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Cheap Flights from Panama to San Francisco

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Francisco

Mon, Oct 12 - Sat, Oct 24
Avianca Logo
10:10 am - 10:35 pmPTY  Panama City Tocumen Intl-SFO San Francisco
14h 25m2 stops Bogotá El Dorado San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 3:15 pmSFO  San Francisco-PTY Panama City Tocumen Intl
13h 20m2 stops San Salvador El Salvador Intl Bogotá El Dorado
$693Avianca
Wed, Feb 3 - Wed, Feb 17
Avianca Logo
5:30 am - 11:55 amPTY  Panama City Tocumen Intl-SFO San Francisco
9h 25m1 stop San Salvador El Salvador Intl
Avianca Logo
1:15 pm - 10:35 amSFO  San Francisco-PTY Panama City Tocumen Intl
18h 20m1 stop San Salvador El Salvador Intl
$693Avianca
Fri, Sep 11 - Fri, Sep 25
Avianca Logo
5:30 am - 12:50 pmPTY  Panama City Tocumen Intl-SFO San Francisco
9h 20m1 stop San Salvador El Salvador Intl
Avianca Logo
11:55 pm - 10:30 amSFO  San Francisco-PTY Panama City Tocumen Intl
8h 35m1 stop San Salvador El Salvador Intl
$693Avianca
Sat, Oct 17 - Fri, Oct 30
Copa Airlines Logo
6:08 pm - 11:40 pmPTY  Panama City Tocumen Intl-SFO San Francisco
7h 32mnonstop
Copa Airlines Logo
1:31 am - 10:46 amSFO  San Francisco-PTY Panama City Tocumen Intl
7h 15mnonstop
$859Copa Airlines
Wed, Feb 3 - Tue, Feb 16
Copa Airlines Logo
12:38 pm - 5:25 pmPTY  Panama City Tocumen Intl-SFO San Francisco
7h 47mnonstop
Copa Airlines Logo
12:42 am - 10:46 amSFO  San Francisco-PTY Panama City Tocumen Intl
7h 04mnonstop
$859Copa Airlines
Mon, Nov 16 - Tue, Nov 24
Copa Airlines Logo
6:31 pm - 11:12 pmPTY  Panama City Tocumen Intl-SFO San Francisco
7h 41mnonstop
Copa Airlines Logo
7:36 pm - 5:46 amSFO  San Francisco-PTY Panama City Tocumen Intl
7h 10mnonstop
$859Copa Airlines
Thu, Jan 14 - Wed, Jan 27
United Airlines Logo
4:41 pm - 7:20 amPTY  Panama City Tocumen Intl-SFO San Francisco
17h 39m1 stop Houston George Bush Intcntl
United Airlines Logo
12:45 am - 7:38 pmSFO  San Francisco-PTY Panama City Tocumen Intl
15h 53m1 stop Houston George Bush Intcntl
$864United Airlines
Fri, Dec 4 - Tue, Dec 8
United Airlines Logo
11:35 am - 8:10 pmPTY  Panama City Tocumen Intl-SFO San Francisco
11h 35m1 stop Houston George Bush Intcntl
United Airlines Logo
6:40 pm - 5:12 pmSFO  San Francisco-PTY Panama City Tocumen Intl
19h 32m2 stops Chicago O'Hare Intl Houston George Bush Intcntl
$864United Airlines
Sat, Dec 19 - Sat, Jan 2
Delta Logo
3:25 pm - 11:58 pmPTY  Panama City Tocumen Intl-SFO San Francisco
11h 33m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 8:00 pmSFO  San Francisco-PTY Panama City Tocumen Intl
11h 00m1 stop Atlanta Hartsfield-Jackson
$864Delta
Sat, Dec 19 - Sat, Jan 2
Delta Logo
3:25 pm - 11:58 pmPTY  Panama City Tocumen Intl-SFO San Francisco
11h 33m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 8:00 pmSFO  San Francisco-PTY Panama City Tocumen Intl
11h 00m1 stop Atlanta Hartsfield-Jackson
$872Delta
Booking Insights

KAYAK's insights & trends for flights to San Francisco

Get data-powered insights and trends for flights to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest day to fly to San Francisco?

Based on KAYAK data, the cheapest day to fly to San Francisco is Friday where round-trip tickets can be as cheap as $649. On the other hand, the most expensive day to fly is Sunday, where round-trip prices are $1,248 on average.

What is the cheapest month to fly to San Francisco?

The cheapest month for flights to San Francisco is April, where tickets cost $612 on average for return flights. On the other hand, the most expensive months are February and March, where the average cost of tickets from Panama is $793 and $780 respectively. For one-way flights, the best month to travel is October with an average price of $289.

What is the cheapest time of day to fly to San Francisco?

The cheapest time of day to fly to San Francisco is generally in the morning, when round-trip flights cost $683 on average. The most expensive time of day to fly to San Francisco is generally in the evening, which is peak travel time and where the average cost of a ticket is $778.

What is a good deal for flights to San Francisco?

If you’re looking for cheap airfare to San Francisco, 25% of our users found tickets to San Francisco for the following prices or less: From Panama City $454 round-trip.

How far in advance should I book a flight to San Francisco?

To get a below average price, you should book around 6 weeks before departure, which saves you about 19% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low season

March

Cheapest flight

$443
Best time to beat the crowds but there is an average 6% increase in price.
Most popular time to fly with an average 4% increase in price.
Flight from Panama City to San Francisco

FAQs - booking San Francisco flights

  • How far is San Francisco Airport from central San Francisco?

