$280 Find Cheap Flights from Panama to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Francisco

Wed, Apr 8 - Wed, Apr 15
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
$495Avianca
Thu, Apr 9 - Tue, May 12
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$497Avianca
Tue, Apr 7 - Tue, Apr 14
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
11:55 pm - 5:00 pm
SFO
-
PTY
15h 05m
2 stops
$501Avianca
Wed, Apr 8 - Wed, Apr 15
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$505Avianca
Fri, Apr 10 - Sat, Apr 25
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
$510Avianca
Fri, Apr 10 - Thu, Apr 16
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
2:30 am - 1:55 am
SFO
-
PTY
21h 25m
1 stop
$511Avianca
Fri, Apr 3 - Sat, Apr 18
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$518Avianca
Tue, Apr 7 - Tue, Apr 14
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
$520Avianca
Fri, Mar 20 - Mon, Mar 30
Avianca Logo
7:50 pm - 1:00 pm
PTY
-
SFO
19h 10m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$521Avianca
Tue, Apr 7 - Tue, Apr 14
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$522Avianca
Booking Insights

KAYAK's insights & trends for flights to San Francisco

Get data-powered insights and trends for flights to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Francisco is August, where tickets cost $506 on average for one-way flights. On the other hand, the most expensive months are February and December, where the average cost of tickets from Panama is $793 and $693 respectively. For return trips, the best month to travel is August with an average price of $506.

What is a good deal for flights to San Francisco?

If you’re looking for cheap airfare to San Francisco, 25% of our users found tickets to San Francisco for the following prices or less: From Panama City $344 one-way - $793 round-trip.

How far in advance should I book a flight to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price, you should book around 1 week before departure. For the absolute cheapest price, our data suggests you should book 64 days before departure.

Good to know

Low seasonJanuary
Cheapest flight$280
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Panama City to San Francisco

FAQs - booking San Francisco flights

  • How far is San Francisco Airport from central San Francisco?

    You’ll need to travel 12 miles to reach the San Francisco city center from San Francisco Airport.

  • What is the name of San Francisco’s airport?

    San Francisco is served by San Francisco Airport, also commonly referred to as San Francisco or San Francisco Intl. The airport code is SFO.

  • How much is a flight to San Francisco?

    On average, a flight to San Francisco costs $670. The cheapest price found on KAYAK in the last 2 weeks cost $344 and departed from Panama City Tocumen Intl Airport.

  • What is the cheapest day to fly to San Francisco?

    Based on KAYAK data, the cheapest day to fly to San Francisco is Monday where tickets can be as cheap as $694. On the other hand, the most expensive day to fly is Thursday, where prices are $805 on average.

  • How does KAYAK find such low prices on flights to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to San Francisco?

    The cheapest time of day to fly to San Francisco is generally in the morning, when flights cost $562 on average. The most expensive time of day to fly to San Francisco is generally in the evening, which is peak travel time and where the average cost of a ticket is $760.

Top tips for finding cheap flights to San Francisco

  • Looking for cheap airfare to San Francisco? 25% of our users found round-trip tickets to San Francisco for the following prices or less: From Panama City $568
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Francisco flight deals.

Reviews of the top 3 airlines serving from Panama to San Francisco

 
See real verified KAYAK customer reviews for airlines flying to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Francisco. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1556 reviews
8.1Crew
7.8Boarding
6.8Entertainment
7.4Comfort
6.8Food
Airline reviews

Flight got delayed; had to go through security three times.

2.0 MediocreAnonymous, Feb 2026
PTY - JFK
Read more Copa Airlines reviews

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Some of the Air hostesses are not that friendly. Need improvement

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Flight attendants had a little attitude. Food tastes no good.

Overall we had a good experience during our flight from San Francisco to Houston.

Good flight. However, when booked flight with United, assumed the layover included by United in San Francisco of 1 hr and 40 minutes was sufficient . Not so and would recommend at least 2 hours or more. Needed to go through US immigration (very long lineups), then pick up bags, take all the way to another terminal, running because we did not have sufficient time. We made the flight because they held the door for us but luggage didn’t follow.

the whole trip was smooth, and as comfortable as flying is these days. flight crew was friendly and very courteous and helpful.

Very poor. The flight was delayed from Toronto because some forget to do there job . I got to my connecting gate in San Francisco 10 minutes before the departure.but this didn’t let me board even though the flight was still there for an other 30 minutes. The the gentleman at the unite airline desk told me that they usually wait for passengers but air Canada called and told them not to we I been rerouted to Manila instead of Hong Kong . In San Francisco they mad me check in my carryon bag . I was told the it will directly go yo ho chi minn cuyt but I was told that by the Vietnams airline desk that’s not there I’m 10 hours behind my scheduled flight and looks like I I’m going without baggage. I don’t have a chance of catching ..

First class ticket gets you a choice of chips or nuts. . Just like economy Southwest. Also no screen in the seats. This is first class???!

Flight arrived 30 min early and bag was waiting at the baggage pickup. United Club HNL was one of the nicest in the system

Mean flight attendant. I wanted to reuse my plastic cup, but he (Matthew) said he can't for safety. I then said "I don't want water then" and he poured me a glass. I hope Matthew gets herpes and spends the rest of his life poor, lonely, and homeless.

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Both flights delayed. 2nd flight over 3 hours late mechanical issues

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

We waited for one hour to deboard the plane after landing. That could be better

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Boarding, crew were excellent, food was ok and entertainment need to improve

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Calistoga
Rohnert Park
Marina
Emeryville
Capitola
Pacifica
Millbrae
Campbell
Mill Valley
Newark
Novato
Windsor
Union City
Belmont
Richmond
West Sacramento
American Canyon
Los Altos
Corte Madera
Jenner

Everything you need to know for your flight to San Francisco

Information on the airport you'll fly into in San Francisco