$297 Find Cheap Flights from Panama to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Francisco

Tue, Sep 1 - Tue, Sep 8
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$606Avianca
Tue, May 5 - Tue, May 12
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$611Avianca
Fri, May 8 - Fri, May 15
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
$614Avianca
Fri, Sep 11 - Fri, Sep 25
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$619Avianca
Tue, May 19 - Thu, May 28
Avianca Logo
3:50 pm - 11:55 pm
PTY
-
SFO
10h 05m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$623Avianca
Tue, May 5 - Wed, May 20
Multiple Airlines Logo
5:55 pm - 11:04 pm
PTY
-
SFO
31h 09m
2 stops
Multiple Airlines Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
$625Multiple Airlines
Sun, Apr 26 - Sun, May 3
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
$626Avianca
Tue, May 5 - Wed, May 20
Multiple Airlines Logo
3:10 pm - 11:04 pm
PTY
-
SFO
33h 54m
2 stops
Multiple Airlines Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$627Multiple Airlines
Tue, May 5 - Wed, May 20
Avianca Logo
10:10 am - 10:35 pm
PTY
-
SFO
14h 25m
2 stops
Avianca Logo
11:55 pm - 5:00 pm
SFO
-
PTY
15h 05m
2 stops
$629Avianca
Sat, May 23 - Sat, May 30
Avianca Logo
3:50 pm - 11:55 pm
PTY
-
SFO
10h 05m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$630Avianca
Booking Insights

KAYAK's insights & trends for flights to San Francisco

Get data-powered insights and trends for flights to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest flight to San Francisco?

These are the best round-trip prices found by users searching on KAYAK in the last 72 hours.

In the last 3 days, the cheapest flight deal to San Francisco was found on the route from Panama City, at $606 return. The most popular connection is from Los Angeles to San Francisco and KAYAK users have found round-trip deals for as low as $92 in the last 3 days.

What is the cheapest day to fly to San Francisco?

The average price of all round-trip flights to San Francisco clicked on KAYAK for each day over the last 12 months.

Based on KAYAK data, the cheapest day to fly to San Francisco is Saturday where round-trip tickets can be as cheap as $693. On the other hand, the most expensive day to fly is Sunday, where round-trip prices are $970 on average.

What is the cheapest month to fly to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Francisco is April, where tickets cost $562 on average for return flights. On the other hand, the most expensive months are February and March, where the average cost of tickets from Panama is $793 and $780 respectively. For one-way flights, the best month to travel is April with an average price of $562.

What is the cheapest time of day to fly to San Francisco?

The average price for all round-trip flights to San Francisco depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to San Francisco is generally in the morning, when round-trip flights cost $562 on average. The most expensive time of day to fly to San Francisco is generally in the evening, which is peak travel time and where the average cost of a ticket is $774.

How far in advance should I book a flight to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price, you should book around 5 weeks before departure, which saves you about 31% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Good to know

Low seasonMarch
Cheapest flight$297
Best time to beat the crowds but there is an average 20% increase in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Panama City to San Francisco

FAQs - booking San Francisco flights

  • What is the cheapest flight to San Francisco?

    In the last 3 days, the cheapest flight deal to San Francisco was found on the route from Panama City, at $606 return. The most popular connection is from Los Angeles to San Francisco and KAYAK users have found round-trip deals for as low as $92 in the last 3 days.

  • How far is San Francisco Airport from central San Francisco?

    You’ll need to travel 11 miles to reach the San Francisco city center from San Francisco Airport.

  • What is the name of San Francisco’s airport?

    San Francisco is served by San Francisco Airport, also commonly referred to as San Francisco or San Francisco Intl. The airport code is SFO.

  • How much is a flight to San Francisco?

    On average, a flight to San Francisco costs $573. The cheapest price found on KAYAK in the last 2 weeks cost $374 and departed from Panama City Tocumen Intl Airport.

  • How does KAYAK find such low prices on flights to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to San Francisco

  • Looking for cheap airfare to San Francisco? 25% of our users found round-trip tickets to San Francisco for the following prices or less: From Panama City $1,145
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Francisco flight deals.

Reviews of the top 3 airlines serving from Panama to San Francisco

 
See real verified KAYAK customer reviews for airlines flying to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Francisco. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1575 reviews
8.1Crew
6.8Entertainment
7.7Boarding
7.4Comfort
6.8Food
Airline reviews

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

10.0 ExcellentAnonymous, Apr 2026
DAV - PTY
Read more Copa Airlines reviews

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Flight left on time, arrived early, pleasant staff provided water, coffee, etc. access to bathrooms was reasonable and were well maintained. blankets were available, lots of entertainment options. LUGGAGE SERVICE WAS GREAT. I got my one checked bag quickly and was able to make a bus connection for a 2 hour bus ride saving me from waiting another 1.5 hours.

Wonderful in-seat entertainment with seatback screens and huge selection of quality movies. The ability to bluetooth connect headphones was amazing.

we did a return flight from Paris CDG to SFO. This trip was much better than the departing flight SFO to CDG. The food was better quality, the crew was nicer, and the interior of the plane seemed cleaner.

Horrible service no Wi-Fi connection on both leg of the flight and they are refusing to fix bad service

We got to get extended leg room in Econ plus that was great. It was nice having our own dietary needs met with our meals, and the connecting flights had it as well. Only negative were the seats my bottom was/is really sore after a ten plus hour flight. Those seats are horrible, understandable for as many people use them. So we are going to purchase a gel seat pad.

Flight to Japan was was better across the board than the return to USA. Entertainment: Movie selection was old and not to my liking. Way too many woke choices. Not enough selections for sports or drama. Service: some of the crew were great. Not all. I paid for business class. a premium. Some of the crew thought they 'had' t do there job instead of wanting to serve and be polite. Food: Way to Japan was good. Way back to USA bad. Boarding: Wat out did not offer Business only; had to go thru general. If you pay for business, you should get business perks. Suggest you look for other than United for travel to Asia

I will never fly ANA again. They lost one of my large pieces of checked luggage, the heaviest one with the most valuable items in it, and they said they will not send me an email unless they can't find it, even though the paper they gave me to track the status of my lost luggage requires a code from an email they are supposed to send me so I can do baggage tracing. They claim to be an international airline, but they also insist on calling a Japanese telephone number to confirm where to send the lost baggage if they find it. It is impossible to find an actual contact email address for customer support on their website, and their AI chatbot is unhelpful, directing you to a webpage that says it is for contact information but does not have any actual email addresses or phone numbers listed on it. My seat in economy did not recline at all, even though I was not sitting in an exit row nor the very back row. I had to sit in the fully upright position for over ten hours of international travel. Awful experience overall.

The head flight attendant made the trip excellent. He was very accommodating.

The economy seats on the 777 was not as cramped as I had feared, but the food was terrible.

Terrible experience! delay 2 time and say i dont have ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

We waited for one hour to deboard the plane after landing. That could be better

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Boarding, crew were excellent, food was ok and entertainment need to improve

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Calistoga
Rohnert Park
Marina
Emeryville
Pacifica
Capitola
Millbrae
Campbell
Newark
Mill Valley
Novato
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Union City
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West Sacramento
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Los Altos
Jenner

Everything you need to know for your flight to San Francisco

Information on the airport you'll fly into in San Francisco