$105 Find Cheap Flights from San Francisco to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to South Carolina departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to South Carolina.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to South Carolina.
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Flight Deals

Cheap Flights from San Francisco to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$229
Myrtle Beach
Myrtle Beach1 stop$381
Greenville
Greenville1 stop$373
Columbia
Columbia1 stop$337
Florence
Florence1 stop$457
Charlotte
Charlotte2 stops$387
Charleston
Charleston1 stop$229
Myrtle Beach
Myrtle Beach1 stop$381
Greenville
Greenville1 stop$373
Columbia
Columbia1 stop$337
Florence
Florence1 stop$457
Charlotte
Charlotte2 stops$387

Book Cheap San Francisco to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to South Carolina

Wed, Sep 9 - Sat, Sep 12
Breeze Airways Logo
12:36 pm - 10:55 pm
SFO
-
CHS
7h 19m
1 stop
Breeze Airways Logo
6:20 am - 11:51 am
CHS
-
SFO
8h 31m
1 stop
$229Breeze Airways
Tue, Apr 21 - Tue, May 5
United Airlines Logo
5:00 am - 4:11 pm
SFO
-
CHS
8h 11m
1 stop
United Airlines Logo
1:19 pm - 6:38 pm
CHS
-
SFO
8h 19m
1 stop
$271United Airlines
Tue, Apr 28 - Wed, Apr 29
Southwest Logo
5:25 am - 9:05 pm
SFO
-
CHS
12h 40m
1 stop
Southwest Logo
1:15 pm - 10:45 pm
CHS
-
SFO
12h 30m
2 stops
$282Southwest
Tue, Apr 21 - Tue, May 5
Southwest Logo
5:25 am - 9:05 pm
SFO
-
CHS
12h 40m
1 stop
Southwest Logo
7:40 am - 7:55 pm
CHS
-
SFO
15h 15m
2 stops
$287Southwest
Wed, Sep 9 - Tue, Sep 15
Multiple Airlines Logo
12:36 pm - 10:55 pm
SFO
-
CHS
7h 19m
1 stop
Multiple Airlines Logo
6:14 pm - 9:13 am
CHS
-
SFO
17h 59m
1 stop
$288Multiple Airlines
Tue, Apr 21 - Tue, May 5
Delta Logo
10:30 pm - 8:51 am
SFO
-
CHS
7h 21m
1 stop
Delta Logo
9:38 am - 4:57 pm
CHS
-
SFO
10h 19m
1 stop
$291Delta
Mon, May 4 - Tue, May 12
American Airlines Logo
1:16 pm - 11:59 pm
SFO
-
CHS
7h 43m
1 stop
American Airlines Logo
4:25 pm - 9:04 pm
CHS
-
SFO
7h 39m
1 stop
$297American Airlines
Mon, May 4 - Tue, May 12
Southwest Logo
9:15 pm - 11:00 am
SFO
-
CHS
10h 45m
1 stop
Southwest Logo
6:40 am - 3:20 pm
CHS
-
SFO
11h 40m
2 stops
$302Southwest
Sat, May 23 - Sat, May 30
American Airlines Logo
9:52 pm - 8:16 am
SFO
-
CAE
7h 24m
1 stop
American Airlines Logo
6:03 pm - 10:49 pm
CAE
-
SFO
7h 46m
1 stop
$337American Airlines
Fri, Apr 24 - Fri, May 1
Delta Logo
11:39 pm - 11:29 am
SFO
-
CAE
8h 50m
1 stop
Delta Logo
1:59 pm - 8:24 pm
CAE
-
SFO
9h 25m
1 stop
$357Delta
Booking Insights

KAYAK's insights & trends for San Francisco to South Carolina flights

Get data-powered insights and trends into flights from San Francisco to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest San Francisco to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from San Francisco found in the last 72 hours was to Charleston, at $578 round-trip. The most popular route is from San Francisco (SFO) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $578.

What is the cheapest month to fly from San Francisco to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to South Carolina is August, when tickets cost $298 (return) on average. On the other hand, the most expensive months are November and April, when the average cost of round-trip tickets is $479 and $436 respectively.

How far in advance should I book a flight from San Francisco to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to South Carolina, you should book around 3 weeks before departure, which saves you about 31% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$105
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 8% increase in price.
Flight from San Francisco to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from San Francisco to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from San Francisco to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from San Francisco to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from San Francisco to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from San Francisco to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.1
Breeze AirwaysOverall score based on 271 reviews
6.6Food
8.3Boarding
6.6Entertainment
8.2Comfort
8.7Crew
Airline reviews

Our flight was delayed 7 hours. Due to a change in equipment we were downgraded from "Nicest" to "Nicer," even having to pay for a soft drink. Disappointing. To Breeze's credit that issued a $100 flight credit. A refund would have been more appreciated.

