$262 Find Cheap Flights from Panama to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
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Cheap Flights from Panama to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Panama to San Francisco

KAYAK's recommended round-trip deals from the most popular airlines that fly from Panama to San Francisco.
Discover the best prices for you by selecting your travel dates on KAYAK.
Avianca Logo
9:50 am - 10:45 pmPTY-SFO
14h 55m2 stops
Avianca Logo
12:05 am - 2:45 pmSFO-PTY
12h 40m1 stop
$466Avianca
Find Deal
Thu, May 22 - Sun, May 25
Avianca Logo
3:20 am - 10:45 pmPTY-SFO
21h 25m2 stops
Avianca Logo
2:20 pm - 10:10 amSFO-PTY
17h 50m2 stops
$476Avianca
Find Deal
Wed, May 21 - Tue, May 27
Avianca Logo
3:25 am - 11:55 pmPTY-SFO
22h 30m2 stops
Avianca Logo
2:20 pm - 2:45 pmSFO-PTY
22h 25m1 stop
$483Avianca
Find Deal
Mon, Jun 23 - Thu, Jul 3
Copa Airlines Logo
5:50 pm - 11:40 pmPTY-SFO
7h 50mnonstop
Copa Airlines Logo
1:37 am - 10:41 amSFO-PTY
7h 04mnonstop
$507Copa Airlines
Find Deal
Tue, Jun 24 - Wed, Jul 2
Delta Logo
2:14 pm - 12:46 amPTY-SFO
12h 32m1 stop
Delta Logo
9:30 pm - 12:49 pmSFO-PTY
13h 19m1 stop
$512Delta
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Fri, Sep 12 - Wed, Sep 24
United Airlines Logo
3:35 pm - 9:15 pmPTY-SFO
7h 40mnonstop
United Airlines Logo
10:55 am - 8:10 pmSFO-PTY
7h 15mnonstop
$534United Airlines
Find Deal
Sun, Jun 8 - Thu, Jun 26
United Airlines Logo
3:35 pm - 9:15 pmPTY-SFO
7h 40mnonstop
United Airlines Logo
6:55 pm - 4:12 pmSFO-PTY
19h 17m1 stop
$539United Airlines
Find Deal
Sun, Jun 8 - Thu, Jun 26
Copa Airlines Logo
5:50 pm - 11:40 pmPTY-SFO
7h 50mnonstop
Copa Airlines Logo
1:37 am - 10:41 amSFO-PTY
7h 04mnonstop
$578Copa Airlines
Find Deal
Thu, Jun 12 - Fri, Jul 11
American Airlines Logo
3:20 pm - 8:36 amPTY-SFO
19h 16m2 stops
American Airlines Logo
11:48 pm - 12:25 pmSFO-PTY
10h 37m1 stop
$589American Airlines
Find Deal
Fri, Jun 27 - Mon, Sep 15
American Airlines Logo
1:50 pm - 8:53 amPTY-SFO
21h 03m2 stops
American Airlines Logo
1:24 pm - 1:20 pmSFO-PTY
20h 56m1 stop
$602American Airlines
Find Deal
Wed, Oct 8 - Wed, Nov 19
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KAYAK's insights & trends for flights to San Francisco

Get data-powered insights and trends for flights to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Francisco is August, where tickets cost $582 on average for return flights. On the other hand, the most expensive months are March and April, where the average cost of tickets from Panama is $685 and $665 respectively. For one-way flights, the best month to travel is August with an average price of $582.

What is a good deal for flights to San Francisco?

If you’re looking for cheap airfare to San Francisco, 25% of our users found tickets to San Francisco for the following prices or less: From Panama City $574 round-trip.

How far in advance should I book a flight to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price, you should book around 6 weeks before departure. For the absolute cheapest price, our data suggests you should book 20 weeks before departure.


Good to know

Low seasonAugust
High seasonOctober
Cheapest flight$262
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 4% increase in price.
Flight from Panama City to San Francisco

FAQs - booking San Francisco flights

  • How far is San Francisco Airport from central San Francisco?

    You’ll need to travel 12 miles to reach the San Francisco city center from San Francisco Airport.

  • What is the name of San Francisco’s airport?

    San Francisco is served by San Francisco Airport, also commonly referred to as San Francisco or San Francisco Intl. The airport code is SFO.

  • How much is a flight to San Francisco?

    On average, a flight to San Francisco costs $973. The cheapest price found on KAYAK in the last 2 weeks cost $372 and departed from Panama City Tocumen Intl Airport.

  • What is the cheapest day to fly to San Francisco?

    Based on KAYAK data, the cheapest day to fly to San Francisco is Monday where round-trip tickets can be as cheap as $634. On the other hand, the most expensive day to fly is Tuesday, where round-trip prices are $780 on average.

  • How does KAYAK find such low prices on flights to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to San Francisco?

    The cheapest time of day to fly to San Francisco is generally at night, when round-trip flights cost $433 on average. The most expensive time of day to fly to San Francisco is generally in the evening, which is peak travel time and where the average cost of a ticket is $670.

  • How many direct flights to San Francisco are there each week?

