SYR - STL

$321 Find Cheap Flights from Syracuse to St. Louis - Compare and Save

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Everything you should know

Cheapest round-trip
$321
Typical prices: $307-$486
American Airlines
Sun 11/4Sun 11/11
SYR - STL • 1 stop
Cheapest one-way
$328
Typical prices: $238-$356
Multiple Airlines
Thu 11/29
SYR - STL • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Syracuse and St. Louis. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
18 weeks
in advance
Our data shows that travelers who book at least 18 weeks in advance save around 40% compared to booking last minute.
Insights
Insights
When to travel
October
Cheapest • 25% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Washington, D.C. Dulles Intl (IAD)
Cheapest • Avg $318 (round-trip)
Detroit Metropolitan Wayne County (DTW)
Shortest trip • 4h 30m (one-way)
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Insights
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We hope you love your trip to St. Louis!
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Flight Deals

Cheap Flights from Syracuse to St. Louis (SYR-STL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Syracuse to St. Louis

Wed, Nov 4 - Wed, Nov 11
American Airlines Logo
6:40 pm - 10:15 pmSYR  Syracuse Hancock Intl-STL Lambert-St Louis
4h 35m1 stop Chicago O'Hare Intl
American Airlines Logo
11:35 am - 6:06 pmSTL  Lambert-St Louis-SYR Syracuse Hancock Intl
5h 31m1 stop Chicago O'Hare Intl
$321American Airlines
Tue, Dec 22 - Wed, Dec 30
Delta Logo
7:19 pm - 11:55 pmSYR  Syracuse Hancock Intl-STL Lambert-St Louis
5h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
3:25 pm - 11:40 pmSTL  Lambert-St Louis-SYR Syracuse Hancock Intl
7h 15m1 stop Minneapolis St Paul
$321Delta
Wed, Dec 23 - Wed, Dec 30
Delta Logo
7:00 am - 11:52 amSYR  Syracuse Hancock Intl-STL Lambert-St Louis
5h 52m1 stop New York LaGuardia
Delta Logo
3:25 pm - 11:40 pmSTL  Lambert-St Louis-SYR Syracuse Hancock Intl
7h 15m1 stop Minneapolis St Paul
$321Delta
Sat, Oct 24 - Sun, Nov 1
Frontier Logo
5:31 pm - 11:13 pmSYR  Syracuse Hancock Intl-STL Lambert-St Louis
6h 42m1 stop Orlando
Frontier Logo
4:26 pm - 4:38 pmSTL  Lambert-St Louis-SYR Syracuse Hancock Intl
23h 12m1 stop Orlando
$330Frontier
Thu, Nov 19 - Sat, Nov 21
American Airlines Logo
6:00 am - 10:08 amSYR  Syracuse Hancock Intl-STL Lambert-St Louis
5h 08m1 stop Washington, D.C. Reagan-National
American Airlines Logo
11:24 am - 4:24 pmSTL  Lambert-St Louis-SYR Syracuse Hancock Intl
4h 00m1 stop Chicago O'Hare Intl
$330American Airlines
Wed, Dec 2 - Sun, Dec 6
American Airlines Logo
6:40 pm - 10:15 pmSYR  Syracuse Hancock Intl-STL Lambert-St Louis
4h 35m1 stop Chicago O'Hare Intl
American Airlines Logo
10:34 am - 4:59 pmSTL  Lambert-St Louis-SYR Syracuse Hancock Intl
5h 25m1 stop Washington, D.C. Reagan-National
$330American Airlines
Sun, Dec 20 - Sat, Dec 26
Delta Logo
12:54 pm - 6:19 pmSYR  Syracuse Hancock Intl-STL Lambert-St Louis
6h 25m1 stop Atlanta Hartsfield-Jackson
Delta Logo
3:25 pm - 11:39 pmSTL  Lambert-St Louis-SYR Syracuse Hancock Intl
7h 14m1 stop Minneapolis St Paul
$330Delta
Tue, Oct 6 - Sat, Oct 10
United Airlines Logo
6:00 am - 12:13 pmSYR  Syracuse Hancock Intl-STL Lambert-St Louis
7h 13m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
9:04 am - 4:54 pmSTL  Lambert-St Louis-SYR Syracuse Hancock Intl
6h 50m1 stop Chicago O'Hare Intl
$374United Airlines
Tue, Oct 6 - Sat, Oct 10
United Airlines Logo
6:00 am - 12:13 pmSYR  Syracuse Hancock Intl-STL Lambert-St Louis
7h 13m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
6:00 am - 2:19 pmSTL  Lambert-St Louis-SYR Syracuse Hancock Intl
7h 19m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
$426United Airlines
Tue, Dec 22 - Wed, Dec 30
Multiple Airlines Logo
9:54 am - 1:21 pmSYR  Syracuse Hancock Intl-STL Lambert-St Louis
28h 27m2 stops Nashville Intl Jonesboro
Multiple Airlines Logo
6:05 pm - 5:44 pmSTL  Lambert-St Louis-SYR Syracuse Hancock Intl
22h 39m1 stop Orlando
$476Multiple Airlines
Booking Insights

Price, demand and travel trends for Syracuse to St. Louis flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Syracuse to St. Louis with more confidence.

