SAP - SCL

$606 Find Cheap Flights from San Pedro Sula to Santiago - Compare and Save

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Everything you should know

Cheapest round-trip
$930
Typical prices: $721-$932
Copa Airlines
Mon 3/19Sat 3/31
SAP - SCL • 1 stop
Cheapest one-way
$606
Typical prices: $366-$466
Avianca
Sat 11/10
SAP - SCL • 2 stops
Nonstop flights
Not available
There are currently no direct flights between San Pedro Sula and Santiago. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
20 weeks
in advance
Our data shows that travelers who book at least 20 weeks in advance save around 40% compared to booking last minute.
Insights
Insights
When to travel
April
Cheapest • 15% price drop
September
Most popular
Good to know
+1
Good to know
+1
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Flight Deals

Cheap Flights from San Pedro Sula to Santiago (SAP-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Pedro Sula to Santiago

Fri, Mar 19 - Wed, Mar 31
Copa Airlines Logo
1:38 am - 2:52 pmSAP  San Pedro Sula Ramon Villeda-SCL Santiago Arturo Merino Benitez
10h 14m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:06 pm - 1:06 pmSCL  Santiago Arturo Merino Benitez-SAP San Pedro Sula Ramon Villeda
24h 00m1 stop Panama City Tocumen Intl
$930Copa Airlines
Mon, Apr 19 - Sun, Apr 25
Copa Airlines Logo
1:38 am - 7:07 pmSAP  San Pedro Sula Ramon Villeda-SCL Santiago Arturo Merino Benitez
15h 29m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:58 pm - 12:29 amSCL  Santiago Arturo Merino Benitez-SAP San Pedro Sula Ramon Villeda
27h 31m1 stop Panama City Tocumen Intl
$930Copa Airlines
Fri, Nov 13 - Thu, Nov 26
Avianca Logo
9:30 am - 5:45 amSAP  San Pedro Sula Ramon Villeda-SCL Santiago Arturo Merino Benitez
17h 15m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
7:30 am - 6:50 pmSCL  Santiago Arturo Merino Benitez-SAP San Pedro Sula Ramon Villeda
14h 20m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$930Avianca
Thu, Apr 1 - Wed, Apr 14
Copa Airlines Logo
2:06 pm - 6:16 amSAP  San Pedro Sula Ramon Villeda-SCL Santiago Arturo Merino Benitez
13h 10m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:30 am - 1:06 pmSCL  Santiago Arturo Merino Benitez-SAP San Pedro Sula Ramon Villeda
27h 36m1 stop Panama City Tocumen Intl
$947Copa Airlines
Mon, Apr 12 - Fri, Apr 23
Copa Airlines Logo
1:38 am - 9:38 pmSAP  San Pedro Sula Ramon Villeda-SCL Santiago Arturo Merino Benitez
18h 00m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:30 am - 12:29 amSCL  Santiago Arturo Merino Benitez-SAP San Pedro Sula Ramon Villeda
14h 59m1 stop Panama City Tocumen Intl
$947Copa Airlines
Tue, Mar 30 - Fri, Apr 30
Copa Airlines Logo
1:38 am - 2:22 amSAP  San Pedro Sula Ramon Villeda-SCL Santiago Arturo Merino Benitez
21h 44m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:30 am - 12:29 amSCL  Santiago Arturo Merino Benitez-SAP San Pedro Sula Ramon Villeda
14h 59m1 stop Panama City Tocumen Intl
$947Copa Airlines
Sun, Jan 31 - Mon, Feb 8
Copa Airlines Logo
4:19 am - 11:41 pmSAP  San Pedro Sula Ramon Villeda-SCL Santiago Arturo Merino Benitez
16h 22m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:26 pm - 11:30 pmSCL  Santiago Arturo Merino Benitez-SAP San Pedro Sula Ramon Villeda
14h 04m1 stop Panama City Tocumen Intl
$964Copa Airlines
Sun, Jan 24 - Sun, Jan 31
Copa Airlines Logo
1:41 pm - 8:18 pmSAP  San Pedro Sula Ramon Villeda-SCL Santiago Arturo Merino Benitez
27h 37m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:20 pm - 11:30 pmSCL  Santiago Arturo Merino Benitez-SAP San Pedro Sula Ramon Villeda
14h 10m1 stop Panama City Tocumen Intl
$964Copa Airlines
Thu, Feb 11 - Sun, Feb 21
Copa Airlines Logo
4:19 am - 12:29 amSAP  San Pedro Sula Ramon Villeda-SCL Santiago Arturo Merino Benitez
17h 10m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:26 pm - 12:41 pmSCL  Santiago Arturo Merino Benitez-SAP San Pedro Sula Ramon Villeda
27h 15m1 stop Panama City Tocumen Intl
$964Copa Airlines
Mon, Nov 16 - Tue, Nov 24
Avianca Logo
8:10 pm - 3:10 pmSAP  San Pedro Sula Ramon Villeda-SCL Santiago Arturo Merino Benitez
16h 00m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
7:30 am - 8:35 amSCL  Santiago Arturo Merino Benitez-SAP San Pedro Sula Ramon Villeda
28h 05m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$975Avianca
Booking Insights

