$355 Find Cheap Flights from Panama to San Francisco - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Panama to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Francisco

Tue, Aug 25 - Tue, Sep 1
Multiple Airlines Logo
3:10 pm - 11:34 am
PTY
-
SFO
22h 24m
3 stops
Multiple Airlines Logo
5:35 pm - 9:15 am
SFO
-
PTY
37h 40m
3 stops
$637Multiple Airlines
Tue, Aug 25 - Tue, Sep 1
Multiple Airlines Logo
3:10 pm - 11:34 am
PTY
-
SFO
22h 24m
3 stops
Multiple Airlines Logo
5:35 pm - 9:15 am
SFO
-
PTY
37h 40m
3 stops
$638Multiple Airlines
Fri, Sep 11 - Fri, Sep 25
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
$693Avianca
Thu, Aug 27 - Tue, Sep 1
Avianca Logo
10:10 am - 11:55 pm
PTY
-
SFO
15h 45m
2 stops
Avianca Logo
2:30 am - 1:55 am
SFO
-
PTY
21h 25m
1 stop
$694Avianca
Thu, Aug 13 - Sat, Aug 22
Avianca Logo
10:10 am - 10:35 pm
PTY
-
SFO
14h 25m
2 stops
Avianca Logo
2:30 am - 1:55 am
SFO
-
PTY
21h 25m
1 stop
$695Avianca
Tue, Aug 25 - Tue, Sep 1
Avianca Logo
5:30 am - 10:35 pm
PTY
-
SFO
19h 05m
1 stop
Avianca Logo
2:15 pm - 10:30 am
SFO
-
PTY
18h 15m
1 stop
$703Avianca
Mon, Jul 20 - Sat, Jul 25
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
11:55 pm - 5:00 pm
SFO
-
PTY
15h 05m
2 stops
$704Avianca
Fri, Aug 14 - Mon, Aug 24
Avianca Logo
5:30 am - 10:35 pm
PTY
-
SFO
19h 05m
1 stop
Avianca Logo
7:45 am - 1:55 am
SFO
-
PTY
16h 10m
2 stops
$713Avianca
Fri, Aug 14 - Mon, Aug 24
Avianca Logo
10:10 am - 6:25 am
PTY
-
SFO
22h 15m
3 stops
Avianca Logo
7:45 am - 1:55 am
SFO
-
PTY
16h 10m
2 stops
$744Avianca
Tue, Aug 4 - Wed, Aug 19
Avianca Logo
3:50 pm - 12:50 pm
PTY
-
SFO
23h 00m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$755Avianca
Booking Insights

KAYAK's insights & trends for flights to San Francisco

Get data-powered insights and trends for flights to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest day to fly to San Francisco?

The average price of all round-trip flights to San Francisco clicked on KAYAK for each day over the last 12 months.

Based on KAYAK data, the cheapest day to fly to San Francisco is Friday where round-trip tickets can be as cheap as $653. On the other hand, the most expensive day to fly is Sunday, where round-trip prices are $1,248 on average.

What is the cheapest month to fly to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Francisco is April, where tickets cost $153 on average for return flights. On the other hand, the most expensive months are November and August, where the average cost of tickets from Panama is $487 and $477 respectively. For one-way flights, the best month to travel is December with an average price of $234.

What is the cheapest time of day to fly to San Francisco?

The average price for all round-trip flights to San Francisco depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to San Francisco is generally in the morning, when round-trip flights cost $752 on average. The most expensive time of day to fly to San Francisco is generally in the evening, which is peak travel time and where the average cost of a ticket is $775.

How far in advance should I book a flight to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price, you should book around 6 weeks before departure, which saves you about 21% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonMarch
Cheapest flight$355
Best time to beat the crowds but there is an average 9% increase in price.
Flight from Panama City to San Francisco

FAQs - booking San Francisco flights

  • How far is San Francisco Airport from central San Francisco?

    You’ll need to travel 11 miles to reach the San Francisco city center from San Francisco Airport.

  • What is the name of San Francisco’s airport?

    San Francisco is served by San Francisco Airport, also commonly referred to as San Francisco or San Francisco Intl. The airport code is SFO.

