$277 Find Cheap Flights from Panama to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$494
Overall average: $711
Avianca
Wed 2/4Tue 2/10
PTY - SFO • 2 stops
Cheapest non-stop
$650
Typical prices: $685-$827
Copa Airlines
Fri 3/6Sun 3/8
PTY - SFO • Non-stop
When to travel
August
Cheapest • 21% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Francisco

Wed, Feb 4 - Tue, Feb 10
Avianca Logo
2:55 am - 9:50 pm
PTY
-
SFO
21h 55m2 stops
Avianca Logo
11:10 pm - 12:40 am
SFO
-
PTY
22h 30m2 stops
$494Avianca
Thu, Feb 5 - Tue, Feb 10
Avianca Logo
3:50 pm - 11:20 pm
PTY
-
SFO
10h 30m1 stop
Avianca Logo
11:10 pm - 10:30 am
SFO
-
PTY
8h 20m1 stop
$501Avianca
Wed, Feb 4 - Tue, Feb 10
Avianca Logo
2:55 am - 9:50 pm
PTY
-
SFO
21h 55m2 stops
Avianca Logo
11:10 pm - 10:30 am
SFO
-
PTY
8h 20m1 stop
$503Avianca
Mon, Mar 23 - Mon, Mar 30
Avianca Logo
7:50 pm - 1:00 pm
PTY
-
SFO
19h 10m1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m1 stop
$506Avianca
Mon, Mar 23 - Mon, Mar 30
Avianca Logo
2:55 pm - 1:00 pm
PTY
-
SFO
24h 05m2 stops
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m1 stop
$510Avianca
Thu, Mar 26 - Sat, Apr 4
Avianca Logo
3:50 pm - 11:40 pm
PTY
-
SFO
9h 50m1 stop
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m1 stop
$513Avianca
Sun, Feb 22 - Sat, Feb 28
Avianca Logo
5:50 pm - 12:00 pm
PTY
-
SFO
21h 10m2 stops
Avianca Logo
1:35 am - 6:55 pm
SFO
-
PTY
14h 20m1 stop
$514Avianca
Tue, Apr 7 - Tue, Apr 14
Avianca Logo
3:50 pm - 11:55 pm
PTY
-
SFO
10h 05m1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m1 stop
$520Avianca
Tue, May 5 - Sat, May 9
Avianca Logo
3:20 am - 10:35 pm
PTY
-
SFO
21h 15m2 stops
Avianca Logo
11:55 pm - 4:30 pm
SFO
-
PTY
14h 35m2 stops
$521Avianca
Fri, Mar 6 - Sun, Mar 8
Avianca Logo
7:50 pm - 12:00 pm
PTY
-
SFO
19h 10m1 stop
Avianca Logo
12:10 am - 10:30 am
SFO
-
PTY
8h 20m1 stop
$530Avianca
Booking Insights

KAYAK's insights & trends for flights to San Francisco

Get data-powered insights and trends for flights to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Francisco is August, where tickets cost $506 on average for one-way flights. On the other hand, the most expensive months are February and March, where the average cost of tickets from Panama is $711 and $696 respectively. For return trips, the best month to travel is August with an average price of $506.

What is a good deal for flights to San Francisco?

If you’re looking for cheap airfare to San Francisco, 25% of our users found tickets to San Francisco for the following prices or less: From Panama City $363 one-way - $573 round-trip.

How far in advance should I book a flight to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 64 days before departure.

Good to know

Low seasonJanuary
Cheapest flight$277
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Panama City to San Francisco

FAQs - booking San Francisco flights

  • How far is San Francisco Airport from central San Francisco?

    You’ll need to travel 12 miles to reach the San Francisco city center from San Francisco Airport.

  • What is the name of San Francisco’s airport?

    San Francisco is served by San Francisco Airport, also commonly referred to as San Francisco or San Francisco Intl. The airport code is SFO.

  • How much is a flight to San Francisco?

    On average, a flight to San Francisco costs $935. The cheapest price found on KAYAK in the last 2 weeks cost $299 and departed from Panama City Tocumen Intl Airport.

  • What is the cheapest day to fly to San Francisco?

    Based on KAYAK data, the cheapest day to fly to San Francisco is Monday where tickets can be as cheap as $694. On the other hand, the most expensive day to fly is Tuesday, where prices are $815 on average.

  • How does KAYAK find such low prices on flights to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to San Francisco?

    The cheapest time of day to fly to San Francisco is generally in the morning, when flights cost $574 on average. The most expensive time of day to fly to San Francisco is generally in the evening, which is peak travel time and where the average cost of a ticket is $761.

Top tips for finding cheap flights to San Francisco

  • Looking for cheap airfare to San Francisco? 25% of our users found round-trip tickets to San Francisco for the following prices or less: From Panama City $468
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Francisco flight deals.

Reviews of the top 3 airlines serving from Panama to San Francisco

 
See real verified KAYAK customer reviews for airlines flying to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Francisco. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1563 reviews
6.8Entertainment
8.1Crew
7.4Comfort
6.8Food
7.8Boarding
Airline reviews

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

2.0 MediocreAnonymous, Dec 2025
PTY - POA
Read more Copa Airlines reviews

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Some of the Air hostesses are not that friendly. Need improvement

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

On the way my flight entertainment wouldn’t work the screen went black and no matter how many times I tried to turn it on it wouldn’t. Food was surprisingly good but the tray tables were tiny so you couldn’t get anything else on the table. The seats hardly go back and are not overly comfortable. Wouldn’t fly United again.

Flight was late - I was downgraded from first class to coach

Movie selection is good. Crew did not understand mileage program and were no help. Sick later. Food?

United needs to step up their game. Delayed flight leaving Seattle, San Francisco. Older aircraft, not very comfortable.

The flight attendants were very rude, beyond comprehension. I took a business class from London to SFO for the first time on United. When I asked for a second piece of bread during dinner, the serving attendant threw a 3rd bread on my plate and said, “here. You can have this one too”! I couldn’t believe the rudeness of the attendant. Most all attendants were very rude, unhelpful, sing the food was absolutely disgusting. Never fly United internationally in business class. My flight back to SFO was a nightmare!!

7 hours delayed due to operational issues on United’s end. Basically laziness.

Flight from Rome to SFO was excellent compared To our flight to Europe from SFO. The food was much tastier. You can see how UNITED is skimping, though. Instead of getting something mid flight you had to ask for it. It was not automatically served. There was a cookie at the end of the arrival meal, for example that tasted like it just came out of a box. They used to serve a little container of nuts, now … a tiny container of nuts, mixed with pretzels. This was business class that you really have to pay for! But this is minor complaints compared to the overall. My major complaint is the position of the even numbered seats by the windows. You have to turn around to see your window & the positioning as some other controls are harder to get at. This is compared to the odd number seat that are perfectly aligned.

The food quality sucks. One must starve if they do not eat flesh Or wheat based products Some variety would be expected. The trivial amount of snacks and or food is inhumane

The internet service I paid for didn’t work at all and the flight crew was not very friendly.

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

We waited for one hour to deboard the plane after landing. That could be better

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Boarding, crew were excellent, food was ok and entertainment need to improve

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
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Everything you need to know for your flight to San Francisco

Information on the airport you'll fly into in San Francisco