$99 Find Cheap Flights from Missouri to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Missouri to South Carolina departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 21% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Useful Info

Good to know

Low seasonJanuary
Cheapest flight$99
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from St. Louis to Charlotte

FAQs for booking flights from Missouri to South Carolina

  • How does KAYAK find such low prices on flights from Missouri to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Missouri to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Missouri to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Missouri to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Missouri to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Missouri to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Missouri to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Missouri to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • How many airports are there in South Carolina?

    There are 6 airports in South Carolina. The busiest airport is Charleston Municipal Airport (CHS), with 40% of all flights arriving there.

  • What is the cheapest day to fly to South Carolina?

    Based on KAYAK data, the cheapest day to fly to South Carolina is Saturday where round-trip tickets can be as cheap as $471. On the other hand, the most expensive day to fly is Saturday, where round-trip prices are $471 on average.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the morning, when round-trip flights cost $471 on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $471.

  • What is the cheapest flight to South Carolina?

    The cheapest ticket to South Carolina from Missouri found in the last 5 days was to Charleston, at $261 round-trip. The most popular route is Kansas City (MCI) to Charleston (CHS) and the cheapest round-trip airline ticket found on this route in the last 5 days was $261.

  • What is the cheapest month to fly from Missouri to South Carolina?

    The cheapest month for flights from Missouri to South Carolina is July, when tickets cost $77 (return) on average. On the other hand, the most expensive months are June and December, when the average cost of round-trip tickets is $148 and $148 respectively.

  • How far in advance should I book a flight from Missouri to South Carolina?

    To get a below average price on the flight from Missouri to South Carolina, you should book around 6 weeks before departure, which saves you about 32% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

  • How many cities have direct flights to South Carolina?

    From Missouri, there are direct flights to South Carolina from 2 cities. The city with the most direct flights is St. Louis, with 13 direct flights each week.

  • How many direct flights to South Carolina are there each day?

    There are around 3 direct flights from within Missouri to South Carolina every day. Most flights (63%) depart in the afternoon.

  • How many direct flights to South Carolina are there each week?

    Each week there are around 16 direct flights from within Missouri to South Carolina. The most common day for departures is Saturday, with 31% of flights taking off on this day.

  • How long is the flight to South Carolina?

    An average nonstop flight from Missouri to South Carolina takes 6h 27m, covering a distance of 758 miles. The shortest route is St. Louis (STL) to Charlotte (CLT) with an average flight time of 1h 45m.

  • How many long-haul flights are there to South Carolina each week?

    There are not any long-haul (6-12 hour flight duration) or medium-haul (3-6 hour flight duration) flights to South Carolina. Instead, there are 16 short-haul flights (up to 3 hour flight duration), with the most arriving from St. Louis.

  • What are the most popular destinations in South Carolina?

    Based on KAYAK flight searches, the most popular destination is Charlotte (35% of total searches to South Carolina). The next most popular destinations are Myrtle Beach (18%) and Charleston (16%). Searches for flights to Savannah (13%), to Columbia (7%) and to Hilton Head Island (4%) are also popular.

Reviews of the top 4 airlines serving from Missouri to South Carolina

 
Need help choosing which airline to fly with from Missouri to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4245 reviews
7.5Entertainment
7.0Food
8.6Crew
8.0Comfort
8.1Boarding
Airline reviews

Over a 3 hour flight. The turbulence was almost imperceptible except for 2 short periods which were not bad and over quickly. The attendants claimed "Safety first" and sat looking at their phones for 3 hours with no drink or snack service. This isn't the first time with Southwest. I thinkit may be there new plan of operation. Oh, and it was June 18, Southwest's Birthday which offered free drinks. NOT.

4.0 OkayJeff, Jun 2026
MCI - FLL
Read more Southwest reviews

Over a 3 hour flight. The turbulence was almost imperceptible except for 2 short periods which were not bad and over quickly. The attendants claimed "Safety first" and sat looking at their phones for 3 hours with no drink or snack service. This isn't the first time with Southwest. I thinkit may be there new plan of operation. Oh, and it was June 18, Southwest's Birthday which offered free drinks. NOT.