How much is a round-trip flight from Syracuse to St. Louis?

Round-trip flights from Syracuse to St. Louis start at $321. Prices are typical for this route right now, with typical round-trip fares ranging from $307 to $486. The lowest price found in the past 5 days was $321 on American Airlines.

What's the cheapest day of the week to fly from Syracuse to St. Louis?

Saturday is the cheapest day of the week to fly from Syracuse to St. Louis, it is 12% cheaper than the average day. Sunday is the most expensive day with flight prices 39% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Syracuse to St. Louis?

•October is the cheapest month to fly from Syracuse to St. Louis at $283 round-trip.
•November ($522) and April ($463) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 84% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Syracuse to St. Louis the cheapest?

Flights from Syracuse to St. Louis are cheapest 18 weeks before departure. Booking in this window typically costs about 40% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Syracuse to St. Louis flights

Low season

February

Cheapest flight

$321
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Syracuse to St. Louis

When to book flights from Syracuse to St. Louis

Are your dates flexible? Find out the best times to travel from Syracuse to St. Louis based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Syracuse to St. Louis flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • What cabin classes can I book on flights from Syracuse to St. Louis?

    Two cabin classes are available on flights from Syracuse to St. Louis:

    • Economy Class
    • First Class

  • How long is a flight from Syracuse to St. Louis?

    A nonstop flight from Syracuse to St. Louis takes 0h 00m, covering 801 miles.

  • Do I need a passport to fly from Syracuse to St. Louis?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • How much should I expect to pay for a Syracuse to St. Louis flight?

    Round-trip flights from Syracuse to St. Louis range from $307 to $486, with an average of $376 over the past 12 months. Anything below $307 counts as a good deal.

  • How expensive are last-minute Syracuse to St. Louis flights?

    Last-minute fares on this route - booked within 2 weeks of departure - run 32% above the route average of $376. Book 18 weeks before departure for the lowest fares.

  • Have flight prices from Syracuse to St. Louis changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $321 to $1,769. That means the highest observed fare was about 6x higher than the lowest one.

  • How are flight prices from Syracuse to St. Louis looking right now?

    One-way fares from Syracuse to St. Louis are currently higher than usual. Average one-way flight prices are about $379, which is 28% above the typical average for this route.

  • What car rental options are available at Lambert-St Louis Airport (STL)?

    Lambert-St Louis Airport (STL) hosts 5 major car rental companies, with daily rates starting from around $31 for economy cars. Top options include:
    • Hertz
    • Budget
    • Alamo
    • Enterprise Rent-A-Car
    • Payless

  • Which airports can I use when flying from Syracuse to St. Louis?

    Flights from Syracuse to St. Louis usually depart from Syracuse Hancock Intl (SYR) and arrive at Lambert-St Louis (STL).

  • Which airports do connecting flights from Syracuse to St. Louis pass through?

    One-stop flights from Syracuse to St. Louis most commonly connect through:

    • Detroit Metropolitan Wayne County (DTW) - 47% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 30% of one-stop connections
    • Philadelphia (PHL) - 6% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 5% of one-stop connections

    Detroit Metropolitan Wayne County (DTW) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Syracuse to St. Louis?

    On the Syracuse to St. Louis route, being flexible with your departure day can save you up to 37%. Saturday is the cheapest day at $334 round-trip on average, while Sunday is the most expensive at $523: a $189 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How much time can I save by choosing a different layover airport from Syracuse to St. Louis?

    Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 4h 30m, compared with 5h 01m via Washington, D.C. Reagan-National (DCA) and 5h 03m via Washington, D.C. Dulles Intl (IAD).

  • What is the time difference between Syracuse and St. Louis?

    St. Louis is 1 hour behind Syracuse (Central Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in St. Louis?

    Some of the most popular sights in St. Louis are Busch Stadium, Enterprise Center and America's Center Convention Complex. These are among the most viewed places in St. Louis on KAYAK.

Your guide to booking Syracuse to St. Louis flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Saturday departure instead of Sunday. On this route, Saturday flights average $334 - about $189 less than Sunday (36% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 18 weeks before you fly. On this route, that window historically saves about 40% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Syracuse to St. Louis trip for October. Fares historically average $283 round-trip in that month - typically $239 less than the most expensive month, which is November (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Lambert-St Louis Airport.
    - Drury Inn & Suites St. Louis Airport
    - Renaissance St. Louis Airport Hotel
    - DoubleTree by Hilton St. Louis Airport

More options for your flight from Syracuse to St. Louis

Complete your trip to St. Louis with a hotel stay or car rental

Car rentals in St. Louis
Hotels in St. Louis
Vacations in St. Louis