    You’ll need to travel 11 miles to reach the San Francisco city center from San Francisco Airport.

  • What is the name of San Francisco’s airport?

    San Francisco is served by San Francisco Airport, also commonly referred to as San Francisco or San Francisco Intl. The airport code is SFO.

  • How much is a flight to San Francisco?

    On average, a flight to San Francisco costs $1,121. The cheapest price found on KAYAK in the last 2 weeks cost $454 and departed from Panama City Tocumen Intl Airport.

  • How does KAYAK find such low prices on flights to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to San Francisco

  • Looking for cheap airfare to San Francisco? 25% of our users found round-trip tickets to San Francisco for the following prices or less: From Panama City $499
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Francisco flight deals.

Reviews of the top 3 airlines serving from Panama to San Francisco

 
Need help choosing which airline to fly with to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1552 reviews
6.9Food
8.1Crew
6.8Entertainment
7.8Boarding
7.4Comfort
Airline reviews

Flight Crew Review The crew was absolutely amazing from start to finish! They were friendly, professional, attentive, and genuinely made the flight feel comfortable and enjoyable. Every interaction was pleasant, and they went above and beyond to make sure passengers were taken care of. You could really tell that they cared about providing great service. I truly appreciate their kindness and professionalism and would be happy to fly with this crew again!

10.0 ExcellentAnonymous, Aug 2026
Read more Copa Airlines reviews

Flight Crew Review The crew was absolutely amazing from start to finish! They were friendly, professional, attentive, and genuinely made the flight feel comfortable and enjoyable. Every interaction was pleasant, and they went above and beyond to make sure passengers were taken care of. You could really tell that they cared about providing great service. I truly appreciate their kindness and professionalism and would be happy to fly with this crew again!

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

Horrible food. No wine or any other alcohol is served on the flight. Water is not served often and they refused when I asked for water in two cups. On the other hand, both going and coming back flights were on time.

it was great! Boarded on-time, reasonable leg room, pleasant staff, decent food. The only thing is we were directed to Terminal 2 when the gate was actually in Terminal 1. Smooth ride. Landed early. Got off plane easily and quickly.

This flight did not take place because the passenger was in the hospital. We have made so many attempts to rebook this flight and have spoken to so many United Airlines representatives and everyone is giving you a different answer. It has become beyond frustrating to the point where we now have to seek legal help. This is a family of 4 so a lot of money was spent to purchase 4 tickets to go visit their daughter/sister who is a US servicewoman in Okinawa and to be treated with such disdain and disrespect is beyond reprehensible. The main traveler was given sent a letter by United confirming a refund on the tickets and to be able to use them but every attempt to use this has been met with a negative response so much so that the client is over stressed.

The pre-order only approach for fresh food is really challenging

the seat has a problem. the back had a hole.

The entire experience convinced my wife, Cathy, and me that traveling Polaris on United is the only way we’ll fly in the future. From check-in and baggage drop to the end of the 12-hour flight, the customer service was exceptional, with numerous staff members exemplifying the very best in care. On board, Andre, our primary crew chief, was sincerely friendly, a consummate professional, and, along with Freddy, one of his team members, truly among the best of the best. The captain even came through the cabin to chat with passengers—a wonderful personal touch, especially on such a long journey.

The SFO lounge closes at 12 midnight. My flight took off at 2AM

Flight be on time would be a good start. Then train your flight attendants to be attentive and friendly. This time they completely forgot my row for the measly snack! United, do better!

We boarded the plane and were about to take off when we were notified that the tires had to be checked. Upon inspection, they were found to need replacement, so the entire plane had to be deboarded. After we exited the plane, United staff forced us to stay in the gate area by posting "Do Not Exit" signs on the doors connecting the gate area to the terminal. Many of us had already rebooked our flights and had no checked bags, but they told us we could not leave. This seemed inappropriate to hold people under false pretenses. When the agent told us we could leave, I asked them to please take down the "Do Not Exit" signs, as they were misleading. The agent refused, and I told them that it didn't feel right to hold people like that.

There was a piece of plastic baked into my buttermilk biscuit! I have a pictures. The flight attendants in first class were really apologetic, and tried to rectify the situation. I I am very appreciative that they were able to give me some packets of pretzels and gummy bears. I understand they don't personally handle the food until warming it up so I know it wasn't their fault. I don't know whether it was a newer aircraft, or different food packaging, but I was happy that when the food was being warmed up - it didn't smell like plastic. Jokes on me with finding plastic in my food.

United was excellent. We had very good experience flying the carrier. Certainly. We will opt to fly them for sure. Lufthansa is out.

The seat that I got this time is really good.

Better seats, allow us to upgrade, terrible website, poor telephone service, better equipment

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

The fees for baggage were outrageous. $130 for carry on and $150 for check in for an international flight. The seats did not recline. We were not even offered water. Had we known all of this, we would not have booked Avianca at all.

I was shocked flying to El Salvador that they only give you water. Everything else you have to pay for. There is no wifi or entertainment and it’s an international flight. At least back in the day they had tvs on the plane and everyone watched the same movie. Also seats do not recline, even comfort or plus.

I did not like anything, first time I use company and for sure it will be the last time, they charge for simple operations that any other average airline wouldn't charge.

The good thing is the flight was on time and the crew was really nice. They can work better the arriving with staff

The inflight entertainment did not work on a 6 hour flight The cel phone chargers did not work There was a 45 minute wait for the luggage to get off the plane.

They could offer free food and drink like other international flights.

Flight attendants to show up on time, offer drinks and food.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
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Everything you need to know for your flight to San Francisco

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