SYR - DSM

$162 Find Cheap Flights from Syracuse to Des Moines - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$379
Typical prices: $345-$498
American Airlines
Tue 9/25Thu 9/27
SYR - DSM • 1 stop
Cheapest one-way
$162
Typical prices: $280-$416
Allegiant Air
Fri 12/14
SYR - DSM • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Syracuse and Des Moines. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
December
Cheapest • 21% price drop
April
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Atlanta Hartsfield-Jackson (ATL)
Cheapest • Avg $298 (round-trip)
Detroit Metropolitan Wayne County (DTW)
Shortest trip • 4h 38m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Syracuse to Des Moines (SYR-DSM)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Syracuse to Des Moines

Fri, Sep 25 - Sun, Sep 27
American Airlines Logo
5:40 pm - 11:41 pmSYR  Syracuse Hancock Intl-DSM Des Moines
7h 01m1 stop Washington, D.C. Reagan-National
American Airlines Logo
6:00 am - 11:35 amDSM  Des Moines-SYR Syracuse Hancock Intl
4h 35m1 stop Washington, D.C. Reagan-National
$379American Airlines
Fri, Sep 25 - Mon, Sep 28
American Airlines Logo
5:40 pm - 11:41 pmSYR  Syracuse Hancock Intl-DSM Des Moines
7h 01m1 stop Washington, D.C. Reagan-National
American Airlines Logo
5:57 pm - 12:07 amDSM  Des Moines-SYR Syracuse Hancock Intl
5h 10m1 stop Chicago O'Hare Intl
$379American Airlines
Fri, Sep 25 - Tue, Sep 29
Delta Logo
12:11 pm - 7:15 pmSYR  Syracuse Hancock Intl-DSM Des Moines
8h 04m1 stop New York LaGuardia
Delta Logo
5:59 pm - 11:47 pmDSM  Des Moines-SYR Syracuse Hancock Intl
4h 48m1 stop Minneapolis St Paul
$379Delta
Fri, Sep 25 - Tue, Sep 29
American Airlines Logo
5:40 pm - 11:41 pmSYR  Syracuse Hancock Intl-DSM Des Moines
7h 01m1 stop Washington, D.C. Reagan-National
American Airlines Logo
7:05 am - 5:10 pmDSM  Des Moines-SYR Syracuse Hancock Intl
9h 05m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National
$384American Airlines
Tue, Sep 29 - Sat, Oct 3
United Airlines Logo
6:10 am - 10:31 amSYR  Syracuse Hancock Intl-DSM Des Moines
5h 21m1 stop Chicago O'Hare Intl
United Airlines Logo
1:27 pm - 11:36 pmDSM  Des Moines-SYR Syracuse Hancock Intl
9h 09m1 stop Denver Intl
$399United Airlines
Sat, Oct 17 - Sun, Oct 18
Delta Logo
6:22 am - 9:42 amSYR  Syracuse Hancock Intl-DSM Des Moines
4h 20m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:00 am - 1:01 pmDSM  Des Moines-SYR Syracuse Hancock Intl
6h 01m1 stop Detroit Metropolitan Wayne County
$404Delta
Tue, Sep 29 - Sat, Oct 3
United Airlines Logo
5:50 pm - 9:23 pmSYR  Syracuse Hancock Intl-DSM Des Moines
4h 33m1 stop Chicago O'Hare Intl
United Airlines Logo
6:00 am - 2:19 pmDSM  Des Moines-SYR Syracuse Hancock Intl
7h 19m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$404United Airlines
Fri, Oct 16 - Sun, Oct 18
Delta Logo
6:22 am - 9:42 amSYR  Syracuse Hancock Intl-DSM Des Moines
4h 20m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:00 am - 1:01 pmDSM  Des Moines-SYR Syracuse Hancock Intl
6h 01m1 stop Detroit Metropolitan Wayne County
$484Delta
Mon, Sep 28 - Fri, Oct 2
Multiple Airlines Logo
9:24 am - 8:41 pmSYR  Syracuse Hancock Intl-DSM Des Moines
12h 17m1 stop Las Vegas Harry Reid Intl
Multiple Airlines Logo
3:09 pm - 10:37 amDSM  Des Moines-SYR Syracuse Hancock Intl
18h 28m1 stop Fort Myers SW Florida Intl
$630Multiple Airlines
Thu, Nov 26 - Sun, Nov 29
Allegiant Air Logo
12:40 pm - 10:11 amSYR  Syracuse Hancock Intl-DSM Des Moines
22h 31m1 stop Tampa St. Petersburg
Allegiant Air Logo
9:20 pm - 3:41 pmDSM  Des Moines-SYR Syracuse Hancock Intl
17h 21m1 stop Nashville Intl
$662Allegiant Air
Booking Insights

Price, demand and travel trends for Syracuse to Des Moines flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Syracuse to Des Moines with more confidence.

