Find Cheap Flights from San Francisco to South America

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from San Francisco to South America

(Round-trip)
Depart: Sat Jan 27 2018 Return: Sun Feb 4 2018 Trip spans 9 days
Multiple Airlines
Multiple Airlines
SFO
CLO
20h 02m
2 stops
CLO
SFO
15h 31m
2 stops
Depart: Tue May 22 2018 Return: Thu May 31 2018 Trip spans 10 days
Aeromexico
Aeromexico
SFO
MDE
22h 40m
1 stop
MDE
SFO
24h 19m
1 stop
Depart: Fri Feb 23 2018 Return: Sun Mar 4 2018 Trip spans 10 days
Copa Airlines
Copa Airlines
SFO
MDE
11h 48m
1 stop
MDE
SFO
10h 27m
1 stop
Depart: Sun Feb 25 2018 Return: Sat Mar 3 2018 Trip spans 7 days
Copa Airlines
Copa Airlines
SFO
MDE
9h 48m
1 stop
MDE
SFO
10h 07m
1 stop
Depart: Mon Feb 26 2018 Return: Wed Mar 7 2018 Trip spans 10 days
Aeromexico
Aeromexico
SFO
MDE
21h 34m
1 stop
MDE
SFO
23h 29m
1 stop
Depart: Mon Feb 26 2018 Return: Thu Mar 8 2018 Trip spans 11 days
Copa Airlines
Copa Airlines
SFO
MDE
9h 48m
1 stop
MDE
SFO
13h 00m
1 stop
Depart: Wed Jan 24 2018 Return: Sat Jan 27 2018 Trip spans 4 days
Aeromexico
Aeromexico
SFO
MDE
21h 34m
1 stop
MDE
SFO
14h 04m
1 stop
Depart: Thu Mar 1 2018 Return: Thu Mar 15 2018 Trip spans 14 days
Copa Airlines
Copa Airlines
SFO
MDE
10h 01m
1 stop
MDE
SFO
12h 02m
1 stop
Depart: Mon Jan 29 2018 Return: Thu Feb 1 2018 Trip spans 4 days
Aeromexico
Aeromexico
SFO
MDE
31h 00m
1 stop
MDE
SFO
14h 04m
1 stop
Depart: Thu Apr 5 2018 Return: Sun Apr 15 2018 Trip spans 11 days
Copa Airlines
Copa Airlines
SFO
MDE
12h 30m
1 stop
MDE
SFO
13h 02m
1 stop
Depart: Fri Feb 2 2018 Return: Sun Feb 11 2018 Trip spans 10 days
Aeromexico
Aeromexico
SFO
MDE
31h 00m
1 stop
MDE
SFO
14h 04m
1 stop
Depart: Thu Jan 18 2018 Return: Wed Jan 31 2018 Trip spans 14 days
Copa Airlines
Copa Airlines
SFO
BOG
14h 39m
1 stop
BOG
SFO
14h 13m
1 stop
Depart: Fri Feb 16 2018 Return: Fri Mar 2 2018 Trip spans 15 days
Aeromexico
Aeromexico
SFO
MDE
31h 00m
1 stop
MDE
SFO
14h 04m
1 stop
Depart: Sat Jan 20 2018 Return: Sat Feb 3 2018 Trip spans 15 days
Copa Airlines
Copa Airlines
SFO
BOG
10h 39m
1 stop
BOG
SFO
27h 33m
1 stop
Depart: Sat Feb 17 2018 Return: Fri Mar 2 2018 Trip spans 14 days
Aeromexico
Aeromexico
SFO
MDE
21h 34m
1 stop
MDE
SFO
14h 04m
1 stop
Depart: Sat Feb 3 2018 Return: Sun Feb 11 2018 Trip spans 9 days
Copa Airlines
Copa Airlines
SFO
BOG
18h 36m
1 stop
BOG
SFO
21h 07m
1 stop
Depart: Sun Feb 18 2018 Return: Fri Mar 2 2018 Trip spans 13 days
Aeromexico
Aeromexico
SFO
MDE
21h 34m
1 stop
MDE
SFO
23h 29m
1 stop
Depart: Mon Feb 5 2018 Return: Wed Feb 28 2018 Trip spans 24 days
Copa Airlines
Copa Airlines
SFO
BOG
13h 32m
1 stop
BOG
SFO
10h 40m
1 stop
Depart: Mon Feb 19 2018 Return: Fri Mar 2 2018 Trip spans 12 days
Aeromexico
Aeromexico
SFO
MDE
31h 00m
1 stop
MDE
SFO
14h 04m
1 stop
Depart: Sat Mar 3 2018 Return: Thu Mar 8 2018 Trip spans 6 days
Copa Airlines
Copa Airlines
SFO
BOG
13h 32m
1 stop
BOG
SFO
13h 48m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

San Francisco
$422
Destination

Cali
$422
Medellin
$422
Bogotá
$435