$150 Find Cheap Flights from John Wayne (Santa Ana) to Mexico - Compare and Save

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Cheap Flights from Santa Ana to Mexico

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Cancún
Cancún1 stop$521
Guadalajara
Guadalajara1 stop$312
Puerto Vallarta
Puerto Vallarta1 stop$459
León
León1 stop$520
Monterrey
Monterrey1 stop$422
Oaxaca
Oaxaca1 stop$673
Morelia
Morelia2 stops$570
Mérida
Mérida2 stops$710
Mazatlán
Mazatlán1 stop$537
Ixtapa
Ixtapa2 stops$660
Aguascalientes
Aguascalientes1 stop$577
La Paz
La Paz2 stops$723
Veracruz
Veracruz2 stops$625
Cancún
Cancún1 stop$521
Guadalajara
Guadalajara1 stop$312
Puerto Vallarta
Puerto Vallarta1 stop$459
León
León1 stop$520
Monterrey
Monterrey1 stop$422
Oaxaca
Oaxaca1 stop$673
Morelia
Morelia2 stops$570
Mérida
Mérida2 stops$710
Mazatlán
Mazatlán1 stop$537
Ixtapa
Ixtapa2 stops$660
Aguascalientes
Aguascalientes1 stop$577
La Paz
La Paz2 stops$723
Veracruz
Veracruz2 stops$625

Price, demand and travel trends for Santa Ana to Mexico flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Are flights from Santa Ana to Mexico cheaper or more expensive than last year?

Fares from Santa Ana to Mexico are running about 5% higher than they were around this time last year, averaging $641 round-trip.

What are the cheapest fares from Santa Ana to Mexico right now?

Here are the cheapest round-trip fares from Santa Ana to Mexico on KAYAK in the last week:

• Guadalajara Miguel Hidal (GDL) from $312
• Mexico City Benito Juarez (MEX) from $397
• San José del Cabo Los Cabos (SJD) from $459
• Puerto Vallarta Ordaz (PVR) from $459
• Cancun (CUN) from $521

What’s the cheapest month to fly from Santa Ana to Mexico?

February is the cheapest time of year to fly, with average fares of $619. Prices are highest in December, when average flight costs increase to around $765.

When is the best time to book flights from Santa Ana to Mexico?

Book your flights 10 weeks before your trip. KAYAK data collected over the past 12 months shows that booking in this window can save you around 46% compared to booking last-minute (within 2 weeks of departure).

Which airport in Mexico is the cheapest to fly to from Santa Ana?

Based on KAYAK data from the past 12 months, the cheapest airports to fly into Mexico are:

• Guadalajara Miguel Hidal (GDL) from $581
• Puerto Vallarta Ordaz (PVR) from $626
• San José del Cabo Los Cabos (SJD) from $649

What’s the cheapest day to fly from Santa Ana to Mexico?

Monday tends to be the cheapest day to fly from Santa Ana to Mexico, while Saturday is the most expensive. Fares run about 18% higher that day, based on the past 12 months of KAYAK data.

What's the cheapest time of day to fly from Santa Ana to Mexico?

Data from the past 12 months shows it's cheapest to fly to Mexico during the evening with average prices of $520. The night is the most expensive time to fly, with average prices of $941.

Key details for Santa Ana to Mexico flights

Low season

August

Cheapest flight

$150
Beat the crowds with an average 35% drop in travelers.
The most popular month to fly with an average 35% increase in travelers.
One-way flight from Santa Ana to Guadalajara

Your Santa Ana to Mexico flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Santa Ana to Mexico?

    Yes. Fares from Santa Ana to Mexico are low right now. As a rule of thumb, a round-trip under $569 (cheaper than most fares this year) is a good deal, so if you spot one at or below that, it's a good time to book.

  • How much should I budget for a flight from Santa Ana to Mexico?

    Over the past 12 months, round-trip fares from Santa Ana to Mexico have ranged from $569 to $804.

