$529 Find Cheap Flights from John Wayne (Santa Ana) to Sicily - Compare and Save

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1 adult, Economy, 0 bags

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Book Cheap Santa Ana to Sicily Plane Tickets

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Sicily

Sun, Feb 14 - Thu, Feb 18
United Airlines Logo
9:13 pm - 11:50 amSNA  Santa Ana J. Wayne/Orange Cnty-PMO Palermo Punta Raisi
53h 37m2 stops Newark Rome Fiumicino
United Airlines Logo
6:10 am - 8:28 pmPMO  Palermo Punta Raisi-SNA Santa Ana J. Wayne/Orange Cnty
23h 18m2 stops Rome Fiumicino Washington, D.C. Dulles Intl
$1,478United Airlines
Sun, Feb 14 - Thu, Feb 18
United Airlines Logo
9:13 pm - 11:50 amSNA  Santa Ana J. Wayne/Orange Cnty-PMO Palermo Punta Raisi
29h 37m2 stops Newark Rome Fiumicino
United Airlines Logo
6:10 am - 8:17 pmPMO  Palermo Punta Raisi-SNA Santa Ana J. Wayne/Orange Cnty
23h 07m2 stops Rome Fiumicino Newark
$1,478United Airlines
Sun, Feb 14 - Thu, Feb 18
United Airlines Logo
9:13 pm - 11:50 amSNA  Santa Ana J. Wayne/Orange Cnty-PMO Palermo Punta Raisi
53h 37m2 stops Newark Rome Fiumicino
United Airlines Logo
6:10 am - 8:28 pmPMO  Palermo Punta Raisi-SNA Santa Ana J. Wayne/Orange Cnty
47h 18m3 stops Rome Fiumicino Newark Washington, D.C. Dulles Intl
$1,498United Airlines
Sun, Dec 27 - Sun, Jan 3
Multiple Airlines Logo
7:01 pm - 5:45 pmSNA  Santa Ana J. Wayne/Orange Cnty-PMO Palermo Punta Raisi
61h 44m2 stops San Francisco Istanbul
Multiple Airlines Logo
6:45 pm - 9:53 amPMO  Palermo Punta Raisi-SNA Santa Ana J. Wayne/Orange Cnty
48h 08m2 stops Istanbul Seattle/Tacoma Intl
$2,139Multiple Airlines
Sun, Dec 27 - Sun, Jan 3
United Airlines Logo
6:30 pm - 11:50 amSNA  Santa Ana J. Wayne/Orange Cnty-PMO Palermo Punta Raisi
32h 20m3 stops San Francisco Washington, D.C. Dulles Intl Rome Fiumicino
United Airlines Logo
6:10 am - 10:27 pmPMO  Palermo Punta Raisi-SNA Santa Ana J. Wayne/Orange Cnty
25h 17m2 stops Rome Fiumicino Chicago O'Hare Intl
$3,444United Airlines
Sun, Dec 27 - Sun, Jan 3
Multiple Airlines Logo
12:30 pm - 9:15 amSNA  Santa Ana J. Wayne/Orange Cnty-PMO Palermo Punta Raisi
35h 45m3 stops Calgary Paris Charles de Gaulle Milan Linate
Multiple Airlines Logo
11:30 pm - 9:30 pmPMO  Palermo Punta Raisi-SNA Santa Ana J. Wayne/Orange Cnty
31h 00m3 stops Rome Fiumicino Reykjavik Keflavik Intl Seattle/Tacoma Intl
$3,556Multiple Airlines
Sat, Feb 6 - Wed, Feb 10
Multiple Airlines Logo
8:05 am - 11:50 amSNA  Santa Ana J. Wayne/Orange Cnty-PMO Palermo Punta Raisi
18h 45m2 stops Washington, D.C. Dulles Intl Rome Fiumicino
Multiple Airlines Logo
10:05 am - 10:30 pmPMO  Palermo Punta Raisi-SNA Santa Ana J. Wayne/Orange Cnty
21h 25m3 stops Rome Fiumicino Munich Franz Josef Strauss Chicago O'Hare Intl
$14,930Multiple Airlines
Booking Insights

Price, demand and travel trends for Santa Ana to Sicily flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What are the cheapest fares from Santa Ana to Sicily recently?

The cheapest fare from Santa Ana to Sicily in the last week was $1,478 round-trip, to Palermo Punta Raisi (PMO).

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Key details for Santa Ana to Sicily flights

Cheapest flight

$529
One-way flight from Santa Ana to Palermo

Your Santa Ana to Sicily flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Santa Ana to Sicily?

    Fares from Santa Ana to Sicily are above usual right now. If a round-trip fare drops below $911, it'll be a good deal. Set a Price Alert and KAYAK will let you know when prices change.

  • What are the main airports serving Sicily?

    Sicily has 8 airports. 100% of KAYAK users choose Palermo Punta Raisi (PMO) as their arrival airport.

  • Which airlines fly nonstop from Santa Ana to Sicily?

    Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Santa Ana to Sicily. However, United Airlines offers a one-stop option.

  • Which destinations in Sicily can I fly nonstop from Santa Ana?

    Based on the flight schedule for the next 3 months, there are no nonstop flights from Santa Ana to Sicily. The most popular destination you can reach with one stop is Palermo.

  • Which cabin classes are available from Santa Ana to Sicily?

    On flights from Santa Ana to Sicily you can book Economy Class or First Class.

  • What are some popular landmarks around Sicily?

    Sicily is home to many popular sights. KAYAK travelers' favorites include:

    • Mondello Beach
    • Teatro Massimo
    • Teatro Politeama
    • Quattro Canti

Your guide to booking Santa Ana to Sicily flights

Get tips on when to book, when to fly and what to know before your trip.
  • Start your trip in Palermo, the most popular destination in Sicily. From there, it's easy to continue on to other popular spots such as Taormina, Catania and Siracusa.

More options for your flight from Santa Ana to Sicily

Complete your trip to Sicily with a hotel stay or car rental

Car rentals in Sicily
Hotels in Sicily
Vacations in Sicily