$287 Find Cheap Flights from Panama to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results for flights to San Francisco, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama to San Francisco

Sat, Sep 27 - Mon, Oct 6
Avianca Logo
3:40 pm - 10:45 pmPTY-SFO
9h 05m1 stop
Avianca Logo
2:20 pm - 8:55 amSFO-PTY
16h 35m2 stops
$493Avianca
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Mon, Sep 15 - Wed, Sep 17
Avianca Logo
3:40 pm - 10:45 pmPTY-SFO
9h 05m1 stop
Avianca Logo
12:05 am - 2:45 pmSFO-PTY
12h 40m1 stop
$495Avianca
Find Deal
Mon, Sep 29 - Mon, Oct 6
Avianca Logo
11:00 am - 10:45 pmPTY-SFO
13h 45m2 stops
Avianca Logo
2:20 pm - 10:25 amSFO-PTY
18h 05m1 stop
$499Avianca
Find Deal
Mon, Sep 15 - Thu, Sep 18
Avianca Logo
10:05 pm - 12:35 pmPTY-SFO
16h 30m2 stops
Avianca Logo
2:20 pm - 10:10 amSFO-PTY
17h 50m2 stops
$500Avianca
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Sat, Oct 11 - Sat, Oct 18
United Airlines Logo
3:35 pm - 9:10 pmPTY-SFO
7h 35mnonstop
United Airlines Logo
11:59 pm - 6:37 pmSFO-PTY
16h 38m1 stop
$507United Airlines
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Sat, Sep 27 - Sat, Oct 4
United Airlines Logo
3:35 pm - 9:10 pmPTY-SFO
7h 35mnonstop
United Airlines Logo
10:55 am - 8:10 pmSFO-PTY
7h 15mnonstop
$534United Airlines
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Wed, Nov 26 - Tue, Dec 30
American Airlines Logo
2:43 pm - 10:00 amPTY-SFO
22h 17m2 stops
American Airlines Logo
11:49 pm - 3:20 pmSFO-PTY
12h 31m2 stops
$605American Airlines
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Fri, Oct 17 - Tue, Oct 21
Delta Logo
2:21 pm - 11:56 pmPTY-SFO
11h 35m1 stop
Delta Logo
3:00 pm - 12:56 pmSFO-PTY
19h 56m1 stop
$608Delta
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Sat, Oct 11 - Fri, Oct 17
Copa Airlines Logo
5:50 pm - 11:39 pmPTY-SFO
7h 49mnonstop
Copa Airlines Logo
1:31 am - 10:41 amSFO-PTY
7h 10mnonstop
$649Copa Airlines
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Sat, Nov 15 - Mon, Dec 1
American Airlines Logo
2:43 pm - 10:58 pmPTY-SFO
11h 15m1 stop
American Airlines Logo
5:00 pm - 1:36 pmSFO-PTY
17h 36m2 stops
$654American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for flights to San Francisco

Get data-powered insights and trends for flights to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to San Francisco is August, where tickets cost $537 on average for return flights. On the other hand, the most expensive months are March and October, where the average cost of tickets from Panama is $685 and $677 respectively. For one-way flights, the best month to travel is August with an average price of $537.

What is a good deal for flights to San Francisco?

If you’re looking for cheap airfare to San Francisco, 25% of our users found tickets to San Francisco for the following prices or less: From Panama City $601 round-trip.

How far in advance should I book a flight to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price, you should book around 7 weeks before departure, which saves you about 33% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 10 weeks before departure.

Good to know

Low seasonAugust
Cheapest flight$287
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from Panama City to San Francisco

FAQs - booking San Francisco flights

  • How far is San Francisco Airport from central San Francisco?

    You’ll need to travel 12 miles to reach the San Francisco city center from San Francisco Airport.

  • What is the name of San Francisco’s airport?

    San Francisco is served by San Francisco Airport, also commonly referred to as San Francisco or San Francisco Intl. The airport code is SFO.

  • How much is a flight to San Francisco?

    On average, a flight to San Francisco costs $633. The cheapest price found on KAYAK in the last 2 weeks cost $319 and departed from Panama City Tocumen Intl Airport.

  • What is the cheapest day to fly to San Francisco?

    Based on KAYAK data, the cheapest day to fly to San Francisco is Monday where round-trip tickets can be as cheap as $634. On the other hand, the most expensive day to fly is Friday, where round-trip prices are $816 on average.

  • How does KAYAK find such low prices on flights to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to San Francisco?

    The cheapest time of day to fly to San Francisco is generally at night, when round-trip flights cost $433 on average. The most expensive time of day to fly to San Francisco is generally in the evening, which is peak travel time and where the average cost of a ticket is $731.

  • How many direct flights to San Francisco are there each week?

    Each week there are around 3,097 direct flights from within Panama to San Francisco. The most common day for departures is Sunday, with 15% of flights taking off on this day.