    Each week there are around 4,087 direct flights from within Panama to San Francisco. The most common day for departures is Monday, with 15% of flights taking off on this day.

Top tips for finding cheap flights to San Francisco

  • Looking for cheap airfare to San Francisco? 25% of our users found round-trip tickets to San Francisco for the following prices or less: From Panama City $452
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Francisco flight deals.

Top 3 airlines serving from Panama to San Francisco

 
See real verified KAYAK customer reviews for airlines flying to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Francisco. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1418 reviews
8.1Crew
7.8Boarding
7.4Comfort
6.8Food
6.8Entertainment
Airline reviews

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

2.0 MediocreCec, Apr 2025PTY - IAD
Read more Copa Airlines reviews

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

No headphones given for inflight entertainment. I missed my flight from the previous day and the customer service agent tried to extort an additional $100.00 US from me for missing my flight. Really?!

It was reasonably comfortable trip considering its duration (7 hours). Crew was very good and friendly, seats very more comfortable than other planes. Only negative comment would be that the bathroom light did not get its full brightness 🙃

Friendly flight team and seamless travel from one stop to next.

I loved my experience. Very safe, Very informative and very friendly.

At JFK the Security line was extremely long and few checkpoints open.

Check in person said there would be lunch. We were first class passengers and lunch was chips.

Flight attendant -José? - was over the top friendly and professional. Beautiful new plane with lie flat seats in Business (worth it!)

Horrible food. No wine or any other alcohol is served on the flight. Water is not served often and they refused when I asked for water in two cups. On the other hand, both going and coming back flights were on time.

I needed to make changes to my flights. When I called customer service, they assisted me with care professionalism.

A bit rush for transit. Food and entertainment are not available

The gate was too far away for the connecting flight

Generally good. The aisles have gotten narrower which can slow down boarding. Flight crew was great! Healthier complimentary snacks would be appreciated. Due to earthquake in San Francisco we had to circle in air space for a bit but then had a smooth landing. I laud the flight crew for their patience ;)

headphone jack didnt work for the first flight and not much variety

The agents was very rude and they charged me $50 for a carry-on bag saying that it was too big and then I saw someone going on a plane with the same size bag as me

For the most part united was a good experience, how ever when they came by with the snacks and water, they completely passed by my wife and I. As we were in separate rows. On a 5 hr flight we were not offered water

Fantastic crew. Flight was delayed at last minute but we were given updates every 20 minutes and the crew was so friendly and considerate. I miss the touch screens on the back of the seats, wish they would bring that back though.

Beijing PEK to SFO. I had an economy seat on this flight. The seat comfort was acceptable. My main complaint is with the FA’s lack of personality and absence from servicing the plane, specifically restroom care (I wish I could share a pic of the restroom that I captured) and care of travelers—drink cart/availability of drinks. I'm amazed at the level of service on other International travel where a passenger is most often appreciated.

Awful. Worst airline I have ever been on. Crew were among the rudest people I have ever dealt with. United staff members were rude and disrespectful. My flight was delayed, causing me to miss a connecting flight. I understand things happen, but when staff start lying about what actually happened, that is when I have an issue. Just be honest, really it isn’t that hard. I’m being very honest with this review and I don’t find this difficult what so ever. In fact, because of United Airlines, my Christmas holiday was off to a really rocky start. As someone who has traveled across the world, it has only been United that I have had a truly awful experience.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

A few years ago long flights 6 hours or so used to have video screens and they offered ear phones. The food cart used to come and drinks. Now absolutely nothing. Avianca is as bad as Spirit Airlines. Avianca will now be my last choice when booking my next flight.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

There isn't much space in-between seats and even water needs to be paid for during the flight.

Boarding was somewhat confusing in that the wrong messages were being displayed at the gate. It was somewhat annoying that I got off one flight and straight onto another (from the same gate), but in between they re-checked my hand luggage and made me get rid of my water (which they charge for on the plane). I was sitting in their 'Plus' seating, but the leg room was still too small to be able to sit square. The food options on the flights are pretty cheap quality (but not price). They got me from 'A' to 'B' on-time and for a relatively good price, but the experience itself was below average.

Lounge for business was closed. Boarding was rush and stand by. Seat for business is just the middle seat blocked and some more leg room.

I paid over $200 for seat selection for these flights and I was still stuck on long international flights in seats that do not recline and do not have the head support cushion. At this point basically all airlines have those for all seats, and this really took me by surprise and made me not ever want to travel on Avianca. The Kayak agent who called me for the seat selection (Donovan) was courteous, but it seems the system for this doesn't work. I was offered seat selection, for the $200+, but without being able to see what I was selecting, with no guarantee where I'd be...and then I still ended up in terrible seats. On my way to, and especially after, a very intense business trip, the seat situation really soured my experience.

Overpriced checked bag price of $120 and they charge you for carryon if the size is not minimal of $120.

Be very careful of the initial low price because Avianca wil bill you for a carryon of $120 or a checked bag for $120. Also, be careful with connections because the customs entry process is slow and the connecting terminal is not close.

My whole return flight itinerary, 3 flights, got canceled without any warning to me because I missed one of the earlier flights 3 weeks ago

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