TPA - VVI

$341 Find Cheap Flights from Tampa to Santa Cruz de la Sierra - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Tampa to Santa Cruz de la Sierra departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$595
United Airlines
Mon 10/26Thu 10/29
TPA - VVI • 2 stops
Cheapest one-way
$341
Typical prices: $279-$470
Multiple Airlines
Mon 8/17
TPA - VVI • 2 stops
Top airlines
Cheapest • from $595 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Tampa and Santa Cruz de la Sierra. You'll need at least 1 connection.
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We hope you love your trip to Santa Cruz de la Sierra!
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Flight Deals

Cheap Flights from Tampa to Santa Cruz de la Sierra (TPA-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Tampa to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Tampa to Santa Cruz de la Sierra

Mon, Oct 26 - Thu, Oct 29
United Airlines Logo
6:35 pm - 10:44 pmTPA  Tampa-VVI Santa Cruz de la Sierra Viru Viru Intl
28h 09m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:55 am - 10:34 amVVI  Santa Cruz de la Sierra Viru Viru Intl-TPA Tampa
46h 39m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$595United Airlines
Mon, Dec 7 - Sat, Dec 12
Copa Airlines Logo
4:51 am - 10:48 pmTPA  Tampa-VVI Santa Cruz de la Sierra Viru Viru Intl
16h 57m1 stop Panama City Tocumen Intl
Copa Airlines Logo
1:10 am - 3:20 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-TPA Tampa
15h 10m1 stop Panama City Tocumen Intl
$818Copa Airlines
Mon, Aug 17 - Mon, Aug 24
Multiple Airlines Logo
7:00 am - 10:40 pmTPA  Tampa-VVI Santa Cruz de la Sierra Viru Viru Intl
39h 40m2 stops Newark Panama City Tocumen Intl
Multiple Airlines Logo
11:47 am - 11:33 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-TPA Tampa
35h 46m2 stops Panama City Tocumen Intl Newark
$833Multiple Airlines
Tue, Dec 8 - Sat, Dec 12
Copa Airlines Logo
9:40 am - 3:42 amTPA  Tampa-VVI Santa Cruz de la Sierra Viru Viru Intl
17h 02m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
Copa Airlines Logo
1:10 am - 5:37 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-TPA Tampa
17h 27m1 stop Panama City Tocumen Intl
$840Copa Airlines
Mon, Aug 17 - Mon, Aug 24
Copa Airlines Logo
3:27 pm - 3:35 amTPA  Tampa-VVI Santa Cruz de la Sierra Viru Viru Intl
12h 08m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:47 am - 11:05 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-TPA Tampa
11h 18m1 stop Panama City Tocumen Intl
$841Copa Airlines
Mon, Aug 17 - Sun, Aug 23
Multiple Airlines Logo
3:27 pm - 3:35 amTPA  Tampa-VVI Santa Cruz de la Sierra Viru Viru Intl
12h 08m1 stop Panama City Tocumen Intl
Multiple Airlines Logo
3:35 am - 8:08 amVVI  Santa Cruz de la Sierra Viru Viru Intl-TPA Tampa
28h 33m2 stops Bogotá El Dorado Fort Lauderdale
$947Multiple Airlines
Tue, Dec 8 - Sat, Dec 12
Multiple Airlines Logo
7:15 am - 3:42 amTPA  Tampa-VVI Santa Cruz de la Sierra Viru Viru Intl
19h 27m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
Multiple Airlines Logo
1:10 am - 5:37 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-TPA Tampa
17h 27m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$954Multiple Airlines
Fri, Nov 20 - Sun, Nov 29
Multiple Airlines Logo
2:30 pm - 8:25 pmTPA  Tampa-VVI Santa Cruz de la Sierra Viru Viru Intl
28h 55m2 stops Panama City Tocumen Intl Sao Paulo Guarulhos Intl
Multiple Airlines Logo
1:40 pm - 3:27 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-TPA Tampa
26h 47m2 stops Sao Paulo Guarulhos Intl Panama City Tocumen Intl
$1,002Multiple Airlines
Fri, Nov 20 - Sun, Nov 29
Multiple Airlines Logo
2:55 pm - 8:35 amTPA  Tampa-VVI Santa Cruz de la Sierra Viru Viru Intl
16h 40m2 stops Bogotá El Dorado La Paz El Alto Intl
Multiple Airlines Logo
5:35 am - 1:25 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-TPA Tampa
32h 50m3 stops La Paz El Alto Intl Cusco Velazco Astete Bogotá El Dorado
$1,035Multiple Airlines
Mon, Oct 26 - Wed, Oct 28
Avianca Logo
3:55 pm - 2:35 amTPA  Tampa-VVI Santa Cruz de la Sierra Viru Viru Intl
10h 40m1 stop Bogotá El Dorado
Avianca Logo
3:40 am - 2:25 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-TPA Tampa
10h 45m1 stop Bogotá El Dorado
$1,072Avianca
Booking Insights

KAYAK's insights & trends for Tampa to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Tampa to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Tampa to Santa Cruz de la Sierra?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Tampa to Santa Cruz de la Sierra were found on United Airlines ($595) and Copa Airlines ($818).

Good to know

Cheapest flight

$341
Flight from Tampa to Santa Cruz de la Sierra

When to book flights from Tampa to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Tampa to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Tampa to Santa Cruz de la Sierra

  • What is the cheapest flight from Tampa to Santa Cruz de la Sierra?

    In the last 5 days, the lowest price for a flight from Tampa to Santa Cruz de la Sierra was $341 for a one-way ticket and $595 for a round-trip.

  • Do I need a passport to fly between Tampa and Santa Cruz de la Sierra?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Tampa and on arrival in Santa Cruz de la Sierra.

  • Which airports will I be using when flying from Tampa to Santa Cruz de la Sierra?

    Tampa and Santa Cruz de la Sierra are both served by 1 main airport. You will leave Tampa from Tampa and will be arriving at Santa Cruz de la Sierra Viru Viru Intl.

  • Which aircraft models fly most regularly from Tampa to Santa Cruz de la Sierra?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Tampa to Santa Cruz de la Sierra?

    Star Alliance is the only airline alliance operating flights between Tampa and Santa Cruz de la Sierra.

  • How does KAYAK find such low prices on flights from Tampa to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Tampa to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Tampa to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Tampa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Tampa to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Tampa with another airline. Booking your flights between Tampa and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Tampa to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Tampa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Tampa to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Tampa to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Tampa to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1563 reviews
7.8Boarding
6.8Entertainment
7.4Comfort
6.9Food
8.1Crew
Airline reviews

We where skipped for this flight will not head to Panama until tonight..

2.0 MediocreRussell, Jul 2026
Read more Copa Airlines reviews

We where skipped for this flight will not head to Panama until tonight..

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

This airline doesn’t five and dime you for everything. I do think that a checked bag should be included in every fare.

LOCKED MY BAG WITHOUT CONSENT. Had to have my zippers cut upon arrival in Costa Rica.

Everything you need to know for your flight from Tampa to Santa Cruz de la Sierra

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