Price, demand and travel trends for San Pedro Sula to Santiago flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from San Pedro Sula to Santiago?

Round-trip flights from San Pedro Sula to Santiago typically range from $721 to $932. The lowest price found in the past 5 days was $930, on Copa Airlines.

What's the cheapest day of the week to fly from San Pedro Sula to Santiago?

Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from San Pedro Sula to Santiago. It’s 5% cheaper than the average day, while Friday is the most expensive, with prices 23% higher.

What’s the cheapest month to fly from San Pedro Sula to Santiago?

•April is the cheapest month to fly from San Pedro Sula to Santiago at $651 round-trip.
•March ($1,102) and November ($939) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 69% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from San Pedro Sula to Santiago the cheapest?

Flights from San Pedro Sula to Santiago are cheapest 20 weeks before departure. Booking in this window typically costs about 40% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for San Pedro Sula to Santiago flights

Low season

March

Cheapest flight

$606
Beat the crowds with an average 55% drop in travelers.
The most popular month to fly with an average 68% increase in travelers.
One-way flight from San Pedro Sula to Santiago

When to book flights from San Pedro Sula to Santiago

Are your dates flexible? Find out the best times to travel from San Pedro Sula to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your San Pedro Sula to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from San Pedro Sula to Santiago?

    Only Economy Class is available on flights from San Pedro Sula to Santiago.

  • How long is a flight from San Pedro Sula to Santiago?

    A nonstop flight from San Pedro Sula to Santiago takes 00m, covering 3,557 miles.

  • Do I need a passport to fly from San Pedro Sula to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a San Pedro Sula to Santiago flight?

    Round-trip flights from San Pedro Sula to Santiago range from $721 to $932, with an average of $764 over the past 12 months. Anything below $721 counts as a good deal.

  • How expensive are last-minute San Pedro Sula to Santiago flights?

    Last-minute fares on this route (booked within two weeks of departure) run 35% above the $764 route average. Book 20 weeks before departure for the lowest fares.

  • Have flight prices from San Pedro Sula to Santiago changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $930 to $4,546. That means the highest observed fare was about 5x higher than the lowest one.

  • How are flight prices from San Pedro Sula to Santiago looking right now?

    One-way fares from San Pedro Sula to Santiago are currently higher than usual. Average one-way flight prices are about $998, which is 155% above the typical average for this route.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates averaging $36 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from San Pedro Sula to Santiago?

    Flights from San Pedro Sula to Santiago usually depart from San Pedro Sula Ramon Villeda (SAP) and arrive at Santiago Arturo Merino Benitez (SCL).

  • Which airports do connecting flights from San Pedro Sula to Santiago pass through?

    Most connecting flights from San Pedro Sula to Santiago pass through Panama City Tocumen Intl (PTY), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from San Pedro Sula to Santiago?

    Yes. Flexible dates can save you up to 24% on flights from San Pedro Sula to Santiago. Thursday is the cheapest departure day at $727 round-trip on average, while Friday is the most expensive at $945, a difference of $218.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between San Pedro Sula and Santiago?

    Santiago is 3 hours ahead of San Pedro Sula (Chile Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santiago?

    Some of the most popular sights in Santiago are Estadio Nacional Julio Martinez Pradanos, Espacio Riesco Convention and Exhibition Center and Costanera Center. These are among the most viewed places in Santiago on KAYAK.

Your guide to booking San Pedro Sula to Santiago flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure and avoid flying on Friday. On this route, Thursday flights average $727, about $218 less than Friday fares (23% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 20 weeks before you fly. On this route, that window historically saves about 40% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your San Pedro Sula to Santiago trip for April. Fares historically average $651 round-trip in that month - typically $451 less than the most expensive month, which is March (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

More options for your flight from San Pedro Sula to Santiago

Complete your trip to Santiago with a hotel stay or car rental

Car rentals in Santiago
Hotels in Santiago
Vacations in Santiago