$90 Find Cheap Flights from South Carolina to Missouri

1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Missouri

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 20% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Useful Info

Good to know

Low seasonJanuary
High seasonJuly
Cheapest flight$90
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Charlotte to St. Louis

FAQs for booking flights from South Carolina to Missouri

  • How does KAYAK find such low prices on flights from South Carolina to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from South Carolina to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from South Carolina to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from South Carolina to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • Which is the cheapest airport to fly into in Missouri?

    Prices will differ depending on the departure airport, but generally, the cheapest airport to fly to in Missouri is Lambert-St Louis Airport (STL), with an average flight price of $317.

  • What is the cheapest day to fly to Missouri?

    Based on KAYAK data, the cheapest day to fly to Missouri is Thursday where round-trip tickets can be as cheap as $336. On the other hand, the most expensive day to fly is Saturday, where round-trip prices are $646 on average.

  • What is the cheapest time of day to fly to Missouri?

    The cheapest time of day to fly to Missouri is generally at night, when round-trip flights cost $372 on average. Morning departures are around 67% more expensive than evening flights, on average. The most expensive time of day to fly to Missouri is generally in the morning, which is peak travel time and where the average cost of a ticket is $646.

  • What is the cheapest flight to Missouri?

    The cheapest ticket to Missouri from South Carolina found in the last 72 hours was to St. Louis, at $285 round-trip. The most popular route is Charleston (CHS) to St. Louis (STL) and the cheapest round-trip airline ticket found on this route in the last 72 hours was $285.

  • What is the cheapest month to fly from South Carolina to Missouri?

    The cheapest month for flights from South Carolina to Missouri is July, when tickets cost $288 (return) on average. On the other hand, the most expensive months are April and January, when the average cost of round-trip tickets is $498 and $338 respectively.

  • How far in advance should I book a flight from South Carolina to Missouri?

    To get a below average price on the flight from South Carolina to Missouri, you should book around 4 weeks before departure. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

  • How long is the flight to Missouri?

    An average nonstop flight from South Carolina to Missouri takes 7h 13m, covering a distance of 759 miles. The shortest route is Charlotte (CLT) to St. Louis (STL) with an average flight time of 1h 54m.

  • What are the most popular destinations in Missouri?

    Based on KAYAK flight searches, the most popular destination is St. Louis (42% of total searches to Missouri). The next most popular destinations are Kansas City (31%) and Springfield (24%). Searches for flights to Columbia (1%) and to Joplin (1%) are also popular.

Reviews of the top 5 airlines serving from South Carolina to Missouri

 
Need help choosing which airline to fly with from South Carolina to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4279 reviews
8.0Comfort
7.6Entertainment
8.2Boarding
8.6Crew
7.1Food
Airline reviews

Southwest is Southwest. No frills. If you're luck enough to get a happy crew (we did), then it makes for a nicer flight.

10.0 ExcellentMichael, Jun 2025SMF - SEA
Read more Southwest reviews

Southwest is Southwest. No frills. If you're luck enough to get a happy crew (we did), then it makes for a nicer flight.

Southwest is typically delayed, and it gets wearisome. It is no longer a discount airline and you get way less than you pay for when it comes to comfort and Ce.

We sat on the plane on the tarmac for 4 hours.

I'm not a fan of Southwest's model. I don't like the herding style of boarding.

Flight crew and cabin crew were great. I had to rearrange flights because my original flight was 3hrs delayed for weather, the rub is the flight I moved to boarded on time then we sat at the gate for 2 hours because scheduling stole our first officer for another flight, TWICE. Then our actual FO was an hour delayed. To make it worse my original flight went from a 3 hour delay to departing 15min EARLY. Just poor scheduling operations all around.

Bring back peanuts Take our drink orders when were all seated, especially after you switch to assigned seating.

Staff was far less than helpful at all times. Departure and arrival times mean nothing to Southwest. Extremely disappointed, will never fly with them again, and I’ll be sure to share my experience with all.

It is southwest seat was ok. Not the most comfortable seat

I’ve always loved Southwest. No issues at all. I was flying standby and the gate agent was extremely friendly and helpful. Boarding was smooth and I was able to get a window seat in the emergency exit row. Crew was fantastic! They were very professional and accommodating. We had to divert from our destination due to weather but the flight crew kept everyone at ease and informed us of all pertinent information. Excellent flight

The price of the tickets isn't matching the flight experience. No matter how long the flight is, you're only getting pretzels. The flight attendants looked unkept and over it.