  • What are the main airports serving Mexico?

    Mexico has 62 airports. The three busiest are San José del Cabo Los Cabos (SJD) (47% of arrivals), Puerto Vallarta Ordaz (PVR) (21%) and Cancun (CUN) (18%).

  • What airlines fly nonstop from Santa Ana to Mexico?

    Based on the flight schedule for the next 3 months, just one airline regularly flies nonstop from Santa Ana to Mexico: Southwest.

  • Where in Mexico can I fly nonstop from Santa Ana?

    Based on the flight schedule for the next 3 months, you can fly nonstop from Santa Ana to two destinations: San José del Cabo and Puerto Vallarta.

  • Is it cheaper to fly with a layover from Santa Ana to Mexico?

    Yes. Nonstop flights from Santa Ana to Mexico average $646 over the past 12 months, but flights with a layover can cost less. The most affordable connecting airports are:

    • Las Vegas Harry Reid Intl (LAS) from $544
    • Denver Intl (DEN) from $622
    • San Francisco (SFO) from $643

  • How long is a flight from Santa Ana to Mexico?

    Nonstop flights take 2h 37m on average. The fastest scheduled flight takes 2h 20m, from Santa Ana J. Wayne/Orange Cnty (SNA) to San José del Cabo Los Cabos (SJD).

  • Which cabin classes are available on flights from Santa Ana to Mexico?

    On flights from Santa Ana to Mexico you can book Economy Class or First Class.

  • What are some popular landmarks in Mexico?

    KAYAK travelers' favorite landmarks in Mexico include:

    • El Ángel de la Independencia
    • Plaza de la Constitucion
    • Mexico City Stadium
    • Estadio GNP Seguros

  • What are the earliest and latest flights from Santa Ana to Mexico?

    The earliest nonstop flight from Santa Ana to Mexico departs at 7:20 am and the latest departs at 12:00 pm. Nonstop flights take about 2h 37m.

Your guide to booking Santa Ana to Mexico flights

Get tips on when to book, when to fly and what to know before your trip.
  • If you can plan ahead, the sweet spot for booking your flight is 10 weeks before your trip. KAYAK data shows fares in this window are around 46% lower than last-minute bookings (made within 2 weeks of departure). Not ready to commit? Set a Price Alert and we'll let you know when prices change.
  • If your travel dates are flexible, book your trip for February when flights are typically cheapest and avoid December when prices are at their highest.
  • Flying on Monday is usually the cheapest. Flights on Saturday cost about 18% more on average, so being flexible with your travel dates could help you save.
  • If you're looking to save, Guadalajara Miguel Hidal (GDL) is the cheapest airport to fly into from Santa Ana. If you have onward travel, don't forget to factor in the cost of your journey by train, bus or domestic flight.
  • Start your trip in Cancún, which is the most popular destination in Mexico. From there, it's easy to continue on to other popular destinations such as Playa del Carmen, Cabo San Lucas and Puerto Vallarta.
  • If you want the shortest trip, choose the Santa Ana to Mexico nonstop route. If you'd rather save money, the route via Las Vegas Harry Reid Intl (LAS) is usually the cheapest.

Reviews of the top 5 airlines serving from Santa Ana to Mexico

 
Need help choosing which airline to fly with from Santa Ana to Mexico? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
Alaska AirlinesOverall score based on 13086 reviews
8.5Crew
7.0Entertainment
7.8Comfort
8.1Boarding
7.0Food
Airline reviews

It was difficult in SNA to hear the gate announcements due to muffled voice and fire alarm ringing.

10.0 ExcellentDenise, Oct 2026
Read more Alaska Airlines reviews

It was difficult in SNA to hear the gate announcements due to muffled voice and fire alarm ringing.

This was the best flight I’ve ever been on- solely for the purpose that our pilot gave us a tour of the west coast. He didn’t need to do that but he did and it made the experience spectacular. Well done.

