SAF - STL

$282 Find Cheap Flights from Santa Fe to St. Louis - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$337
Typical prices: $324-$398
American Airlines
Sat 12/22Sun 12/30
SAF - STL • 1 stop
Cheapest one-way
$282
Typical prices: $372-$414
American Airlines
Wed 11/7
SAF - STL • 1 stop
When to travel
November
Cheapest • 11% price drop
July
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Dallas/Fort Worth (DFW)
Cheapest • Avg $394 (round-trip)
Denver Intl (DEN)
Shortest trip • 6h 04m (one-way)
Insights
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Cheap Flights from Santa Fe to St. Louis (SAF-STL)

 

Cheap flights from Santa Fe to St. Louis with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Tue, Dec 22 - Wed, Dec 30
American Airlines Logo
1:16 pm - 10:32 pmSAF  Santa Fe-STL Lambert-St Louis
8h 16m1 stop Chicago O'Hare Intl
American Airlines Logo
6:00 am - 12:18 pmSTL  Lambert-St Louis-SAF Santa Fe
7h 18m1 stop Chicago O'Hare Intl
$337American Airlines
Sat, Oct 31 - Sun, Nov 8
American Airlines Logo
6:05 am - 2:30 pmSAF  Santa Fe-STL Lambert-St Louis
7h 25m1 stop Dallas/Fort Worth
American Airlines Logo
5:00 am - 9:39 amSTL  Lambert-St Louis-SAF Santa Fe
5h 39m1 stop Dallas/Fort Worth
$352American Airlines
Sat, Jan 9 - Wed, Jan 13
United Airlines Logo
1:24 pm - 8:38 pmSAF  Santa Fe-STL Lambert-St Louis
6h 14m1 stop Denver Intl
United Airlines Logo
9:05 am - 5:11 pmSTL  Lambert-St Louis-SAF Santa Fe
9h 06m2 stops Chicago O'Hare Intl Denver Intl
$443United Airlines
Tue, Dec 22 - Tue, Dec 29
American Airlines Logo
1:16 pm - 10:32 pmSAF  Santa Fe-STL Lambert-St Louis
8h 16m1 stop Chicago O'Hare Intl
American Airlines Logo
8:22 pm - 12:18 pmSTL  Lambert-St Louis-SAF Santa Fe
16h 56m1 stop Chicago O'Hare Intl
$453American Airlines
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
1:26 pm - 8:59 pmSAF  Santa Fe-STL Lambert-St Louis
6h 33m1 stop Denver Intl
United Airlines Logo
4:39 pm - 8:29 pmSTL  Lambert-St Louis-SAF Santa Fe
4h 50m1 stop Denver Intl
$467United Airlines
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
10:30 am - 9:40 pmSAF  Santa Fe-STL Lambert-St Louis
10h 10m2 stops Denver Intl Chicago O'Hare Intl
United Airlines Logo
4:39 pm - 8:29 pmSTL  Lambert-St Louis-SAF Santa Fe
4h 50m1 stop Denver Intl
$473United Airlines
Sat, Jan 9 - Wed, Jan 13
United Airlines Logo
12:20 pm - 9:37 pmSAF  Santa Fe-STL Lambert-St Louis
8h 17m1 stop Chicago O'Hare Intl
United Airlines Logo
3:10 pm - 8:33 pmSTL  Lambert-St Louis-SAF Santa Fe
6h 23m1 stop Denver Intl
$482United Airlines
Sat, Oct 31 - Sun, Nov 8
United Airlines Logo
10:30 am - 9:40 pmSAF  Santa Fe-STL Lambert-St Louis
10h 10m2 stops Denver Intl Chicago O'Hare Intl
United Airlines Logo
4:39 pm - 8:29 pmSTL  Lambert-St Louis-SAF Santa Fe
4h 50m1 stop Denver Intl
$498United Airlines
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
10:30 am - 9:40 pmSAF  Santa Fe-STL Lambert-St Louis
10h 10m2 stops Denver Intl Chicago O'Hare Intl
United Airlines Logo
9:40 am - 8:29 pmSTL  Lambert-St Louis-SAF Santa Fe
11h 49m2 stops Chicago O'Hare Intl Denver Intl
$508United Airlines
Tue, Dec 22 - Wed, Dec 30
American Airlines Logo
11:42 am - 12:16 amSAF  Santa Fe-STL Lambert-St Louis
11h 34m2 stops Phoenix Sky Harbor Intl Dallas/Fort Worth
American Airlines Logo
6:00 am - 12:18 pmSTL  Lambert-St Louis-SAF Santa Fe
7h 18m1 stop Chicago O'Hare Intl
$539American Airlines