6.0 GoodJames, Feb 2026
RDU - RSW
Read more Breeze Airways reviews

Our flight was delayed 7 hours. Due to a change in equipment we were downgraded from "Nicest" to "Nicer," even having to pay for a soft drink. Disappointing. To Breeze's credit that issued a $100 flight credit. A refund would have been more appreciated.

Lost my luggage and terrible experience with customer service trying to track it down

10 hour delay with minimal updates. Couldn’t leave terminal and then ended up on redeye with a dirty broken plane. It is literally impossible to reach customer service via gate agent, app, phone, text or email.

I thought that I had pre-purchased carry-on luggage and was surprised when I tried to check in that I did not have it.

Flight departure was 90 min delayed, and the boarding experience was confused, stressful, and generally poor. Additionally, the wifi on the plane was malfunctioning for all but the final 15 min of the flight into ILM.

Great experience and In love flying in and out of Provo airport

You get what you pay for. It’s like a bus but flying. No frills, no snacks. Leg room was fine, boarding was good.

Overall good. Plenty of legroom and fairly comfortable seats. No issues with capacity and the overhead been even though most people brought several carry-ons on. I don’t think Breeze really enforces the pay for a carry-on rule.

Surprised at how much I enjoyed Breeze. Paid for the Nicer upgrade which made it closer in price to a flag ship carrier but with more comfortable seats and much more leg room. Crew was polite and since we brought our food no loss there. Would make the point that the ‘have to pay for a carry-on is BS’. Most people did not and had several. Still was plenty of room in the overheads.

Comfortable seating, adequate space available, nice to have USB port, polite crew.

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

Good but I prefer choose your own seat. With the new assigned seats they should board from the back I see no advantage to this new boarding. Just like every other airline

Flight boarded late after announcing on time boarding. Flight arrived only a little late despite late departure. Had trouble connecting to WiFi

The Southwest experience has definitely taken a dive from its early days. You can no longer deferentiate from other airlines. Air travel is too expensive. Southwest is no longer budget friendly. They have lost me as a loyal customer.

The charges were ridiculous for an hour flight and the turbulence was very scary.

The seats are now more narrow. I paid for front row the seats in the front are even more narrow than before.

The wifi on the plane is great. The only issue that I have is that I prefer an aisle seat and on my trips this week, I was either in the middle or window. If we can work to secure aisle seating, I will be thrilled. Nice trip.

Great flight but super high price. Glad it was a business trip and not personal

3 hour delay. Had to change plans and was still delayed.

We got exit row seats both flights. Everything was running on time

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

The landing was the worst I’ve experienced with a flight.

The crew, and fellow passengers, were super gracious and kind. There seemed to be plenty of bin space even though the plane was full. It’s nice to get a glass of wine with dinner in Premiere seating, and there was a lot of food.

Everything I mentioned earlier - the airbus was more comfortable indeed and the experience was further enhanced.

The plane was an older model, so it wasn’t as comfortable as others. The flight attendants were not helpful during onboarding. It was a full flight so there was chaos finding space for baggage.

Awesome! On time flight, early arrival, and a complimentary upgrade!

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

Staff were good. My seat was in need of repair, but for a short flight was not problematic. Usual basic snack and drink setup that you'll find on any US carrier. Over, a decent, basic flight.

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

it was a very short flight so my expectations were low.

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

The flight crew where really good. Better then the crew from BNE to SFO

left on time, reasonable boarding process arrived early luggage came out quickly

Pushed back only to get deplaned due to a tire damaged by ground crew. They did at least go pretty fast. The bathrooms should be banned under the Geneva convention. No room to even sit straight on the toilet. The under-seat entertainment units block what little leg room there is.

United airlines has the best customer experience from booking to arrival. I always fly United airlines. The mileage program is excellent

Delay after delay with little communication then AA lost my luggage and at airport would not assist just said scan this QR code to track your luggage and submit a claim. However QR code provided did not work so have to go back to airport

Dloght delayed by 2.5 hrs . Common theme in my last four american floghts

They are rarely on time! Very hard to plan your travels when flights or connections keep getting delayed.

My seat was assigned last row behind restrooms No legroom’s I’m very Pettit Still was not comfortable Food choice was excellent

The worst Airline ever. They centered my second flight and leave me in NY. They don’t have any representatives at the airport and they don’t respond to calls. Basically I got stuck. I will never purchase through there again.

The chicken wrap was tiny ($13 for what looked like a 1/3 of a normal wrap?) and disgusting.

Mediocre would be best description. Food bland. Seat biz class uncomfortable to sleep. Crew never dimmed lights completely in an overnight flight to Europe. Would avoid AA if possible.

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Massimo, flight attendant was very authentic, attentive - wonderful. Food/wrap was just okay.

Experience was great. The best part is the free Wi-Fi connection which helps me to work on the flight

Everything you need to know for your flight from San Francisco to South Carolina

Information on your arrival and departure airports