I like for how they process during check in. It was very smoothly.

The flight was scheduled for 2:30 PM. Early in the morning we got a text message saying the flight was delayed and rescheduled for 3:00 PM. We got to the airport with that in mind. Then we got a message during check-in at the flight was rescheduled again for 2:30 PM. We almost missed our flight. In fact, our bags Were told that they would not make it. At the end, everything worked out. But it is very stressful.

Most aspects were good however if they assign boarding zones they ought to enforce them or why bother? My luggage from SAN-JFK-MAD was lost in NY so I without my main bag for two days upon arrival in Spain. They were helpful in tracking it and eventually delivered it to my hotel. The flub was because of a delay upon arrival in NYC. I had booked 2 1/2 hours between flights but we had to hold on the taxiway for an hour after landing while waiting for a clear gate which likely caused the baggage error.

Excellent check-in. Crew was good. Excellent communication from flight deck.

Great overall. There was a bit of turbulence so they could only serve water because too much turbulence for the carts. Was glad they prioritized safety though

Excellent flight, the planes were newer, they did a nice job with boarding, great service overall.

Great service. Flight was delayed while we sat on the runway for a couple of hours. Weather related. Staff made is very bearable. The steward servicing the first class cabin was exceptional. Thank you! 💗

5 hours of delay that could've been much shorter if Delta had taken the 1 hour delay they imposed on the flight before boarding to run any of the plane checks required for flight to find the hydraulic issue that required nearly 3 hours to fix. $24 of meal credit buys a sandwich and a soft drink. Poor communication within the terminal about what gate we'd be re-boarding from and when we'd be re-boarding.

Amazing flight! I have never noticed the uniforms of the attendants before in twenty years of flying except today when one female had the most amazing dress on. It was beautifully designed and showed she was in charge. I never dreamed I would google who designed Delta uniforms . The ultimate compliment is when another woman admires your outfit. . I hope your designer puts it on the market

It would be nice if was given wires ear buds. Overall was a good experience was able to sleep on the plane

Gate agent did not hold flight for connection, provided no assistance to get new flight

Evidently, my seat had the only broken TV. I couldn’t plug it in, get it to come on, or watch anything, and of course, no one could fix it while we were on the plane. The service was good and the boarding was quick

United airlines, mediocre at best. No issues , nothing great . Worked for me

it was so bad. I tried to board my flight from vancouver to saskatoon. And to my surprise they did not board me cause the flight was changed and no email was send to me. and on my boarding pass which i got from seattle says different flight. I did not knew anyone from Vancouver, air canada crew was rude, i asked for today flight but they were rude and i had early morning dental appointment in saskatoon. I was so much in pain and my whole day is wasted today. and i suffered alot. They did provide me hotel but they did not provide me any food. I am really really disappointed first time had so bad experience with air canada. I may think twice to book it again. If i can get any reply or any composition that would be great. Thanks

It was fine, definitely older planes with no charging or anything. There’s no entertainment set up on board, but it is nice that they allow you to access the in flight entertainment from your phone without having to pay for the Wi-Fi and they do offer free texting.

Boarding was mayhem. Late boarding by 15 minutes because of lack of staff (missing 1 flight attendant. We had to wait for an arrival of another plane before we could board). Flight was a little rough, but cannot blame on airlines.

Impressed with the service despite turbulence because of the weather. Both flights arrived before their scheduled times.

Very comfortable (upgraded to business class). The audio on my screen didn’t work, but I managed to play the audio through my phone while watching the screen.

Great experience…left a bit behind schedule but made up fir that in the air and landed 10 minutes early 😁

I was supposed to be on business class at first class from Denver back to Miami due to weather changes. I missed my connection and it’s put on a flight to Fort Lauderdale. Instead of honoring my business class/1st class ticket, they put me in coach, but there were two first class seats open. I think it’s absolutely disgusting that I paid for first class $1300 ticket and they put me in economy and they had to open seats available and I have still not been refunded the difference. I ended up having to eat a snack box instead of the meal I was supposed to get and did not get home till 2 AM so I think that’s a little pathetic that I had to live off crackers for dinner And my poor dog ate some cheese and salami. Oh yes, apparently when they switched me to the new flight they forgot to mention I had a service dog

Loved the staff, boarding and drink options! Wish the comfort of the seat could have been better nevertheless

The chair cushions may need an upgrade. I have been noticing they are so worn out, thin so you’d sit in a dip 😄. Other than that, all was an enjoyable trip. Thanks AA!

