SAF - STL

$304 Find Cheap Flights from Santa Fe to St. Louis - Compare and Save

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Fe to St. Louis departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to St. Louis

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Fe to St. Louis, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Fe to St. Louis, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$304
American Airlines
Tue 7/21Tue 7/28
SAF - STL • 1 stop
Cheapest one-way
$345
American Airlines
Sun 10/18
SAF - STL • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Santa Fe and St. Louis. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $403 (round-trip)
Shortest trip • 5h 28m (one-way)
Insights
Insights
Insights
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We hope you love your trip to St. Louis!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Fe to St. Louis (SAF-STL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Fe to St. Louis that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Fe to St. Louis

Tue, Jul 21 - Tue, Jul 28
American Airlines Logo
5:23 pm - 11:58 pm
SAF
-
STL
5h 35m
1 stop
American Airlines Logo
1:25 pm - 9:08 pm
STL
-
SAF
8h 43m
1 stop
$304American Airlines
Wed, Jul 8 - Sat, Jul 11
United Airlines Logo
6:00 pm - 11:57 pm
SAF
-
STL
4h 57m
1 stop
United Airlines Logo
5:10 am - 9:44 am
STL
-
SAF
5h 34m
1 stop
$334United Airlines
Sat, Dec 5 - Tue, Dec 8
United Airlines Logo
7:00 am - 12:43 pm
SAF
-
STL
4h 43m
1 stop
United Airlines Logo
4:30 pm - 10:01 pm
STL
-
SAF
6h 31m
1 stop
$426United Airlines
Sat, Dec 5 - Tue, Dec 8
United Airlines Logo
7:00 am - 12:43 pm
SAF
-
STL
4h 43m
1 stop
United Airlines Logo
1:08 pm - 10:01 pm
STL
-
SAF
9h 53m
2 stops
$473United Airlines
Tue, Jul 21 - Tue, Jul 28
United Airlines Logo
6:00 pm - 11:57 pm
SAF
-
STL
4h 57m
1 stop
United Airlines Logo
5:59 pm - 9:44 am
STL
-
SAF
16h 45m
2 stops
$496United Airlines
Wed, Jul 8 - Sat, Jul 11
American Airlines Logo
6:51 am - 1:53 pm
SAF
-
STL
6h 02m
1 stop
American Airlines Logo
9:44 am - 6:56 pm
STL
-
SAF
10h 12m
2 stops
$515American Airlines
Sat, Dec 5 - Tue, Dec 8
United Airlines Logo
7:00 am - 11:25 pm
SAF
-
STL
15h 25m
2 stops
United Airlines Logo
1:08 pm - 10:01 pm
STL
-
SAF
9h 53m
2 stops
$520United Airlines
Sat, Nov 14 - Tue, Nov 17
United Airlines Logo
3:20 pm - 8:34 pm
SAF
-
STL
4h 14m
1 stop
United Airlines Logo
1:39 pm - 5:10 pm
STL
-
SAF
4h 31m
1 stop
$577United Airlines
Sat, Nov 14 - Tue, Nov 17
United Airlines Logo
7:00 am - 12:37 pm
SAF
-
STL
4h 37m
1 stop
United Airlines Logo
6:00 am - 5:10 pm
STL
-
SAF
12h 10m
2 stops
$587United Airlines
Tue, Jul 7 - Fri, Jul 10
United Airlines Logo
6:00 pm - 11:57 pm
SAF
-
STL
4h 57m
1 stop
United Airlines Logo
1:38 pm - 2:44 pm
STL
-
SAF
26h 06m
1 stop
$627United Airlines
Booking Insights

KAYAK's insights & trends for Santa Fe to St. Louis flights

Get data-powered insights and trends into flights from Santa Fe to St. Louis to help you find the cheapest flights, the best time to fly and much more.

What is the most popular layover airport when flying from Santa Fe to St. Louis?

Percentage of 1-stop round-trip flights from Santa Fe to St. Louis chosen by KAYAK users via each layover airport in the last 12 months (only includes trips with the same layover airport on both legs).

Dallas (DFW) is the top choice – 59% of KAYAK users who clicked on 1-stop flights from Santa Fe to St. Louis picked an itinerary connecting there.

What is the cheapest layover airport when flying from Santa Fe to St. Louis?

Average round-trip price for 1-stop flights from Santa Fe to St. Louis clicked by KAYAK users in the last 12 months (only includes trips with the same layover airport on both legs).