Service OK except could not make out much of what the pilot said when making announcements. Wish they would have had seat back screens. Charging ports were conveniently located. Overall very average experience. Far from the best, but I've had worse.

Our flught was rerouted to another airport 60 minutes from our destination. We were told we would get Lyft vouchers to get us to our original destination. We did get vouchers, but when we arrived at the rerouted airport, we realized the vouchers were for a Lyft ride from the starting airport to our original destination. We were lead to believe that once we arrived at the rerouted airport, we could use the voucher from there. Nope. So we got stuck with a $100, 1-hour Uber ride. The flight staff was annoying. We were seated near the rear, and for the entire flight, both attendants were gossiping about some drama on Facebook. And they weren't being quiet about it. The back dozen rows or so could easily hear their entire conversation. I've flown Alaska Airlines many times before and have never had problems. This was an awful experience.

Never had so many staff members be rude and disrespectful. I had a staff member sarcastically call me “girly” after making me wait 20 minutes to be seen by her. I was able to print my luggage tag and she told me I was too late to check luggage I said the system obviously disagrees. And you had me wait way too long while you asked every single passenger ahead of me about their Disney vacations. She wasted so much time to then say “girly your bag won’t make it on the plane” I’m not her girly I’m a full grown adult. She needs to learn a hell of a lot of respect

On time, friendly and professional staff and crew Very nice new terminal in Spokane

Wi-Fi cut out for a bit, then resumed. Otherwise flawless flight.

You need categories to denote when food and entertainment are not available.

Canceled flight. No communication of this prior. Rescheduled to next day. Our good seats we purchased months ago turned into last row middle. No apology, reason, nor compensation for time and $ spent.

I got the last seat on the plane, in the back in the corner against the window, and I paid a competitive price for my ticket several weeks before the flight.

Not exactly Southwest’s problem, but the new Burbank airport is not great. No restaurants open and tons of work still to be completed. Can’t believe they opened the airport in that condition.

Flight boarded 2.5 hours late (my second southwest flight of the day with late departure), the gate agent was grumpy and unhelpful. Said she was "tired so we aren't going to follow normal boarding order". No complaints about the actual flight crew.

I liked how it boarded fast. I do not like how the seats are just too narrow, and I’m not a big person.

Despite paying for an ‘upgraded’ seat in row 1, I had to put my luggage in the middle of the plane. Snacks were bleh and seat was small and uncomfortable and I am not large. Attendants were fine but not super helpful. Plane just seemed outdated.

Southwest has been a nightmare. Delayed flights, missed connections, systems down. Never again am I flying southwest.

had to check bag at gate when there was still overhead bin space. As usual the WIFI didn't really work.

The Southwest airline was ok. A big thank you to Kayak team (David), who worked with me on Sunday afternoon to rebook my travel from Burbank, CA, to CVG. My original flight on Sunday was delayed, so I had to cancel Sunday flight and rebook my travel to Monday. Could not have done it without help from David from Kayak team. Ante Soda GE Aerospace

Seated at front bulkhead for a smidge extra leg room away from home and on flight back home. Away crew was very proactive about assuring our carryons had space close behind us (because no seat in front of us our personal items had to be in a small bin overhead). They actively required passengers place overhead luggage on its side so more items could fit in bins. Home crew made no such efforts. I had to struggle back rows to get overhead bags upon landing, no crew help then either, and some disgruntled passengers as I and others retrieved our bags. There was a system that worked pretty well. The home bound crew just didn't feel like working.

Great flight, 47 passengers on a 180 seat plane. Stewardess was pleasant and cheerful.

The 700 model seating is too tight both seat size & leg room

Requested an aisle seat at the gate and got it. The staff so friendly

Had to deplane 2 x due to problems with plane. Delayed over 6 hours ans was given a $12 food credit which barely oaud for anything and limited to wear incoukd redeem.

more room in seats, larger snacks, more comms with delays

Seemingly unnecessary delays were compounded by a lack of communication from the flight crew which turned a four hour delay into an overly stressful experience.

