Find Deals on Flights from San Francisco to South America

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from San Francisco to South America

(Round-trip)
Depart: Sat Mar 11 2017 Return: Sun Mar 19 2017 Trip spans 8 days
Copa Airlines
Copa Airlines
SFO
CLO
16h 51m
1 stop
CLO
SFO
31h 51m
1 stop
Depart: Thu May 11 2017 Return: Fri May 19 2017 Trip spans 9 days
Major Airline
Major Airline
SFO
BOG
14h 30m
1 stop
BOG
SFO
23h 36m
1 stop
Depart: Mon Feb 27 2017 Return: Wed Mar 8 2017 Trip spans 10 days
American Airlines
American Airlines
SFO
BOG
14h 55m
1 stop
BOG
SFO
15h 49m
1 stop
Depart: Sun May 7 2017 Return: Tue May 16 2017 Trip spans 10 days
Avianca
Avianca
SFO
VVC
28h 13m
2 stops
VVC
SFO
32h 52m
2 stops
Depart: Wed May 31 2017 Return: Wed Jun 7 2017 Trip spans 8 days
Aeromexico
Aeromexico
SFO
MDE
22h 41m
1 stop
MDE
SFO
12h 59m
1 stop
Depart: Tue May 9 2017 Return: Wed May 10 2017 Trip spans 2 days
LATAM Airlines
LATAM Airlines
SFO
LIM
17h 05m
1 stop
LIM
SFO
38h 06m
2 stops
Depart: Thu Jun 1 2017 Return: Fri Jun 9 2017 Trip spans 9 days
Delta
Delta
SFO
BOG
29h 30m
1 stop
BOG
SFO
13h 42m
1 stop
Depart: Mon May 8 2017 Return: Mon May 15 2017 Trip spans 8 days
JetBlue
JetBlue
SFO
UIO
21h 36m
1 stop
UIO
SFO
15h 15m
1 stop
Depart: Wed Mar 29 2017 Return: Tue Apr 11 2017 Trip spans 14 days
United
United
SFO
LIM
21h 10m
1 stop
LIM
SFO
13h 58m
1 stop
Depart: Sun Feb 26 2017 Return: Wed Mar 15 2017 Trip spans 17 days
Major Airline
Major Airline
SFO
MDE
9h 17m
1 stop
MDE
SFO
24h 38m
1 stop
Depart: Tue Apr 25 2017 Return: Sat Apr 29 2017 Trip spans 5 days
Copa Airlines
Copa Airlines
SFO
CTG
9h 45m
1 stop
CTG
SFO
12h 43m
1 stop
Depart: Tue Feb 28 2017 Return: Wed Mar 8 2017 Trip spans 9 days
American Airlines
American Airlines
SFO
BOG
10h 55m
1 stop
BOG
SFO
15h 49m
1 stop
Depart: Thu Jun 22 2017 Return: Sun Jun 25 2017 Trip spans 4 days
Aeromexico
Aeromexico
SFO
MDE
32h 20m
1 stop
MDE
SFO
13h 04m
1 stop
Depart: Thu Apr 27 2017 Return: Thu May 11 2017 Trip spans 15 days
LATAM Airlines
LATAM Airlines
SFO
LIM
14h 15m
1 stop
LIM
SFO
18h 27m
2 stops
Depart: Thu Mar 9 2017 Return: Mon Mar 20 2017 Trip spans 11 days
Major Airline
Major Airline
SFO
CTG
17h 55m
1 stop
CTG
SFO
22h 53m
1 stop
Depart: Tue Aug 15 2017 Return: Wed Aug 23 2017 Trip spans 9 days
Delta
Delta
SFO
CTG
20h 25m
1 stop
CTG
SFO
32h 10m
1 stop
Depart: Mon Feb 27 2017 Return: Fri Mar 10 2017 Trip spans 12 days
Copa Airlines
Copa Airlines
SFO
MDE
11h 39m
1 stop
MDE
SFO
11h 52m
1 stop
Depart: Wed Mar 15 2017 Return: Tue Mar 21 2017 Trip spans 7 days
American Airlines
American Airlines
SFO
BOG
12h 55m
1 stop
BOG
SFO
15h 49m
1 stop
Depart: Tue Jul 4 2017 Return: Mon Jul 31 2017 Trip spans 28 days
Aeromexico
Aeromexico
SFO
MDE
20h 50m
1 stop
MDE
SFO
24h 04m
1 stop
Depart: Fri Apr 28 2017 Return: Thu May 11 2017 Trip spans 14 days
LATAM Airlines
LATAM Airlines
SFO
LIM
18h 10m
1 stop
LIM
SFO
18h 27m
2 stops
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

If you have more questions or if you have a bad price to report to us,
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Airports
Origin

San Francisco
$389
Destination

Cali
$389
Lima
$427
Medellin
$394
Cartagena
$396
Quito
$521
Bogotá
$393
Villavicencio
$419