Price, demand and travel trends for Santa Fe to St. Louis flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Santa Fe to St. Louis?

Round-trip flights from Santa Fe to St. Louis typically range from $324 to $398. The lowest price found in the past 5 days was $337, on American Airlines.

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Key details for Santa Fe to St. Louis flights

Cheapest flight

$282
The most popular month to fly with an average 41% increase in travelers.
One-way flight from Santa Fe to St. Louis

When to book flights from Santa Fe to St. Louis

Are your dates flexible? Find out the best times to travel from Santa Fe to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santa Fe to St. Louis flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santa Fe to St. Louis?

    Only Economy Class is available on flights from Santa Fe to St. Louis.

  • How long is a flight from Santa Fe to St. Louis?

    There are currently no nonstop flights available from Santa Fe to St. Louis. Flights with 1 layover take between 5h 22m and 6h 04m in total, depending on the connection.

  • Do I need a passport to fly from Santa Fe to St. Louis?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Santa Fe to St. Louis flight?

    Round-trip flights from Santa Fe to St. Louis range from $324 to $398, with an average of $364 over the past 12 months. Anything below $324 counts as a good deal.

  • Have flight prices from Santa Fe to St. Louis changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $337 to $1,214. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Santa Fe to St. Louis looking right now?

    One-way fares from Santa Fe to St. Louis are currently lower than usual. Average one-way flight prices are about $348, which is 10% below the typical average for this route.

  • What car rental options are available at Lambert-St Louis Airport (STL)?

    Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates starting from around $31 for economy cars. Top options include:

    • Hertz
    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Payless

  • Which airports can I use when flying from Santa Fe to St. Louis?

    Flights from Santa Fe to St. Louis usually depart from Santa Fe (SAF) and arrive at Lambert-St Louis (STL).

  • Which airports do connecting flights from Santa Fe to St. Louis pass through?

    Connecting flights from Santa Fe to St. Louis most commonly pass through:

    • Dallas/Fort Worth (DFW) - 79% of one-stop connections
    • Denver Intl (DEN) - 21% of one-stop connections

  • Can I save money by using flexible dates for flights from Santa Fe to St. Louis?

    Yes. Flexible dates can save you up to 53% on flights from Santa Fe to St. Louis. Wednesday is the cheapest departure day at $324 round-trip on average, while Monday is the most expensive at $686, a difference of $362.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Santa Fe to St. Louis?

    Flying via Dallas/Fort Worth (DFW) gives the shortest average 1-stop total travel time at 5h 22m, compared with 6h 04m via Denver Intl (DEN).

  • What is the time difference between Santa Fe and St. Louis?

    St. Louis is 1 hour ahead of Santa Fe (Central Time vs Mountain Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in St. Louis?

    Some of the most popular sights in St. Louis are Busch Stadium, Enterprise Center and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

Your guide to booking Santa Fe to St. Louis flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Monday. On this route, Wednesday flights average $324, about $362 less than Monday fares (53% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Santa Fe to St. Louis trip for November. Fares historically average $324 round-trip in that month - typically $362 less than the most expensive month, which is October (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Lambert-St Louis Airport.

    • Renaissance St. Louis Airport Hotel
    • Drury Inn & Suites St. Louis Airport
    • DoubleTree by Hilton St. Louis Airport

More options for your flight from Santa Fe to St. Louis

Complete your trip to St. Louis with a hotel stay or car rental

Car rentals in St. Louis
Hotels in St. Louis
Vacations in St. Louis