My son’s suitcase was left behind at SFO and did not make the flight.

Flight team was great and we even arrived ahead of plan!

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

It was nt delta. It was aeromexo. Service was awful. They served a very small drink and NO snack for a 3hr and 35min flight. Then for the first 30 min of the flight is was talk and talk over head interruption the movie/ show i picked to watch.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Flight and seats were great. Food service was average at best. The real main problem we had is that we got cheeseburgers for the kids but the plates was extremely hot. Like ridiculously hot and the stewardess never said anything. Luckily or unluckily my wife touched the plate and was able to deal with it before the kids got burned.

Excellent. I had a medical emergency on flight SNA-ORD and the attendants were very helpful.

The air hostess was excellent. I have taken so many flight domestic and international, this is the first time the air hostess was so caring. She was a delight

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

It was great with United overall except for two things. 1) It was a 5-hour flight and we were with kids, so we were asking for extra snacks. They were extremely reticent to dole them out even though there wasn't any meal and the kids were starting to hit their limit towards the end. 2) Baggage didn't arrive until 80 minutes after we landed.

We had to deboard 2 times due to maintenance issues. They changed the plane, and then we got deviated to LAX due to maibtenance issues on the other plane, had to sleep at LAX and los a full day.

Not a great experience. We paid for the upgrade for premium economy seats and seated ourselves in very comfortable seats. Someone came along with the same seat on their boarding pass. The aircraft had been changed and as a result we were booted out and sent further back to small uncomfortable seats. After complaining we were moved to emergency row seats, which gave us more leg room but the seats don’t recline. For people in our 70’s we found having to sit upright from California to NJ very uncomfortable. Not sure why they chose to move senior citizens instead of the two people that were allowed to take the more comfortable seats. Not happy.

Breakfast was not loaded at SFO due to catering company change. Seems like a major airline at a major hub would have thought of something else or warned passengers to pick up food before boarding a 3 hour flight.

Very poor the plane itself was really old, slight smell that couldn’t be named. I didn’t even get a boarding pass UNTIL AFTER clearing security! Even then, they said when I get to my connected flight I’ll get my 2nd boarding pass there! A bit ridiculous!

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

the head jack on my seat didn't work and the power outlet didn't work for my seat

No food on 4.5 hour flight, wi-fi did not work. Terrible experience for a long haul flight.

Business class flight attendant was very good. But our flight was delayed two hours for a “mechanical” bathroom issue that literally took 5 minutes to fix. Our plane landed early from its previous flight but still waited for a mechanic to show up to fix an obvious minor issue for almost three hours. This caused us to miss our connecting flight. They put us up in a Days Inn that was 17 miles away from the airport that took a half hour of driving just to get to and this was at 11pm at night. Then when we finally got back on a plane after a full day delay they left our luggage back in the airport. This was an international flight, so no luggage or belongings after flying 8 hours to a different country. We will NEVER fly American Airlines again.

The WiFi didn’t work entire flight, couldn’t watch a movie. The recline button didn’t work

The flight was very smooth and the meal in business class was great.

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

The flight encountered a delay exceeding 4 hours. The food voucher issued was valued at $12, insufficient to cover our meal expenses. Consequently, I was unable to take my medication, leading to a drop in blood sugar levels and exacerbating my anxiety.

Flights were on time. That's the main consideration since I had to change planes. The entertainment was whatever you bring with you and the food (in Economy) is non-existant. Neither of those was a surprise.

The gate crew did try to help, however they lacked the information as to whether the flight will operate or not. Being delayed 6 hours and in a limbo on whether the flight will operate or not is not fun. The airline having staffing issues is not encouraging at all.

Flight was delayed and missed connecting flight. Did not give warning about delay until we showed up at the airport. Not good.

I love to be able to connect my own devices to the entertainment system. It works great!

More options for your flight from Santa Ana to Mexico

Complete your trip to Mexico with a hotel stay or car rental