Find cheap flights from San Francisco to South America

Find cheap flights from San Francisco to South America

Round-trip
Economy
San Francisco (SFO)
South America
Thu 3/4
Thu 3/11
Any month
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Good to know

Low season

August Best time to beat the crowds with an average 5% drop in price.

High season

December Most popular time to fly with an average 22% increase in price.

Average price round-trip

$966 (avg. price over the last 2 weeks)

Good deal round-trip

$570 or less

Good deal one-way

$259 or less

Top tips for finding cheap flights to South America

  • Book at least 3 weeks before departure in order to get a below-average price.
  • High season is considered to be January, November and December. The cheapest month to fly to South America is August.
  • Morning departure is around 14% cheaper than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

FAQs - booking South America flights

How long is the flight to South America from San Francisco?

What is the cheapest flight to South America from San Francisco?

How does KAYAK find such low prices on flights to South America?

How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to South America?

What is the Hacker Fare option on flights to South America?

What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to South America?

COVID-19 information

Safety measures for airlines flying from San Francisco to South America

Airlines flying from San Francisco to South America have enacted additional safety measures and adjusted policies to better accommodate travelers. Policies vary by airline.

Heightened sanitation

Daily cleaning, installation of cabin HEPA filters on flights from San Francisco to South America

Mandatory masks

Masks required on board, masks provided on flights from San Francisco to South America

Social distancing seating

Middle seats unavailable to book on flights from San Francisco to South America

Pre-flight testing

Testing for antibodies, testing for symptoms for flights from San Francisco to South America

Book cheap flights from San Francisco to South America

Recent round-trip flight deals

4/15
Thu
3 stops
Multiple Airlines
33h 08m
SFO - LIM
4/22
Thu
2 stops
Multiple Airlines
27h 02m
LIM - SFO
4/15
Thu
3 stops
Multiple Airlines
33h 08m
SFO - LIM
4/28
Wed
2 stops
Multiple Airlines
27h 02m
LIM - SFO
4/15
Thu
3 stops
Multiple Airlines
33h 08m
SFO - LIM
4/22
Thu
3 stops
Multiple Airlines
39h 09m
LIM - SFO
4/15
Thu
3 stops
Multiple Airlines
33h 08m
SFO - LIM
4/21
Wed
3 stops
Multiple Airlines
32h 33m
LIM - SFO
4/30
Fri
3 stops
Multiple Airlines
25h 43m
SFO - LIM
5/16
Sun
2 stops
Multiple Airlines
27h 02m
LIM - SFO
4/5
Mon
1 stop
JetBlue
14h 28m
SFO - BOG
4/15
Thu
1 stop
JetBlue
16h 40m
BOG - SFO
7/23
Fri
1 stop
Copa Airlines
13h 37m
SFO - BOG
7/31
Sat
1 stop
Copa Airlines
17h 28m
BOG - SFO
4/20
Tue
1 stop
Aeromexico
31h 50m
SFO - UIO
5/12
Wed
1 stop
Aeromexico
14h 45m
UIO - SFO
6/25
Fri
1 stop
Copa Airlines
14h 05m
SFO - UIO
7/3
Sat
1 stop
Copa Airlines
12h 36m
UIO - SFO
8/15
Sun
1 stop
Copa Airlines
17h 26m
SFO - UIO
9/27
Mon
1 stop
Copa Airlines
10h 55m
UIO - SFO
8/16
Mon
1 stop
Avianca
15h 10m
SFO - UIO
9/26
Sun
2 stops
Avianca
23h 20m
UIO - SFO
8/16
Mon
1 stop
Avianca
15h 10m
SFO - UIO
9/27
Mon
2 stops
Avianca
26h 30m
UIO - SFO
4/11
Sun
1 stop
Aeromexico
31h 50m
SFO - UIO
4/17
Sat
2 stops
Aeromexico
47h 18m
UIO - SFO
4/20
Tue
1 stop
United Airlines
13h 40m
SFO - UIO
5/11
Tue
1 stop
United Airlines
14h 15m
UIO - SFO
4/6
Tue
1 stop
Delta
18h 45m
SFO - UIO
4/24
Sat
1 stop
Delta
15h 07m
UIO - SFO
4/8
Thu
2 stops
American Airlines
16h 39m
SFO - UIO
4/15
Thu
2 stops
American Airlines
17h 51m
UIO - SFO
8/5
Thu
1 stop
American Airlines
13h 28m
SFO - UIO
11/8
Mon
2 stops
American Airlines
23h 39m
UIO - SFO
7/5
Mon
2 stops
LATAM Airlines
28h 15m
SFO - GRU
7/28
Wed
2 stops
LATAM Airlines
33h 30m
GRU - SFO
7/15
Thu
1 stop
Aerolineas Argentinas
16h 40m
SFO - EZE
7/26
Mon
1 stop
Aerolineas Argentinas
19h 59m
EZE - SFO
6/6
Sun
2 stops
Air Canada
28h 15m
SFO - SDU
7/30
Fri
2 stops
Air Canada
54h 00m
SDU - SFO
Show more results

Recent one-way flight deals

4/5
Mon
2 stops
Multiple Airlines
33h 53m
SFO - BOG
5/3
Mon
3 stops
Multiple Airlines
25h 43m
SFO - LIM
3/27
Sat
2 stops
Multiple Airlines
34h 30m
SFO - BOG
4/3
Sat
3 stops
Multiple Airlines
46h 34m
SFO - BOG
4/7
Wed
3 stops
Multiple Airlines
36h 38m
SFO - MDE
4/27
Tue
3 stops
Multiple Airlines
30h 38m
SFO - LIM
5/16
Sun
2 stops
Multiple Airlines
22h 37m
SFO - BOG
4/4
Sun
2 stops
Multiple Airlines
22h 30m
SFO - MDE
7/4
Sun
1 stop
Copa Airlines
9h 59m
SFO - BOG
6/26
Sat
1 stop
Copa Airlines
14h 05m
SFO - UIO
4/10
Sat
1 stop
JetBlue
12h 18m
SFO - MDE
5/25
Tue
1 stop
JetBlue
13h 41m
SFO - CTG
5/30
Sun
1 stop
JetBlue
12h 19m
SFO - UIO
7/30
Fri
1 stop
Copa Airlines
20h 05m
SFO - UIO
6/1
Tue
2 stops
Avianca
28h 27m
SFO - MDE
8/7
Sat
2 stops
American Airlines
21h 32m
SFO - UIO
8/9
Mon
1 stop
Delta
18h 23m
SFO - UIO
6/27
Sun
2 stops
American Airlines
25h 34m
SFO - UIO
5/11
Tue
2 stops
LATAM Airlines
26h 45m
SFO - GRU
3/27
Sat
2 stops
Aeromexico
21h 00m
SFO - UIO
Show more results
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