Aeromexico
SFO
PTY
11h 44m
1 stop
PTY
SFO
22h 52m
1 stop
Depart: Sun Jan 15 2017 Return: Sun Jan 22 2017 Trip spans 8 days
Major Airline
Major Airline
SFO
PTY
15h 49m
1 stop
PTY
SFO
17h 53m
1 stop
Depart: Fri Jan 27 2017 Return: Tue Jan 31 2017 Trip spans 5 days
Delta
Delta
SFO
PTY
9h 44m
1 stop
PTY
SFO
13h 41m
1 stop
Depart: Sat Mar 4 2017 Return: Thu Mar 9 2017 Trip spans 6 days
JetBlue
JetBlue
SFO
SJO
14h 14m
1 stop
SJO
SFO
11h 25m
1 stop
Depart: Wed Jun 28 2017 Return: Sun Jul 16 2017 Trip spans 19 days
Copa Airlines
Copa Airlines
SFO
GUA
14h 47m
1 stop
GUA
SFO
18h 50m
2 stops
Depart: Mon Jan 9 2017 Return: Thu Jan 12 2017 Trip spans 4 days
United
United
SFO
BZE
10h 45m
2 stops
BZE
SFO
18h 57m
2 stops
Depart: Wed Mar 8 2017 Return: Tue Mar 28 2017 Trip spans 20 days
American Airlines
American Airlines
SFO
TGU
9h 20m
1 stop
TGU
SFO
12h 52m
1 stop
Depart: Sun Jun 11 2017 Return: Thu Jun 29 2017 Trip spans 19 days
Avianca
Avianca
SFO
SAL
5h 25m
nonstop
SAL
SFO
6h 05m
nonstop
Depart: Fri Feb 10 2017 Return: Sun Feb 19 2017 Trip spans 10 days
Major Airline
Major Airline
SFO
PTY
12h 00m
1 stop
PTY
SFO
17h 53m
1 stop
Depart: Tue Feb 28 2017 Return: Wed Apr 19 2017 Trip spans 50 days
Delta
Delta
SFO
PTY
19h 46m
1 stop
PTY
SFO
13h 50m
1 stop
Depart: Fri Mar 3 2017 Return: Sat Mar 11 2017 Trip spans 9 days
Aeromexico
Aeromexico
SFO
PTY
11h 44m
1 stop
PTY
SFO
22h 52m
1 stop
Depart: Sun Apr 23 2017 Return: Wed Apr 26 2017 Trip spans 4 days
JetBlue
JetBlue
SFO
SJO
14h 14m
1 stop
SJO
SFO
11h 25m
1 stop
Depart: Mon Apr 17 2017 Return: Tue Apr 25 2017 Trip spans 9 days
Delta
Delta
SFO
PTY
13h 15m
1 stop
PTY
SFO
12h 39m
1 stop
Depart: Sun Mar 12 2017 Return: Sun Mar 26 2017 Trip spans 14 days
Major Airline
Major Airline
SFO
LIR
19h 59m
2 stops
LIR
SFO
11h 05m
2 stops
Depart: Sun May 7 2017 Return: Wed May 17 2017 Trip spans 11 days
Delta
Delta
SFO
PTY
11h 45m
1 stop
PTY
SFO
13h 51m
1 stop
Depart: Thu Feb 23 2017 Return: Thu Mar 23 2017 Trip spans 28 days
JetBlue
JetBlue
SFO
SJO
12h 01m
1 stop
SJO
SFO
11h 25m
1 stop
Depart: Mon Jun 12 2017 Return: Tue Jun 20 2017 Trip spans 9 days
Aeromexico
Aeromexico
SFO
PTY
15h 52m
2 stops
PTY
SFO
32h 15m
2 stops
Depart: Tue Jun 6 2017 Return: Tue Jul 4 2017 Trip spans 29 days
Copa Airlines
Copa Airlines
SFO
GUA
23h 54m
2 stops
GUA
SFO
24h 02m
1 stop
Depart: Sat Dec 10 2016 Return: Tue Dec 13 2016 Trip spans 4 days
Delta
Delta
SFO
PTY
29h 33m
1 stop
PTY
SFO
11h 44m
1 stop
Depart: Mon Mar 13 2017 Return: Thu Mar 23 2017 Trip spans 11 days
Major Airline
Major Airline
SFO
LIR
26h 45m
1 stop
LIR
SFO
18h 32m
2 stops
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

We attempt to get accurate prices, however, prices are not guaranteed.

Here's why:

We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

We compile tonnes of data for you
Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

If you have more questions or if you have a bad price to report to us,
please send us an email and someone from our team will get back to you promptly.

Airports
Origin

San Francisco
$359
Destination

Guatemala City
$480
Liberia
$408
Panama City
$359
Tegucigalpa
$643
San Salvador
$664
Belize City
$509
San Jose
$403