Top tips for finding cheap flights to San Francisco

  • Looking for cheap airfare to San Francisco? 25% of our users found round-trip tickets to San Francisco for the following prices or less: From Panama City $499
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest San Francisco flight deals.

Reviews of the top 3 airlines serving from Panama to San Francisco

 
See real verified KAYAK customer reviews for airlines flying to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from Panama to San Francisco. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1509 reviews
7.8Boarding
6.8Entertainment
8.1Crew
7.4Comfort
6.8Food
Airline reviews

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

8.0 ExcellentAnonymous, Aug 2025PTY - ORD
Read more Copa Airlines reviews

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Great experience with a crew always thinking in the passenger

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

Seats not reclining, no vegetarian food option, no snacks. 7.5 hr flight should have been more comfortable. Luggage limits are unusually small. Will never fly Copa again and will tell friends and family to avoid this airline.

We paid extra with copa for seats near one another The plane was changed and we lost our seats We were all Separated. We have not received a refund for our seats despite emailing and calling.

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

It was ok. However, the food was quite poor since I don't eat pasta.

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

1. when we went to check in, our 2 first class seats had been CANCELED and the flight was sold out. This was done without our prior knowledge. It was all we could do to restore one first class seat for my wife and I flew economy. 2, Our flight home was scheduled to leave at 10:30 pm. Due to tsunami warnings, the roads were closed and our flight status was uncertain as to whether it would leave as scheduled. It was announced that it would now leave at 11:20 pm and the roads were now open since the tsunami had come and gone. We made a mad dash to the airport and checked in. Delays were announced at 12:30 pm, 1:30 am, 2:30 am and at 3:30 am it was canceled. Since this was a flight due to natural (tsunami) causes, there was no compensation. We were told to return at 1:00 pm the next day and our baggage would be kept on the plane since the same plane was going to leave at 1:00 pm. We had to return to our hotel for the rest of the night. The same plane did not leave at 1:00 pm and our baggage was gone! All in all, it was a miserable performance by UA. Information was hard to obtain and no one knew what was going on and what was going to happen. Hundreds of passengers slept on the floor, chairs, etc. No food and no water was made available to the passengers. It was a situation where UA could care less what was going on. As a one million mile flyer, I had not experienced anything like this before and it was hugely disappointing!

I found the staff to not be very attentive at all. When paying for Business Class you expect a certain type of service and that was not found. They were almost rude even

Our experience on United Airlines was extremely poor. The plane was extremely cold throughout our entire flight- which multiple people complained about- and we had to wait 2 hours to get a blanket which was too thin and barely helped warm us up. As well as this, none of the entertainment features were working so we had to sit through a roughly 10 hour flight with nothing to keep our attention, including the actual flight path screen. It was an extremely disappointing experience and I would hope that this gets fixed if we ever choose United Airlines again.

I really enjoyed flying with United airlines amazing experience , good customer service and great food

1.It will be better if sandwich is warm. 2.The food is too salty. 3.Breakfast needs some vegetables or fruits.

Boarded plane and then delayed 1.5 hours while on the plane

It was all good flight was on time, service was good I enjoyed a few movies and everything was smooth

My flight was delayed a very short period of time but they did not hold my connecting flight to San Diego, also through United. So they closed the doors before we got off our plane. They would only have to help the door open for another five to ten minutes. So I missed a court deadline for a manditory mediation settlement conference for my client. I had to get an associate to be there in person and be on the phone with him relaying what he needs to do the entire time. The court was very upset with me and so was my client. United cannot be trusted.

Really good 😊 the woman at the gate entrance was a little rude checking in our carry-on but i dont think she worked for the airline, she worked for the airport at sacramento, other than that amazing.

Boarding was mayhem. Late boarding by 15 minutes because of lack of staff (missing 1 flight attendant. We had to wait for an arrival of another plane before we could board). Flight was a little rough, but cannot blame on airlines.

Very uncomfortable planes , poor service on the plane , take your own water so you don’t dehydrate , in a 6 hs flight they sold one time food and beverage . 1 plane was delayed 6 hs , I lost a connecting flight . Then in the way back they announce a delay of 2 hs so I had to take a different flight to arrive on time for my connecting flight . Avoid this airline .

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

Avianca is not what it used to be. So disappointing

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

why did we have to go through security mid flight

Seats are very tight even in Plus, no complimentary snacks or beverage

The chicken that was served in business class was cold!

A few years ago long flights 6 hours or so used to have video screens and they offered ear phones. The food cart used to come and drinks. Now absolutely nothing. Avianca is as bad as Spirit Airlines. Avianca will now be my last choice when booking my next flight.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
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Millbrae
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Everything you need to know for your flight to San Francisco

Information on the airport you'll fly into in San Francisco

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