I’m impressed that we were on time in Sacramento after having a late departure in Newark and our made it. The staff was friendly and warm.

Cramped seats. FAA should make airlines have more legroom, for even short people complain

5.5 hour delay with no explanation on why, along with no proactive effort to reaccomodate me.

It was one of my worst flight ever. First they were changing the gate for at least 4 times, changing from gate D7 to D12 to D44. Considering the size of the Miami Airport, we are talking about long distance and the train at the airport was not working. Then the flight was delayed around one hour. Then finally we boarded into the plane and when everybody was seated, there was an announcement that there is an issue with one of the tire of the plane, so we all had to get out of the plane with our belongings, to replace the tire. So we had around 2.5-hour delay

Most miserable flight ever. We waited almost 2 hours on the runway because the flight was oversold. American offered $1200 credit. Then there was some nonsense about weight distribution. Ridiculous. No food for 8 plus hours on the flight. I will be writing a letter.

Honestly, I haven’t flown American in years, probably due to the pandemic and my being unable to travel for certain periods in the last two years, but it was a good experience to dig out or obtain a new American Airlines account after many years of traveling for business with American in the past.

The plane was probably full boarding was easy. We were able to check our carry-on luggage for free. It was a return flight through Philly to LA. Never saw a stewardess do a demonstration of emergency Procedures. I think my flight was pretty full

Plane, flight, crew, captain were all great. The first flight had a Chipotle box lunch...delicious.

It was absolutely awesome. The crew was welcoming to all, not just the first class. They were full of energy. The in-cabin music was an excellent choice, not boring like most airlines. We were ready for takeoff ahead of time. Pilots were great. Smooth takeoff and landing. The plane was beautiful and nicely cleaned. This was truly a fantastic flight. I fly Delta and American all the time. I was apprehensive about Spirit. I will definitely be looking for Spirit first. Thanks for a great experience.

Didn't like size of seats. Found charges for checked luggage and carry on too high

Great! We boarded on time! Everything went so smoothly! The flight was so smooth

Spirit gets you there; it's no worse than any other aircraft, all things considered. (It's not like everyone else is such a hero). But - holy moses - do they nickel and dime you to absolutely every nickel - I was really expecting to have to pay to use the bathroom. And when the captain comes on with a 5 minute sales pitch about getting "points", that was like something on Bizarro world. Other than that, everyone else was professional and worked hard to get us from point A to point B. I'm not loving all the "self-service" stuff but there it is - just when the machines don't work you don't have anyone to talk to.

Boarding was a breeze, however, two of the flights that I boarded with Spirit did not have Wi-Fi available.

Seats uncomfortable, hard to check luggage, etc. It was like the last flight out of Hanoi

Need screens for tv/movies. Seats are more cramped than any other airlines. Seats are hard. They don’t recline. And in flight time should not be used for sales pitches.

Good experience except for the drunk woman who was with a child. Sad

The ease of booking the flight was very good. Speaking with customer service was also good. However, the crew people are unfriendly and unwelcoming which I found this as unprofessional. As far as comfort it was mediocre. This was my first time flying Spirit and I chose them because of the flight times met my needs and my budget. However, I would be reluctant to fly on Spirit again. In addition, if the crew were more friendly and at least appeared somewhat happy and welcoming personally it would probably make the experience of flying with Spirit better.