  • How much is a flight to San Francisco?

    On average, a flight to San Francisco costs $871. The cheapest price found on KAYAK in the last 2 weeks cost $758 and departed from Panama City Tocumen Intl Airport.

  • How does KAYAK find such low prices on flights to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to San Francisco

  • Looking for cheap airfare to San Francisco? 25% of our users found round-trip tickets to San Francisco for the following prices or less: From Panama City $1,301
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Francisco flight deals.

Reviews of the top 3 airlines serving from Panama to San Francisco

 
See real verified KAYAK customer reviews for airlines flying to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Francisco. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1566 reviews
7.4Comfort
6.8Entertainment
8.1Crew
7.8Boarding
6.9Food
Airline reviews

stood in line to check in luggage for nearly an hour. very poor service and not excusable

4.0 OkayAnonymous, Jun 2026
PTY - AUS
Read more Copa Airlines reviews

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Some of the Air hostesses are not that friendly. Need improvement

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

Horrible food. No wine or any other alcohol is served on the flight. Water is not served often and they refused when I asked for water in two cups. On the other hand, both going and coming back flights were on time.

it was great! Boarded on-time, reasonable leg room, pleasant staff, decent food. The only thing is we were directed to Terminal 2 when the gate was actually in Terminal 1. Smooth ride. Landed early. Got off plane easily and quickly.

Excellent flight. On time. Great staff. Clean and crisp cabin.

The Manila airport was under renovation so there was no business class lounge. The double security check was disorganized and the flight attendants were grouchy.

Flight attendants on United are the worst in the business. Can’t be bothered to provide even basic levels of service and are as rude as anyone can get. This flight was not an exception to that rule.

United has been holding my money for a cancel on another ticket they wouldn’t let me fly for going on 5 months. Terrible service I wouldn’t choose to buy tickets or fly with united again. Very bad experience generally dishonorable and poor service .

The flight got delayed. They forgot to bring the drinks when I asked for it. The toilet is messy.

This was an overnight flight, and in the morning they did know coffee service. How you can throw passengers in a San Francisco airport at 5:40 a.m. in the morning and not giving them Coffee is a crime.

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

The staff was extremely helpful and friendly at all times! They went above and beyond to get us into an earlier flight in San Diego to make our connection in SFO possible, because our original flight did actually not make it! I did so much appreciate the UA team and how they made this possible. We also didn’t have seats together on the long flight to Singapore, but they found us seats together last moment with no additional cost! Nobody sat next to us, so that we were able to sleep! Thanks to UA for improving their service and Underpricer for booking this trip! Please be careful: 1,5 hrs for transfer in San Francisco might not be enough time in the future

Crew was great! Good meals. Had room to stretch out

How can you rate a flight when it is canceled after you leave the gate & 3 hours into sitting there or in remote area of airport after mechanical problems

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

The fees for baggage were outrageous. $130 for carry on and $150 for check in for an international flight. The seats did not recline. We were not even offered water. Had we known all of this, we would not have booked Avianca at all.

I was shocked flying to El Salvador that they only give you water. Everything else you have to pay for. There is no wifi or entertainment and it’s an international flight. At least back in the day they had tvs on the plane and everyone watched the same movie. Also seats do not recline, even comfort or plus.

I did not like anything, first time I use company and for sure it will be the last time, they charge for simple operations that any other average airline wouldn't charge.

The good thing is the flight was on time and the crew was really nice. They can work better the arriving with staff

The inflight entertainment did not work on a 6 hour flight The cel phone chargers did not work There was a 45 minute wait for the luggage to get off the plane.

They could offer free food and drink like other international flights.

Flight attendants to show up on time, offer drinks and food.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Calistoga
Rohnert Park
Marina
Emeryville
Pacifica
Capitola
Millbrae
Newark
Campbell
Novato
Mill Valley
Windsor
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West Sacramento
Belmont
Richmond
American Canyon
Corte Madera
Jenner
Los Altos

Everything you need to know for your flight to San Francisco

Information on the airport you'll fly into in San Francisco