How much is a round-trip flight from Syracuse to Des Moines?

Round-trip flights from Syracuse to Des Moines start at $379. Prices are typical for this route right now, with typical round-trip fares ranging from $345 to $498. The lowest price found in the past 5 days was $379 on American Airlines.

What is the cheapest month to fly from Syracuse to Des Moines?

  • December is the cheapest month to fly from Syracuse to Des Moines at $328 round-trip.
  • April ($599) and January ($589) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 82% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Syracuse to Des Moines flights

Low season

February

Cheapest flight

$162
Most popular time to fly with an average 44% increase in price.
Flight from Syracuse to Des Moines

When to book flights from Syracuse to Des Moines

Are your dates flexible? Find out the best times to travel from Syracuse to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Syracuse to Des Moines flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Syracuse to Des Moines?

    Flights from Syracuse to Des Moines usually depart from Syracuse Hancock Intl (SYR) and arrive at Des Moines (DSM).

  • What cabin classes can I book on flights from Syracuse to Des Moines?

    Two cabin classes are available on flights from Syracuse to Des Moines:

    • Economy Class
    • First Class

  • Which airports do connecting flights from Syracuse to Des Moines pass through?

    One-stop flights from Syracuse to Des Moines most commonly connect through:

    • Chicago O'Hare Intl (ORD) - 49% of one-stop connections
    • Detroit Metropolitan Wayne County (DTW) - 38% of one-stop connections
    • Charlotte Douglas (CLT) - 5% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 4% of one-stop connections

    Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Syracuse to Des Moines?

    Yes. Being flexible with your travel dates can save you up to 30% on the Syracuse to Des Moines route. Wednesday is the cheapest departure day at $364 round-trip on average, while Monday is the most expensive at $516, a difference of $152. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Des Moines?

    Some of the most popular sights in Des Moines are Iowa Events Center, UnityPoint Health - Des Moines and Des Moines Civic Center. These are among the most viewed places in Des Moines on KAYAK.

  • How long is a flight from Syracuse to Des Moines?

    A nonstop flight from Syracuse to Des Moines takes 0h 00m, covering 901 miles.

  • Do I need a passport to fly from Syracuse to Des Moines?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Syracuse to Des Moines changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $379 to $1,253. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Syracuse to Des Moines looking right now?

    One-way fares from Syracuse to Des Moines are currently lower than usual. Average one-way flight prices are about $324, which is 8% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Syracuse to Des Moines?

    Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 4h 38m, compared with 5h 06m via Minneapolis St Paul (MSP) and 5h 14m via Chicago O'Hare Intl (ORD).

  • What is the time difference between Syracuse and Des Moines?

    Des Moines is 1 hour behind Syracuse (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Des Moines Airport (DSM)?

    Des Moines Airport (DSM) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    • Hertz
    • Payless
    • Budget
    • Alamo
    • Avis

  • How much should I expect to pay for a Syracuse to Des Moines flight?

    Round-trip flights from Syracuse to Des Moines range from $345 to $498, with an average of $415 over the past 12 months. Anything below $345 counts as a good deal.

Your guide to booking Syracuse to Des Moines flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Wednesday departure instead of Monday. On this route, Wednesday flights average $364 - about $152 less than Monday (29% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Syracuse to Des Moines trip for December. Fares historically average $328 round-trip in that month - typically $271 less than the most expensive month, which is April (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Des Moines Airport.
    - Days Inn & Suites by Wyndham Des Moines Airport
    - Quality Inn & Suites Des Moines Airport
    - Holiday Inn Des Moines-Airport/Conf Center By IHG

More options for your flight from Syracuse to Des Moines

Complete your trip to Des Moines with a hotel stay or car rental

Car rentals in Des Moines
Hotels in Des Moines
Vacations in Des Moines