PRG - DSM

$1,132 Find Cheap Flights from Prague to Des Moines - Compare and Save

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Cheap Flights from Prague to Des Moines (PRG-DSM)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Prague to Des Moines

Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
7:05 am - 5:28 pmPRG  Václav Havel Prague-DSM Des Moines
17h 23m2 stops Frankfurt am Main Chicago O'Hare Intl
United Airlines Logo
6:45 pm - 4:05 pmDSM  Des Moines-PRG Václav Havel Prague
14h 20m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
$1,132United Airlines
Fri, Nov 13 - Tue, Nov 17
Lufthansa Logo
10:20 am - 10:59 pmPRG  Václav Havel Prague-DSM Des Moines
19h 39m2 stops Frankfurt am Main Chicago O'Hare Intl
Lufthansa Logo
6:45 pm - 4:05 pmDSM  Des Moines-PRG Václav Havel Prague
14h 20m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
$1,137Lufthansa
Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
7:05 am - 9:55 pmPRG  Václav Havel Prague-DSM Des Moines
21h 50m2 stops Frankfurt am Main Chicago O'Hare Intl
United Airlines Logo
11:22 am - 1:05 pmDSM  Des Moines-PRG Václav Havel Prague
18h 43m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
$1,146United Airlines
Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
7:05 am - 9:55 pmPRG  Václav Havel Prague-DSM Des Moines
21h 50m2 stops Frankfurt am Main Chicago O'Hare Intl
United Airlines Logo
11:22 am - 1:05 pmDSM  Des Moines-PRG Václav Havel Prague
18h 43m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
$1,150United Airlines
Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
7:05 am - 7:16 pmPRG  Václav Havel Prague-DSM Des Moines
19h 11m2 stops Frankfurt am Main Chicago O'Hare Intl
United Airlines Logo
11:22 am - 2:00 pmDSM  Des Moines-PRG Václav Havel Prague
19h 38m2 stops Chicago O'Hare Intl Frankfurt am Main
$1,152United Airlines
Thu, Nov 12 - Mon, Nov 16
United Airlines Logo
7:05 am - 5:28 pmPRG  Václav Havel Prague-DSM Des Moines
17h 23m2 stops Frankfurt am Main Chicago O'Hare Intl
United Airlines Logo
6:45 pm - 4:05 pmDSM  Des Moines-PRG Václav Havel Prague
14h 20m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss
$1,154United Airlines
Fri, Nov 13 - Tue, Nov 17
Air Canada Logo
10:20 am - 9:55 pmPRG  Václav Havel Prague-DSM Des Moines
18h 35m3 stops Frankfurt am Main Toronto Pearson Intl Chicago O'Hare Intl
Air Canada Logo
9:55 am - 9:40 amDSM  Des Moines-PRG Václav Havel Prague
16h 45m3 stops Chicago O'Hare Intl Toronto Pearson Intl Frankfurt am Main
$1,344Air Canada
Fri, Nov 13 - Tue, Nov 17
Multiple Airlines Logo
11:45 am - 10:59 pmPRG  Václav Havel Prague-DSM Des Moines
18h 14m2 stops Frankfurt am Main Chicago O'Hare Intl
Multiple Airlines Logo
11:22 am - 9:30 pmDSM  Des Moines-PRG Václav Havel Prague
27h 08m3 stops Chicago O'Hare Intl Frankfurt am Main Milan Malpensa
$3,168Multiple Airlines
Booking Insights

Price, demand and travel trends for Prague to Des Moines flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Which airline is the cheapest to fly from Prague to Des Moines?

United Airlines ($1,132) and Lufthansa ($1,137) are the cheapest airlines to fly round-trip from Prague to Des Moines according to KAYAK data over the last 5 days.

Key details for Prague to Des Moines flights

Cheapest flight

$1,132
Round-trip flight from Prague to Des Moines

When to book flights from Prague to Des Moines

Are your dates flexible? Find out the best times to travel from Prague to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Prague to Des Moines flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Do I need a passport to fly from Prague to Des Moines?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Prague to Des Moines changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $1,132 to $3,168. That means the highest observed fare was about 3x higher than the lowest one.

  • What car rental options are available at Des Moines Airport (DSM)?

    Des Moines Airport (DSM) hosts 5 major car rental companies, with daily rates averaging $81 for economy cars. Top options include:

    • Hertz
    • Payless
    • Budget
    • Alamo
    • Avis

  • Which airports can I use when flying from Prague to Des Moines?

    Flights from Prague to Des Moines usually depart from Václav Havel Prague (PRG) and arrive at Des Moines (DSM).

  • What is the time difference between Prague and Des Moines?

    Des Moines is 6 hours behind Prague (Central Time vs Central European Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Des Moines?

    Some of the most popular sights in Des Moines are UnityPoint Health - Des Moines, Science Center of Iowa and Hy Vee Hall. These are among the most viewed places in Des Moines on KAYAK.

Your guide to booking Prague to Des Moines flights

Get tips on when to book, when to fly and what to know before your trip.

More options for your flight from Prague to Des Moines

Complete your trip to Des Moines with a hotel stay or car rental