Flights via Denver (DEN) offer the most affordable fares, with an average round-trip price of $403.

Which layover airport offers the shortest total travel time from Santa Fe to St. Louis?

Shortest average total travel time for 1-stop one-way flights from Santa Fe to St. Louis via different layover airports, based on KAYAK user data from the last 12 months.

Consider flying via Dallas (DFW) for the shortest journey. The average one-way travel time for flights connecting there is 5h 28m.

Which layover airport has the quickest connection when flying from Santa Fe to St. Louis?

Average layover duration at different layover airports for 1-stop one-way flights from Santa Fe to St. Louis, based on KAYAK user data from the last 12 months.

If you prefer a quick connection, Dallas (DFW) often has the shortest layovers from Santa Fe to St. Louis, with an average of 1h 29m.

Good to know

Cheapest flight$304
Flight from Santa Fe to St. Louis

When to book flights from Santa Fe to St. Louis

Are your dates flexible? Find out the best times to travel from Santa Fe to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santa Fe to St. Louis

  • What is the cheapest flight from Santa Fe to St. Louis?

    In the last 5 days, the lowest price for a flight from Santa Fe to St. Louis was $345 for a one-way ticket and $426 for a round-trip.

  • Do I need a passport to fly between Santa Fe and St. Louis?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Santa Fe to St. Louis?

    Santa Fe airport is called Santa Fe and the only airport in St. Louis is Lambert-St Louis.

  • Which aircraft models fly most regularly from Santa Fe to St. Louis?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santa Fe to St. Louis?

    oneworld is the only airline alliance operating flights between Santa Fe and St. Louis.

  • How does KAYAK find such low prices on flights from Santa Fe to St. Louis?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Fe to St. Louis.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Fe to St. Louis?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to St. Louis from Santa Fe is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Fe to St. Louis?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to St. Louis with an airline and back to Santa Fe with another airline. Booking your flights between Santa Fe and STL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Fe to St. Louis?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to St. Louis from Santa Fe up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santa Fe to St. Louis

 
See real verified KAYAK customer reviews for airlines flying from Santa Fe to St. Louis. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Fe to St. Louis? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11774 reviews
6.8Entertainment
7.5Boarding
7.9Crew
7.2Comfort
6.4Food
Airline reviews

We called Kayak for a change due to the TSA situation in Atlanta. What we got was a canceled return flight (in error) and we had to find the mistake. Not happy with Kayak who blamed it on AA.

2.0 MediocreJohn, Mar 2026
PHX - STL
Read more American Airlines reviews

We called Kayak for a change due to the TSA situation in Atlanta. What we got was a canceled return flight (in error) and we had to find the mistake. Not happy with Kayak who blamed it on AA.

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!

Improvements in communication and empathy are absolutely necessary for American Airlines staff (top down). It’s like they are numb to the needs of their customers.

I like the speed of boarding and deplaning and the fact that everything was on time. The crew (attendants) were probably quite new and did not begin the in cabin service until 30 min before landing even though there was little to no air turbulence for the last 1.5 hours of the flight. It made for a mad scramble at the end to get trash collected and carts stowed before touch down.

The flights was delayed by hours and it was the firmest landing I have experienced in my life. My back is still sore.

I did like the employee's, they are very friendly and all smiled most of the time, Overall, from checking in bags to getting on plane, not enough employees to be able to get all on the plane, therefore I was not able to get on the plane, due to no one wea there for me to check in my bag, so I decided to go thru the security point and by the time they were done with my bags, I was told that my bag cannot be checked in, and then found out that the lady that does the check in was boarding the customers onto the plane, she said that she was going back and fourth, there for was not able to get on the plane, which changed all my flights by the time I got to Dallas, I was on standby 3 times, and wasn't sure about being able to get on the fourth plane, so ended up buying another plane ticket, so I could make my destination on time.

Not sure about entertainment as I didn't use any, so maybe there should be an NA option on this survey. Otherwise everything was just as it should be. Of course I wish planes were more comfortable and had seats that would tilt back further.

American Airlines “Randy” questioned why I needed preboarding and denied my request for same. Then Randy attempted to berate me when I boarded with my group. I was seated in an exit roll with a young man with a disability that exhibited difficulty controlling and settling himself. But Tandy questioned my disability. The flight was horrible. It was overpacked.

Everything you need to know for your flight from Santa Fe to St. Louis

Information on your arrival and departure airports