Tell them to chose a better, less bumpy route :( my seat had no window all the way at the end 😔

Book cheap flights from South Carolina to Missouri

Recent round-trip flight deals

8/28Thu
1 stopSouthwest
7h 05mCLT-MCI
9/1Mon
1 stopSouthwest
4h 30mMCI-CLT
$144
8/28Thu
2 stopsSouthwest
9h 10mCLT-MCI
9/1Mon
1 stopSouthwest
4h 30mMCI-CLT
$150
9/18Thu
1 stopSpirit Airlines
15h 45mCLT-STL
9/21Sun
1 stopSpirit Airlines
6h 15mSTL-CLT
$190
7/10Thu
2 stopsSpirit Airlines
23h 12mCLT-STL
7/14Mon
1 stopSpirit Airlines
5h 37mSTL-CLT
$204
7/22Tue
nonstopAmerican Airlines
1h 53mCLT-STL
7/29Tue
nonstopAmerican Airlines
1h 58mSTL-CLT
$217
9/4Thu
1 stopDelta
4h 45mGSP-STL
9/11Thu
1 stopDelta
6h 29mSTL-GSP
$217
9/4Thu
1 stopAmerican Airlines
8h 13mCLT-STL
9/6Sat
nonstopAmerican Airlines
1h 56mSTL-CLT
$227
7/1Tue
1 stopDelta
6h 26mCLT-MCI
7/4Fri
1 stopDelta
4h 07mMCI-CLT
$251
7/1Tue
2 stopsUnited Airlines
8h 14mCLT-MCI
7/4Fri
2 stopsUnited Airlines
7h 02mMCI-CLT
$261
9/5Fri
1 stopUnited Airlines
5h 08mGSP-MCI
9/6Sat
1 stopUnited Airlines
8h 00mMCI-GSP
$264

Search by stops

Search by airline

Search by price

Recent one-way flight deals

7/15Tue
1 stopFrontier
5h 44mCLT-STL
$90
7/24Thu
1 stopSpirit Airlines
16h 23mCLT-STL
$92
9/4Thu
nonstopSouthwest
2h 00mCLT-STL
$99
8/21Thu
1 stopDelta
5h 46mCHS-MCI
$104
8/25Mon
1 stopSouthwest
4h 10mCLT-STL
$108
8/19Tue
2 stopsUnited Airlines
10h 05mCHS-MCI
$109
7/19Sat
1 stopAmerican Airlines
4h 55mSAV-STL
$120
8/9Sat
1 stopDelta
6h 32mCHS-MCI
$121
8/16Sat
1 stopUnited Airlines
6h 26mCLT-STL
$123
8/23Sat
2 stopsAmerican Airlines
8h 22mCHS-MCI
$131

Search by stops

Search by airline

Search by price

Last minute flights from South Carolina to Missouri

Last minute flight, train and bus deals

6/21Sat
nonstopAmerican Airlines
2h 01mCLT-STL
8/23Sat
nonstopAmerican Airlines
1h 58mSTL-CLT
$237
6/21Sat
multi-stopAmerican Airlines
6h 04mCLT-STL
8/23Sat
nonstopAmerican Airlines
1h 58mSTL-CLT
$247
6/18Wed
multi-stopDelta
4h 44mCLT-MCI
6/23Mon
multi-stopDelta
5h 33mMCI-CLT
$295
6/18Wed
multi-stopDelta
7h 21mCLT-MCI
6/22Sun
multi-stopDelta
6h 00mMCI-CLT
$305
6/21Sat
multi-stopUnited Airlines
9h 30mCLT-STL
8/23Sat
multi-stopUnited Airlines
6h 58mSTL-CLT
$332
6/21Sat
multi-stopSouthwest
4h 05mCLT-STL
8/23Sat
multi-stopSouthwest
8h 20mSTL-CLT
$342
6/18Wed
multi-stopUnited Airlines
5h 22mCLT-STL
6/24Tue
multi-stopUnited Airlines
8h 05mSTL-CLT
$352
6/18Wed
multi-stopSouthwest
6h 30mCLT-MCI
6/21Sat
multi-stopSouthwest
4h 50mMCI-CLT
$404
6/21Sat
multi-stopSpirit Airlines
29h 50mCLT-MCI
6/23Mon
multi-stopSpirit Airlines
15h 50mMCI-CLT
$703
6/19Thu
multi-stopSpirit Airlines
17h 42mCLT-MCI
6/22Sun
multi-stopSpirit Airlines
18h 24mMCI-CLT
$881

Search by stops

Search by airline

Search by price

Everything you need to know for your flight to Missouri

Cabin class types available on flights to South Carolina

Cabin classes available on flights to South Carolina. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.