I'm glad it wasn't only 75% full because I could get a good seat

The flight was okay. The pilots did an amazing job and kept us updated on the flight. The flight attendants were okay. They found time to be chatty with each other rather than focus on the guests. One of the attendants was a little less warm when asking about my bag I had on my lap that I was using during latter part of the mid- flight. Mind you, it was not the departure descent. I’m respectful to each and every attendant, it was the tone in her voice reminding me to place my carryon bag on the floor. I hope to have a better experience next time.

Snacks are always pretzels. Why can't you also offer peanuts ?

Only downside was the legroom and seat width, which is always a problem unless I spend more for a premium seat.

Pretty seamless, just a tad bit late in taking off and landing.

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

Everything a cheap airline should be at normal airline rates.

Delays delays delays. Late taking off, late landing, wait for a gate, etc.

Very good. Sad to learn Southwest is going start to charge for bags

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

From checking to boarding, it was a seamless experience. The service agents were so helpful. The flight crew was so pleasant.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

I am still at the Airport! Delayed Delayed and Delyaed

Delta has too many delays now days. It is 1:06 am now. I was supposed to land in Norfolk at 10:30 pm. I got re-booked through Detroit and I’m still in Detroit. I hope to be landed in Norfolk by 3am. I’ve been in airports for 12 hours as of right now. There is a weather delay now but most delays lately have been maintenance.

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

Awful. No counter attendants. No dinner offered due to delays.

Fine not above and beyond as I had a connection that was delayed due to maintenance

HORRIBLE, my initial flight was cancelled, they made me pay $200 extra dollars and that got cancelled as well! After 6 cancellations I decided to get a refund because I needed to get home to my babies. Out of $1000+ dollars they offered me only $40 in refund! Totally unacceptable! The flight that they cancelled I was able to fly it on another airline. I had to spend $400 on one way tickets just to get home! I’m still getting the runaround.

Flight was delayed. De-icing took a while. When we landed had to wait for another plane to vacate our gate. Just an overall bad experience.

Flight was delayed only slightly before takeoff due to traffic control. However, the flight arrived early to ORD. Good flight. United has been very reliable for me.

Our flight was understandably diverted to a small regional airport in Laramie, Wyoming due to weather conditions, which I fully recognize and appreciate. However, the low rating stems from the experience that followed: passengers remained on board for over an hour without the option to deplane and stretch, despite the aircraft being stationary. Although the pilot opened the cabin door, only he was permitted to exit. Meanwhile, passengers grew increasingly uncomfortable as warm summer air entered the cabin through the open door, and being in the second row meant we were impacted immediately. While the flight attendants made efforts to keep everyone at ease, I believe allowing passengers to deplane briefly, given the extended delay, would have significantly improved the overall experience.

Overall a very poor experience - booked premium economy tickets but due to last minute flight delays , all my itinery went for a toss and had to fly economy class with no access to lounge or any compensation by united airlines to make up for the flight delays . i had expected better experience than that from united.

Flight was canceled 12 hours before take-off due to “weather”

We were told our seats were switched which put us in row 1 instead of 12. We were not able to keep our personal items with us. This caused us not to be able to have our gum to pop our ears and we weren’t able to get our iPads out due to the seat belt sign never turning off.

Boarding was quick and efficient. My screen didn’t come on and everyone else had theirs working so a little bummer but it was a short flight!

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

The wifi experience is awful. I had to try again and again, taking over 30 minutes, to connect to the wifi. I had to watch the same two ads over and over until I was finally successful. Once connected, it was anything but "high speed" and disconnected at least three times during the flight.

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Good crew and flight was on time. It’s a small plane with limited overhead luggage space. They said the overhead space was full and I had to check my bag. There was still space when I got on. Waiting for my checked luggage added 30 minutes to my trip. Not the end of the world but also not great.

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

Pros: "Nothing"
Cons: "Getting all my luggage. Allowing my wife and I to sit together"

Everything you need to know for your flight to South Carolina

Cabin class types available on flights to Missouri

Cabin classes available on flights to Missouri. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.