$456 Find Cheap Flights from San Francisco to Patagonia

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Patagonia departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Patagonia

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Patagonia, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Patagonia, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Francisco to Patagonia

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
El Calafate
El Calafate3 stops$1,581
Ushuaia
Ushuaia3 stops$1,237
Puerto Natales
Puerto Natales3 stops$1,269
Punta Arenas
Punta Arenas2 stops$897
Puerto Montt
Puerto Montt2 stops$963
Temuco
Temuco2 stops$863
Valdivia
Valdivia2 stops$861
Trelew
Trelew3 stops$1,552
El Calafate
El Calafate3 stops$1,581
Ushuaia
Ushuaia3 stops$1,237
Puerto Natales
Puerto Natales3 stops$1,269
Punta Arenas
Punta Arenas2 stops$897
Puerto Montt
Puerto Montt2 stops$963
Temuco
Temuco2 stops$863
Valdivia
Valdivia2 stops$861
Trelew
Trelew3 stops$1,552

Book Cheap San Francisco to Patagonia Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Patagonia that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Patagonia

Sat, Apr 18 - Wed, Apr 22
LATAM Airlines Logo
6:00 am - 2:26 pm
SFO
-
ZAL
29h 26m
2 stops
LATAM Airlines Logo
1:53 pm - 3:21 pm
ZAL
-
SFO
28h 28m
2 stops
$861LATAM Airlines
Sat, Apr 18 - Wed, Apr 22
LATAM Airlines Logo
9:25 am - 8:55 am
SFO
-
ZCO
20h 30m
2 stops
LATAM Airlines Logo
4:11 pm - 11:59 am
ZCO
-
SFO
22h 48m
2 stops
$863LATAM Airlines
Sat, Apr 18 - Wed, Apr 22
LATAM Airlines Logo
9:25 am - 1:29 pm
SFO
-
PUQ
24h 04m
2 stops
LATAM Airlines Logo
2:10 pm - 11:59 am
PUQ
-
SFO
25h 49m
3 stops
$897LATAM Airlines
Sat, Apr 18 - Wed, Apr 22
LATAM Airlines Logo
9:20 am - 2:26 pm
SFO
-
ZAL
26h 06m
2 stops
LATAM Airlines Logo
1:53 pm - 6:59 pm
ZAL
-
SFO
32h 06m
2 stops
$934LATAM Airlines
Sat, Apr 18 - Wed, Apr 22
LATAM Airlines Logo
5:50 pm - 3:16 am
SFO
-
PUQ
29h 26m
3 stops
LATAM Airlines Logo
2:10 pm - 11:59 am
PUQ
-
SFO
25h 49m
3 stops
$940LATAM Airlines
Sat, Apr 18 - Wed, Apr 22
LATAM Airlines Logo
8:00 am - 12:59 pm
SFO
-
ZCO
25h 59m
2 stops
LATAM Airlines Logo
3:11 pm - 11:59 am
ZCO
-
SFO
23h 48m
2 stops
$958LATAM Airlines
Sun, Apr 19 - Thu, Apr 23
LATAM Airlines Logo
6:00 am - 2:35 pm
SFO
-
PMC
29h 35m
2 stops
LATAM Airlines Logo
5:18 pm - 8:24 pm
PMC
-
SFO
30h 06m
2 stops
$963LATAM Airlines
Sat, Apr 18 - Wed, Apr 22
LATAM Airlines Logo
2:30 pm - 3:16 am
SFO
-
PUQ
32h 46m
3 stops
LATAM Airlines Logo
9:50 am - 11:59 am
PUQ
-
SFO
30h 09m
2 stops
$1,003LATAM Airlines
Tue, Apr 14 - Thu, Apr 16
Multiple Airlines Logo
8:29 am - 1:08 pm
SFO
-
ZAL
25h 39m
2 stops
Multiple Airlines Logo
6:25 pm - 11:20 pm
ZAL
-
SFO
31h 55m
3 stops
$1,011Multiple Airlines
Tue, Mar 10 - Sun, Mar 29
Aeromexico Logo
11:35 pm - 11:45 am
SFO
-
USH
32h 10m
2 stops
Aeromexico Logo
4:20 pm - 1:00 pm
USH
-
SFO
24h 40m
2 stops
$3,961Aeromexico
Booking Insights

KAYAK's insights & trends for San Francisco to Patagonia flights

Get data-powered insights and trends into flights from San Francisco to Patagonia to help you find the cheapest flights, the best time to fly and much more.

Can I save money by flying with a layover from San Francisco to Patagonia?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $571, prices are generally cheapest when you fly direct.

Good to know

Cheapest flight$456
Flight from San Francisco to San Carlos de Bariloche

FAQs - booking Patagonia flights

  • How does KAYAK find such low prices on flights from San Francisco to Patagonia?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Patagonia.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Patagonia?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Francisco to Patagonia is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Patagonia?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Francisco to Patagonia with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Patagonia?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Francisco to Patagonia up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from San Francisco to Patagonia

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Patagonia. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Patagonia? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1920 reviews
7.3Comfort
7.0Entertainment
6.7Food
8.0Crew
7.5Boarding
Airline reviews

Apart of Sky miles delta. And they go everywhere in Brazil

10.0 ExcellentAnonymous, Feb 2026
MCO - GRU
Read more LATAM Airlines reviews

Apart of Sky miles delta. And they go everywhere in Brazil

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

There was a mechanical issue with the plane that they had to work on before we could take off. That's fine, by all means, PLEASE make sure the mechanics are functioning properly. What was a problem was the fact that we sat on the tarmac for 4.5 hours without moving, without letting us off the plane, and without climate control and air running through the plane. There was no explanation as to what was going on; they just kept promising that it would be "15 minutes, then we are on our way." At one point, they even switched the entire crew out and told everyone we just needed to wait for new employees to show up. Then, as the 4 hours were not moving, an hour before the full refund, they made a big show about "the flight starting and the doors are locked, so you have to sit down." We didn't move for another 40 minutes; they were just trying to skirt around legalities that entitled us to restitution. When the flight finally was underway, the plane was gigantic but cramped in design, my entertainment screen kept freezing and glitching, and subtitles didn't work, and the crew was passive-aggressive. Terrible flight.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Wish the seats were a little more comfortable.. it was a 6 hrs nonstop trip. But the crew was courteous and w a smile

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Everything you need to know for your flight to Patagonia

Information on your arrival and departure airports